Antithrombotic and hemostatic effects of a small molecule factor XIa inhibitor in rats

European Journal of Pharmacology

Volumn 570, Issue 1-3, 2007, Pages 167-174

  Schumacher, William A ^a   Seiler, Steven E ^a   Steinbacher, Thomas E ^a   Stewart, Anne B ^a   Bostwick, Jeffrey S ^a   Hartl, Karen S ^a   Liu, Eddie C ^a   Ogletree, Martin L ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Anticoagulant; Bleeding time; Blood coagulation; Factor XIa; Hemostasis; Thrombosis

Indexed keywords

BLOOD CLOTTING INHIBITOR; BMS 262084; FERROUS CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ARTICLE; BLEEDING TIME; BLOOD CLOTTING PARAMETERS; CAROTID ARTERY THROMBOSIS; CAVA VEIN OBSTRUCTION; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; EX VIVO STUDY; HEMOSTASIS; IC 50; IN VITRO STUDY; KIDNEY CORTEX; LOADING DRUG DOSE; MALE; MESENTERY BLOOD VESSEL; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL ANALYSIS; THROMBOGENESIS; THROMBOPLASTIN TIME; VEIN PUNCTURE;

ANIMALS; AZETIDINES; CAROTID ARTERY THROMBOSIS; FACTOR XIA; FIBRINOLYTIC AGENTS; HEMOSTATICS; HUMANS; MALE; PARTIAL THROMBOPLASTIN TIME; PIPERAZINES; PROTHROMBIN TIME; RATS; RATS, SPRAGUE-DAWLEY; TRYPTASES; VENOUS THROMBOSIS;

EID: 34547828204     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.05.043     Document Type: Article

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