Novel N-thiolated β-lactam antibiotics selectively induce apoptosis in human tumor and transformed, but not normal or nontransformed, cells

Biochemical Pharmacology

Volumn 67, Issue 2, 2004, Pages 365-374

  Kazi, Aslamuzzaman ^a   Hill, Randy ^a   Long, Timothy E ^b   Kuhn, Deborah J ^a   Turos, Edward ^a,b   Dou, Q Ping ^a,c  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antibiotics; Anticancer drugs; Apoptosis; DNA damage; N thiolated lactam

Indexed keywords

BETA LACTAM ANTIBIOTIC;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CELL IMMORTALIZATION; COLONY FORMING CELL; CONTROLLED STUDY; DNA DAMAGE; DRUG ACTIVITY; DRUG POTENCY; FIBROBLAST; HEAD CANCER; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; NATURAL KILLER CELL; NECK CANCER; PRIORITY JOURNAL; PROSTATE CANCER; SIMIAN VIRUS 40; STRUCTURE ACTIVITY RELATION;

EID: 1642579531     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2003.09.017     Document Type: Article

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