Unsymmetric aryl-alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracis

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 13, 2008, Pages 6501-6508

  Turos, Edward ^a   Revell, Kevin D ^b   Ramaraju, Praveen ^a   Gergeres, Danielle A ^a   Greenhalgh, Kerriann ^a   Young, Ashley ^a   Sathyanarayan, Nalini ^b   Dickey, Sonja ^a   Lim, Daniel ^a   Alhamadsheh, Mamoun M ^c   Reynolds, Kevin ^c  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b MURRAY STATE UNIVERSITY   (United States)

^c PORTLAND STATE UNIVERSITY   (United States)

Author keywords

Bacillus anthracis; Disulfides; FabH protein; Lipid biosynthesis; MRSA

Indexed keywords

2 (HYDROXYMETHYL)PHENYLMETHYL DISULFIDE; 3 ETHOXYPHENYLMETHYL DISULFIDE; 3,4 DIFLUOROPHENYLMETHYL DISULFIDE; 3,4 DIMETHYLPHENYLMETHYL DISULFIDE; 4 ACETAMIDOPHENYLMETHYL DISULFIDE; 4 AMINOPHENYLMETHYL DISULFIDE; 4 NITROPHENYL PROPYL DISULFIDE; 4 NITROPHENYLMETHYL DISULFIDE; ANTIBIOTIC AGENT; BUTYL 2 NITROPHENYL DISULFIDE; BUTYL 3 NITROPHENYL DISULFIDE; BUTYL 4 NITROPHENYL DISULFIDE; DISULFIDE; ETHYL 2 NITROPHENYL DISULFIDE; ETHYL 3 NITROPHENYL DISULFIDE; ETHYL 4 NITROPHENYL DISULFIDE; ISOPROPYL 2 NITROPHENYL DISULFIDE; ISOPROPYL 3 NITROPHENYL DISULFIDE; ISOPROPYL 4 NITROPHENYL DISULFIDE; METHYL 2 (4 NITROPHENETHYL)DISULFIDE; METHYL 2 NITROPHENYL DISULFIDE; METHYL 2 PYRIDINYL DISULFIDE; METHYL 3 NITROPHENYL DISULFIDE; METHYL 4 NITROBENZYL DISULFIDE; PENICILLIN G; SEC BUTYL 4 NITROPHENYL DISULFIDE; VANCOMYCIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL GROWTH; BACTERIAL MEMBRANE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOPLASM; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; FATTY ACID SYNTHESIS; GROWTH INHIBITION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

ALKYLATION; BACILLUS ANTHRACIS; DISULFIDES; METHICILLIN RESISTANCE; METHYLATION; MICROBIAL VIABILITY; MOLECULAR STRUCTURE; STAPHYLOCOCCUS AUREUS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 44949097209     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.05.032     Document Type: Article

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