Large ring 1,3-bridged 2-azetidinones: Experimental and theoretical studies

European Journal of Medicinal Chemistry

Volumn 44, Issue 5, 2009, Pages 2071-2080

  Urbach, Allan ^a   Dive, Georges ^b   Tinant, Bernard ^a   Duval, Valérie ^b   Marchand Brynaert, Jacqueline ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Ab initio reactivity; Bicyclic lactam; Conformational study; RCM reaction; Serine enzyme inhibition

Indexed keywords

1 (PENT 4 ENOYL) 3 [1 (PENT 4 ENOYLOXY)ETHYL] 4 (ACETOXY)AZETIDIN 2 ONE; 14 (ACETOXY) 11 (METHYL) 2,9,13 TRIOXO 10 OXA 1 AZA BICYCLO [10.1.1]TETRADEC 5 ENE; 14 (ACETOXY) 11 (METHYL) 2,9,13 TRIOXO 10 OXA 1 AZA BICYCLO [10.1.1]TETRADECANE; ACETOXY AZETIDINONE; AMIDE; AZETIDINONE DERIVATIVE; BACTERIAL ENZYME; CARBAPENEM; ENZYME; PENAM DERIVATIVE; UNCLASSIFIED DRUG;

AB INITIO CALCULATION; ACYLATION; ARTICLE; EXPERIMENTAL STUDY; HYDROLYSIS; RING CLOSING METATHESIS; THEORETICAL STUDY;

ANTI-BACTERIAL AGENTS; AZETIDINES; MOLECULAR CONFORMATION; PENICILLINS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 62549090567     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.10.016     Document Type: Article

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