Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 9, 2004, Pages 2227-2231

  Bisacchi, Gregory S ^a   Slusarchyk, William A ^a   Bolton, Scott A ^a   Hartl, Karen S ^a   Jacobs, Glenn ^a   Mathur, Arvind ^a   Meng, Wei ^a   Ogletree, Martin L ^a   Pi, Zulan ^a   Sutton, James C ^a   Treuner, Uwe ^a   Zahler, Robert ^a   Zhao, Guohua ^a   Seiler, Steven M ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BMS 354326; SERINE PROTEINASE; TRYPSIN; TRYPTASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; IC 50; INHIBITION KINETICS; SUBSTITUTION REACTION;

AZETIDINES; HUMANS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; TRYPTASES;

EID: 11144355065     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.011     Document Type: Article

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