메뉴 건너뛰기




Volumn 16, Issue 5, 2009, Pages 564-575

Current status of newer carbapenems

Author keywords

Biapenem; Carbapenems; Doripenem; Ertapenem; Imipenem; Meropenem; Panipenem; Tebipenem pivoxil

Indexed keywords

BIAPENEM; CEFEPIME; CEFTRIAXONE; CILASTATIN PLUS IMIPENEM; DORIPENEM; ERTAPENEM; IMIPENEM; MEROPENEM; PANIPENEM PLUS BETAMIPRON; PIPERACILLIN PLUS TAZOBACTAM; PLACEBO; TEBIPENEM PIVOXIL; TOMOPENEM; ANTIINFECTIVE AGENT; CARBAPENEM DERIVATIVE;

EID: 63149127459     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709787458498     Document Type: Review
Times cited : (52)

References (152)
  • 1
    • 38349046979 scopus 로고    scopus 로고
    • Meropenem activity against European isolates: Report on the MYSTIC (Meropenem Yearly Susceptibility Test Information Collection) 2006 results
    • Turner, P.J. Meropenem activity against European isolates: Report on the MYSTIC (Meropenem Yearly Susceptibility Test Information Collection) 2006 results. Diagn. Microbiol. Infect. Dis., 2008, 60, 185-92.
    • (2008) Diagn. Microbiol. Infect. Dis , vol.60 , pp. 185-192
    • Turner, P.J.1
  • 3
    • 0032581949 scopus 로고    scopus 로고
    • Structural Basis for Clinical Longevity of Carbapenem Antibiotics in the Face of Challenge by the Common Class A β-Lactamases from the Antibiotic-Resistant Bacteria
    • Maveyraud, L.; Mourey, L.; Kotra, LP.; Pedelacq, J.D.; Guillet, V.; Mobashery, S.; Samama, J.P. Structural Basis for Clinical Longevity of Carbapenem Antibiotics in the Face of Challenge by the Common Class A β-Lactamases from the Antibiotic-Resistant Bacteria. J. Am. Chem. Soc., 1998, 120, 9748-52.
    • (1998) J. Am. Chem. Soc , vol.120 , pp. 9748-9752
    • Maveyraud, L.1    Mourey, L.2    Kotra, L.P.3    Pedelacq, J.D.4    Guillet, V.5    Mobashery, S.6    Samama, J.P.7
  • 4
    • 0033783426 scopus 로고    scopus 로고
    • Livermore, D.M.; Neil, W. Carbapenemases: A problem in waiting? Curr. Opin. Microbiol., 2000, 3, 489-95.
    • Livermore, D.M.; Neil, W. Carbapenemases: A problem in waiting? Curr. Opin. Microbiol., 2000, 3, 489-95.
  • 7
    • 41549114683 scopus 로고    scopus 로고
    • Detection of plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in a strain of carbapenem-resistant Enterobacter cloacae
    • Cai, J.C.; Zhou, H.W.; Chen, G.X.; Zhang, R. Detection of plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in a strain of carbapenem-resistant Enterobacter cloacae. Zhonghua Yi Xue Za Zhi, 2008, 88, 135-8.
    • (2008) Zhonghua Yi Xue Za Zhi , vol.88 , pp. 135-138
    • Cai, J.C.1    Zhou, H.W.2    Chen, G.X.3    Zhang, R.4
  • 8
    • 38649120083 scopus 로고    scopus 로고
    • Plasmid-Mediated Carbapenem-Hydrolyzing {beta}-Lactamase KPC-2 in Klebsiella pneumoniae from Greece
    • Cuzon,G.; Naas, T.; Demachy, M.C.; Nordmann, P. Plasmid-Mediated Carbapenem-Hydrolyzing {beta}-Lactamase KPC-2 in Klebsiella pneumoniae from Greece. Antimicrob. Agents Chemother., 2008, 52, 796-7.
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 796-797
    • Cuzon, G.1    Naas, T.2    Demachy, M.C.3    Nordmann, P.4
  • 10
    • 0028906105 scopus 로고
    • Primary structure of OXA-3 and phylogeny of oxacillin-hydrolyzing class D beta-lactamases
    • Sanschagrin, F.; Couture, F.; Levesque, R.C. Primary structure of OXA-3 and phylogeny of oxacillin-hydrolyzing class D beta-lactamases. Antimicrob. Agents Chemother., 1995, 39, 887-93.
    • (1995) Antimicrob. Agents Chemother , vol.39 , pp. 887-893
    • Sanschagrin, F.1    Couture, F.2    Levesque, R.C.3
  • 14
    • 34547422759 scopus 로고    scopus 로고
    • Queenan, A.M.; Bush, K. Carbapenemases: The versatile beta-lactamases. Clin. Microbiol. Rev., 2007, 20, 440-58.
    • Queenan, A.M.; Bush, K. Carbapenemases: The versatile beta-lactamases. Clin. Microbiol. Rev., 2007, 20, 440-58.
  • 15
    • 33845460167 scopus 로고    scopus 로고
    • Meropenem in the treatment of complicated skin and soft tissue infections
    • Fish, D.N. Meropenem in the treatment of complicated skin and soft tissue infections. Ther. Clin. Risk Manag., 2006, 2, 401-15.
    • (2006) Ther. Clin. Risk Manag , vol.2 , pp. 401-415
    • Fish, D.N.1
  • 17
    • 0033862706 scopus 로고    scopus 로고
    • Beta-lactamases: Which ones are clinically important?
    • Rice, L.B.; Bonomo, R.A. Beta-lactamases: Which ones are clinically important? Drug Resist. Updates, 2000, 3, 178-89
    • (2000) Drug Resist. Updates , vol.3 , pp. 178-189
    • Rice, L.B.1    Bonomo, R.A.2
  • 18
    • 40949160541 scopus 로고    scopus 로고
    • Novel beta-lactam antibiotics and inhibitor combinations
    • Bassetti, M.; Righi, E.; Viscoli, C. Novel beta-lactam antibiotics and inhibitor combinations. Expert Opin. Investig. Drugs, 2008, 17, 285-96.
    • (2008) Expert Opin. Investig. Drugs , vol.17 , pp. 285-296
    • Bassetti, M.1    Righi, E.2    Viscoli, C.3
  • 19
    • 0030024032 scopus 로고    scopus 로고
    • Imipenem/cilastatin: An update of its antibacterial activity, pharmacokinetics and therapeutic efficacy in the treatment of serious infections
    • Balfour, J.A.; Bryson, H.M.; Brogden, R.N. Imipenem/cilastatin: An update of its antibacterial activity, pharmacokinetics and therapeutic efficacy in the treatment of serious infections. Drugs, 1996, 51, 99-136.
    • (1996) Drugs , vol.51 , pp. 99-136
    • Balfour, J.A.1    Bryson, H.M.2    Brogden, R.N.3
  • 20
    • 40649109081 scopus 로고    scopus 로고
    • The role of carbapenems in the treatment of severe nosocomial respiratory tract infections
    • Joseph, J.; Rodvold, K.A. The role of carbapenems in the treatment of severe nosocomial respiratory tract infections. Expert Opin. Pharmacother., 2008, 9, 561-75.
    • (2008) Expert Opin. Pharmacother , vol.9 , pp. 561-575
    • Joseph, J.1    Rodvold, K.A.2
  • 21
    • 38849159205 scopus 로고    scopus 로고
    • Multidrug-resistant Gram-negative bacterial infections: The emerging threat and potential novel treatment options
    • Vergidis, P.I.; Falagas, M.E. Multidrug-resistant Gram-negative bacterial infections: The emerging threat and potential novel treatment options. Curr. Opin. Investig. Drugs, 2008, 9, 176-83.
    • (2008) Curr. Opin. Investig. Drugs , vol.9 , pp. 176-183
    • Vergidis, P.I.1    Falagas, M.E.2
  • 22
    • 0033804883 scopus 로고    scopus 로고
    • Comparative Pharmacokinetics of the Carbapenems: Clinical Implications
    • Mouton, J.; Touw, D.; Horrevorts, A.; Vinks, A. Comparative Pharmacokinetics of the Carbapenems: Clinical Implications. Clin. Pharmacokinetics, 2000, 39, 185-201.
    • (2000) Clin. Pharmacokinetics , vol.39 , pp. 185-201
    • Mouton, J.1    Touw, D.2    Horrevorts, A.3    Vinks, A.4
  • 23
    • 11844260120 scopus 로고    scopus 로고
    • Pharmacodynamic modeling of carbapenems and fluoroquinolones against bacteria that produce extended- spectrum beta-lactamases
    • Moczygemba, L.R. Frei, C.R.; Burgess, D.S. Pharmacodynamic modeling of carbapenems and fluoroquinolones against bacteria that produce extended- spectrum beta-lactamases. Clin. Ther., 2004, 26, 1800-7.
    • (2004) Clin. Ther , vol.26 , pp. 1800-1807
    • Moczygemba, L.R.1    Frei, C.R.2    Burgess, D.S.3
  • 26
    • 14744268018 scopus 로고    scopus 로고
    • In vitro activity of tebipenem, a new oral carbapenem antibiotic, against penicillin-nonsusceptible Streptococcus pneumoniae
    • Kobayashi, R.; Konomi, M.; Hasegawa, K.; Morozumi, M.; Sunakawa, K.; Ubukata, K. In vitro activity of tebipenem, a new oral carbapenem antibiotic, against penicillin-nonsusceptible Streptococcus pneumoniae. Antimicrob. Agents Chemother., 2005, 49, 889-94.
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 889-894
    • Kobayashi, R.1    Konomi, M.2    Hasegawa, K.3    Morozumi, M.4    Sunakawa, K.5    Ubukata, K.6
  • 28
    • 24344466955 scopus 로고    scopus 로고
    • Beta-lactams against methicillin-resistant Staphylococcus aureus
    • Guignard, B.; Entenza, J.M.; Moreillon, P. Beta-lactams against methicillin-resistant Staphylococcus aureus. Curr. Opin. Pharmacol., 2005, 5, 479-89.
    • (2005) Curr. Opin. Pharmacol , vol.5 , pp. 479-489
    • Guignard, B.1    Entenza, J.M.2    Moreillon, P.3
  • 29
    • 0028970114 scopus 로고
    • Antimicrobial activity of SM-17466, a novel carbapenem antibiotic with potent activity against methicillin-resistant Staphylococcus aureus
    • Sumita, Y.; Nouda, H.; Kanazawa, K.; Fukasawa, M. Antimicrobial activity of SM-17466, a novel carbapenem antibiotic with potent activity against methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother., 1995, 39, 910-6.
    • (1995) Antimicrob. Agents Chemother , vol.39 , pp. 910-916
    • Sumita, Y.1    Nouda, H.2    Kanazawa, K.3    Fukasawa, M.4
  • 30
    • 0042268094 scopus 로고    scopus 로고
    • In vitro and in vivo activities of novel 2- (thiazol-2-ylthio)-1beta-methylcarbapenems with potent activities against multiresistant gram-positive bacteria
    • Ueda, Y.; Sunagawa, M. In vitro and in vivo activities of novel 2- (thiazol-2-ylthio)-1beta-methylcarbapenems with potent activities against multiresistant gram-positive bacteria. Antimicrob. Agents Chemother., 2003, 47, 2471-80.
    • (2003) Antimicrob. Agents Chemother , vol.47 , pp. 2471-2480
    • Ueda, Y.1    Sunagawa, M.2
  • 32
    • 0030773905 scopus 로고    scopus 로고
    • Therapeutic efficacy of BO-3482, a novel dithiocarbamate carbapenem, in mice infected with methicillin-resistant Staphylococcus aureus
    • Nagano, R.; Shibata, K.; Naito, T.; Fuse, A.; Asano, K.; Hashizume, T.; Nakagawa, S. Therapeutic efficacy of BO-3482, a novel dithiocarbamate carbapenem, in mice infected with methicillin-resistant Staphylococcus aureus: Antimicrob. Agents Chemother., 1997, 41, 2278-81.
    • (1997) Antimicrob. Agents Chemother , vol.41 , pp. 2278-2281
    • Nagano, R.1    Shibata, K.2    Naito, T.3    Fuse, A.4    Asano, K.5    Hashizume, T.6    Nakagawa, S.7
  • 33
    • 48749127049 scopus 로고    scopus 로고
    • Potent in vitro Activity of Tomopenem (CS-023) against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa
    • Koga, T.; Masuda, N.; Kakuta, M.; Namba, E.; Sugihara, C.; Fukuoka, T. Potent in vitro Activity of Tomopenem (CS-023) against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa. Antimicrob. Agents Chemother., 2008, 52, 2849-54.
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 2849-2854
    • Koga, T.1    Masuda, N.2    Kakuta, M.3    Namba, E.4    Sugihara, C.5    Fukuoka, T.6
  • 34
    • 42049113177 scopus 로고    scopus 로고
    • Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection
    • MacGowan, A.P.; Bowker, K.E.; Noel, A.R. Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection. Antimicrob. Agents Chemother., 2008, 52, 1401-6.
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 1401-1406
    • MacGowan, A.P.1    Bowker, K.E.2    Noel, A.R.3
  • 36
    • 42049113177 scopus 로고    scopus 로고
    • Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection
    • Macgowan, A.P.; Bowker, K.E.; Noel, A.R. Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection. Antimicrob. Agents Chemother., 2008, 52, 1401-6.
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 1401-1406
    • Macgowan, A.P.1    Bowker, K.E.2    Noel, A.R.3
  • 38
    • 0036710297 scopus 로고    scopus 로고
    • Ertapenem monotherapy versus combination therapy with ceftriaxone plus metronidazole for treatment of complicated intra-abdominal infections in adults
    • Yellin, A.E.; Hassett, J.M.; Fernandez, A.; Geib, J.; Adeyi, B.; Woods, G.L.; Teppler, H. Ertapenem monotherapy versus combination therapy with ceftriaxone plus metronidazole for treatment of complicated intra-abdominal infections in adults. Int. J. Antimicrob. Agents, 2002, 20, 165-73.
    • (2002) Int. J. Antimicrob. Agents , vol.20 , pp. 165-173
    • Yellin, A.E.1    Hassett, J.M.2    Fernandez, A.3    Geib, J.4    Adeyi, B.5    Woods, G.L.6    Teppler, H.7
  • 39
    • 0037648561 scopus 로고    scopus 로고
    • Protocol 023 Study Group. Ertapenem once a day versus piperacillin-tazobactam every 6 hours for treatment of acute pelvic infections: A prospective, multicenter randomized, double-blind study
    • Roy, S.; Higareda, I.; Angel-Muller, E.; Ismail, M.; Hague, C.; Adeyi, B.; Woods, G.L.; Teppler, H. Protocol 023 Study Group. Ertapenem once a day versus piperacillin-tazobactam every 6 hours for treatment of acute pelvic infections: A prospective, multicenter randomized, double-blind study. Infect. Dis. Obstet. Gynecol., 2003, 11, 27-37.
    • (2003) Infect. Dis. Obstet. Gynecol , vol.11 , pp. 27-37
    • Roy, S.1    Higareda, I.2    Angel-Muller, E.3    Ismail, M.4    Hague, C.5    Adeyi, B.6    Woods, G.L.7    Teppler, H.8
  • 40
    • 0036292299 scopus 로고    scopus 로고
    • Protocol 021 Study GroupA prospective, multicenter, randomized, doble-blind study comparing ertapenem and ceftriaxone followed by appropriated oral therapy for complicated urinary tract infections in adults
    • Jimenez-Cruz, F.; Jasovich, A.; Cajigas, J.; Jiang, Q.; Imbeault, D.; Woods, G.L.; Gesser, R.M. Protocol 021 Study GroupA prospective, multicenter, randomized, doble-blind study comparing ertapenem and ceftriaxone followed by appropriated oral therapy for complicated urinary tract infections in adults. Urology, 2002, 60, 16-22.
    • (2002) Urology , vol.60 , pp. 16-22
    • Jimenez-Cruz, F.1    Jasovich, A.2    Cajigas, J.3    Jiang, Q.4    Imbeault, D.5    Woods, G.L.6    Gesser, R.M.7
  • 41
    • 0036604093 scopus 로고    scopus 로고
    • Ertapenem once daily versus piperacillin-tazobactam 4 times per day for treatment of complicated skin and skin-structure infections in adults: Results of a prospective, randomized, double-blind multicenter study
    • Graham, D.R.; Lucasti, C.; Malafaia, O.; Nichols, R.L.; Holtom, P.; Perez, N.Q.; McAdams, A.; Woods, G.L.; Ceesay, T.P.; Gesser, R. Ertapenem once daily versus piperacillin-tazobactam 4 times per day for treatment of complicated skin and skin-structure infections in adults: results of a prospective, randomized, double-blind multicenter study. Clin. Infect. Dis., 2002, 34, 1460-8.
    • (2002) Clin. Infect. Dis , vol.34 , pp. 1460-1468
    • Graham, D.R.1    Lucasti, C.2    Malafaia, O.3    Nichols, R.L.4    Holtom, P.5    Perez, N.Q.6    McAdams, A.7    Woods, G.L.8    Ceesay, T.P.9    Gesser, R.10
  • 42
    • 0036721176 scopus 로고    scopus 로고
    • Ertapenem versus ceftriaxone followed by appropriate oral therapy for treatment of complicated urinary tract infections in adults: Results of a prospective, randomized, double-blind multicenter study
    • Tomera, K.M.; Burdmann, E.A.; Reyna, O.G.; Jiang, Q.; Wimmer, W.M.; Woods, G.L.; Gesser, R.M. Ertapenem versus ceftriaxone followed by appropriate oral therapy for treatment of complicated urinary tract infections in adults: Results of a prospective, randomized, double-blind multicenter study. Antimicrob. Agents Chemother., 2002, 46, 2895-900.
    • (2002) Antimicrob. Agents Chemother , vol.46 , pp. 2895-2900
    • Tomera, K.M.1    Burdmann, E.A.2    Reyna, O.G.3    Jiang, Q.4    Wimmer, W.M.5    Woods, G.L.6    Gesser, R.M.7
  • 43
    • 27744552117 scopus 로고    scopus 로고
    • Ertapenem versus piperacillintazobactam for diabetic foot infections (SIDE-STEP); prospective, randomised, controlled, double-blind, multicenter trial
    • Lipsky, B.A.; Armstrong, D.G.; Citron, D.M.; Tice, A.D.; Morgenstern, D.E.; Abramson, M.A. Ertapenem versus piperacillintazobactam for diabetic foot infections (SIDE-STEP); prospective, randomised, controlled, double-blind, multicenter trial. Lancet, 2005, 366, 1695-703.
    • (2005) Lancet , vol.366 , pp. 1695-1703
    • Lipsky, B.A.1    Armstrong, D.G.2    Citron, D.M.3    Tice, A.D.4    Morgenstern, D.E.5    Abramson, M.A.6
  • 44
    • 0037090185 scopus 로고    scopus 로고
    • Protocol 018 Ertapenem Community-Acquired Pneumonia Study Group. A study evaluating the efficacy, safety and tolerability of ertapenem versus ceftriaxone for the treatment of community-acquired pneumonia in adults
    • Ortiz-Ruiz, G.; Caballero-Lopez, J.; Friedland, I.R.; Woods, G.L.; Carides, A. Protocol 018 Ertapenem Community-Acquired Pneumonia Study Group. A study evaluating the efficacy, safety and tolerability of ertapenem versus ceftriaxone for the treatment of community-acquired pneumonia in adults. Clin. Infect. Dis., 2002, 34, 1076-83.
    • (2002) Clin. Infect. Dis , vol.34 , pp. 1076-1083
    • Ortiz-Ruiz, G.1    Caballero-Lopez, J.2    Friedland, I.R.3    Woods, G.L.4    Carides, A.5
  • 45
    • 0036860282 scopus 로고
    • A prospective, randomized, double-blind multicenter comparison of parenteral ertapenem and ceftriaxone for the treatment of hospitalized adults with community- acquired pneumonia
    • Vetter, N.; Cambronero-Hernandez, E.; Rohlf, J.; Simon, S.; Carides, A.; Oliveria, T.; Isaacs, R. A prospective, randomized, double-blind multicenter comparison of parenteral ertapenem and ceftriaxone for the treatment of hospitalized adults with community- acquired pneumonia. Clin. Ther., 2002, 24, 1770-85.
    • (1770) Clin. Ther , vol.2002 , pp. 24
    • Vetter, N.1    Cambronero-Hernandez, E.2    Rohlf, J.3    Simon, S.4    Carides, A.5    Oliveria, T.6    Isaacs, R.7
  • 46
    • 18844415653 scopus 로고    scopus 로고
    • Comparative activity of doripenem and three other carbapenems tested against Gramnegative bacilli with various beta-lactamase resistance mechanisms
    • Jones, R.N.; Sader, H.S.; Fritsche, T.R. Comparative activity of doripenem and three other carbapenems tested against Gramnegative bacilli with various beta-lactamase resistance mechanisms. Diagn. Microbiol. Infect. Dis., 2005, 52, 71-4.
    • (2005) Diagn. Microbiol. Infect. Dis , vol.52 , pp. 71-74
    • Jones, R.N.1    Sader, H.S.2    Fritsche, T.R.3
  • 47
    • 28644447594 scopus 로고    scopus 로고
    • Antimicrobial activity of doripenem (S-4661): A global surveillance report (2003)
    • Fritsche, T.R.; Stillwell, M.G.; Jones, R.N. Antimicrobial activity of doripenem (S-4661): A global surveillance report (2003). Clin. Microbiol. Infect., 2005, 11, 974-84.
    • (2005) Clin. Microbiol. Infect , vol.11 , pp. 974-984
    • Fritsche, T.R.1    Stillwell, M.G.2    Jones, R.N.3
  • 48
    • 33845974650 scopus 로고    scopus 로고
    • Performance standards for antimicrobial susceptibility testing: Fifteenth informational supplement
    • Performance standards for antimicrobial susceptibility testing: fifteenth informational supplement. Clin. Lab. Standards Inst., 2005, 25, M100-S15.
    • (2005) Clin. Lab. Standards Inst , vol.25
  • 50
    • 3343024286 scopus 로고    scopus 로고
    • Role of β-lactamases and porins in resistance to ertapenem and other beta-lactams in Klebsiella pneumoniae
    • Jacoby, G.A.; Mills, D.M.; Chow, N. Role of β-lactamases and porins in resistance to ertapenem and other beta-lactams in Klebsiella pneumoniae Antimicrob. Agents Chemother., 2004, 48, 3203-6.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 3203-3206
    • Jacoby, G.A.1    Mills, D.M.2    Chow, N.3
  • 51
    • 21244488639 scopus 로고    scopus 로고
    • In vitro susceptibilities of aerobic and facultative Gram-negative bacilli isolated from patients with intraabdominal infections worldwide: The 2003 Study for Monitoring Antimicrobial Resistance trends (SMART)
    • Paterson, D.L.; Rossi, F.; Baquero, F.; Hsueh, P.R.; Woods, G.L.; Satishchandran, V.; Snyder, T.A.; Harvey, C.M.; Teppler, H.; Dinubile, M.J.; Chow, J.W. In vitro susceptibilities of aerobic and facultative Gram-negative bacilli isolated from patients with intraabdominal infections worldwide: The 2003 Study for Monitoring Antimicrobial Resistance trends (SMART). J. Antimicrob. Chemother., 2005, 55, 965-73.
    • (2005) J. Antimicrob. Chemother , vol.55 , pp. 965-973
    • Paterson, D.L.1    Rossi, F.2    Baquero, F.3    Hsueh, P.R.4    Woods, G.L.5    Satishchandran, V.6    Snyder, T.A.7    Harvey, C.M.8    Teppler, H.9    Dinubile, M.J.10    Chow, J.W.11
  • 52
    • 33947501712 scopus 로고    scopus 로고
    • Ertapenem in critically ill patients with early-onset ventilator-associated pneumonia: Pharmacokinetics with special consideration of free-drug concentration
    • Burkhardt, O.; Kumar, V.; Katterwe, D.; Majcher-Peszynska, J.; Drewelow, B.; Derendorf, H.; Welte, T. Ertapenem in critically ill patients with early-onset ventilator-associated pneumonia: Pharmacokinetics with special consideration of free-drug concentration. J. Antimicrob. Chemother., 2007, 59, 277-84.
    • (2007) J. Antimicrob. Chemother , vol.59 , pp. 277-284
    • Burkhardt, O.1    Kumar, V.2    Katterwe, D.3    Majcher-Peszynska, J.4    Drewelow, B.5    Derendorf, H.6    Welte, T.7
  • 53
    • 4644351577 scopus 로고    scopus 로고
    • Ertapenem pharmacokinetics and impact on intestinal microflora, in comparison to those of ceftriaxone, after multiple dosing in male and female volunteers
    • Pletz, M.W.; Rau, M.; Bulitta, J.; De Roux, A.; Burkhardt, O.; Kruse, G.; Kurowski, M.; Nord, C.E.; Lode, H. Ertapenem pharmacokinetics and impact on intestinal microflora, in comparison to those of ceftriaxone, after multiple dosing in male and female volunteers. Antimicrob. Agents Chemother., 2004, 48, 3765-72.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 3765-3772
    • Pletz, M.W.1    Rau, M.2    Bulitta, J.3    De Roux, A.4    Burkhardt, O.5    Kruse, G.6    Kurowski, M.7    Nord, C.E.8    Lode, H.9
  • 54
    • 34547841520 scopus 로고    scopus 로고
    • Efficacy of ertapenem in the treatment of early ventilator-associated pneumonia caused by extended-spectrum beta-lactamase-producing organisms in an intensive care unit
    • Bassetti, M.; Righi, E.; Fasce, R.; Molinari, M.P.; Rosso, R.; Di Biagio, A.; Mussap, M.; Pallavicini, F.B.; Viscoli, C. Efficacy of ertapenem in the treatment of early ventilator-associated pneumonia caused by extended-spectrum beta-lactamase-producing organisms in an intensive care unit. J. Antimicrob. Chemother., 2007, 60, 433-5.
    • (2007) J. Antimicrob. Chemother , vol.60 , pp. 433-435
    • Bassetti, M.1    Righi, E.2    Fasce, R.3    Molinari, M.P.4    Rosso, R.5    Di Biagio, A.6    Mussap, M.7    Pallavicini, F.B.8    Viscoli, C.9
  • 55
    • 0026732827 scopus 로고
    • Inactivation of new carbapenem antibiotics by dehydropeptidase-I from porcine and human renal cortex
    • Hikida, M.; Kawashima, K.; Yoshida, M. Inactivation of new carbapenem antibiotics by dehydropeptidase-I from porcine and human renal cortex. J. Antimicrob. Chemother, 1992, 30, 129-34.
    • (1992) J. Antimicrob. Chemother , vol.30 , pp. 129-134
    • Hikida, M.1    Kawashima, K.2    Yoshida, M.3
  • 56
    • 65649122948 scopus 로고    scopus 로고
    • Omegacin® (biapenem) prescribing information
    • Meiji. Omegacin® (biapenem) prescribing information. Kanagawa, Japan: Meiji, 2002.
    • (2002) Kanagawa, Japan: Meiji
    • Meiji1
  • 57
  • 58
    • 0030815865 scopus 로고    scopus 로고
    • Biapenem pharmacokinetics in healthy volunteers and in patients with impaired renal function
    • Koeppe, P.; Hoffler, D.; Fitzen, B. Biapenem pharmacokinetics in healthy volunteers and in patients with impaired renal function. Arzneimittelforschung, 1997, 47, 1250-6.
    • (1997) Arzneimittelforschung , vol.47 , pp. 1250-1256
    • Koeppe, P.1    Hoffler, D.2    Fitzen, B.3
  • 59
    • 0027764570 scopus 로고
    • In vitro activity of three carbapenem antibiotics. Comparative studies with biapenem (L-627), imipenem, and meropenem against aerobic pathogens isolated worldwide
    • Hoban, D.J.; Jones, R.N.; Yamane, N.; Frei, R.; Trilla, A.; Pignatari, A.C. In vitro activity of three carbapenem antibiotics. Comparative studies with biapenem (L-627), imipenem, and meropenem against aerobic pathogens isolated worldwide Diagn. Microbiol. Infect. Dis., 1993, 17, 299-305.
    • (1993) Diagn. Microbiol. Infect. Dis , vol.17 , pp. 299-305
    • Hoban, D.J.1    Jones, R.N.2    Yamane, N.3    Frei, R.4    Trilla, A.5    Pignatari, A.C.6
  • 61
    • 33748411070 scopus 로고    scopus 로고
    • Igari, J.; Watanabe, N.; Uehara, N.; Inoue, M.; Yoshida, H.; Imafuku, Y.; Nishino, T.; Shibano, T.; Satou, S.; Kobayashi, I.; Takahashi, A.; Yomoda, S.; Matsuoka, K.; Oguri, T.; Ohba, Y.; Kumasaka, K.; Tokuda, K.; Kobayashi, Y.; Hongo, T.; Okada, J.; Sasaki, T.; Matsumoto, N.; Hirata, Y.; Nakasaki, N.; Ono, J.; Takata, T.; Kawaguchi, R.; Ohtaki, Y.; Kajimura, K.; Ishigo, S.; Hashimoto, T.; Aoki, N.; Okamoto, E.; Murakami, E.; Saeki, H. Changes in the antibacterial activity of chemotherapeutic agents (especially carbapenems) for 10 species of clinical isolates between 1994 and 1996. Surveillance group of the sensitivities of clinical isolates to antibacterial agents. Jpn. J. Antibiot., 2000, 53, 157-70.
    • Igari, J.; Watanabe, N.; Uehara, N.; Inoue, M.; Yoshida, H.; Imafuku, Y.; Nishino, T.; Shibano, T.; Satou, S.; Kobayashi, I.; Takahashi, A.; Yomoda, S.; Matsuoka, K.; Oguri, T.; Ohba, Y.; Kumasaka, K.; Tokuda, K.; Kobayashi, Y.; Hongo, T.; Okada, J.; Sasaki, T.; Matsumoto, N.; Hirata, Y.; Nakasaki, N.; Ono, J.; Takata, T.; Kawaguchi, R.; Ohtaki, Y.; Kajimura, K.; Ishigo, S.; Hashimoto, T.; Aoki, N.; Okamoto, E.; Murakami, E.; Saeki, H. Changes in the antibacterial activity of chemotherapeutic agents (especially carbapenems) for 10 species of clinical isolates between 1994 and 1996. Surveillance group of the sensitivities of clinical isolates to antibacterial agents. Jpn. J. Antibiot., 2000, 53, 157-70.
  • 62
    • 0028989497 scopus 로고
    • The in-vitro activity of biapanem against 964 clinical isolates of aerobic bacteria
    • Raymond, N.J.; Bremner, D.A. The in-vitro activity of biapanem against 964 clinical isolates of aerobic bacteria. J. Antimicrob. Chemother., 1995, 35, 681-6.
    • (1995) J. Antimicrob. Chemother , vol.35 , pp. 681-686
    • Raymond, N.J.1    Bremner, D.A.2
  • 63
    • 0032784283 scopus 로고    scopus 로고
    • In vitro antibacterial activities of carbapenems against clinical isolates
    • Murase, M. In vitro antibacterial activities of carbapenems against clinical isolates. Jpn. J. Antibiot., 1999, 52, 667-79.
    • (1999) Jpn. J. Antibiot , vol.52 , pp. 667-679
    • Murase, M.1
  • 64
    • 0028347335 scopus 로고
    • Susceptibilities of 177 penicillin-susceptible and -resistant pneumococci to FK037, cefpirome, cefepime, ceftriaxone, cefotaxime, ceftazidime, imipenem, biapenem, meropenem, and vancomycin
    • Spangler, S.K.; Jacobs, M.R.; Appelbaum, P.C. Susceptibilities of 177 penicillin-susceptible and -resistant pneumococci to FK037, cefpirome, cefepime, ceftriaxone, cefotaxime, ceftazidime, imipenem, biapenem, meropenem, and vancomycin. Antimicrob. Agents Chemother., 1994, 38, 898-900.
    • (1994) Antimicrob. Agents Chemother , vol.38 , pp. 898-900
    • Spangler, S.K.1    Jacobs, M.R.2    Appelbaum, P.C.3
  • 65
    • 0034787019 scopus 로고    scopus 로고
    • Antimicrobial activities of carbapenems and forth generation cephems against clinically isolated strains
    • Suzuki, Y.; Nishinari, C.; Endo, H.; Tamura, C.; Jinbo, K. Antimicrobial activities of carbapenems and forth generation cephems against clinically isolated strains Jpn. J. Antibiot. 2001, 54, 473-90.
    • (2001) Jpn. J. Antibiot , vol.54 , pp. 473-490
    • Suzuki, Y.1    Nishinari, C.2    Endo, H.3    Tamura, C.4    Jinbo, K.5
  • 67
    • 0028263074 scopus 로고
    • Comparative in-vitro activity of biapenem against enterobacteria with beta-lactamase-mediated antibiotic resistance
    • Chen, H.Y.; Livermore, D.M. Comparative in-vitro activity of biapenem against enterobacteria with beta-lactamase-mediated antibiotic resistance. J. Antimicrob. Chemother., 1994, 33, 453-64.
    • (1994) J. Antimicrob. Chemother , vol.33 , pp. 453-464
    • Chen, H.Y.1    Livermore, D.M.2
  • 68
    • 0036324309 scopus 로고    scopus 로고
    • Annual changes is susceptibility of clinical isolates to biapenem
    • Hirakata, Y.; Matsuda, J.; Mochida, C. Annual changes is susceptibility of clinical isolates to biapenem. Jpn. J. Chemother., 2002, 50, 329-51.
    • (2002) Jpn. J. Chemother , vol.50 , pp. 329-351
    • Hirakata, Y.1    Matsuda, J.2    Mochida, C.3
  • 69
    • 0036186829 scopus 로고    scopus 로고
    • Comparison of in vitro activity of biapenem with other antimicrobial agents against clinical isolates of Pseudomonas aeruginosa
    • Ubukata, K.; Chiba, N.; Kobayashi, R. Comparison of in vitro activity of biapenem with other antimicrobial agents against clinical isolates of Pseudomonas aeruginosa. Chemother. Jpn., 2002, 50, 1-10.
    • (2002) Chemother. Jpn , vol.50 , pp. 1-10
    • Ubukata, K.1    Chiba, N.2    Kobayashi, R.3
  • 70
    • 0028572382 scopus 로고
    • In vitro antibacterial activity of biapenem against adherent bacteria
    • Miyake, Y.; Fujiwara, S.; Usui, T. In vitro antibacterial activity of biapenem against adherent bacteria. Chemother., 1994, 42, 82-90.
    • (1994) Chemother , vol.42 , pp. 82-90
    • Miyake, Y.1    Fujiwara, S.2    Usui, T.3
  • 71
    • 0028218752 scopus 로고
    • In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes
    • Aldridge, K.E.; Morice, N.; Schiro, D.D. In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes. Antimicrob. Agents Chemother., 1994, 38, 889-93.
    • (1994) Antimicrob. Agents Chemother , vol.38 , pp. 889-893
    • Aldridge, K.E.1    Morice, N.2    Schiro, D.D.3
  • 73
    • 0027250864 scopus 로고
    • Susceptibility of 539 gram-positive and gram-negative anaerobes to new agents, including RP59500, biapenem, trospectomycin and piperacillin/tazobactam
    • Appelbaum, P.C.; Spangler, S.K.; Jacobs, M.R. Susceptibility of 539 gram-positive and gram-negative anaerobes to new agents, including RP59500, biapenem, trospectomycin and piperacillin/tazobactam. J. Antimicrob. Chemother., 1993, 32, 223-31.
    • (1993) J. Antimicrob. Chemother , vol.32 , pp. 223-231
    • Appelbaum, P.C.1    Spangler, S.K.2    Jacobs, M.R.3
  • 74
    • 10544226874 scopus 로고    scopus 로고
    • Brismar, B.; Akerlund, J.E.; Sjöstedt, S.; Johansson, C.; Törnqvist, A.; Bäckstrand, B.; Bång, H., Andåker, L.; Gustafsson, P.O.; Darle, N.; Angerås, M.; Falk, A.; Tunevall, G.; Kasholm-Tengve, B.; Skau, T.; Nyström, P.O.; Gasslander, T.; Hagelbäck, A.; Olsson-Liljequist, B.; Eklund, A.E.; Nord, C.E. Biapenem versus imipenem/cilastatin in the treatment of complicated intraabdominal infections: Report from a Swedish Study. Scand. J. Infect. Dis., 1996, 28, 507-12.
    • Brismar, B.; Akerlund, J.E.; Sjöstedt, S.; Johansson, C.; Törnqvist, A.; Bäckstrand, B.; Bång, H., Andåker, L.; Gustafsson, P.O.; Darle, N.; Angerås, M.; Falk, A.; Tunevall, G.; Kasholm-Tengve, B.; Skau, T.; Nyström, P.O.; Gasslander, T.; Hagelbäck, A.; Olsson-Liljequist, B.; Eklund, A.E.; Nord, C.E. Biapenem versus imipenem/cilastatin in the treatment of complicated intraabdominal infections: Report from a Swedish Study. Scand. J. Infect. Dis., 1996, 28, 507-12.
  • 75
    • 0028912950 scopus 로고
    • A comparative study of biapenem and imipenem/cilastatin for chronic respiratory tract infections
    • Matsumoto, F.; Imai, T.; Sakurai, I. A comparative study of biapenem and imipenem/cilastatin for chronic respiratory tract infections Jpn. J. Chemother., 1995, 43, 63-84.
    • (1995) Jpn. J. Chemother , vol.43 , pp. 63-84
    • Matsumoto, F.1    Imai, T.2    Sakurai, I.3
  • 76
    • 0033972977 scopus 로고    scopus 로고
    • A comparative study of biapenem and imipemem/cilastatin in lower respiratory infections
    • Matsumoto, F.; Inoue, M.; Sakurai, I. A comparative study of biapenem and imipemem/cilastatin in lower respiratory infections. Jpn. J. Chemother., 2000, 48, 45-67.
    • (2000) Jpn. J. Chemother , vol.48 , pp. 45-67
    • Matsumoto, F.1    Inoue, M.2    Sakurai, I.3
  • 77
    • 65649153985 scopus 로고    scopus 로고
    • Panipenem/betamipron (Carbenin) prescribing information. Sankyo Co., Ltd. 2001.
    • Panipenem/betamipron (Carbenin) prescribing information. Sankyo Co., Ltd. 2001.
  • 78
    • 0027943664 scopus 로고
    • Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex
    • Hirouchi, Y.; Naganuma, H.; Kawahara, Y.; Okada, R.; Kamiya, A.; Inui, K.; Hori, R. Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex. Jpn. J. Pharmacol., 1994, 66, 1-6.
    • (1994) Jpn. J. Pharmacol , vol.66 , pp. 1-6
    • Hirouchi, Y.1    Naganuma, H.2    Kawahara, Y.3    Okada, R.4    Kamiya, A.5    Inui, K.6    Hori, R.7
  • 79
    • 0026732827 scopus 로고
    • Inactivation of new carbapenem antibiotics by dehydropeptidase-I from porcine and human renal cortex
    • Hikida, M.; Kawashima, K.; Yoshida, M.; Mitsuhashi, S. Inactivation of new carbapenem antibiotics by dehydropeptidase-I from porcine and human renal cortex.. J. Antimicrob. Chemother., 1992, 30, 129-34.
    • (1992) J. Antimicrob. Chemother , vol.30 , pp. 129-134
    • Hikida, M.1    Kawashima, K.2    Yoshida, M.3    Mitsuhashi, S.4
  • 80
    • 0025944240 scopus 로고
    • Antibacterial activity of panipenem, a new carbapenem antibiotic
    • Inoue, K.; Hamana, Y.; Mitsuhashi, S. Antibacterial activity of panipenem, a new carbapenem antibiotic. Chemotherapy, 1991, 39, 1-13.
    • (1991) Chemotherapy , vol.39 , pp. 1-13
    • Inoue, K.1    Hamana, Y.2    Mitsuhashi, S.3
  • 81
    • 0036236843 scopus 로고    scopus 로고
    • In vitro antibacterial activity of S-4661, a new parenteral carbapenem, against urological pathogens isolated from patients with complicated urinary tract infections
    • Nomura, S.; Nagayama, A. In vitro antibacterial activity of S-4661, a new parenteral carbapenem, against urological pathogens isolated from patients with complicated urinary tract infections. J. Chemother., 2002, 14, 155-60.
    • (2002) J. Chemother , vol.14 , pp. 155-160
    • Nomura, S.1    Nagayama, A.2
  • 83
    • 65649139528 scopus 로고
    • In vitro and in vivo activities clinical evaluation of panipenem/betamipron, a new carbapenem antibiotic
    • Fukuoka, T.; Inoue, H.; Abe, T.; Ohya, S. In vitro and in vivo activities clinical evaluation of panipenem/betamipron, a new carbapenem antibiotic. Chemotherapy, 1991, 39, 365-71.
    • (1991) Chemotherapy , vol.39 , pp. 365-371
    • Fukuoka, T.1    Inoue, H.2    Abe, T.3    Ohya, S.4
  • 84
    • 0025945149 scopus 로고
    • Laboratory and clinical studies on panipenem/betamipron
    • Higa, F.; Irabu, Y.; Fukuhara, H. Laboratory and clinical studies on panipenem/betamipron. Chemotherapy, 1991, 39, 449-54.
    • (1991) Chemotherapy , vol.39 , pp. 449-454
    • Higa, F.1    Irabu, Y.2    Fukuhara, H.3
  • 85
    • 0026004979 scopus 로고
    • In vitro antibacterial activity of panipenem/betamipron, a carbapenem antibiotic
    • Goto, Y.; Ichimiya, T.; Ikuta, M. In vitro antibacterial activity of panipenem/betamipron, a carbapenem antibiotic. Chemotherapy, 1991, 39, 441-8.
    • (1991) Chemotherapy , vol.39 , pp. 441-448
    • Goto, Y.1    Ichimiya, T.2    Ikuta, M.3
  • 86
    • 0025998685 scopus 로고
    • Antimicrobial activity and clinical evaluation of panipenem/betamipron in urinary tract infections
    • Goto, T.; Makinose, S.; Kawahara, M. Antimicrobial activity and clinical evaluation of panipenem/betamipron in urinary tract infections. Chemotherapy, 1991, 39, 512-20.
    • (1991) Chemotherapy , vol.39 , pp. 512-520
    • Goto, T.1    Makinose, S.2    Kawahara, M.3
  • 87
    • 0036236843 scopus 로고    scopus 로고
    • In vitro antibacterial activity of S-4661, a new parenteral carbapenem, against urological pathogens isolated from patients with complicated urinary tract infections
    • Nomura, S.; Nagayama, A. In vitro antibacterial activity of S-4661, a new parenteral carbapenem, against urological pathogens isolated from patients with complicated urinary tract infections. J. Chemother., 2002, 14, 155-60.
    • (2002) J. Chemother , vol.14 , pp. 155-160
    • Nomura, S.1    Nagayama, A.2
  • 88
    • 0026052531 scopus 로고
    • Study on postantibiotic effect (PAE) of panipenem/betamipron, a carbapenem antibiotic
    • Totsuka, K.; Kikuchi, K.; Shibata, Y. Study on postantibiotic effect (PAE) of panipenem/betamipron, a carbapenem antibiotic. Chemotherapy, 1991, 39, 78-82.
    • (1991) Chemotherapy , vol.39 , pp. 78-82
    • Totsuka, K.1    Kikuchi, K.2    Shibata, Y.3
  • 89
    • 0026590605 scopus 로고
    • Investigation of panipenem/betamipron levels in sera and various tissues in patients of orthopedic surgery
    • Kurata, K. Investigation of panipenem/betamipron levels in sera and various tissues in patients of orthopedic surgery. Jpn. J. Antibiot., 1992, 45, 155-9.
    • (1992) Jpn. J. Antibiot , vol.45 , pp. 155-159
    • Kurata, K.1
  • 90
    • 0025939025 scopus 로고
    • Clinical study on panipenem/betamipron in bacterial prostatitis
    • Suzuki, K.; Horiba, M.; Naide, Y. Clinical study on panipenem/betamipron in bacterial prostatitis. Chemotherapy, 1991, 39, 773-7.
    • (1991) Chemotherapy , vol.39 , pp. 773-777
    • Suzuki, K.1    Horiba, M.2    Naide, Y.3
  • 91
    • 0026052543 scopus 로고
    • Basic and clinical studies on panipenem/betamipron in obstetrics and gynecology
    • Yamamoto, T.; Yasuda, J.; Iwasaku, K. Basic and clinical studies on panipenem/betamipron in obstetrics and gynecology. Chemotherapy, 1991, 39, 636-46.
    • (1991) Chemotherapy , vol.39 , pp. 636-646
    • Yamamoto, T.1    Yasuda, J.2    Iwasaku, K.3
  • 92
    • 0026776988 scopus 로고
    • A comparative study of panipenem/ betamipron and imipenem/cilastatin in bacterial pneumonia
    • Hara, K.; Hiraga, Y.; Omichi, M. A comparative study of panipenem/ betamipron and imipenem/cilastatin in bacterial pneumonia. Chemotherapy, 1992, 40, 509-31.
    • (1992) Chemotherapy , vol.40 , pp. 509-531
    • Hara, K.1    Hiraga, Y.2    Omichi, M.3
  • 93
    • 0026780143 scopus 로고
    • A comparative study of panipenem/ betamipron and imipenem/cilastatin in respiratory tract infections
    • Hara, K.; Kouno, S.K.H., Takebe, K. A comparative study of panipenem/ betamipron and imipenem/cilastatin in respiratory tract infections. Chemotherapy, 1992, 40, 613-37.
    • (1992) Chemotherapy , vol.40 , pp. 613-637
    • Hara, K.1    Kouno, S.K.H.2    Takebe, K.3
  • 94
    • 0026607304 scopus 로고
    • Phase III comparative clinical trial of panipenem/betamipron (PAPM/BP) with imipenem/cilastatin sodium (IPM/CS) in complicaed urinary tract infections
    • Kumazawa, J.; Matsumoto, T.; Kumamoto, Y. Phase III comparative clinical trial of panipenem/betamipron (PAPM/BP) with imipenem/cilastatin sodium (IPM/CS) in complicaed urinary tract infections. Nishinihon J. Urol., 1992, 54, 254-71.
    • (1992) Nishinihon J. Urol , vol.54 , pp. 254-271
    • Kumazawa, J.1    Matsumoto, T.2    Kumamoto, Y.3
  • 95
    • 0031935991 scopus 로고    scopus 로고
    • Change of cytokines and clinical efficacy of panipenem/betamipron in obstetric and gynecological infections. Yamagata Study Group of Panipenem/Betamipron in Obstetric and Gynecological Infections
    • Chimura, T.; Oda, T.; Saito, N.; Morisaki, N.; Numasaki, M. Change of cytokines and clinical efficacy of panipenem/betamipron in obstetric and gynecological infections. Yamagata Study Group of Panipenem/Betamipron in Obstetric and Gynecological Infections. Jpn. J. Antibiot., 1998, 51, 37-45.
    • (1998) Jpn. J. Antibiot , vol.51 , pp. 37-45
    • Chimura, T.1    Oda, T.2    Saito, N.3    Morisaki, N.4    Numasaki, M.5
  • 96
    • 0025939862 scopus 로고
    • Fundamental and clinical studies of panipenem/betamipron in surgery
    • Yura, J.; Shinagawa, N.; Ishikawa, S. Fundamental and clinical studies of panipenem/betamipron in surgery. Chemotherapy, 1991, 39, 557-71.
    • (1991) Chemotherapy , vol.39 , pp. 557-571
    • Yura, J.1    Shinagawa, N.2    Ishikawa, S.3
  • 97
    • 0026561421 scopus 로고
    • Studies on the efficacy and safety of panipenem/betamipron in infections in surgical domain and the safety when mixed with lactate containing infusion
    • Tsuyuki, K.; Arisawa, Y.; Yokoyama, I. Studies on the efficacy and safety of panipenem/betamipron in infections in surgical domain and the safety when mixed with lactate containing infusion. Jpn. J. Antibiot., 1992, 45, 188-96.
    • (1992) Jpn. J. Antibiot , vol.45 , pp. 188-196
    • Tsuyuki, K.1    Arisawa, Y.2    Yokoyama, I.3
  • 98
    • 0026075108 scopus 로고
    • Study on surgical infections, especially intra-abdominal infections, postoperative infections, and skin and soft tissue infections:cLinical application of panipenem/ betamipron, a new carbapenem antibiotic for injection
    • Nakayama, I.; Yamaji, E.; Kawamura, H. Study on surgical infections, especially intra-abdominal infections, postoperative infections, and skin and soft tissue infections:cLinical application of panipenem/ betamipron, a new carbapenem antibiotic for injection. Chemotherapy, 1991, 39, 534-51.
    • (1991) Chemotherapy , vol.39 , pp. 534-551
    • Nakayama, I.1    Yamaji, E.2    Kawamura, H.3
  • 99
    • 39049131644 scopus 로고    scopus 로고
    • Panipenem Versus Cefepime as Empirical Monotherapy in Adult Cancer Patients with Febrile Neutropenia: A Prospective Randomized Trial
    • Kwon, K.; Cheong, H.S.; Rhee, J. Panipenem Versus Cefepime as Empirical Monotherapy in Adult Cancer Patients with Febrile Neutropenia: A Prospective Randomized Trial. Jap. J. Clin. Oncol., 2008, 38, 49-55.
    • (2008) Jap. J. Clin. Oncol , vol.38 , pp. 49-55
    • Kwon, K.1    Cheong, H.S.2    Rhee, J.3
  • 100
    • 0031923186 scopus 로고    scopus 로고
    • Clinical and bacteriological studies on panipenem/betamipron in pediatrics. Kanagawa Research Group for Infectious Diseases of Children
    • Kato, T.; Goshima, T.; Akita, H. Clinical and bacteriological studies on panipenem/betamipron in pediatrics. Kanagawa Research Group for Infectious Diseases of Children. Jpn. J. Antibiot., 1998, 51, 286-97.
    • (1998) Jpn. J. Antibiot , vol.51 , pp. 286-297
    • Kato, T.1    Goshima, T.2    Akita, H.3
  • 101
    • 0032811929 scopus 로고    scopus 로고
    • Discussion on the safety of panipenem/betamipron according to postmarketing surveillance
    • Anonymous
    • Anonymous. Discussion on the safety of panipenem/betamipron according to postmarketing surveillance. Jpn. J. Chemother., 1999, 47, 396-410.
    • (1999) Jpn. J. Chemother , vol.47 , pp. 396-410
  • 102
    • 0026776988 scopus 로고
    • A comparative study of panipenem/ betamipron and imipenem/cilastatin in bacterial pneumonia
    • Hara, K.; Hiraga, Y.; Omichi, M. A comparative study of panipenem/ betamipron and imipenem/cilastatin in bacterial pneumonia. Chemotherapy, 1992, 40, 509-31.
    • (1992) Chemotherapy , vol.40 , pp. 509-531
    • Hara, K.1    Hiraga, Y.2    Omichi, M.3
  • 103
    • 0029046103 scopus 로고
    • Structural features resulting in convulsive activity of carbapenem compounds: Effect of C-2 side chain
    • Sunagawa, M.; Matsumura, H.; Sumita, Y.; Nouda, H. Structural features resulting in convulsive activity of carbapenem compounds: Effect of C-2 side chain. J. Antibiot. (Tokyo), 1995, 48, 408-16.
    • (1995) J. Antibiot. (Tokyo) , vol.48 , pp. 408-416
    • Sunagawa, M.1    Matsumura, H.2    Sumita, Y.3    Nouda, H.4
  • 104
    • 0026731177 scopus 로고
    • Neurotoxicity of panipenem/betamipron, a new carbapenem, in rabbits: Correlation to concentration in central nervous system
    • Kurihara, A.; Hisaoka, M.; Mikuni, N.; Kamoshida, K. Neurotoxicity of panipenem/betamipron, a new carbapenem, in rabbits: Correlation to concentration in central nervous system. J. Pharmacobiodyn., 1992, 15, 325-32.
    • (1992) J. Pharmacobiodyn , vol.15 , pp. 325-332
    • Kurihara, A.1    Hisaoka, M.2    Mikuni, N.3    Kamoshida, K.4
  • 107
    • 65649154361 scopus 로고    scopus 로고
    • Peninsula Pharmaceuticals Inc. Peninsula Pharmaceuticals, Inc. announces results of preclinical study comparing nebulized doripenem vs tobramycin in a murine model of acute, severe Pseudomonas aeruginosa pneumonia. Available at: www.peninsulapharm.com. Accessed April 7, 2004.
    • Peninsula Pharmaceuticals Inc. Peninsula Pharmaceuticals, Inc. announces results of preclinical study comparing nebulized doripenem vs tobramycin in a murine model of acute, severe Pseudomonas aeruginosa pneumonia. Available at: www.peninsulapharm.com. Accessed April 7, 2004.
  • 108
    • 65649093265 scopus 로고    scopus 로고
    • Floren, L.; Wikler, M.; Kilfoil, T. A phase 1, double-blind, placebo-controlled study to determine the safety, tolerability, and pharmacokinetics of prolonged-infusion regimens of doripenem in healthy subjects. 44th Intersci. Conf. Antimicrob. Agents Chemother., 2004, PA-16.
    • Floren, L.; Wikler, M.; Kilfoil, T. A phase 1, double-blind, placebo-controlled study to determine the safety, tolerability, and pharmacokinetics of prolonged-infusion regimens of doripenem in healthy subjects. 44th Intersci. Conf. Antimicrob. Agents Chemother., 2004, PA-16.
  • 109
    • 3543061704 scopus 로고    scopus 로고
    • Doripenem (S-4661), a novel carbapenem: Comparative activity against contemporary pathogens including bactericidal action and preliminary in vitro methods evaluations
    • Jones, R.N.; Huynh, H.K.; Biedenbach, D.J.; Fritsche, T.R.; Sader, H.S. Doripenem (S-4661), a novel carbapenem: Comparative activity against contemporary pathogens including bactericidal action and preliminary in vitro methods evaluations. J. Antimicrob. Chemother., 2004, 54, 144-54.
    • (2004) J. Antimicrob. Chemother , vol.54 , pp. 144-154
    • Jones, R.N.1    Huynh, H.K.2    Biedenbach, D.J.3    Fritsche, T.R.4    Sader, H.S.5
  • 110
    • 36448983199 scopus 로고    scopus 로고
    • Peritoneal penetration of doripenem after intravenous administration in abdominal-surgery patients
    • Ikawa, K.; Morikawa, N.; Urakawa, N.; Ikeda, K.; Ohge, H.; Sueda, T. Peritoneal penetration of doripenem after intravenous administration in abdominal-surgery patients. J. Antimicrob. Chemother., 2007, 60, 1395-7.
    • (2007) J. Antimicrob. Chemother , vol.60 , pp. 1395-1397
    • Ikawa, K.1    Morikawa, N.2    Urakawa, N.3    Ikeda, K.4    Ohge, H.5    Sueda, T.6
  • 111
    • 0033625002 scopus 로고    scopus 로고
    • Comparative in vitro activity of S-4661, a new parenteral carbapenem, and other antimicrobial agents against respiratory pathogens
    • Watanabe, A.; Takahashi, H.; Kikuchi, T.; Kobayashi, T.; Gomi, K.; Fujimura, S.; Tokue, Y.; Nukiwa, T. Comparative in vitro activity of S-4661, a new parenteral carbapenem, and other antimicrobial agents against respiratory pathogens. Chemotherapy, 2000, 46, 184-87.
    • (2000) Chemotherapy , vol.46 , pp. 184-187
    • Watanabe, A.1    Takahashi, H.2    Kikuchi, T.3    Kobayashi, T.4    Gomi, K.5    Fujimura, S.6    Tokue, Y.7    Nukiwa, T.8
  • 112
    • 24144496190 scopus 로고    scopus 로고
    • Use of pharmacokinetic-pharmacodynamic target attainment analyses to support phase 2 and 3 dosing strategies for doripenem
    • Bhavnani, S.M.; Hammel, J.P.; Cirincione, B.B.; Wikler, M.A.; Ambrose, P.G. Use of pharmacokinetic-pharmacodynamic target attainment analyses to support phase 2 and 3 dosing strategies for doripenem. Antimicrob. Agents Chemother., 2005, 49, 3944-7.
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 3944-3947
    • Bhavnani, S.M.1    Hammel, J.P.2    Cirincione, B.B.3    Wikler, M.A.4    Ambrose, P.G.5
  • 113
    • 1642502313 scopus 로고    scopus 로고
    • Comparative activities of doripenem versus isolates, mutants, and transconjugants of Enterobacteriaceae and Acinetobacter spp. with characterized blactamases
    • Mushtaq, S.; Ge, Y.; Livermore, D.M. Comparative activities of doripenem versus isolates, mutants, and transconjugants of Enterobacteriaceae and Acinetobacter spp. with characterized blactamases. Antimicrob. Agents Chemother., 2004, 48, 1313-19.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 1313-1319
    • Mushtaq, S.1    Ge, Y.2    Livermore, D.M.3
  • 114
    • 0029060787 scopus 로고
    • Meropenem. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy
    • Wiseman, L.R.; Wagstaff, A.J.; Brogden, R.N.; Bryson, H.M.. Meropenem. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. Drugs, 1995, 50, 73-101.
    • (1995) Drugs , vol.50 , pp. 73-101
    • Wiseman, L.R.1    Wagstaff, A.J.2    Brogden, R.N.3    Bryson, H.M.4
  • 115
    • 3342910269 scopus 로고    scopus 로고
    • Activities of doripenem (S-4661) against drug-resistant clinical pathogens
    • Jones, R.N.; Huynh, H.K.; Biedenbach, D.J. Activities of doripenem (S-4661) against drug-resistant clinical pathogens. Antimicrob. Agents Chemother., 2004, 48, 3136-40.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 3136-3140
    • Jones, R.N.1    Huynh, H.K.2    Biedenbach, D.J.3
  • 116
    • 42449096715 scopus 로고    scopus 로고
    • Doripenem vs meropenem with an option for oral step-down therapy in the treatment of complicated intra-abdominal infections. 47th Intersci. Conf
    • Solomkin, J.; Umeh, O.; Jiang, J.; Kaniga, K.; Friedland, I. Doripenem vs meropenem with an option for oral step-down therapy in the treatment of complicated intra-abdominal infections. 47th Intersci. Conf. Antimicrob. Agents Chemother., 2007, L-487.
    • (2007) Antimicrob. Agents Chemother
    • Solomkin, J.1    Umeh, O.2    Jiang, J.3    Kaniga, K.4    Friedland, I.5
  • 118
    • 41649099025 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: A multicenter, randomized study
    • Chastre, J.; Wunderink, R.; Prokocimer, P.; Lee, M.; Kaniga, K.; Friedland, I. Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: A multicenter, randomized study. Crit. Care Med., 2008, 36, 1089-96.
    • (2008) Crit. Care Med , vol.36 , pp. 1089-1096
    • Chastre, J.1    Wunderink, R.2    Prokocimer, P.3    Lee, M.4    Kaniga, K.5    Friedland, I.6
  • 119
    • 38649113256 scopus 로고    scopus 로고
    • In vitro Activity of Doripenem and Six Comparator Drugs Against 423 Aerobic and Anaerobic Bacteria Isolated from Infected Diabetic Foot Wounds
    • Goldstein, E.J.; Citron, D.M.; Merriam, C.V.; Warren, Y.A.; Tyrrell, K.L.; Fernandez, H.T. In vitro Activity of Doripenem and Six Comparator Drugs Against 423 Aerobic and Anaerobic Bacteria Isolated from Infected Diabetic Foot Wounds. Antimicrob. Agents Chemother., 2008, 52, 761-6.
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 761-766
    • Goldstein, E.J.1    Citron, D.M.2    Merriam, C.V.3    Warren, Y.A.4    Tyrrell, K.L.5    Fernandez, H.T.6
  • 120
    • 34547685940 scopus 로고    scopus 로고
    • Maruyama, T.; Yamamoto, Y.; Kano, Y.; Kurazono, M.; Matsuhisa, E.; Takata, H.; Takata, T.; Atsumi, K.; Iwamatsu, K.; Shitara E. CP5484, a novel quaternary carbapenem with potent anti-MRSA activity and reduced toxicity. Bioorg. Med. Chem., 2007, 15, 6379- 7.
    • Maruyama, T.; Yamamoto, Y.; Kano, Y.; Kurazono, M.; Matsuhisa, E.; Takata, H.; Takata, T.; Atsumi, K.; Iwamatsu, K.; Shitara E. CP5484, a novel quaternary carbapenem with potent anti-MRSA activity and reduced toxicity. Bioorg. Med. Chem., 2007, 15, 6379- 7.
  • 121
    • 65649104960 scopus 로고    scopus 로고
    • Thye, D.A.; Kilfoilm, T.; Leighton, A. Doripenem: A phase 1 study to evaluate safety, tolerability and pharmacokinetics in a Western healthy volunteer population 43rd Intersci. Conf. Antimicrob. Agents Chemother., 2003, PA-21.
    • Thye, D.A.; Kilfoilm, T.; Leighton, A. Doripenem: A phase 1 study to evaluate safety, tolerability and pharmacokinetics in a Western healthy volunteer population 43rd Intersci. Conf. Antimicrob. Agents Chemother., 2003, PA-21.
  • 122
    • 0035170349 scopus 로고    scopus 로고
    • In vitro and in vivo antibacterial activities of L-084, a novel oral carbapenem, against causative organisms of respiratory tract infections
    • Miyazaki, S.; Hosoyama, T.; Furuya, N.; Ishii, Y.; Matsumoto, T.; Ohno, A.; Tateda, K.; and Yamaguchi, K. In vitro and in vivo antibacterial activities of L-084, a novel oral carbapenem, against causative organisms of respiratory tract infections. Antimicrob. Agents Chemother., 2001, 45, 203-7.
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 203-207
    • Miyazaki, S.1    Hosoyama, T.2    Furuya, N.3    Ishii, Y.4    Matsumoto, T.5    Ohno, A.6    Tateda, K.7    Yamaguchi, K.8
  • 123
    • 0032818533 scopus 로고    scopus 로고
    • In vitro antibacterial activity of LJC 11,036, an active metabolite of L-Bassetti 084, a new oral carbapenem antibiotic with potent antipneumococcal activity
    • Hikida, M.; Itahashi, K.; Igarashi, A.; Shiba, T.; Kitamura, M. In vitro antibacterial activity of LJC 11,036, an active metabolite of L-Bassetti 084, a new oral carbapenem antibiotic with potent antipneumococcal activity. Antimicrob. Agents Chemother., 1999, 43, 2010-6.
    • (1999) Antimicrob. Agents Chemother , vol.43 , pp. 2010-2016
    • Hikida, M.1    Itahashi, K.2    Igarashi, A.3    Shiba, T.4    Kitamura, M.5
  • 124
    • 14744268018 scopus 로고    scopus 로고
    • In vitro activity of tebipenem, a new oral carbapenem antibiotic, against penicillin-nonsusceptible Streptococcus pneumoniae
    • Kobayashi, R.; Konomi, M.; Hasegawa, K.; Morozumi, M.; Sunakawa, K.; Ubukata, K. In vitro activity of tebipenem, a new oral carbapenem antibiotic, against penicillin-nonsusceptible Streptococcus pneumoniae. Antimicrob. Agents Chemother., 2005, 49, 889-94
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 889-894
    • Kobayashi, R.1    Konomi, M.2    Hasegawa, K.3    Morozumi, M.4    Sunakawa, K.5    Ubukata, K.6
  • 127
    • 48749127049 scopus 로고    scopus 로고
    • Potent in vitro activity of tomopenem (CS-023) against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa
    • Koga, T.; Masuda, N.; Kakuta, M.; Namba, E.; Sugihara, C.; Fukuoka, T. Potent in vitro activity of tomopenem (CS-023) against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. Antimicrob. Agents Chemother., 2008, 52, 2849-54
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 2849-2854
    • Koga, T.1    Masuda, N.2    Kakuta, M.3    Namba, E.4    Sugihara, C.5    Fukuoka, T.6
  • 130
    • 3042683861 scopus 로고    scopus 로고
    • Treatment of polymicrobial infections: Post hoc analysis of three trials comparing ertapenem and piperacillin-tazobactam
    • Solomkin, J.; Teppler, H.; Graham, D.R.; Gesser, R.M.; Meibohm, A.R.; Roy, S.; Woods, G.L. Treatment of polymicrobial infections: Post hoc analysis of three trials comparing ertapenem and piperacillin-tazobactam. J. Antimicrob. Chemother., 2004, 53, 51-7.
    • (2004) J. Antimicrob. Chemother , vol.53 , pp. 51-57
    • Solomkin, J.1    Teppler, H.2    Graham, D.R.3    Gesser, R.M.4    Meibohm, A.R.5    Roy, S.6    Woods, G.L.7
  • 134
    • 3543061704 scopus 로고    scopus 로고
    • Doripenem (S-4661), a novel carbapenem: Comparative activity against contemporary pathogens including bactericidal action and preliminary in vitro methods evaluations
    • Jones, R.N.; Huynh, H.K.; Biedenbach, D.J.; Fritsche, T.R.; Sader, H.S. Doripenem (S-4661), a novel carbapenem: Comparative activity against contemporary pathogens including bactericidal action and preliminary in vitro methods evaluations. J. Antimicrob. Chemother., 2004, 54, 144-54.
    • (2004) J. Antimicrob. Chemother , vol.54 , pp. 144-154
    • Jones, R.N.1    Huynh, H.K.2    Biedenbach, D.J.3    Fritsche, T.R.4    Sader, H.S.5
  • 135
    • 1642502313 scopus 로고    scopus 로고
    • Comparative activities of doripenem versus isolates, mutants, and transconjugants of Enterobacteriaceae and Acinetobacter spp. with characterized betalactamases
    • Mushtaq, S.; Ge, Y.; Livermore, D.M. Comparative activities of doripenem versus isolates, mutants, and transconjugants of Enterobacteriaceae and Acinetobacter spp. with characterized betalactamases. Antimicrob. Agents Chemother., 2004, 48, 1313-9.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 1313-1319
    • Mushtaq, S.1    Ge, Y.2    Livermore, D.M.3
  • 137
    • 38649113256 scopus 로고    scopus 로고
    • In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds
    • Goldstein, E.J.; Citron, D.M.; Merriam, C.V.; Warren, Y.A.; Tyrrell, K.L.; Fernandez, H.T. In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. Antimicrob. Agents Chemother., 2008, 52, 761-6.
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 761-766
    • Goldstein, E.J.1    Citron, D.M.2    Merriam, C.V.3    Warren, Y.A.4    Tyrrell, K.L.5    Fernandez, H.T.6
  • 138
    • 31944435623 scopus 로고    scopus 로고
    • In vitro Activity of Doripenem against Pseudomonas aeruginosa and Burkholderia cepacia Isolates from both Cystic Fibrosis and Non-Cystic Fibrosis Patients
    • Traczewski, M.M.; Brown, S.D. In vitro Activity of Doripenem against Pseudomonas aeruginosa and Burkholderia cepacia Isolates from both Cystic Fibrosis and Non-Cystic Fibrosis Patients. Antimicrob. Agents Chemother., 2006, 50, 819-21.
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 819-821
    • Traczewski, M.M.1    Brown, S.D.2
  • 140
    • 0025366291 scopus 로고
    • Biochemical characterization of a beta-lactamase that hydrolyzes penems and carbapenems from two Serratia marcescens isolates
    • Yang, Y.; Wu, P.; Livermore, D.M. Biochemical characterization of a beta-lactamase that hydrolyzes penems and carbapenems from two Serratia marcescens isolates. Antimicrob. Agents Chemother., 1990, 34, 755-58.
    • (1990) Antimicrob. Agents Chemother , vol.34 , pp. 755-758
    • Yang, Y.1    Wu, P.2    Livermore, D.M.3
  • 142
    • 65649127053 scopus 로고    scopus 로고
    • 26th Intersci. Conf. Antimicrob. Agents Chemother
    • PA-116
    • Medeiros, A.A.; Hare, R.S. Beta-Lactamase-mediated resistance to penems and carbapenems amongst Enterobacteriaceae. 26th Intersci. Conf. Antimicrob. Agents Chemother., 1996, PA-116.
    • (1996)
    • Medeiros, A.A.1    Hare, R.S.2
  • 144
    • 0033998662 scopus 로고    scopus 로고
    • Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae
    • Poirel, L.; Le Thomas, I.; Naas, T.; Karim, A.; Nordmann, P. Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae. Antimicrob. Agents Chemother., 2000, 44, 622-32.
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 622-632
    • Poirel, L.1    Le Thomas, I.2    Naas, T.3    Karim, A.4    Nordmann, P.5
  • 145
    • 27544501067 scopus 로고    scopus 로고
    • The emergence and implications of metallo-betalactamases in Gram-negative bacteria
    • Walsh, T.R. The emergence and implications of metallo-betalactamases in Gram-negative bacteria Clin. Microbiol. Infect., 2005, 11, 2-9.
    • (2005) Clin. Microbiol. Infect , vol.11 , pp. 2-9
    • Walsh, T.R.1
  • 146
    • 17444363393 scopus 로고    scopus 로고
    • Walsh, T.R.; Toleman, M.A.; Poirel, L.; Nordmann, P. Metallobeta-lactamases: The quiet before the storm? Clin. Microbiol. Rev., 2005, 18, 306-325.
    • Walsh, T.R.; Toleman, M.A.; Poirel, L.; Nordmann, P. Metallobeta-lactamases: The quiet before the storm? Clin. Microbiol. Rev., 2005, 18, 306-325.
  • 147
    • 0023947386 scopus 로고
    • Cloning, nucleotide sequence, and expression of the Bacillus cereus 5/B/6 β-lactamase II structural gene
    • Lim, H.M.; Pene, J.J., Shaw, R.W. Cloning, nucleotide sequence, and expression of the Bacillus cereus 5/B/6 β-lactamase II structural gene. J. Bacteriol., 1988, 170, 2873-78.
    • (1988) J. Bacteriol , vol.170 , pp. 2873-2878
    • Lim, H.M.1    Pene, J.J.2    Shaw, R.W.3
  • 148
    • 0031973490 scopus 로고    scopus 로고
    • Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases
    • Massova, I.; Mobashery S. Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases. Antimicrob. Agents Chemother., 1998, 42, 1-17.
    • (1998) Antimicrob. Agents Chemother , vol.42 , pp. 1-17
    • Massova, I.1    Mobashery, S.2
  • 149
    • 27644562636 scopus 로고    scopus 로고
    • Novel acquired metallo-β-lactamase gene, blaSIM-1, in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea
    • Lee, K.; Yum J.H.; Yong D.; Lee, H.M.; Kim H.D.; Docquier J.D.; Rossolini, G.M.; Chong Y. Novel acquired metallo-β-lactamase gene, blaSIM-1, in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea Antimicrob. Agents Chemother., 2005, 49, 4485-91.
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 4485-4491
    • Lee, K.1    Yum, J.H.2    Yong, D.3    Lee, H.M.4    Kim, H.D.5    Docquier, J.D.6    Rossolini, G.M.7    Chong, Y.8
  • 151
    • 33747192635 scopus 로고    scopus 로고
    • Identification of Acinetobacter baumannii by detection of the blaOXA-51-like carbapenemase gene intrinsic to this species
    • Turton, J.F.; Woodford, N.; Glover, J.; Yarde, S.; Kaufmann, M.E.; Pitt, T.L. Identification of Acinetobacter baumannii by detection of the blaOXA-51-like carbapenemase gene intrinsic to this species. J. Clin. Microbiol., 2006, 44, 2974-6.
    • (2006) J. Clin. Microbiol , vol.44 , pp. 2974-2976
    • Turton, J.F.1    Woodford, N.2    Glover, J.3    Yarde, S.4    Kaufmann, M.E.5    Pitt, T.L.6
  • 152
    • 33845246106 scopus 로고    scopus 로고
    • Pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem, in healthy male Caucasian volunteers
    • Shibayama, T.; Matsushita, Y.; Hirota, T.; Ikeda, T.; Kuwaharam, S. Pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem, in healthy male Caucasian volunteers. Antimicrob. Agents Chemother., 2006, 50, 4186-8.
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 4186-4188
    • Shibayama, T.1    Matsushita, Y.2    Hirota, T.3    Ikeda, T.4    Kuwaharam, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.