An asymmetric synthesis of L-694,458, a human leukocyte elastase inhibitor, via novel enzyme resolution of β-lactam esters

Journal of Organic Chemistry

Volumn 61, Issue 19, 1996, Pages 6575-6580

  Cvetovich, Raymond J ^a   Chartrain, Michel ^a   Hartner Jr , Frederick W ^a   Roberge, Christopher ^a   Amato, Joseph S ^a   Grabowski, Edward J J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTASE INHIBITOR; N [1 (1,3 BENZODIOXOL 5 YL)BUTYL] 3,3 DIETHYL 2 [4 [(4 METHYL 1 PIPERAZINYL)CARBONYL]PHENOXY] 4 OXO 1 AZETIDINECARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029839451     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo960618k     Document Type: Article

References (24)

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