TRPV1 antagonists as potential antitussive agents

Lung

Volumn 186, Issue SUPPL. 1, 2008, Pages

  McLeod, Robbie L ^a   Correll, Craig C ^a   Jia, Yanlin ^a   Anthes, John C ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Antitussive; C fiber; Capsaicin; TRPV1; Vanilloid

Indexed keywords

1 (2 BROMOPHENYL) 3 [1 (5 TRIFLUOROMETHYL 2 PYRIDINYL) 3 PYRROLIDINYL]UREA; AMG 517; AMG 628; ANTITUSSIVE AGENT; CAPSAICIN; GRC 6211; N (4 TERTBUTYLPHENYL) 4 (3 CHLORPHYRIDIN 2 YL)TETRAHYDROPYRAZINE 1(2H) CARBOXYAMIDE; NGD 8243; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST;

CLINICAL TRIAL; CONFERENCE PAPER; COUGHING; GUINEA PIG; HUMAN; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; UPPER RESPIRATORY TRACT INFECTION;

ANIMALS; ANTITUSSIVE AGENTS; CAPSAICIN; COUGH; HUMANS; LUNG; REFLEX; SENSORY SYSTEM AGENTS; TREATMENT OUTCOME; TRPV CATION CHANNELS;

EID: 40149088458     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00408-007-9032-z     Document Type: Conference Paper

References (66)