Phosphatidylinositol 3-kinase recruitment by p185(erbB-2) and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification

Cell Growth and Differentiation

Volumn 7, Issue 5, 1996, Pages 551-561

  Ram, Tracy G ^a   Ethier, Stephen P ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTYROSINE; PROTEIN P185; PROTEIN TYROSINE KINASE; SOMATOMEDIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOMA; BREAST EPITHELIUM; CARCINOMA CELL; CONTROLLED STUDY; ENZYME ACTIVATION; GENE AMPLIFICATION; HUMAN; HUMAN CELL; MITOGENESIS; ONCOGENE C ERB; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANTINEOPLASTIC AGENTS; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL DIVISION; DNA, NEOPLASM; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; EPITHELIUM; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, ERBB-2; GLYCOPROTEINS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MITOGENS; NEUREGULINS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTO-ONCOGENE PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TYROSINE;

EID: 0029824114     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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