Monocyclic β-Lactams: New structures for new biological activities

Current Medicinal Chemistry

Volumn 18, Issue 28, 2011, Pages 4265-4283

  Galletti, P ^a   Giacomini, D ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

lactam; Antibacterial; Antibiotics; Anticancer; Azetidinone; Biological activity; Cathepsin; Enzymatic inhibitors; HDAC; Heterocycles; HFAAH; Inhibitor activity; Monocyclic Lactams; PPAR; Tryptase

Indexed keywords

3 AMINOAZETIDINONE DERIVATIVE; 3 CHLOROAZETIDINONE DERIVATIVE; 4 CHLOROAZETIDINONE DERIVATIVE; ANTIFILARIAL AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; ANTITHROMBOCYTIC AGENT; APOPTOSIS INDUCING FACTOR; AZETIDINONE DERIVATIVE; AZTREONAM; BETA LACTAM DERIVATIVE; BMS 262084; BMS 354326; BMS 363131; CATHEPSIN K INHIBITOR; COMBRETASTATIN A4; EZETIMIBE; FATTY ACID AMIDASE INHIBITOR; HISTONE DEACETYLASE INHIBITOR; N [1 (1,3 BENZODIOXOL 5 YL)BUTYL] 3,3 DIETHYL 2 [4 [(4 METHYL 1 PIPERAZINYL)CARBONYL]PHENOXY] 4 OXO 1 AZETIDINECARBOXAMIDE; N ACYLAZETIDINONE DERIVATIVE; N BISAZETIDINONE DERIVATIVE; N THIOMETHYLAZETIDINONE DERIVATIVE; NEW DRUG; PROTEASOME INHIBITOR; TRYPTASE INHIBITOR; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASOPRESSIN ANTAGONIST;

BIOLOGICAL ACTIVITY; CHEMICAL MODIFICATION; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; REVIEW; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; ANTITUBERCULAR AGENTS; AZETIDINES; ENZYME INHIBITORS; MONOBACTAMS; VASOPRESSINS;

EID: 80052919698     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986711797200480     Document Type: Review

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