-
1
-
-
77956217755
-
A review of complementary and alternative medicine practices among cancer survivors
-
10.1188/10.CJON.365-370, 20529798
-
Bell RM. A review of complementary and alternative medicine practices among cancer survivors. Clin J Oncol Nurs 2010, 14:365-370. 10.1188/10.CJON.365-370, 20529798.
-
(2010)
Clin J Oncol Nurs
, vol.14
, pp. 365-370
-
-
Bell, R.M.1
-
2
-
-
0042844744
-
Natural products as sources of new drugs over the period 1981-2002
-
10.1021/np030096l, 12880330
-
Newman DJ, Cragg GM, Snader KM. Natural products as sources of new drugs over the period 1981-2002. J Nat Prod 2003, 66:1022-1037. 10.1021/np030096l, 12880330.
-
(2003)
J Nat Prod
, vol.66
, pp. 1022-1037
-
-
Newman, D.J.1
Cragg, G.M.2
Snader, K.M.3
-
3
-
-
34047249406
-
Anti-inflammatory, analgesic and antipyretic activities of the extract of gamboge from Garcinia hanburyi Hook f
-
10.1016/j.jep.2006.11.038, 17360136
-
Panthong A, Norkaew P, Kanjanapothi D, Taesotikul T, Anantachoke N, Reutrakul V. Anti-inflammatory, analgesic and antipyretic activities of the extract of gamboge from Garcinia hanburyi Hook f. J Ethnopharmacol 2007, 111:335-340. 10.1016/j.jep.2006.11.038, 17360136.
-
(2007)
J Ethnopharmacol
, vol.111
, pp. 335-340
-
-
Panthong, A.1
Norkaew, P.2
Kanjanapothi, D.3
Taesotikul, T.4
Anantachoke, N.5
Reutrakul, V.6
-
4
-
-
24744435348
-
A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid
-
10.1073/pnas.0406731102, 1189297, 16103367
-
Kasibhatla S, Jessen KA, Maliartchouk S, Wang JY, English NM, Drewe J, Qiu L, Archer SP, Ponce AE, Sirisoma N, Jiang S, Zhang HZ, Gehlsen KR, Cai SX, Green DR, Tseng B. A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid. Proc Natl Acad Sci USA 2005, 102:12095-12100. 10.1073/pnas.0406731102, 1189297, 16103367.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12095-12100
-
-
Kasibhatla, S.1
Jessen, K.A.2
Maliartchouk, S.3
Wang, J.Y.4
English, N.M.5
Drewe, J.6
Qiu, L.7
Archer, S.P.8
Ponce, A.E.9
Sirisoma, N.10
Jiang, S.11
Zhang, H.Z.12
Gehlsen, K.R.13
Cai, S.X.14
Green, D.R.15
Tseng, B.16
-
5
-
-
55749086025
-
Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells
-
10.1158/1535-7163.MCT-08-0212, 18852133
-
Gu H, Wang X, Rao S, Wang J, Zhao J, Ren FL, Mu R, Yang Y, Qi Q, Liu W, Lu N, Ling H, You Q, Guo Q. Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells. Mol Cancer Ther 2008, 7:3298-3305. 10.1158/1535-7163.MCT-08-0212, 18852133.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3298-3305
-
-
Gu, H.1
Wang, X.2
Rao, S.3
Wang, J.4
Zhao, J.5
Ren, F.L.6
Mu, R.7
Yang, Y.8
Qi, Q.9
Liu, W.10
Lu, N.11
Ling, H.12
You, Q.13
Guo, Q.14
-
6
-
-
20344405555
-
Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells
-
10.1248/bpb.27.1769, 15516720
-
Wu ZQ, Guo QL, You QD, Zhao L, Gu HY. Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells. Biol Pharm Bull 2004, 27:1769-1774. 10.1248/bpb.27.1769, 15516720.
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 1769-1774
-
-
Wu, Z.Q.1
Guo, Q.L.2
You, Q.D.3
Zhao, L.4
Gu, H.Y.5
-
7
-
-
38949176773
-
Inhibition of glioblastoma growth and angiogenesis by gambogic acid: an in vitro and in vivo study
-
10.1016/j.bcp.2007.10.033, 18070617
-
Qiang L, Yang Y, You QD, Ma YJ, Yang L, Nie FF, Gu HY, Zhao L, Lu N, Qi Q, Liu W, Wang XT, Guo QL. Inhibition of glioblastoma growth and angiogenesis by gambogic acid: an in vitro and in vivo study. Biochem Pharmacol 2008, 75:1083-1092. 10.1016/j.bcp.2007.10.033, 18070617.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1083-1092
-
-
Qiang, L.1
Yang, Y.2
You, Q.D.3
Ma, Y.J.4
Yang, L.5
Nie, F.F.6
Gu, H.Y.7
Zhao, L.8
Lu, N.9
Qi, Q.10
Liu, W.11
Wang, X.T.12
Guo, Q.L.13
-
8
-
-
56949096780
-
Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis
-
10.1007/s00109-008-0398-z, 18777017
-
Qi Q, Gu H, Yang Y, Lu N, Zhao J, Liu W, Ling H, You QD, Wang X, Guo Q. Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis. J Mol Med 2008, 86:1367-1377. 10.1007/s00109-008-0398-z, 18777017.
-
(2008)
J Mol Med
, vol.86
, pp. 1367-1377
-
-
Qi, Q.1
Gu, H.2
Yang, Y.3
Lu, N.4
Zhao, J.5
Liu, W.6
Ling, H.7
You, Q.D.8
Wang, X.9
Guo, Q.10
-
9
-
-
60349092524
-
Proteomic identification of molecular targets of gambogic acid: role of stathmin in hepatocellular carcinoma
-
10.1002/pmic.200800155, 19086098
-
Wang X, Chen Y, Han QB, Chan CY, Wang H, Liu Z, Cheng CH, Yew DT, Lin MC, He ML, Xu HX, Sung JJ, Kung HF. Proteomic identification of molecular targets of gambogic acid: role of stathmin in hepatocellular carcinoma. Proteomics 2009, 9:242-253. 10.1002/pmic.200800155, 19086098.
-
(2009)
Proteomics
, vol.9
, pp. 242-253
-
-
Wang, X.1
Chen, Y.2
Han, Q.B.3
Chan, C.Y.4
Wang, H.5
Liu, Z.6
Cheng, C.H.7
Yew, D.T.8
Lin, M.C.9
He, M.L.10
Xu, H.X.11
Sung, J.J.12
Kung, H.F.13
-
10
-
-
69049088724
-
Gambogic acid down-regulates MDM2 oncogene and induces p21(Waf1/CIP1) expression independent of p53
-
10.1016/j.canlet.2009.04.011, 19428175
-
Rong JJ, Hu R, Qi Q, Gu HY, Zhao Q, Wang J, Mu R, You QD, Guo QL. Gambogic acid down-regulates MDM2 oncogene and induces p21(Waf1/CIP1) expression independent of p53. Cancer Lett 2009, 284:102-112. 10.1016/j.canlet.2009.04.011, 19428175.
-
(2009)
Cancer Lett
, vol.284
, pp. 102-112
-
-
Rong, J.J.1
Hu, R.2
Qi, Q.3
Gu, H.Y.4
Zhao, Q.5
Wang, J.6
Mu, R.7
You, Q.D.8
Guo, Q.L.9
-
11
-
-
49849094579
-
Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins
-
10.1158/1535-7163.MCT-07-2373, 2614397, 18566235
-
Zhai D, Jin C, Shiau CW, Kitada S, Satterthwait AC, Reed JC. Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins. Mol Cancer Ther 2008, 7:1639-1646. 10.1158/1535-7163.MCT-07-2373, 2614397, 18566235.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1639-1646
-
-
Zhai, D.1
Jin, C.2
Shiau, C.W.3
Kitada, S.4
Satterthwait, A.C.5
Reed, J.C.6
-
12
-
-
35349029248
-
Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway
-
10.1182/blood-2007-03-079616, 2077305, 17673602
-
Pandey MK, Sung B, Ahn KS, Kunnumakkara AB, Chaturvedi MM, Aggarwal BB. Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway. Blood 2007, 110:3517-3525. 10.1182/blood-2007-03-079616, 2077305, 17673602.
-
(2007)
Blood
, vol.110
, pp. 3517-3525
-
-
Pandey, M.K.1
Sung, B.2
Ahn, K.S.3
Kunnumakkara, A.B.4
Chaturvedi, M.M.5
Aggarwal, B.B.6
-
13
-
-
34748925888
-
Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain
-
10.1158/1535-7163.MCT-07-0147, 17876042
-
Qin Y, Meng L, Hu C, Duan W, Zuo Z, Lin L, Zhang X, Ding J. Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain. Mol Cancer Ther 2007, 6:2429-2440. 10.1158/1535-7163.MCT-07-0147, 17876042.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2429-2440
-
-
Qin, Y.1
Meng, L.2
Hu, C.3
Duan, W.4
Zuo, Z.5
Lin, L.6
Zhang, X.7
Ding, J.8
-
14
-
-
47549099788
-
Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid
-
10.1016/j.ejphar.2008.04.063, 18539272
-
Zhao J, Qi Q, Yang Y, Gu HY, Lu N, Liu W, Wang W, Qiang L, Zhang LB, You QD, Guo QL. Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid. Eur J Pharmacol 2008, 589:127-131. 10.1016/j.ejphar.2008.04.063, 18539272.
-
(2008)
Eur J Pharmacol
, vol.589
, pp. 127-131
-
-
Zhao, J.1
Qi, Q.2
Yang, Y.3
Gu, H.Y.4
Lu, N.5
Liu, W.6
Wang, W.7
Qiang, L.8
Zhang, L.B.9
You, Q.D.10
Guo, Q.L.11
-
15
-
-
70449412700
-
The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma
-
10.1186/1471-2407-9-343, 2760578, 19778460
-
He D, Xu Q, Yan M, Zhang P, Zhou X, Zhang Z, Duan W, Zhong L, Ye D, Chen W. The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma. BMC Cancer 2009, 9:343. 10.1186/1471-2407-9-343, 2760578, 19778460.
-
(2009)
BMC Cancer
, vol.9
, pp. 343
-
-
He, D.1
Xu, Q.2
Yan, M.3
Zhang, P.4
Zhou, X.5
Zhang, Z.6
Duan, W.7
Zhong, L.8
Ye, D.9
Chen, W.10
-
16
-
-
58149218002
-
Synergistic effect of 5-fluorouracil with gambogic acid on BGC-823 human gastric carcinoma
-
10.1016/j.tox.2008.11.014, 19084572
-
Wang J, Liu W, Zhao Q, Qi Q, Lu N, Yang Y, Nei FF, Rong JJ, You QD, Guo QL. Synergistic effect of 5-fluorouracil with gambogic acid on BGC-823 human gastric carcinoma. Toxicology 2009, 256:135-140. 10.1016/j.tox.2008.11.014, 19084572.
-
(2009)
Toxicology
, vol.256
, pp. 135-140
-
-
Wang, J.1
Liu, W.2
Zhao, Q.3
Qi, Q.4
Lu, N.5
Yang, Y.6
Nei, F.F.7
Rong, J.J.8
You, Q.D.9
Guo, Q.L.10
-
17
-
-
40849094400
-
Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells
-
10.1016/j.canlet.2007.12.004, 18248784
-
Wang T, Wei J, Qian X, Ding Y, Yu L, Liu B. Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells. Cancer Lett 2008, 262:214-222. 10.1016/j.canlet.2007.12.004, 18248784.
-
(2008)
Cancer Lett
, vol.262
, pp. 214-222
-
-
Wang, T.1
Wei, J.2
Qian, X.3
Ding, Y.4
Yu, L.5
Liu, B.6
-
18
-
-
77449115138
-
Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells
-
2789437, 20011242
-
Chen B, Liang Y, Wu W, Cheng J, Xia G, Gao F, Ding J, Gao C, Shao Z, Li G, Chen W, Xu W, Sun X, Liu L, Li X, Wang X. Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells. Int J Nanomedicine 2009, 4:251-259. 2789437, 20011242.
-
(2009)
Int J Nanomedicine
, vol.4
, pp. 251-259
-
-
Chen, B.1
Liang, Y.2
Wu, W.3
Cheng, J.4
Xia, G.5
Gao, F.6
Ding, J.7
Gao, C.8
Shao, Z.9
Li, G.10
Chen, W.11
Xu, W.12
Sun, X.13
Liu, L.14
Li, X.15
Wang, X.16
-
19
-
-
57049126496
-
Identification of Curcuma plants and curcumin content level by DNA polymorphisms in the trnS-trnfM intergenic spacer in chloroplast DNA
-
10.1007/s11418-008-0283-7, 18688695
-
Minami M, Nishio K, Ajioka Y, Kyushima H, Shigeki K, Kinjo K, Yamada K, Nagai M, Satoh K, Sakurai Y. Identification of Curcuma plants and curcumin content level by DNA polymorphisms in the trnS-trnfM intergenic spacer in chloroplast DNA. J Nat Med 2009, 63:75-79. 10.1007/s11418-008-0283-7, 18688695.
-
(2009)
J Nat Med
, vol.63
, pp. 75-79
-
-
Minami, M.1
Nishio, K.2
Ajioka, Y.3
Kyushima, H.4
Shigeki, K.5
Kinjo, K.6
Yamada, K.7
Nagai, M.8
Satoh, K.9
Sakurai, Y.10
-
20
-
-
38749109673
-
Curcumin as "Curecumin": from kitchen to clinic
-
10.1016/j.bcp.2007.08.016, 17900536
-
Goel A, Kunnumakkara AB, Aggarwal BB. Curcumin as "Curecumin": from kitchen to clinic. Biochem Pharmacol 2008, 75:787-809. 10.1016/j.bcp.2007.08.016, 17900536.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 787-809
-
-
Goel, A.1
Kunnumakkara, A.B.2
Aggarwal, B.B.3
-
21
-
-
53449094405
-
Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent
-
Lopez-Lazaro M. Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent. Mol Nutr Food Res 2008, 52(Suppl 1):S103-127.
-
(2008)
Mol Nutr Food Res
, vol.52
, Issue.SUPPL. 1
-
-
Lopez-Lazaro, M.1
-
22
-
-
84934438047
-
Curcumin as an inhibitor of angiogenesis
-
10.1007/978-0-387-46401-5_7, 17569211
-
Bhandarkar SS, Arbiser JL. Curcumin as an inhibitor of angiogenesis. Adv Exp Med Biol 2007, 595:185-195. 10.1007/978-0-387-46401-5_7, 17569211.
-
(2007)
Adv Exp Med Biol
, vol.595
, pp. 185-195
-
-
Bhandarkar, S.S.1
Arbiser, J.L.2
-
23
-
-
73349094986
-
Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?
-
10.1208/s12248-009-9128-x, 2758121, 19590964
-
Ravindran J, Prasad S, Aggarwal BB. Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?. AAPS J 2009, 11:495-510. 10.1208/s12248-009-9128-x, 2758121, 19590964.
-
(2009)
AAPS J
, vol.11
, pp. 495-510
-
-
Ravindran, J.1
Prasad, S.2
Aggarwal, B.B.3
-
24
-
-
27144468987
-
Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice
-
10.1158/1078-0432.CCR-05-1192, 16243823
-
Aggarwal BB, Shishodia S, Takada Y, Banerjee S, Newman RA, Bueso-Ramos CE, Price JE. Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice. Clin Cancer Res 2005, 11:7490-7498. 10.1158/1078-0432.CCR-05-1192, 16243823.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7490-7498
-
-
Aggarwal, B.B.1
Shishodia, S.2
Takada, Y.3
Banerjee, S.4
Newman, R.A.5
Bueso-Ramos, C.E.6
Price, J.E.7
-
25
-
-
54349091392
-
Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition
-
10.1136/gut.2008.152496, 2582343, 18596194
-
Binion DG, Otterson MF, Rafiee P. Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition. Gut 2008, 57:1509-1517. 10.1136/gut.2008.152496, 2582343, 18596194.
-
(2008)
Gut
, vol.57
, pp. 1509-1517
-
-
Binion, D.G.1
Otterson, M.F.2
Rafiee, P.3
-
26
-
-
35848938724
-
Roles of the Akt/mTOR/p70S6K and ERK1/2 signaling pathways in curcumin- induced autophagy
-
Shinojima N, Yokoyama T, Kondo Y, Kondo S. Roles of the Akt/mTOR/p70S6K and ERK1/2 signaling pathways in curcumin- induced autophagy. Autophagy 2007, 3:635-637.
-
(2007)
Autophagy
, vol.3
, pp. 635-637
-
-
Shinojima, N.1
Yokoyama, T.2
Kondo, Y.3
Kondo, S.4
-
27
-
-
34347238938
-
Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways
-
10.1124/mol.106.033167, 17395690
-
Aoki H, Takada Y, Kondo S, Sawaya R, Aggarwal BB, Kondo Y. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. Mol Pharmacol 2007, 72:29-39. 10.1124/mol.106.033167, 17395690.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 29-39
-
-
Aoki, H.1
Takada, Y.2
Kondo, S.3
Sawaya, R.4
Aggarwal, B.B.5
Kondo, Y.6
-
28
-
-
77949595310
-
Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells
-
10.1080/10286020903264077, 20183254
-
Jia YL, Li J, Qin ZH, Liang ZQ. Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells. J Asian Nat Prod Res 2009, 11:918-928. 10.1080/10286020903264077, 20183254.
-
(2009)
J Asian Nat Prod Res
, vol.11
, pp. 918-928
-
-
Jia, Y.L.1
Li, J.2
Qin, Z.H.3
Liang, Z.Q.4
-
29
-
-
75149124278
-
Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells
-
Yoon MJ, Kim EH, Lim JH, Kwon TK, Choi KS. Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells. Free Radic Biol Med 2009, 48:713-726.
-
(2009)
Free Radic Biol Med
, vol.48
, pp. 713-726
-
-
Yoon, M.J.1
Kim, E.H.2
Lim, J.H.3
Kwon, T.K.4
Choi, K.S.5
-
30
-
-
78650624633
-
Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells
-
10.1002/ijc.25410, 20473900
-
Nautiyal J, Banerjee S, Kanwar SS, Yu Y, Patel BB, Sarkar FH, Majumdar AP. Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells. Int J Cancer 2011, 128:951-961. 10.1002/ijc.25410, 20473900.
-
(2011)
Int J Cancer
, vol.128
, pp. 951-961
-
-
Nautiyal, J.1
Banerjee, S.2
Kanwar, S.S.3
Yu, Y.4
Patel, B.B.5
Sarkar, F.H.6
Majumdar, A.P.7
-
31
-
-
34547455906
-
Protective effect of curcumin and chlorophyllin against DNA mutation induced by cyclophosphamide or benzo[a]pyrene
-
Ibrahim MA, Elbehairy AM, Ghoneim MA, Amer HA. Protective effect of curcumin and chlorophyllin against DNA mutation induced by cyclophosphamide or benzo[a]pyrene. Z Naturforsch C 2007, 62:215-222.
-
(2007)
Z Naturforsch C
, vol.62
, pp. 215-222
-
-
Ibrahim, M.A.1
Elbehairy, A.M.2
Ghoneim, M.A.3
Amer, H.A.4
-
32
-
-
64549130896
-
Uroprotective effects of curcumin in cyclophosphamide -induced haemorrhagic cystitis paradigm
-
10.1111/j.1742-7843.2009.00379.x, 19413659
-
Arafa HM. Uroprotective effects of curcumin in cyclophosphamide -induced haemorrhagic cystitis paradigm. Basic Clin Pharmacol Toxicol 2009, 104:393-399. 10.1111/j.1742-7843.2009.00379.x, 19413659.
-
(2009)
Basic Clin Pharmacol Toxicol
, vol.104
, pp. 393-399
-
-
Arafa, H.M.1
-
33
-
-
0028955691
-
Modulation of cyclophosphamide-induced early lung injury by curcumin, an anti-inflammatory antioxidant
-
10.1007/BF00928916, 7753045
-
Venkatesan N, Chandrakasan G. Modulation of cyclophosphamide-induced early lung injury by curcumin, an anti-inflammatory antioxidant. Mol Cell Biochem 1995, 142:79-87. 10.1007/BF00928916, 7753045.
-
(1995)
Mol Cell Biochem
, vol.142
, pp. 79-87
-
-
Venkatesan, N.1
Chandrakasan, G.2
-
34
-
-
77955514247
-
Assessment of cell viability, lipid peroxidation and quantification of DNA fragmentation after the treatment of anticancerous drug mitomycin C and curcumin in cultured human blood lymphocytes
-
10.1016/j.etp.2009.06.010, 19608391
-
Siddique YH, Ara G, Beg T, Gupta J, Afzal M. Assessment of cell viability, lipid peroxidation and quantification of DNA fragmentation after the treatment of anticancerous drug mitomycin C and curcumin in cultured human blood lymphocytes. Exp Toxicol Pathol 2010, 62:503-508. 10.1016/j.etp.2009.06.010, 19608391.
-
(2010)
Exp Toxicol Pathol
, vol.62
, pp. 503-508
-
-
Siddique, Y.H.1
Ara, G.2
Beg, T.3
Gupta, J.4
Afzal, M.5
-
35
-
-
71049152019
-
Curcumin reduced the side effects of mitomycin C by inhibiting GRP58-mediated DNA cross-linking in MCF-7 breast cancer xenografts
-
10.1111/j.1349-7006.2009.01297.x, 19703194
-
Zhou QM, Zhang H, Lu YY, Wang XF, Su SB. Curcumin reduced the side effects of mitomycin C by inhibiting GRP58-mediated DNA cross-linking in MCF-7 breast cancer xenografts. Cancer Sci 2009, 100:2040-2045. 10.1111/j.1349-7006.2009.01297.x, 19703194.
-
(2009)
Cancer Sci
, vol.100
, pp. 2040-2045
-
-
Zhou, Q.M.1
Zhang, H.2
Lu, Y.Y.3
Wang, X.F.4
Su, S.B.5
-
36
-
-
79960936657
-
Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo
-
Howells LM, Sale S, Sriramareddy SN, Irving GR, Jones DJ, Ottley CJ, Pearson DG, Mann CD, Manson MM, Berry DP, Gescher A, Steward WP, Brown K. Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo. Int J Cancer 2010,
-
(2010)
Int J Cancer
-
-
Howells, L.M.1
Sale, S.2
Sriramareddy, S.N.3
Irving, G.R.4
Jones, D.J.5
Ottley, C.J.6
Pearson, D.G.7
Mann, C.D.8
Manson, M.M.9
Berry, D.P.10
Gescher, A.11
Steward, W.P.12
Brown, K.13
-
37
-
-
77958011209
-
Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs
-
10.1080/01635581.2010.509835, 20924967
-
Goel A, Aggarwal BB. Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs. Nutr Cancer 2010, 62:919-930. 10.1080/01635581.2010.509835, 20924967.
-
(2010)
Nutr Cancer
, vol.62
, pp. 919-930
-
-
Goel, A.1
Aggarwal, B.B.2
-
38
-
-
77953406082
-
Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth
-
10.1186/1757-2215-3-11, 2880315, 20429876
-
Yallapu MM, Maher DM, Sundram V, Bell MC, Jaggi M, Chauhan SC. Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth. J Ovarian Res 2010, 3:11. 10.1186/1757-2215-3-11, 2880315, 20429876.
-
(2010)
J Ovarian Res
, vol.3
, pp. 11
-
-
Yallapu, M.M.1
Maher, D.M.2
Sundram, V.3
Bell, M.C.4
Jaggi, M.5
Chauhan, S.C.6
-
39
-
-
44749093175
-
Curcumin: from ancient medicine to current clinical trials
-
10.1007/s00018-008-7452-4, 18324353
-
Hatcher H, Planalp R, Cho J, Torti FM, Torti SV. Curcumin: from ancient medicine to current clinical trials. Cell Mol Life Sci 2008, 65:1631-1652. 10.1007/s00018-008-7452-4, 18324353.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1631-1652
-
-
Hatcher, H.1
Planalp, R.2
Cho, J.3
Torti, F.M.4
Torti, S.V.5
-
40
-
-
77954160638
-
Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer
-
Bayet-Robert M, Kwiatkowski F, Leheurteur M, Gachon F, Planchat E, Abrial C, Mouret-Reynier MA, Durando X, Barthomeuf C, Chollet P. Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer. Cancer Biol Ther 2009, 9:8-14.
-
(2009)
Cancer Biol Ther
, vol.9
, pp. 8-14
-
-
Bayet-Robert, M.1
Kwiatkowski, F.2
Leheurteur, M.3
Gachon, F.4
Planchat, E.5
Abrial, C.6
Mouret-Reynier, M.A.7
Durando, X.8
Barthomeuf, C.9
Chollet, P.10
-
41
-
-
79959612772
-
A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer
-
10.1007/s00280-010-1470-2, 20859741
-
Kanai M, Yoshimura K, Asada M, Imaizumi A, Suzuki C, Matsumoto S, Nishimura T, Mori Y, Masui T, Kawaguchi Y, Yanagihara K, Yazumi S, Chiba T, Guha S, Aggarwal BB. A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer. Cancer Chemother Pharmacol 2011, 68:157-164. 10.1007/s00280-010-1470-2, 20859741.
-
(2011)
Cancer Chemother Pharmacol
, vol.68
, pp. 157-164
-
-
Kanai, M.1
Yoshimura, K.2
Asada, M.3
Imaizumi, A.4
Suzuki, C.5
Matsumoto, S.6
Nishimura, T.7
Mori, Y.8
Masui, T.9
Kawaguchi, Y.10
Yanagihara, K.11
Yazumi, S.12
Chiba, T.13
Guha, S.14
Aggarwal, B.B.15
-
42
-
-
51649118928
-
Phase II trial of curcumin in patients with advanced pancreatic cancer
-
10.1158/1078-0432.CCR-08-0024, 18628464
-
Dhillon N, Aggarwal BB, Newman RA, Wolff RA, Kunnumakkara AB, Abbruzzese JL, Ng CS, Badmaev V, Kurzrock R. Phase II trial of curcumin in patients with advanced pancreatic cancer. Clin Cancer Res 2008, 14:4491-4499. 10.1158/1078-0432.CCR-08-0024, 18628464.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4491-4499
-
-
Dhillon, N.1
Aggarwal, B.B.2
Newman, R.A.3
Wolff, R.A.4
Kunnumakkara, A.B.5
Abbruzzese, J.L.6
Ng, C.S.7
Badmaev, V.8
Kurzrock, R.9
-
43
-
-
67650214705
-
Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae
-
10.1016/j.jpba.2009.04.028, 19481403
-
Li C, Zhou L, Lin G, Zuo Z. Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae. J Pharm Biomed Anal 2009, 50:298-306. 10.1016/j.jpba.2009.04.028, 19481403.
-
(2009)
J Pharm Biomed Anal
, vol.50
, pp. 298-306
-
-
Li, C.1
Zhou, L.2
Lin, G.3
Zuo, Z.4
-
44
-
-
41349116311
-
Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCγ1- and Ca2+ -dependent apoptosis
-
10.1182/blood-2007-06-096198, 18070986
-
Baumann S, Fas SC, Giaisi M, Müller WW, Merling A, Gülow K, Edler L, Krammer PH, Li-Weber M. Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCγ1- and Ca2+ -dependent apoptosis. Blood 2008, 111:2354-2363. 10.1182/blood-2007-06-096198, 18070986.
-
(2008)
Blood
, vol.111
, pp. 2354-2363
-
-
Baumann, S.1
Fas, S.C.2
Giaisi, M.3
Müller, W.W.4
Merling, A.5
Gülow, K.6
Edler, L.7
Krammer, P.H.8
Li-Weber, M.9
-
45
-
-
33947171644
-
Changes in mitochondrial membrane potential and reactive oxygen species during wogonin-induced cell death in human hepatoma cells
-
10.1111/j.1872-034X.2007.00003.x, 17300700
-
Yu JQ, Liu HB, Tian DZ, Liu YW, Lei JC, Zou GL. Changes in mitochondrial membrane potential and reactive oxygen species during wogonin-induced cell death in human hepatoma cells. Hepatol Res 2007, 37:68-76. 10.1111/j.1872-034X.2007.00003.x, 17300700.
-
(2007)
Hepatol Res
, vol.37
, pp. 68-76
-
-
Yu, J.Q.1
Liu, H.B.2
Tian, D.Z.3
Liu, Y.W.4
Lei, J.C.5
Zou, G.L.6
-
46
-
-
33845642523
-
Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell
-
10.1016/j.canlet.2006.01.011, 16497434
-
Himeji M, Ohtsuki T, Fukazawa H, Tanaka M, Yazaki S, Ui S, Nishio K, Yamamoto H, Tasaka K, Mimura A. Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell. Cancer Lett 2007, 245:269-274. 10.1016/j.canlet.2006.01.011, 16497434.
-
(2007)
Cancer Lett
, vol.245
, pp. 269-274
-
-
Himeji, M.1
Ohtsuki, T.2
Fukazawa, H.3
Tanaka, M.4
Yazaki, S.5
Ui, S.6
Nishio, K.7
Yamamoto, H.8
Tasaka, K.9
Mimura, A.10
-
47
-
-
43049090780
-
Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells
-
10.1016/j.bcp.2008.02.023, 2424318, 18377871
-
Lee D-H, Kim C, Zhang L, Lee YJ. Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. Biochem Pharmacol 2008, 75:2020-2033. 10.1016/j.bcp.2008.02.023, 2424318, 18377871.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 2020-2033
-
-
Lee, D.-H.1
Kim, C.2
Zhang, L.3
Lee, Y.J.4
-
48
-
-
74549113847
-
Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells
-
10.1139/O09-060, 19935879
-
Yang L, Zhang HW, Hu R, Yang Y, Qi Q, Lu N, Liu W, Chu YY, You QD, Guo QL. Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells. Biochem Cell Biol 2009, 87:933-942. 10.1139/O09-060, 19935879.
-
(2009)
Biochem Cell Biol
, vol.87
, pp. 933-942
-
-
Yang, L.1
Zhang, H.W.2
Hu, R.3
Yang, Y.4
Qi, Q.5
Lu, N.6
Liu, W.7
Chu, Y.Y.8
You, Q.D.9
Guo, Q.L.10
-
49
-
-
41749102871
-
Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2
-
10.1016/j.lfs.2008.02.013, 18378261
-
Lu N, Gao Y, Ling Y, Chen Y, Yang Y, Gu H-Y, Qi Q, Liu W, Wang X-T, You Q-D, Guo Q-L. Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. Life Sci 2008, 82:956-963. 10.1016/j.lfs.2008.02.013, 18378261.
-
(2008)
Life Sci
, vol.82
, pp. 956-963
-
-
Lu, N.1
Gao, Y.2
Ling, Y.3
Chen, Y.4
Yang, Y.5
Gu, H.-Y.6
Qi, Q.7
Liu, W.8
Wang, X.-T.9
You, Q.-D.10
Guo, Q.-L.11
-
50
-
-
69149091652
-
Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells
-
10.1111/j.1749-6632.2009.04722.x, 19723047
-
Lee E, Enomoto R, Koshiba C, Hirano H. Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells. Ann N Y Acad Sci 2009, 1171:132-136. 10.1111/j.1749-6632.2009.04722.x, 19723047.
-
(2009)
Ann N Y Acad Sci
, vol.1171
, pp. 132-136
-
-
Lee, E.1
Enomoto, R.2
Koshiba, C.3
Hirano, H.4
-
51
-
-
34247862144
-
Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells
-
10.1196/annals.1397.056, 17404065
-
Lee E, Enomoto R, Suzuki C, Ohno M, Ohashi T, Miyauchi A, Tanimoto E, Maeda K, Hirano H, Yokoi T, Sugahara C. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. Ann N Y Acad Sci 2007, 1095:521-526. 10.1196/annals.1397.056, 17404065.
-
(2007)
Ann N Y Acad Sci
, vol.1095
, pp. 521-526
-
-
Lee, E.1
Enomoto, R.2
Suzuki, C.3
Ohno, M.4
Ohashi, T.5
Miyauchi, A.6
Tanimoto, E.7
Maeda, K.8
Hirano, H.9
Yokoi, T.10
Sugahara, C.11
-
52
-
-
79955554423
-
Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects
-
10.1007/s00280-010-1396-8, 20658136
-
Enomoto R, Koshiba C, Suzuki C, Lee E. Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. Cancer Chemother Pharmacol 2011, 67:1063-1072. 10.1007/s00280-010-1396-8, 20658136.
-
(2011)
Cancer Chemother Pharmacol
, vol.67
, pp. 1063-1072
-
-
Enomoto, R.1
Koshiba, C.2
Suzuki, C.3
Lee, E.4
-
53
-
-
77954959058
-
Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism
-
10.1016/j.toxlet.2010.05.019, 20570612
-
Zhao Q, Wang J, Zou MJ, Hu R, Zhao L, Qiang L, Rong JJ, You QD, Guo QL. Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism. Toxicol Lett 2010, 197:201-210. 10.1016/j.toxlet.2010.05.019, 20570612.
-
(2010)
Toxicol Lett
, vol.197
, pp. 201-210
-
-
Zhao, Q.1
Wang, J.2
Zou, M.J.3
Hu, R.4
Zhao, L.5
Qiang, L.6
Rong, J.J.7
You, Q.D.8
Guo, Q.L.9
-
54
-
-
58749114381
-
New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin
-
10.1016/j.ctrv.2008.09.005, 19004559
-
Li-Weber M. New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. Cancer Treatment Reviews 2009, 35:57-68. 10.1016/j.ctrv.2008.09.005, 19004559.
-
(2009)
Cancer Treatment Reviews
, vol.35
, pp. 57-68
-
-
Li-Weber, M.1
-
55
-
-
77950255061
-
Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin
-
10.1158/0008-5472.CAN-09-3249, 2840193, 20215518
-
Rajamanickam S, Velmurugan B, Kaur M, Singh RP, Agarwal R. Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin. Cancer Res 2010, 70:2368-2378. 10.1158/0008-5472.CAN-09-3249, 2840193, 20215518.
-
(2010)
Cancer Res
, vol.70
, pp. 2368-2378
-
-
Rajamanickam, S.1
Velmurugan, B.2
Kaur, M.3
Singh, R.P.4
Agarwal, R.5
-
56
-
-
59449097284
-
Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling
-
10.1158/1078-0432.CCR-08-1846, 2629529, 19147767
-
Singh RP, Raina K, Deep G, Chan D, Agarwal R. Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling. Clin Cancer Res 2009, 15:613-621. 10.1158/1078-0432.CCR-08-1846, 2629529, 19147767.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 613-621
-
-
Singh, R.P.1
Raina, K.2
Deep, G.3
Chan, D.4
Agarwal, R.5
-
57
-
-
59449085306
-
Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice
-
10.1158/1078-0432.CCR-08-1309, 2639624, 19047104
-
Singh RP, Raina K, Sharma G, Agarwal R. Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice. Clin Cancer Res 2008, 14:7773-7780. 10.1158/1078-0432.CCR-08-1309, 2639624, 19047104.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7773-7780
-
-
Singh, R.P.1
Raina, K.2
Sharma, G.3
Agarwal, R.4
-
58
-
-
78650447035
-
Silibinin-induced apoptosis in MCF7 and T47D human breast carcinoma cells involves caspase-8 activation and mitochondrial pathway
-
10.3109/07357907.2010.535053, 21166494
-
Tiwari P, Kumar A, Balakrishnan S, Kushwaha HS, Mishra KP. Silibinin-induced apoptosis in MCF7 and T47D human breast carcinoma cells involves caspase-8 activation and mitochondrial pathway. Cancer Invest 2011, 29:12-20. 10.3109/07357907.2010.535053, 21166494.
-
(2011)
Cancer Invest
, vol.29
, pp. 12-20
-
-
Tiwari, P.1
Kumar, A.2
Balakrishnan, S.3
Kushwaha, H.S.4
Mishra, K.P.5
-
59
-
-
67651171486
-
Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice
-
10.3748/wjg.15.1943, 2675083, 19399925
-
Cui W, Gu F, Hu KQ. Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice. World J Gastroenterol 2009, 15:1943-1950. 10.3748/wjg.15.1943, 2675083, 19399925.
-
(2009)
World J Gastroenterol
, vol.15
, pp. 1943-1950
-
-
Cui, W.1
Gu, F.2
Hu, K.Q.3
-
60
-
-
53049106036
-
Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model
-
10.1158/0008-5472.CAN-08-1332, 2587411, 18701508
-
Raina K, Rajamanickam S, Singh RP, Deep G, Chittezhath M, Agarwal R. Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model. Cancer Res 2008, 68:6822-6830. 10.1158/0008-5472.CAN-08-1332, 2587411, 18701508.
-
(2008)
Cancer Res
, vol.68
, pp. 6822-6830
-
-
Raina, K.1
Rajamanickam, S.2
Singh, R.P.3
Deep, G.4
Chittezhath, M.5
Agarwal, R.6
-
61
-
-
77949907818
-
Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators
-
3049548, 19908243
-
Mateen S, Tyagi A, Agarwal C, Singh RP, Agarwal R. Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators. Mol Carcinog 2010, 49:247-258. 3049548, 19908243.
-
(2010)
Mol Carcinog
, vol.49
, pp. 247-258
-
-
Mateen, S.1
Tyagi, A.2
Agarwal, C.3
Singh, R.P.4
Agarwal, R.5
-
62
-
-
74549146799
-
Targeting silibinin in the antiproliferative pathway
-
10.1517/13543780903533631, 20047507
-
Li L, Zeng J, Gao Y, He D. Targeting silibinin in the antiproliferative pathway. Expert Opin Investig Drugs 2010, 19:243-255. 10.1517/13543780903533631, 20047507.
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 243-255
-
-
Li, L.1
Zeng, J.2
Gao, Y.3
He, D.4
-
63
-
-
34547829030
-
Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells
-
10.1093/carcin/bgm042, 17341659
-
Agarwal C, Tyagi A, Kaur M, Agarwal R. Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells. Carcinogenesis 2007, 28:1463-1470. 10.1093/carcin/bgm042, 17341659.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1463-1470
-
-
Agarwal, C.1
Tyagi, A.2
Kaur, M.3
Agarwal, R.4
-
64
-
-
78649843971
-
Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3)
-
Wang X, Gocek E, Novik V, Harrison JS, Danilenko M, Studzinski GP. Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3). Cell Cycle 2010, 9:4542-4551.
-
(2010)
Cell Cycle
, vol.9
, pp. 4542-4551
-
-
Wang, X.1
Gocek, E.2
Novik, V.3
Harrison, J.S.4
Danilenko, M.5
Studzinski, G.P.6
-
65
-
-
0002050785
-
Pressurized liquid extraction of berberine and aristolochic acids in medicinal plants
-
10.1016/S0021-9673(00)00914-6, 11209901
-
Ong ES, Woo SO, Yong YL. Pressurized liquid extraction of berberine and aristolochic acids in medicinal plants. J Chromatogr A 2000, 904:57-64. 10.1016/S0021-9673(00)00914-6, 11209901.
-
(2000)
J Chromatogr A
, vol.904
, pp. 57-64
-
-
Ong, E.S.1
Woo, S.O.2
Yong, Y.L.3
-
66
-
-
77957726821
-
Berberine ameliorates TNBS-induced colitis by inhibiting lipid peroxidation, enterobacterial growth and NF-kappaB activation
-
10.1016/j.ejphar.2010.08.046, 20828550
-
Lee IA, Hyun YJ, Kim DH. Berberine ameliorates TNBS-induced colitis by inhibiting lipid peroxidation, enterobacterial growth and NF-kappaB activation. Eur J Pharmacol 2010, 648:162-170. 10.1016/j.ejphar.2010.08.046, 20828550.
-
(2010)
Eur J Pharmacol
, vol.648
, pp. 162-170
-
-
Lee, I.A.1
Hyun, Y.J.2
Kim, D.H.3
-
67
-
-
78649385842
-
Beneficial effect of berberine on hepatic insulin resistance in diabetic hamsters possibly involves in SREBPs, LXRalpha and PPARalpha transcriptional programs
-
10.1507/endocrj.K10E-043, 20724798
-
Liu X, Li G, Zhu H, Huang L, Liu Y, Ma C, Qin C. Beneficial effect of berberine on hepatic insulin resistance in diabetic hamsters possibly involves in SREBPs, LXRalpha and PPARalpha transcriptional programs. Endocr J 2010, 57:881-893. 10.1507/endocrj.K10E-043, 20724798.
-
(2010)
Endocr J
, vol.57
, pp. 881-893
-
-
Liu, X.1
Li, G.2
Zhu, H.3
Huang, L.4
Liu, Y.5
Ma, C.6
Qin, C.7
-
68
-
-
78049235146
-
Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes
-
10.1016/j.ejphar.2010.09.030, 20868663
-
Zhou J, Zhou S. Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes. Eur J Pharmacol 2010, 649:390-397. 10.1016/j.ejphar.2010.09.030, 20868663.
-
(2010)
Eur J Pharmacol
, vol.649
, pp. 390-397
-
-
Zhou, J.1
Zhou, S.2
-
69
-
-
77954474171
-
Advance of studies on anti-atherosclerosis mechanism of berberine
-
10.1007/s11655-010-0188-7, 20473748
-
Wu M, Wang J, Liu LT. Advance of studies on anti-atherosclerosis mechanism of berberine. Chin J Integr Med 2010, 16:188-192. 10.1007/s11655-010-0188-7, 20473748.
-
(2010)
Chin J Integr Med
, vol.16
, pp. 188-192
-
-
Wu, M.1
Wang, J.2
Liu, L.T.3
-
70
-
-
78650414876
-
Berberine reduces insulin resistance induced by dexamethasone in theca cells in vitro
-
10.1016/j.fertnstert.2010.07.1090, 20840879
-
Zhao L, Li W, Han F, Hou L, Baillargeon JP, Kuang H, Wang Y, Wu X. Berberine reduces insulin resistance induced by dexamethasone in theca cells in vitro. Fertil Steril 2011, 95:461-463. 10.1016/j.fertnstert.2010.07.1090, 20840879.
-
(2011)
Fertil Steril
, vol.95
, pp. 461-463
-
-
Zhao, L.1
Li, W.2
Han, F.3
Hou, L.4
Baillargeon, J.P.5
Kuang, H.6
Wang, Y.7
Wu, X.8
-
71
-
-
77955406469
-
Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway
-
2905940, 20652055
-
Remppis A, Bea F, Greten HJ, Buttler A, Wang H, Zhou Q, Preusch MR, Enk R, Ehehalt R, Katus H, Blessing E. Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway. Mediators Inflamm 2010, 2010:194896. 2905940, 20652055.
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 194896
-
-
Remppis, A.1
Bea, F.2
Greten, H.J.3
Buttler, A.4
Wang, H.5
Zhou, Q.6
Preusch, M.R.7
Enk, R.8
Ehehalt, R.9
Katus, H.10
Blessing, E.11
-
72
-
-
58149163569
-
Berberine inhibits human neuroblastoma cell growth through induction of p53-dependent apoptosis
-
Choi MS, Yuk DY, Oh JH, Jung HY, Han SB, Moon DC, Hong JT. Berberine inhibits human neuroblastoma cell growth through induction of p53-dependent apoptosis. Anticancer Res 2008, 28:3777-3784.
-
(2008)
Anticancer Res
, vol.28
, pp. 3777-3784
-
-
Choi, M.S.1
Yuk, D.Y.2
Oh, J.H.3
Jung, H.Y.4
Han, S.B.5
Moon, D.C.6
Hong, J.T.7
-
73
-
-
71949097349
-
Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells
-
Ho YT, Lu CC, Yang JS, Chiang JH, Li TC, Ip SW, Hsia TC, Liao CL, Lin JG, Wood WG, Chung JG. Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells. Anticancer Res 2009, 29:4063-4070.
-
(2009)
Anticancer Res
, vol.29
, pp. 4063-4070
-
-
Ho, Y.T.1
Lu, C.C.2
Yang, J.S.3
Chiang, J.H.4
Li, T.C.5
Ip, S.W.6
Hsia, T.C.7
Liao, C.L.8
Lin, J.G.9
Wood, W.G.10
Chung, J.G.11
-
74
-
-
34848844388
-
Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL
-
10.1007/s00204-006-0169-y, 17673978
-
Hsu WH, Hsieh YS, Kuo HC, Teng CY, Huang HI, Wang CJ, Yang SF, Liou YS, Kuo WH. Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL. Arch Toxicol 2007, 81:719-728. 10.1007/s00204-006-0169-y, 17673978.
-
(2007)
Arch Toxicol
, vol.81
, pp. 719-728
-
-
Hsu, W.H.1
Hsieh, Y.S.2
Kuo, H.C.3
Teng, C.Y.4
Huang, H.I.5
Wang, C.J.6
Yang, S.F.7
Liou, Y.S.8
Kuo, W.H.9
-
75
-
-
78650185177
-
Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis
-
10.1002/mc.20690, 21061266
-
James MA, Fu H, Liu Y, Chen DR, You M. Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis. Mol Carcinog 2011, 50:1-7. 10.1002/mc.20690, 21061266.
-
(2011)
Mol Carcinog
, vol.50
, pp. 1-7
-
-
James, M.A.1
Fu, H.2
Liu, Y.3
Chen, D.R.4
You, M.5
-
76
-
-
77956190161
-
Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway
-
10.1016/j.ejphar.2010.07.037, 20691179
-
Patil JB, Kim J, Jayaprakasha GK. Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway. Eur J Pharmacol 2010, 645:70-78. 10.1016/j.ejphar.2010.07.037, 20691179.
-
(2010)
Eur J Pharmacol
, vol.645
, pp. 70-78
-
-
Patil, J.B.1
Kim, J.2
Jayaprakasha, G.K.3
-
77
-
-
70350752049
-
Coptis chinensis inhibits hepatocellular carcinoma cell growth through nonsteroidal anti-inflammatory drug-activated gene activation
-
Auyeung KK, Ko JK. Coptis chinensis inhibits hepatocellular carcinoma cell growth through nonsteroidal anti-inflammatory drug-activated gene activation. Int J Mol Med 2009, 24:571-577.
-
(2009)
Int J Mol Med
, vol.24
, pp. 571-577
-
-
Auyeung, K.K.1
Ko, J.K.2
-
78
-
-
34047217905
-
Berberine inhibits WEHI-3 leukemia cells in vivo
-
Yu FS, Yang JS, Lin HJ, Yu CS, Tan TW, Lin YT, Lin CC, Lu HF, Chung JG. Berberine inhibits WEHI-3 leukemia cells in vivo. In Vivo 2007, 21:407-412.
-
(2007)
In Vivo
, vol.21
, pp. 407-412
-
-
Yu, F.S.1
Yang, J.S.2
Lin, H.J.3
Yu, C.S.4
Tan, T.W.5
Lin, Y.T.6
Lin, C.C.7
Lu, H.F.8
Chung, J.G.9
-
79
-
-
42749085774
-
Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation
-
10.1016/j.taap.2007.12.027, 18275980
-
Meeran SM, Katiyar S, Katiyar SK. Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation. Toxicol Appl Pharmacol 2008, 229:33-43. 10.1016/j.taap.2007.12.027, 18275980.
-
(2008)
Toxicol Appl Pharmacol
, vol.229
, pp. 33-43
-
-
Meeran, S.M.1
Katiyar, S.2
Katiyar, S.K.3
-
80
-
-
48549105216
-
Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis
-
10.1158/0008-5472.CAN-08-0511, 18593939
-
Pandey MK, Sung B, Kunnumakkara AB, Sethi G, Chaturvedi MM, Aggarwal BB. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis. Cancer Res 2008, 68:5370-5379. 10.1158/0008-5472.CAN-08-0511, 18593939.
-
(2008)
Cancer Res
, vol.68
, pp. 5370-5379
-
-
Pandey, M.K.1
Sung, B.2
Kunnumakkara, A.B.3
Sethi, G.4
Chaturvedi, M.M.5
Aggarwal, B.B.6
-
81
-
-
34248594357
-
Inhibition of DNA topoisomerase I by natural and synthetic mono- and dimeric protoberberine alkaloids
-
10.1002/cbdv.200790040, 17372950
-
Qin Y, Pang JY, Chen WH, Zhao ZZ, Liu L, Jiang ZH. Inhibition of DNA topoisomerase I by natural and synthetic mono- and dimeric protoberberine alkaloids. Chem Biodivers 2007, 4:481-487. 10.1002/cbdv.200790040, 17372950.
-
(2007)
Chem Biodivers
, vol.4
, pp. 481-487
-
-
Qin, Y.1
Pang, J.Y.2
Chen, W.H.3
Zhao, Z.Z.4
Liu, L.5
Jiang, Z.H.6
-
82
-
-
58849122415
-
P53 Cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo
-
10.1002/mc.20453, 18459128
-
Katiyar SK, Meeran SM, Katiyar N, Akhtar S. p53 Cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo. Mol Carcinog 2009, 48:24-37. 10.1002/mc.20453, 18459128.
-
(2009)
Mol Carcinog
, vol.48
, pp. 24-37
-
-
Katiyar, S.K.1
Meeran, S.M.2
Katiyar, N.3
Akhtar, S.4
-
83
-
-
81455123778
-
Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer
-
2915887, 20814427
-
Maiti M, Kumar GS. Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer. J Nucleic Acids 2010, 2010. 2915887, 20814427.
-
(2010)
J Nucleic Acids
, vol.2010
-
-
Maiti, M.1
Kumar, G.S.2
-
84
-
-
77951976781
-
Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: Binding aspects and implications for drug design
-
Bhadra K, Kumar GS. Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: Binding aspects and implications for drug design. Med Res Rev 2010,
-
(2010)
Med Res Rev
-
-
Bhadra, K.1
Kumar, G.S.2
-
85
-
-
44649160611
-
Interaction of anticancer herbal drug berberine with DNA immobilized on the glassy carbon electrode
-
10.1016/j.bioelechem.2008.02.005, 18455966
-
Tian X, Song Y, Dong H, Ye B. Interaction of anticancer herbal drug berberine with DNA immobilized on the glassy carbon electrode. Bioelectrochemistry 2008, 73:18-22. 10.1016/j.bioelechem.2008.02.005, 18455966.
-
(2008)
Bioelectrochemistry
, vol.73
, pp. 18-22
-
-
Tian, X.1
Song, Y.2
Dong, H.3
Ye, B.4
-
86
-
-
41049098849
-
Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line
-
10.1007/s00280-007-0558-9, 17661039
-
Serafim TL, Oliveira PJ, Sardao VA, Perkins E, Parke D, Holy J. Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line. Cancer Chemother Pharmacol 2008, 61:1007-1018. 10.1007/s00280-007-0558-9, 17661039.
-
(2008)
Cancer Chemother Pharmacol
, vol.61
, pp. 1007-1018
-
-
Serafim, T.L.1
Oliveira, P.J.2
Sardao, V.A.3
Perkins, E.4
Parke, D.5
Holy, J.6
-
87
-
-
77950020488
-
The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest
-
10.1016/j.phymed.2009.08.012, 19800775
-
Kim JB, Yu JH, Ko E, Lee KW, Song AK, Park SY, Shin I, Han W, Noh DY. The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest. Phytomedicine 2010, 17:436-440. 10.1016/j.phymed.2009.08.012, 19800775.
-
(2010)
Phytomedicine
, vol.17
, pp. 436-440
-
-
Kim, J.B.1
Yu, J.H.2
Ko, E.3
Lee, K.W.4
Song, A.K.5
Park, S.Y.6
Shin, I.7
Han, W.8
Noh, D.Y.9
-
88
-
-
41849122326
-
Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through mitochondrial/caspases pathway
-
10.1248/bpb.31.558, 18379040
-
Eom KS, Hong JM, Youn MJ, So HS, Park R, Kim JM, Kim TY. Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through mitochondrial/caspases pathway. Biol Pharm Bull 2008, 31:558-562. 10.1248/bpb.31.558, 18379040.
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 558-562
-
-
Eom, K.S.1
Hong, J.M.2
Youn, M.J.3
So, H.S.4
Park, R.5
Kim, J.M.6
Kim, T.Y.7
-
89
-
-
51849122083
-
Mechanisms of berberine (natural yellow 18)-induced mitochondrial dysfunction: interaction with the adenine nucleotide translocator
-
10.1093/toxsci/kfn131, 18599498
-
Pereira CV, Machado NG, Oliveira PJ. Mechanisms of berberine (natural yellow 18)-induced mitochondrial dysfunction: interaction with the adenine nucleotide translocator. Toxicol Sci 2008, 105:408-417. 10.1093/toxsci/kfn131, 18599498.
-
(2008)
Toxicol Sci
, vol.105
, pp. 408-417
-
-
Pereira, C.V.1
Machado, N.G.2
Oliveira, P.J.3
-
90
-
-
78649775152
-
Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism
-
10.1002/jcb.22869, 20830746
-
Wang N, Feng Y, Zhu M, Tsang CM, Man K, Tong Y, Tsao SW. Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism. J Cell Biochem 2010, 111:1426-1436. 10.1002/jcb.22869, 20830746.
-
(2010)
J Cell Biochem
, vol.111
, pp. 1426-1436
-
-
Wang, N.1
Feng, Y.2
Zhu, M.3
Tsang, C.M.4
Man, K.5
Tong, Y.6
Tsao, S.W.7
-
91
-
-
38149008948
-
Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell death
-
10.1016/j.ijrobp.2007.08.034, 18207031
-
Peng PL, Kuo WH, Tseng HC, Chou FP. Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell death. Int J Radiat Oncol Biol Phys 2008, 70:529-542. 10.1016/j.ijrobp.2007.08.034, 18207031.
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.70
, pp. 529-542
-
-
Peng, P.L.1
Kuo, W.H.2
Tseng, H.C.3
Chou, F.P.4
-
92
-
-
79952198976
-
Berberine, an isoquinoline alkaloid, inhibits melanoma cancer cell migration by reducing the expressions of cyclooxygenase-2, prostaglandin E and prostaglandin E receptors
-
10.1093/carcin/bgq215, 20974686
-
Singh T, Vaid M, Katiyar N, Sharma S, Katiyar SK. Berberine, an isoquinoline alkaloid, inhibits melanoma cancer cell migration by reducing the expressions of cyclooxygenase-2, prostaglandin E and prostaglandin E receptors. Carcinogenesis 2011, 32:86-92. 10.1093/carcin/bgq215, 20974686.
-
(2011)
Carcinogenesis
, vol.32
, pp. 86-92
-
-
Singh, T.1
Vaid, M.2
Katiyar, N.3
Sharma, S.4
Katiyar, S.K.5
-
93
-
-
67649515350
-
Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells
-
Tsang CM, Lau EP, Di K, Cheung PY, Hau PM, Ching YP, Wong YC, Cheung AL, Wan TS, Tong Y, Tsao SW, Feng Y. Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells. Int J Mol Med 2009, 24:131-138.
-
(2009)
Int J Mol Med
, vol.24
, pp. 131-138
-
-
Tsang, C.M.1
Lau, E.P.2
Di, K.3
Cheung, P.Y.4
Hau, P.M.5
Ching, Y.P.6
Wong, Y.C.7
Cheung, A.L.8
Wan, T.S.9
Tong, Y.10
Tsao, S.W.11
Feng, Y.12
-
94
-
-
70350459062
-
Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567
-
10.1074/jbc.M109.033795, 2785675, 19651779
-
Tang F, Wang D, Duan C, Huang D, Wu Y, Chen Y, Wang W, Xie C, Meng J, Wang L, Wu B, Liu S, Tian D, Zhu F, He Z, Deng F, Cao Y. Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567. J Biol Chem 2009, 284:27456-27466. 10.1074/jbc.M109.033795, 2785675, 19651779.
-
(2009)
J Biol Chem
, vol.284
, pp. 27456-27466
-
-
Tang, F.1
Wang, D.2
Duan, C.3
Huang, D.4
Wu, Y.5
Chen, Y.6
Wang, W.7
Xie, C.8
Meng, J.9
Wang, L.10
Wu, B.11
Liu, S.12
Tian, D.13
Zhu, F.14
He, Z.15
Deng, F.16
Cao, Y.17
-
95
-
-
41549102101
-
Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide
-
10.1186/1471-2407-8-58, 2275285, 18294404
-
Lin TH, Kuo HC, Chou FP, Lu FJ. Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide. BMC Cancer 2008, 8:58. 10.1186/1471-2407-8-58, 2275285, 18294404.
-
(2008)
BMC Cancer
, vol.8
, pp. 58
-
-
Lin, T.H.1
Kuo, H.C.2
Chou, F.P.3
Lu, F.J.4
-
96
-
-
70349930398
-
Enhancement of Arsenic Trioxide (As(2)O(3))- Mediated Apoptosis Using Berberine in Human Neuroblastoma SH-SY5Y Cells
-
10.3340/jkns.2007.42.5.392, 2588187, 19096576
-
Kim DW, Ahan SH, Kim TY. Enhancement of Arsenic Trioxide (As(2)O(3))- Mediated Apoptosis Using Berberine in Human Neuroblastoma SH-SY5Y Cells. J Korean Neurosurg Soc 2007, 42:392-399. 10.3340/jkns.2007.42.5.392, 2588187, 19096576.
-
(2007)
J Korean Neurosurg Soc
, vol.42
, pp. 392-399
-
-
Kim, D.W.1
Ahan, S.H.2
Kim, T.Y.3
-
97
-
-
44349121204
-
Berberine, a natural product, combined with cisplatin enhanced apoptosis through a mitochondria/caspase-mediated pathway in HeLa cells
-
10.1248/bpb.31.789, 18451495
-
Youn MJ, So HS, Cho HJ, Kim HJ, Kim Y, Lee JH, Sohn JS, Kim YK, Chung SY, Park R. Berberine, a natural product, combined with cisplatin enhanced apoptosis through a mitochondria/caspase-mediated pathway in HeLa cells. Biol Pharm Bull 2008, 31:789-795. 10.1248/bpb.31.789, 18451495.
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 789-795
-
-
Youn, M.J.1
So, H.S.2
Cho, H.J.3
Kim, H.J.4
Kim, Y.5
Lee, J.H.6
Sohn, J.S.7
Kim, Y.K.8
Chung, S.Y.9
Park, R.10
-
98
-
-
67749133572
-
The combination of berberine and irradiation enhances anti-cancer effects via activation of p38 MAPK pathway and ROS generation in human hepatoma cells
-
10.1002/jcb.22198, 19492307
-
Hur JM, Hyun MS, Lim SY, Lee WY, Kim D. The combination of berberine and irradiation enhances anti-cancer effects via activation of p38 MAPK pathway and ROS generation in human hepatoma cells. J Cell Biochem 2009, 107:955-964. 10.1002/jcb.22198, 19492307.
-
(2009)
J Cell Biochem
, vol.107
, pp. 955-964
-
-
Hur, J.M.1
Hyun, M.S.2
Lim, S.Y.3
Lee, W.Y.4
Kim, D.5
-
99
-
-
78649938412
-
Degradation of MDM2 by the interaction between berberine and DAXX leads to potent apoptosis in MDM2-overexpressing cancer cells
-
10.1158/0008-5472.CAN-10-1546, 20935220
-
Zhang X, Gu L, Li J, Shah N, He J, Yang L, Hu Q, Zhou M. Degradation of MDM2 by the interaction between berberine and DAXX leads to potent apoptosis in MDM2-overexpressing cancer cells. Cancer Res 2010, 70:9895-9904. 10.1158/0008-5472.CAN-10-1546, 20935220.
-
(2010)
Cancer Res
, vol.70
, pp. 9895-9904
-
-
Zhang, X.1
Gu, L.2
Li, J.3
Shah, N.4
He, J.5
Yang, L.6
Hu, Q.7
Zhou, M.8
-
100
-
-
48249121084
-
Preparation and evaluation of a microemulsion for oral delivery of berberine
-
Gui SY, Wu L, Peng DY, Liu QY, Yin BP, Shen JZ. Preparation and evaluation of a microemulsion for oral delivery of berberine. Pharmazie 2008, 63:516-519.
-
(2008)
Pharmazie
, vol.63
, pp. 516-519
-
-
Gui, S.Y.1
Wu, L.2
Peng, D.Y.3
Liu, Q.Y.4
Yin, B.P.5
Shen, J.Z.6
-
101
-
-
77955465923
-
8,8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models
-
10.1016/j.bmc.2010.06.085, 20663675
-
Cheng Z, Chen AF, Wu F, Sheng L, Zhang HK, Gu M, Li YY, Zhang LN, Hu LH, Li JY, Li J. 8,8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models. Bioorg Med Chem 2010, 18:5915-5924. 10.1016/j.bmc.2010.06.085, 20663675.
-
(2010)
Bioorg Med Chem
, vol.18
, pp. 5915-5924
-
-
Cheng, Z.1
Chen, A.F.2
Wu, F.3
Sheng, L.4
Zhang, H.K.5
Gu, M.6
Li, Y.Y.7
Zhang, L.N.8
Hu, L.H.9
Li, J.Y.10
Li, J.11
-
102
-
-
0036797498
-
The involvement of P-glycoprotein in berberine absorption
-
10.1034/j.1600-0773.2002.t01-1-910403.x, 12530470
-
Pan GY, Wang GJ, Liu XD, Fawcett JP, Xie YY. The involvement of P-glycoprotein in berberine absorption. Pharmacol Toxicol 2002, 91:193-197. 10.1034/j.1600-0773.2002.t01-1-910403.x, 12530470.
-
(2002)
Pharmacol Toxicol
, vol.91
, pp. 193-197
-
-
Pan, G.Y.1
Wang, G.J.2
Liu, X.D.3
Fawcett, J.P.4
Xie, Y.Y.5
-
103
-
-
53049086416
-
Experimental therapy of hepatoma with artemisinin and its derivatives: in vitro and in vivo activity, chemosensitization, and mechanisms of action
-
10.1158/1078-0432.CCR-08-0197, 18765544
-
Hou J, Wang D, Zhang R, Wang H. Experimental therapy of hepatoma with artemisinin and its derivatives: in vitro and in vivo activity, chemosensitization, and mechanisms of action. Clin Cancer Res 2008, 14:5519-5530. 10.1158/1078-0432.CCR-08-0197, 18765544.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5519-5530
-
-
Hou, J.1
Wang, D.2
Zhang, R.3
Wang, H.4
-
104
-
-
56149102126
-
Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species
-
10.4161/cbt.7.7.6035, 18414062
-
Lu JJ, Meng LH, Cai YJ, Chen Q, Tong LJ, Lin LP, Ding J. Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species. Cancer Biol Ther 2008, 7:1017-1023. 10.4161/cbt.7.7.6035, 18414062.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1017-1023
-
-
Lu, J.J.1
Meng, L.H.2
Cai, Y.J.3
Chen, Q.4
Tong, L.J.5
Lin, L.P.6
Ding, J.7
-
105
-
-
0042844638
-
Molecular modes of action of artesunate in tumor cell lines
-
10.1124/mol.64.2.382, 12869643
-
Efferth T, Sauerbrey A, Olbrich A, Gebhart E, Rauch P, Weber HO, Hengstler JG, Halatsch ME, Volm M, Tew KD, Ross DD, Funk JO. Molecular modes of action of artesunate in tumor cell lines. Mol Pharmacol 2003, 64:382-394. 10.1124/mol.64.2.382, 12869643.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 382-394
-
-
Efferth, T.1
Sauerbrey, A.2
Olbrich, A.3
Gebhart, E.4
Rauch, P.5
Weber, H.O.6
Hengstler, J.G.7
Halatsch, M.E.8
Volm, M.9
Tew, K.D.10
Ross, D.D.11
Funk, J.O.12
-
106
-
-
77952266182
-
Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells
-
10.1016/j.bcp.2010.02.016, 20206143
-
Lu JJ, Meng LH, Shankavaram UT, Zhu CH, Tong LJ, Chen G, Lin LP, Weinstein JN, Ding J. Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells. Biochem Pharmacol 2010, 80:22-30. 10.1016/j.bcp.2010.02.016, 20206143.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 22-30
-
-
Lu, J.J.1
Meng, L.H.2
Shankavaram, U.T.3
Zhu, C.H.4
Tong, L.J.5
Chen, G.6
Lin, L.P.7
Weinstein, J.N.8
Ding, J.9
-
107
-
-
59449109184
-
Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo
-
10.1097/CAD.0b013e3283212ade, 19209030
-
Chen H, Sun B, Pan S, Jiang H, Sun X. Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo. Anticancer Drugs 2009, 20:131-140. 10.1097/CAD.0b013e3283212ade, 19209030.
-
(2009)
Anticancer Drugs
, vol.20
, pp. 131-140
-
-
Chen, H.1
Sun, B.2
Pan, S.3
Jiang, H.4
Sun, X.5
-
108
-
-
34548088377
-
Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway
-
10.1002/ijc.22804, 17520675
-
Li LN, Zhang HD, Yuan SJ, Tian ZY, Wang L, Sun ZX. Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway. Int J Cancer 2007, 121:1360-1365. 10.1002/ijc.22804, 17520675.
-
(2007)
Int J Cancer
, vol.121
, pp. 1360-1365
-
-
Li, L.N.1
Zhang, H.D.2
Yuan, S.J.3
Tian, Z.Y.4
Wang, L.5
Sun, Z.X.6
-
109
-
-
77649189381
-
Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo
-
10.1007/s00280-009-1095-5, 2824122, 19690861
-
Du JH, Zhang HD, Ma ZJ, Ji KM. Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo. Cancer Chemother Pharmacol 2010, 65:895-902. 10.1007/s00280-009-1095-5, 2824122, 19690861.
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, pp. 895-902
-
-
Du, J.H.1
Zhang, H.D.2
Ma, Z.J.3
Ji, K.M.4
-
110
-
-
78651404852
-
The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials
-
10.1074/jbc.M110.144188, 21059641
-
Mercer AE, Copple IM, Maggs JL, O'Neill PM, Park BK. The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials. J Biol Chem 2011, 286:987-996. 10.1074/jbc.M110.144188, 21059641.
-
(2011)
J Biol Chem
, vol.286
, pp. 987-996
-
-
Mercer, A.E.1
Copple, I.M.2
Maggs, J.L.3
O'Neill, P.M.4
Park, B.K.5
-
111
-
-
77952951285
-
Heme synthesis increases artemisinin -induced radical formation and cytotoxicity that can be suppressed by superoxide scavengers
-
10.1016/j.cbi.2010.03.021, 20361947
-
Zhang S, Chen H, Gerhard GS. Heme synthesis increases artemisinin -induced radical formation and cytotoxicity that can be suppressed by superoxide scavengers. Chem Biol Interact 2010, 186:30-35. 10.1016/j.cbi.2010.03.021, 20361947.
-
(2010)
Chem Biol Interact
, vol.186
, pp. 30-35
-
-
Zhang, S.1
Chen, H.2
Gerhard, G.S.3
-
112
-
-
70449562761
-
Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target
-
10.1371/journal.pone.0007472, 2764339, 19862332
-
Zhang S, Gerhard GS. Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target. PLoS ONE 2009, 4:e7472. 10.1371/journal.pone.0007472, 2764339, 19862332.
-
(2009)
PLoS ONE
, vol.4
-
-
Zhang, S.1
Gerhard, G.S.2
-
113
-
-
4444383530
-
Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron
-
10.1016/j.freeradbiomed.2004.06.023, 15336316
-
Efferth T, Benakis A, Romero MR, Tomicic M, Rauh R, Steinbach D, Hafer R, Stamminger T, Oesch F, Kaina B, Marschall M. Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron. Free Radic Biol Med 2004, 37:998-1009. 10.1016/j.freeradbiomed.2004.06.023, 15336316.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 998-1009
-
-
Efferth, T.1
Benakis, A.2
Romero, M.R.3
Tomicic, M.4
Rauh, R.5
Steinbach, D.6
Hafer, R.7
Stamminger, T.8
Oesch, F.9
Kaina, B.10
Marschall, M.11
-
114
-
-
40749110676
-
Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate
-
10.1371/journal.pone.0000798, 1949049, 17726528
-
Kelter G, Steinbach D, Konkimalla VB, Tahara T, Taketani S, Fiebig HH, Efferth T. Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate. PLoS ONE 2007, 2:e798. 10.1371/journal.pone.0000798, 1949049, 17726528.
-
(2007)
PLoS ONE
, vol.2
-
-
Kelter, G.1
Steinbach, D.2
Konkimalla, V.B.3
Tahara, T.4
Taketani, S.5
Fiebig, H.H.6
Efferth, T.7
-
115
-
-
84861595378
-
The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells
-
Lu JJ, Chen SM, Zhang XW, Ding J, Meng LH. The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells. Invest New Drugs 2010,
-
(2010)
Invest New Drugs
-
-
Lu, J.J.1
Chen, S.M.2
Zhang, X.W.3
Ding, J.4
Meng, L.H.5
-
116
-
-
68249142819
-
Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction
-
10.1002/ijc.24496, 2752979, 19533749
-
Stockwin LH, Han B, Yu SX, Hollingshead MG, ElSohly MA, Gul W, Slade D, Galal AM, Newton DL, Bumke MA. Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction. Int J Cancer 2009, 125:1266-1275. 10.1002/ijc.24496, 2752979, 19533749.
-
(2009)
Int J Cancer
, vol.125
, pp. 1266-1275
-
-
Stockwin, L.H.1
Han, B.2
Yu, S.X.3
Hollingshead, M.G.4
ElSohly, M.A.5
Gul, W.6
Slade, D.7
Galal, A.M.8
Newton, D.L.9
Bumke, M.A.10
-
117
-
-
34347389476
-
Dihydroartemisinin is an inhibitor of ovarian cancer cell growth
-
10.1111/j.1745-7254.2007.00612.x, 17588342
-
Jiao Y, Ge CM, Meng QH, Cao JP, Tong J, Fan SJ. Dihydroartemisinin is an inhibitor of ovarian cancer cell growth. Acta pharmacol Sin 2007, 28:1045-1056. 10.1111/j.1745-7254.2007.00612.x, 17588342.
-
(2007)
Acta pharmacol Sin
, vol.28
, pp. 1045-1056
-
-
Jiao, Y.1
Ge, C.M.2
Meng, Q.H.3
Cao, J.P.4
Tong, J.5
Fan, S.J.6
-
118
-
-
77956591096
-
Dihydroartemisinin induces apoptosis by a Bak-dependent intrinsic pathway
-
10.1158/1535-7163.MCT-10-0051, 20663933
-
Handrick R, Ontikatze T, Bauer KD, Freier F, Rubel A, Durig J, Belka C, Jendrossek V. Dihydroartemisinin induces apoptosis by a Bak-dependent intrinsic pathway. Mol Cancer Ther 2010, 9:2497-2510. 10.1158/1535-7163.MCT-10-0051, 20663933.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 2497-2510
-
-
Handrick, R.1
Ontikatze, T.2
Bauer, K.D.3
Freier, F.4
Rubel, A.5
Durig, J.6
Belka, C.7
Jendrossek, V.8
-
119
-
-
68149173166
-
Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy
-
10.1111/j.1582-4934.2008.00360.x, 18466355
-
Chen T, Li M, Zhang R, Wang H. Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy. J Cell Mol Med 2009, 13:1358-1370. 10.1111/j.1582-4934.2008.00360.x, 18466355.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 1358-1370
-
-
Chen, T.1
Li, M.2
Zhang, R.3
Wang, H.4
-
120
-
-
77953714651
-
Dihydroartemisinin upregulates death receptor 5 expression and cooperates with TRAIL to induce apoptosis in human prostate cancer cells
-
10.4161/cbt.9.10.11552, 20224297
-
He Q, Shi J, Shen XL, An J, Sun H, Wang L, Hu YJ, Sun Q, Fu LC, Sheikh MS, Huang Y. Dihydroartemisinin upregulates death receptor 5 expression and cooperates with TRAIL to induce apoptosis in human prostate cancer cells. Cancer Biol Ther 2010, 9:819-824. 10.4161/cbt.9.10.11552, 20224297.
-
(2010)
Cancer Biol Ther
, vol.9
, pp. 819-824
-
-
He, Q.1
Shi, J.2
Shen, X.L.3
An, J.4
Sun, H.5
Wang, L.6
Hu, Y.J.7
Sun, Q.8
Fu, L.C.9
Sheikh, M.S.10
Huang, Y.11
-
121
-
-
34447628307
-
Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells
-
10.1016/j.vph.2007.05.002, 17581794
-
Zhou HJ, Wang WQ, Wu GD, Lee J, Li A. Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells. Vascul Pharmacol 2007, 47:131-138. 10.1016/j.vph.2007.05.002, 17581794.
-
(2007)
Vascul Pharmacol
, vol.47
, pp. 131-138
-
-
Zhou, H.J.1
Wang, W.Q.2
Wu, G.D.3
Lee, J.4
Li, A.5
-
122
-
-
2142650659
-
Antimalarial dihydroartemisinin also inhibits angiogenesis
-
10.1007/s00280-003-0751-4, 15132130
-
Chen HH, Zhou HJ, Wang WQ, Wu GD. Antimalarial dihydroartemisinin also inhibits angiogenesis. Cancer Chemother Pharmacol 2004, 53:423-432. 10.1007/s00280-003-0751-4, 15132130.
-
(2004)
Cancer Chemother Pharmacol
, vol.53
, pp. 423-432
-
-
Chen, H.H.1
Zhou, H.J.2
Wang, W.Q.3
Wu, G.D.4
-
123
-
-
33746531759
-
Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins
-
Anfosso L, Efferth T, Albini A, Pfeffer U. Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins. Pharmacogenomics J 2006, 6:269-278.
-
(2006)
Pharmacogenomics J
, vol.6
, pp. 269-278
-
-
Anfosso, L.1
Efferth, T.2
Albini, A.3
Pfeffer, U.4
-
124
-
-
28844487481
-
Dihydroartemisinin downregulates vascular endothelial growth factor expression and induces apoptosis in chronic myeloid leukemia K562 cells
-
10.1007/s00280-005-0002-y, 16075280
-
Lee J, Zhou HJ, Wu XH. Dihydroartemisinin downregulates vascular endothelial growth factor expression and induces apoptosis in chronic myeloid leukemia K562 cells. Cancer Chemother Pharmacol 2006, 57:213-220. 10.1007/s00280-005-0002-y, 16075280.
-
(2006)
Cancer Chemother Pharmacol
, vol.57
, pp. 213-220
-
-
Lee, J.1
Zhou, H.J.2
Wu, X.H.3
-
125
-
-
70349260586
-
Artemisinin reduces human melanoma cell migration by down-regulating alpha V beta 3 integrin and reducing metalloproteinase 2 production
-
10.1007/s10637-008-9188-2, 18956140
-
Buommino E, Baroni A, Canozo N, Petrazzuolo M, Nicoletti R, Vozza A, Tufano MA. Artemisinin reduces human melanoma cell migration by down-regulating alpha V beta 3 integrin and reducing metalloproteinase 2 production. Invest New Drugs 2009, 27:412-418. 10.1007/s10637-008-9188-2, 18956140.
-
(2009)
Invest New Drugs
, vol.27
, pp. 412-418
-
-
Buommino, E.1
Baroni, A.2
Canozo, N.3
Petrazzuolo, M.4
Nicoletti, R.5
Vozza, A.6
Tufano, M.A.7
-
126
-
-
77955641219
-
First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases
-
10.1002/ijc.25315, 20232396
-
Rasheed SA, Efferth T, Asangani IA, Allgayer H. First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases. Int J Cancer 2010, 127:1475-1485. 10.1002/ijc.25315, 20232396.
-
(2010)
Int J Cancer
, vol.127
, pp. 1475-1485
-
-
Rasheed, S.A.1
Efferth, T.2
Asangani, I.A.3
Allgayer, H.4
-
127
-
-
1842685184
-
Combination treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774
-
10.1016/j.bcp.2003.12.035, 15081868
-
Efferth T, Ramirez T, Gebhart E, Halatsch ME. Combination treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774. Biochem Pharmacol 2004, 67:1689-1700. 10.1016/j.bcp.2003.12.035, 15081868.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 1689-1700
-
-
Efferth, T.1
Ramirez, T.2
Gebhart, E.3
Halatsch, M.E.4
-
128
-
-
77954936163
-
Antineoplastic effect of beta-elemene on prostate cancer cells and other types of solid tumour cells
-
Li QQ, Wang GD, Huang FR, Banda M, Reed E. Antineoplastic effect of beta-elemene on prostate cancer cells and other types of solid tumour cells. J Pharm Pharmacol 2010, 62:1018-1027.
-
(2010)
J Pharm Pharmacol
, vol.62
, pp. 1018-1027
-
-
Li, Q.Q.1
Wang, G.D.2
Huang, F.R.3
Banda, M.4
Reed, E.5
-
129
-
-
18544369255
-
Antitumor effect of beta-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death
-
10.1007/s00018-005-5017-3, 15868411
-
Wang G, Li X, Huang F, Zhao J, Ding H, Cunningham C, Coad JE, Flynn DC, Reed E, Li QQ. Antitumor effect of beta-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death. Cell Mol Life Sci 2005, 62:881-893. 10.1007/s00018-005-5017-3, 15868411.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 881-893
-
-
Wang, G.1
Li, X.2
Huang, F.3
Zhao, J.4
Ding, H.5
Cunningham, C.6
Coad, J.E.7
Flynn, D.C.8
Reed, E.9
Li, Q.Q.10
-
130
-
-
18544381215
-
Antiproliferative effect of beta-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase
-
10.1007/s00018-005-5027-1, 15868412
-
Li X, Wang G, Zhao J, Ding H, Cunningham C, Chen F, Flynn DC, Reed E, Li QQ. Antiproliferative effect of beta-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase. Cell Mol Life Sci 2005, 62:894-904. 10.1007/s00018-005-5027-1, 15868412.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 894-904
-
-
Li, X.1
Wang, G.2
Zhao, J.3
Ding, H.4
Cunningham, C.5
Chen, F.6
Flynn, D.C.7
Reed, E.8
Li, Q.Q.9
-
131
-
-
35148900318
-
In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma
-
Zhao J, Li QQ, Zou B, Wang G, Li X, Kim JE, Cuff CF, Huang L, Reed E, Gardner K. In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma. Inter J Oncol 2007, 31:241-252.
-
(2007)
Inter J Oncol
, vol.31
, pp. 241-252
-
-
Zhao, J.1
Li, Q.Q.2
Zou, B.3
Wang, G.4
Li, X.5
Kim, J.E.6
Cuff, C.F.7
Huang, L.8
Reed, E.9
Gardner, K.10
-
132
-
-
42649116109
-
Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation
-
10.1016/j.canlet.2008.01.049, 18442668
-
Yao YQ, Ding X, Jia YC, Huang CX, Wang YZ, Xu YH. Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation. Cancer Lett 2008, 264:127-134. 10.1016/j.canlet.2008.01.049, 18442668.
-
(2008)
Cancer Lett
, vol.264
, pp. 127-134
-
-
Yao, Y.Q.1
Ding, X.2
Jia, Y.C.3
Huang, C.X.4
Wang, Y.Z.5
Xu, Y.H.6
-
133
-
-
33645990875
-
Elemene displays anti-cancer ability on laryngeal cancer cells in vitro and in vivo
-
10.1007/s00280-005-0137-x, 16283311
-
Tao L, Zhou L, Zheng L, Yao M. Elemene displays anti-cancer ability on laryngeal cancer cells in vitro and in vivo. Cancer Chemother Pharmacol 2006, 58:24-34. 10.1007/s00280-005-0137-x, 16283311.
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 24-34
-
-
Tao, L.1
Zhou, L.2
Zheng, L.3
Yao, M.4
-
134
-
-
75749157017
-
An investigation of the ability of elemene to pass through the blood-brain barrier and its effect on brain carcinomas
-
Wu XS, Xie T, Lin J, Fan HZ, Huang-Fu HJ, Ni LF, Yan HF. An investigation of the ability of elemene to pass through the blood-brain barrier and its effect on brain carcinomas. J Pharm Pharmacol 2009, 61:1653-1656.
-
(2009)
J Pharm Pharmacol
, vol.61
, pp. 1653-1656
-
-
Wu, X.S.1
Xie, T.2
Lin, J.3
Fan, H.Z.4
Huang-Fu, H.J.5
Ni, L.F.6
Yan, H.F.7
-
135
-
-
79960965734
-
Qualitative and quantitative evaluation of Rabdosia Rubescens (Hemls.) Hara of different areas
-
Liao WL, Du Z, Zhang T, Guo XL, Wen YT, Yu Q, Luo AQ, Li WM. Qualitative and quantitative evaluation of Rabdosia Rubescens (Hemls.) Hara of different areas. Central South Pharmacy 2010, 12:912-915.
-
(2010)
Central South Pharmacy
, vol.12
, pp. 912-915
-
-
Liao, W.L.1
Du, Z.2
Zhang, T.3
Guo, X.L.4
Wen, Y.T.5
Yu, Q.6
Luo, A.Q.7
Li, W.M.8
-
136
-
-
32144432114
-
Antiproliferation effects of oridonin on HPB-ALL cells and its mechanisms of action
-
10.1002/ajh.20524, 16432862
-
Liu JJ, Huang RW, Lin DJ, Wu XY, Peng J, Pan XL, Lin Q, Hou M, Zhang MH, Chen F. Antiproliferation effects of oridonin on HPB-ALL cells and its mechanisms of action. Am J Hematol 2006, 81:86-94. 10.1002/ajh.20524, 16432862.
-
(2006)
Am J Hematol
, vol.81
, pp. 86-94
-
-
Liu, J.J.1
Huang, R.W.2
Lin, D.J.3
Wu, X.Y.4
Peng, J.5
Pan, X.L.6
Lin, Q.7
Hou, M.8
Zhang, M.H.9
Chen, F.10
-
137
-
-
9444280814
-
Anti-proliferative effects of oridonin on SPC-A-1 cells and its mechanism of action
-
Liu JJ, Huang RW, Lin DJ, Peng J, Wu XY, Pan XL, Li MQ, Lin Q. Anti-proliferative effects of oridonin on SPC-A-1 cells and its mechanism of action. J Int Med Res 2004, 32:617-625.
-
(2004)
J Int Med Res
, vol.32
, pp. 617-625
-
-
Liu, J.J.1
Huang, R.W.2
Lin, D.J.3
Peng, J.4
Wu, X.Y.5
Pan, X.L.6
Li, M.Q.7
Lin, Q.8
-
138
-
-
33746326449
-
Augmentation of oridonin-induced apoptosis observed with reduced autophagy
-
10.1254/jphs.FPJ06003X, 16861822
-
Cui Q, Tashiro S, Onodera S, Ikejima T. Augmentation of oridonin-induced apoptosis observed with reduced autophagy. J Pharmacol Sci 2006, 101:230-239. 10.1254/jphs.FPJ06003X, 16861822.
-
(2006)
J Pharmacol Sci
, vol.101
, pp. 230-239
-
-
Cui, Q.1
Tashiro, S.2
Onodera, S.3
Ikejima, T.4
-
139
-
-
52949092696
-
Caspase inhibition augmented oridonin-induced cell death in murine fibrosarcoma l929 by enhancing reactive oxygen species generation
-
10.1254/jphs.FP0072079, 18818479
-
Wu JN, Huang J, Yang J, Tashiro S, Onodera S, Ikejima T. Caspase inhibition augmented oridonin-induced cell death in murine fibrosarcoma l929 by enhancing reactive oxygen species generation. J Pharmacol Sci 2008, 108:32-39. 10.1254/jphs.FP0072079, 18818479.
-
(2008)
J Pharmacol Sci
, vol.108
, pp. 32-39
-
-
Wu, J.N.1
Huang, J.2
Yang, J.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
140
-
-
77953359873
-
Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways
-
10.1016/j.canlet.2010.01.032, 20202741
-
Kang N, Zhang JH, Qiu F, Tashiro S, Onodera S, Ikejima T. Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways. Cancer Lett 2010, 294:147-158. 10.1016/j.canlet.2010.01.032, 20202741.
-
(2010)
Cancer Lett
, vol.294
, pp. 147-158
-
-
Kang, N.1
Zhang, J.H.2
Qiu, F.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
141
-
-
57049110368
-
Involvement of PKC signal pathways in oridonin-induced autophagy in HeLa cells: a protective mechanism against apoptosis
-
10.1016/j.bbrc.2008.11.038, 19026988
-
Zhang Y, Wu Y, Tashiro S, Onodera S, Ikejima T. Involvement of PKC signal pathways in oridonin-induced autophagy in HeLa cells: a protective mechanism against apoptosis. Biochem Biophys Res Commun 2009, 378:273-278. 10.1016/j.bbrc.2008.11.038, 19026988.
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 273-278
-
-
Zhang, Y.1
Wu, Y.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
142
-
-
78651264235
-
Proteomic identification of proteins involved in the anticancer activities of oridonin in HepG2 cells
-
10.1016/j.phymed.2010.06.011, 20724128
-
Wang H, Ye Y, Pan SY, Zhu GY, Li YW, Fong DW, Yu ZL. Proteomic identification of proteins involved in the anticancer activities of oridonin in HepG2 cells. Phytomedicine 2011, 18:163-169. 10.1016/j.phymed.2010.06.011, 20724128.
-
(2011)
Phytomedicine
, vol.18
, pp. 163-169
-
-
Wang, H.1
Ye, Y.2
Pan, S.Y.3
Zhu, G.Y.4
Li, Y.W.5
Fong, D.W.6
Yu, Z.L.7
-
143
-
-
77954071961
-
Induction of G(2)/M phase arrest and apoptosis by oridonin in human laryngeal carcinoma cells
-
10.1021/np9008199, 20496901
-
Kang N, Zhang JH, Qiu F, Chen S, Tashiro S, Onodera S, Ikejima T. Induction of G(2)/M phase arrest and apoptosis by oridonin in human laryngeal carcinoma cells. J Nat Prod 2010, 73:1058-1063. 10.1021/np9008199, 20496901.
-
(2010)
J Nat Prod
, vol.73
, pp. 1058-1063
-
-
Kang, N.1
Zhang, J.H.2
Qiu, F.3
Chen, S.4
Tashiro, S.5
Onodera, S.6
Ikejima, T.7
-
144
-
-
33748354274
-
Fas/FasL signaling allows extracelluar-signal regulated kinase to regulate cytochrome c release in oridonin-induced apoptotic U937 cells
-
10.1248/bpb.29.1873, 16946501
-
Liu YQ, Mu ZQ, You S, Tashiro S, Onodera S, Ikejima T. Fas/FasL signaling allows extracelluar-signal regulated kinase to regulate cytochrome c release in oridonin-induced apoptotic U937 cells. Biol Pharm Bull 2006, 29:1873-1879. 10.1248/bpb.29.1873, 16946501.
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 1873-1879
-
-
Liu, Y.Q.1
Mu, Z.Q.2
You, S.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
145
-
-
36849090058
-
Oridonin induces human epidermoid carcinoma A431 cell apoptosis through tyrosine kinase and mitochondrial pathway
-
10.1080/10286020701273866, 18058384
-
Li D, Wu LJ, Tashiro S, Onodera S, Ikejima T. Oridonin induces human epidermoid carcinoma A431 cell apoptosis through tyrosine kinase and mitochondrial pathway. J Asian Nat Prod Res 2008, 10:77-87. 10.1080/10286020701273866, 18058384.
-
(2008)
J Asian Nat Prod Res
, vol.10
, pp. 77-87
-
-
Li, D.1
Wu, L.J.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
146
-
-
0842290156
-
Oridonin induced A375-S2 cell apoptosis via bax-regulated caspase pathway activation, dependent on the cytochrome c/caspase-9 apoptosome
-
10.1080/1028602031000147375, 15008459
-
Zhang CL, Wu LJ, Tashiro S, Onodera S, Ikejima T. Oridonin induced A375-S2 cell apoptosis via bax-regulated caspase pathway activation, dependent on the cytochrome c/caspase-9 apoptosome. J Asian Nat Prod Res 2004, 6:127-138. 10.1080/1028602031000147375, 15008459.
-
(2004)
J Asian Nat Prod Res
, vol.6
, pp. 127-138
-
-
Zhang, C.L.1
Wu, L.J.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
147
-
-
7944229670
-
Cytochrome c release from oridonin-treated apoptotic A375-S2 cells is dependent on p53 and extracellular signal-regulated kinase activation
-
10.1254/jphs.FPJ04008X, 15492467
-
Zhang CL, Wu LJ, Zuo HJ, Tashiro S, Onodera S, Ikejima T. Cytochrome c release from oridonin-treated apoptotic A375-S2 cells is dependent on p53 and extracellular signal-regulated kinase activation. J Pharmacol Sci 2004, 96:155-163. 10.1254/jphs.FPJ04008X, 15492467.
-
(2004)
J Pharmacol Sci
, vol.96
, pp. 155-163
-
-
Zhang, C.L.1
Wu, L.J.2
Zuo, H.J.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
148
-
-
20244371838
-
Apoptotic effect of oridonin on NB4 cells and its mechanism
-
10.1080/10428190400019800, 16019488
-
Liu J, Huang R, Lin D, Wu X, Peng J, Lin Q, Pan X, Zhang M, Hou M, Chen F. Apoptotic effect of oridonin on NB4 cells and its mechanism. Leuk Lymphoma 2005, 46:593-597. 10.1080/10428190400019800, 16019488.
-
(2005)
Leuk Lymphoma
, vol.46
, pp. 593-597
-
-
Liu, J.1
Huang, R.2
Lin, D.3
Wu, X.4
Peng, J.5
Lin, Q.6
Pan, X.7
Zhang, M.8
Hou, M.9
Chen, F.10
-
149
-
-
18044371471
-
Oridonin induces a caspase-independent but mitochondria- and MAPK-dependent cell death in the murine fibrosarcoma cell line L929
-
10.1248/bpb.27.1527, 15467189
-
Zhang CL, Wu LJ, Tashiro S, Onodera S, Ikejima T. Oridonin induces a caspase-independent but mitochondria- and MAPK-dependent cell death in the murine fibrosarcoma cell line L929. Biol Pharm Bull 2004, 27:1527-1531. 10.1248/bpb.27.1527, 15467189.
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 1527-1531
-
-
Zhang, C.L.1
Wu, L.J.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
150
-
-
34347385839
-
P53-mediated cell cycle arrest and apoptosis through a caspase-3- independent, but caspase-9-dependent pathway in oridonin-treated MCF-7 human breast cancer cells
-
10.1111/j.1745-7254.2007.00588.x, 17588343
-
Cui Q, Yu JH, Wu JN, Tashiro S, Onodera S, Minami M, Ikejima T. P53-mediated cell cycle arrest and apoptosis through a caspase-3- independent, but caspase-9-dependent pathway in oridonin-treated MCF-7 human breast cancer cells. Acta Pharmacol Sin 2007, 28:1057-1066. 10.1111/j.1745-7254.2007.00588.x, 17588343.
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 1057-1066
-
-
Cui, Q.1
Yu, J.H.2
Wu, J.N.3
Tashiro, S.4
Onodera, S.5
Minami, M.6
Ikejima, T.7
-
151
-
-
65249128643
-
Molecular mechanisms of oridonin-induced apoptosis and autophagy in murine fibrosarcoma L929 cells
-
10.4161/auto.5.3.7896, 19202353
-
Cheng Y, Qiu F, Ikejima T. Molecular mechanisms of oridonin-induced apoptosis and autophagy in murine fibrosarcoma L929 cells. Autophagy 2009, 5:430-431. 10.4161/auto.5.3.7896, 19202353.
-
(2009)
Autophagy
, vol.5
, pp. 430-431
-
-
Cheng, Y.1
Qiu, F.2
Ikejima, T.3
-
152
-
-
70349469564
-
Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells
-
10.1016/j.abb.2009.08.011, 19699177
-
Cheng Y, Qiu F, Ye YC, Tashiro S, Onodera S, Ikejima T. Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells. Arch Biochem Biophys 2009, 490:70-75. 10.1016/j.abb.2009.08.011, 19699177.
-
(2009)
Arch Biochem Biophys
, vol.490
, pp. 70-75
-
-
Cheng, Y.1
Qiu, F.2
Ye, Y.C.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
153
-
-
49449103167
-
Oridonin induces human melanoma A375-S2 cell death partially through inhibiting insulin-like growth factor 1 receptor signaling
-
Wang HJ, Li D, Yang FY, Tashiro S, Onodera S, Ikejima T. Oridonin induces human melanoma A375-S2 cell death partially through inhibiting insulin-like growth factor 1 receptor signaling. J Asian Nat Prod Res 2008, 10:787-798.
-
(2008)
J Asian Nat Prod Res
, vol.10
, pp. 787-798
-
-
Wang, H.J.1
Li, D.2
Yang, F.Y.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
154
-
-
33846998979
-
Oridonin inhibited the tyrosine kinase activity and induced apoptosis in human epidermoid carcinoma A431 cells
-
10.1248/bpb.30.254, 17268061
-
Li D, Wu LJ, Tashiro S, Onodera S, Ikejima T. Oridonin inhibited the tyrosine kinase activity and induced apoptosis in human epidermoid carcinoma A431 cells. Biol Pharm Bull 2007, 30:254-260. 10.1248/bpb.30.254, 17268061.
-
(2007)
Biol Pharm Bull
, vol.30
, pp. 254-260
-
-
Li, D.1
Wu, L.J.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
155
-
-
18044387257
-
Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways
-
10.1158/1535-7163.MCT-04-0277, 15827331
-
Ikezoe T, Yang Y, Bandobashi K, Saito T, Takemoto S, Machida H, Togitani K, Koeffler HP, Taguchi H. Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways. Mol Cancer Ther 2005, 4:578-586. 10.1158/1535-7163.MCT-04-0277, 15827331.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 578-586
-
-
Ikezoe, T.1
Yang, Y.2
Bandobashi, K.3
Saito, T.4
Takemoto, S.5
Machida, H.6
Togitani, K.7
Koeffler, H.P.8
Taguchi, H.9
-
156
-
-
78049385776
-
Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc
-
10.1186/1471-2407-10-610, 2992521, 21054888
-
Gao FH, Hu XH, Li W, Liu H, Zhang YJ, Guo ZY, Xu MH, Wang ST, Jiang B, Liu F, Zhao YZ, Fang Y, Chen FY, Wu YL. Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc. BMC Cancer 2010, 10:610. 10.1186/1471-2407-10-610, 2992521, 21054888.
-
(2010)
BMC Cancer
, vol.10
, pp. 610
-
-
Gao, F.H.1
Hu, X.H.2
Li, W.3
Liu, H.4
Zhang, Y.J.5
Guo, Z.Y.6
Xu, M.H.7
Wang, S.T.8
Jiang, B.9
Liu, F.10
Zhao, Y.Z.11
Fang, Y.12
Chen, F.Y.13
Wu, Y.L.14
-
157
-
-
34248158083
-
Autophagy preceded apoptosis in oridonin-treated human breast cancer MCF-7 cells
-
10.1248/bpb.30.859, 17473426
-
Cui Q, Tashiro S, Onodera S, Minami M, Ikejima T. Autophagy preceded apoptosis in oridonin-treated human breast cancer MCF-7 cells. Biol Pharm Bull 2007, 30:859-864. 10.1248/bpb.30.859, 17473426.
-
(2007)
Biol Pharm Bull
, vol.30
, pp. 859-864
-
-
Cui, Q.1
Tashiro, S.2
Onodera, S.3
Minami, M.4
Ikejima, T.5
-
158
-
-
34648812757
-
Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells
-
10.1254/jphs.FPJ06022X, 17895587
-
Li D, Cui Q, Chen SG, Wu LJ, Tashiro S, Onodera S, Ikejima T. Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells. J Pharmacol Sci 2007, 105:22-33. 10.1254/jphs.FPJ06022X, 17895587.
-
(2007)
J Pharmacol Sci
, vol.105
, pp. 22-33
-
-
Li, D.1
Cui, Q.2
Chen, S.G.3
Wu, L.J.4
Tashiro, S.5
Onodera, S.6
Ikejima, T.7
-
159
-
-
69849112209
-
NF-kappab facilitates oridonin-induced apoptosis and autophagy in HT1080 cells through a p53-mediated pathway
-
10.1016/j.abb.2009.07.017, 19646415
-
Zhang Y, Wu Y, Wu D, Tashiro S, Onodera S, Ikejima T. NF-kappab facilitates oridonin-induced apoptosis and autophagy in HT1080 cells through a p53-mediated pathway. Arch Biochem Biophys 2009, 489:25-33. 10.1016/j.abb.2009.07.017, 19646415.
-
(2009)
Arch Biochem Biophys
, vol.489
, pp. 25-33
-
-
Zhang, Y.1
Wu, Y.2
Wu, D.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
160
-
-
60349085032
-
Autophagy inhibits reactive oxygen species-mediated apoptosis via activating p38-nuclear factor-kappa B survival pathways in oridonin-treated murine fibrosarcoma L929 cells
-
10.1111/j.1742-4658.2008.06864.x, 19187231
-
Cheng Y, Qiu F, Ye YC, Guo ZM, Tashiro S, Onodera S, Ikejima T. Autophagy inhibits reactive oxygen species-mediated apoptosis via activating p38-nuclear factor-kappa B survival pathways in oridonin-treated murine fibrosarcoma L929 cells. FEBS J 2009, 276:1291-1306. 10.1111/j.1742-4658.2008.06864.x, 19187231.
-
(2009)
FEBS J
, vol.276
, pp. 1291-1306
-
-
Cheng, Y.1
Qiu, F.2
Ye, Y.C.3
Guo, Z.M.4
Tashiro, S.5
Onodera, S.6
Ikejima, T.7
-
161
-
-
0023110303
-
Effects of oridonin on DNA, RNA and protein syntheses of leukemia L 1210 cells studied by autoradiography
-
Wang MY, Lin C, Zhang TM. Effects of oridonin on DNA, RNA and protein syntheses of leukemia L 1210 cells studied by autoradiography. Zhongguo Yao Li Xue Bao 1987, 8:164-165.
-
(1987)
Zhongguo Yao Li Xue Bao
, vol.8
, pp. 164-165
-
-
Wang, M.Y.1
Lin, C.2
Zhang, T.M.3
-
162
-
-
7444252185
-
Antiproliferation effects of oridonin on HL-60 cells
-
10.1007/s00277-004-0919-y, 15322762
-
Liu JJ, Wu XY, Peng J, Pan XL, Lu HL. Antiproliferation effects of oridonin on HL-60 cells. Ann Hematol 2004, 83:691-695. 10.1007/s00277-004-0919-y, 15322762.
-
(2004)
Ann Hematol
, vol.83
, pp. 691-695
-
-
Liu, J.J.1
Wu, X.Y.2
Peng, J.3
Pan, X.L.4
Lu, H.L.5
-
163
-
-
68649106338
-
In vitro and in vivo antitumor activity of oridonin nanosuspension
-
10.1016/j.ijpharm.2009.06.022, 19563872
-
Lou H, Zhang X, Gao L, Feng F, Wang J, Wei X, Yu Z, Zhang D, Zhang Q. In vitro and in vivo antitumor activity of oridonin nanosuspension. Int J Pharm 2009, 379:181-186. 10.1016/j.ijpharm.2009.06.022, 19563872.
-
(2009)
Int J Pharm
, vol.379
, pp. 181-186
-
-
Lou, H.1
Zhang, X.2
Gao, L.3
Feng, F.4
Wang, J.5
Wei, X.6
Yu, Z.7
Zhang, D.8
Zhang, Q.9
-
164
-
-
34147131374
-
Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo
-
10.1182/blood-2006-06-032250, 1852250, 17197433
-
Zhou GB, Kang H, Wang L, Gao L, Liu P, Xie J, Zhang FX, Weng XQ, Shen ZX, Chen J, Gu LJ, Yan M, Zhang DE, Chen SJ, Wang ZY, Chen Z. Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo. Blood 2007, 109:3441-3450. 10.1182/blood-2006-06-032250, 1852250, 17197433.
-
(2007)
Blood
, vol.109
, pp. 3441-3450
-
-
Zhou, G.B.1
Kang, H.2
Wang, L.3
Gao, L.4
Liu, P.5
Xie, J.6
Zhang, F.X.7
Weng, X.Q.8
Shen, Z.X.9
Chen, J.10
Gu, L.J.11
Yan, M.12
Zhang, D.E.13
Chen, S.J.14
Wang, Z.Y.15
Chen, Z.16
-
165
-
-
57949095645
-
Antiangiogenic activity of Tripterygium wilfordii and its terpenoids
-
10.1016/j.jep.2008.09.033, 18996177
-
He MF, Liu L, Ge W, Shaw PC, Jiang R, Wu LW, But PP. Antiangiogenic activity of Tripterygium wilfordii and its terpenoids. J Ethnopharmacol 2009, 121:61-68. 10.1016/j.jep.2008.09.033, 18996177.
-
(2009)
J Ethnopharmacol
, vol.121
, pp. 61-68
-
-
He, M.F.1
Liu, L.2
Ge, W.3
Shaw, P.C.4
Jiang, R.5
Wu, L.W.6
But, P.P.7
-
166
-
-
77956418436
-
Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells
-
10.1016/j.canlet.2010.05.012, 20547442
-
Li H, Takai N, Yuge A, Furukawa Y, Tsuno A, Tsukamoto Y, Kong S, Moriyama M, Narahara H. Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells. Cancer Lett 2010, 297:198-206. 10.1016/j.canlet.2010.05.012, 20547442.
-
(2010)
Cancer Lett
, vol.297
, pp. 198-206
-
-
Li, H.1
Takai, N.2
Yuge, A.3
Furukawa, Y.4
Tsuno, A.5
Tsukamoto, Y.6
Kong, S.7
Moriyama, M.8
Narahara, H.9
-
167
-
-
77957012141
-
Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells
-
10.1016/j.ejphar.2010.05.034, 20547150
-
Zhao F, Chen Y, Zeng L, Li R, Zeng R, Wen L, Liu Y, Zhang C. Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells. Eur J Pharmacol 2010, 646:1-11. 10.1016/j.ejphar.2010.05.034, 20547150.
-
(2010)
Eur J Pharmacol
, vol.646
, pp. 1-11
-
-
Zhao, F.1
Chen, Y.2
Zeng, L.3
Li, R.4
Zeng, R.5
Wen, L.6
Liu, Y.7
Zhang, C.8
-
168
-
-
78751704487
-
Biologic activity of triptolide in t(8;21) acute myeloid leukemia cells
-
10.1016/j.leukres.2010.07.013, 20691473
-
Zhou GS, Hu Z, Fang HT, Zhang FX, Pan XF, Chen XQ, Hu AM, Xu L, Zhou GB. Biologic activity of triptolide in t(8;21) acute myeloid leukemia cells. Leuk Res 2011, 35:214-218. 10.1016/j.leukres.2010.07.013, 20691473.
-
(2011)
Leuk Res
, vol.35
, pp. 214-218
-
-
Zhou, G.S.1
Hu, Z.2
Fang, H.T.3
Zhang, F.X.4
Pan, X.F.5
Chen, X.Q.6
Hu, A.M.7
Xu, L.8
Zhou, G.B.9
-
169
-
-
70449339746
-
Triptolide induces apoptosis in human anaplastic thyroid carcinoma cells by a p53-independent but NF-kappaB- related mechanism
-
Zhu W, Hu H, Qiu P, Yan G. Triptolide induces apoptosis in human anaplastic thyroid carcinoma cells by a p53-independent but NF-kappaB- related mechanism. Oncol Rep 2009, 22:1397-1401.
-
(2009)
Oncol Rep
, vol.22
, pp. 1397-1401
-
-
Zhu, W.1
Hu, H.2
Qiu, P.3
Yan, G.4
-
170
-
-
34247605460
-
Suppression of 5-lipoxygenase gene is involved in triptolide-induced apoptosis in pancreatic tumor cell lines
-
Zhou GX, Ding XL, Huang JF, Zhang H, Wu SB. Suppression of 5-lipoxygenase gene is involved in triptolide-induced apoptosis in pancreatic tumor cell lines. Biochim Biophys Acta 2007, 1770:1021-1027.
-
(2007)
Biochim Biophys Acta
, vol.1770
, pp. 1021-1027
-
-
Zhou, G.X.1
Ding, X.L.2
Huang, J.F.3
Zhang, H.4
Wu, S.B.5
-
171
-
-
77956901995
-
Triptolide and TRAIL combination enhances apoptosis in cholangiocarcinoma
-
10.1016/j.jss.2010.03.067, 20691980
-
Clawson KA, Borja-Cacho D, Antonoff MB, Saluja AK, Vickers SM. Triptolide and TRAIL combination enhances apoptosis in cholangiocarcinoma. J Surg Res 2010, 163:244-249. 10.1016/j.jss.2010.03.067, 20691980.
-
(2010)
J Surg Res
, vol.163
, pp. 244-249
-
-
Clawson, K.A.1
Borja-Cacho, D.2
Antonoff, M.B.3
Saluja, A.K.4
Vickers, S.M.5
-
172
-
-
33745944185
-
Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells
-
10.1182/blood-2005-09-3898, 1895484, 16556893
-
Carter BZ, Mak DH, Schober WD, McQueen T, Harris D, Estrov Z, Evans RL, Andreeff M. Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells. Blood 2006, 108:630-637. 10.1182/blood-2005-09-3898, 1895484, 16556893.
-
(2006)
Blood
, vol.108
, pp. 630-637
-
-
Carter, B.Z.1
Mak, D.H.2
Schober, W.D.3
McQueen, T.4
Harris, D.5
Estrov, Z.6
Evans, R.L.7
Andreeff, M.8
-
173
-
-
34250869896
-
Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-deficient HL-60 cells
-
10.1016/j.canlet.2005.10.001, 16316721
-
Wan CK, Wang C, Cheung HY, Yang M, Fong WF. Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-deficient HL-60 cells. Cancer Lett 2006, 241:31-41. 10.1016/j.canlet.2005.10.001, 16316721.
-
(2006)
Cancer Lett
, vol.241
, pp. 31-41
-
-
Wan, C.K.1
Wang, C.2
Cheung, H.Y.3
Yang, M.4
Fong, W.F.5
-
174
-
-
79955831016
-
Triptolide Inhibits Proliferation and Migration of Colon Cancer Cells by Inhibition of Cell Cycle Regulators and Cytokine Receptors
-
10.1016/j.jss.2009.07.002, 19922946
-
Johnson SM, Wang X, Mark Evers B. Triptolide Inhibits Proliferation and Migration of Colon Cancer Cells by Inhibition of Cell Cycle Regulators and Cytokine Receptors. J Surg Res 2011, 168:197-205. 10.1016/j.jss.2009.07.002, 19922946.
-
(2011)
J Surg Res
, vol.168
, pp. 197-205
-
-
Johnson, S.M.1
Wang, X.2
Mark Evers, B.3
-
175
-
-
35349011081
-
Triptolide inhibits tumor promoter-induced uPAR expression via blocking NF-kappaB signaling in human gastric AGS cells
-
Chang HJ, Kim MH, Baek MK, Park JS, Chung IJ, Shin BA, Ahn BW, Jung YD. Triptolide inhibits tumor promoter-induced uPAR expression via blocking NF-kappaB signaling in human gastric AGS cells. Anticancer Res 2007, 27:3411-3417.
-
(2007)
Anticancer Res
, vol.27
, pp. 3411-3417
-
-
Chang, H.J.1
Kim, M.H.2
Baek, M.K.3
Park, J.S.4
Chung, I.J.5
Shin, B.A.6
Ahn, B.W.7
Jung, Y.D.8
-
176
-
-
76049110182
-
Anti-angiogenic activity of triptolide in anaplastic thyroid carcinoma is mediated by targeting vascular endothelial and tumor cells
-
10.1016/j.vph.2009.10.006, 19854299
-
Zhu W, He S, Li Y, Qiu P, Shu M, Ou Y, Zhou Y, Leng T, Xie J, Zheng X, Xu D, Su X, Yan G. Anti-angiogenic activity of triptolide in anaplastic thyroid carcinoma is mediated by targeting vascular endothelial and tumor cells. Vascul Pharmacol 2010, 52:46-54. 10.1016/j.vph.2009.10.006, 19854299.
-
(2010)
Vascul Pharmacol
, vol.52
, pp. 46-54
-
-
Zhu, W.1
He, S.2
Li, Y.3
Qiu, P.4
Shu, M.5
Ou, Y.6
Zhou, Y.7
Leng, T.8
Xie, J.9
Zheng, X.10
Xu, D.11
Su, X.12
Yan, G.13
-
177
-
-
52149116029
-
Triptolide inhibits interferon-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells
-
10.1016/j.canlet.2008.05.025, 18572307
-
Liang M, Fu J. Triptolide inhibits interferon-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells. Cancer Lett 2008, 270:337-341. 10.1016/j.canlet.2008.05.025, 18572307.
-
(2008)
Cancer Lett
, vol.270
, pp. 337-341
-
-
Liang, M.1
Fu, J.2
-
178
-
-
0141576565
-
Triptolide inhibits the growth and metastasis of solid tumors
-
Yang S, Chen J, Guo Z, Xu XM, Wang L, Pei XF, Yang J, Underhill CB, Zhang L. Triptolide inhibits the growth and metastasis of solid tumors. Mol Cancer Ther 2003, 2:65-72.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 65-72
-
-
Yang, S.1
Chen, J.2
Guo, Z.3
Xu, X.M.4
Wang, L.5
Pei, X.F.6
Yang, J.7
Underhill, C.B.8
Zhang, L.9
-
179
-
-
33750282749
-
Inhibitory effect of triptolide on lymph node metastasis in patients with non-Hodgkin lymphoma by regulating SDF-1/CXCR4 axis in vitro
-
10.1111/j.1745-7254.2006.00415.x, 17049119
-
Zhang C, Cui GH, Liu F, Wu QL, Chen Y. Inhibitory effect of triptolide on lymph node metastasis in patients with non-Hodgkin lymphoma by regulating SDF-1/CXCR4 axis in vitro. Acta pharmacologica Sinica 2006, 27:1438-1446. 10.1111/j.1745-7254.2006.00415.x, 17049119.
-
(2006)
Acta pharmacologica Sinica
, vol.27
, pp. 1438-1446
-
-
Zhang, C.1
Cui, G.H.2
Liu, F.3
Wu, Q.L.4
Chen, Y.5
-
180
-
-
34249092004
-
Synergistic effect of triptolide combined with 5-fluorouracil on colon carcinoma
-
10.1136/pgmj.2006.055426, 2600066, 17488865
-
Tang XY, Zhu YQ, Tao WH, Wei B, Lin XL. Synergistic effect of triptolide combined with 5-fluorouracil on colon carcinoma. Postgrad Med J 2007, 83:338-343. 10.1136/pgmj.2006.055426, 2600066, 17488865.
-
(2007)
Postgrad Med J
, vol.83
, pp. 338-343
-
-
Tang, X.Y.1
Zhu, Y.Q.2
Tao, W.H.3
Wei, B.4
Lin, X.L.5
-
181
-
-
78751528792
-
In vitro synergistic cytotoxic effect of triptolide combined with hydroxycamptothecin on pancreatic cancer cells
-
10.1142/S0192415X11008695, 21213403
-
Yang SW, Wang W, Xie XY, Zhu WP, Li FQ. In vitro synergistic cytotoxic effect of triptolide combined with hydroxycamptothecin on pancreatic cancer cells. Am J Chin Med 2011, 39:121-134. 10.1142/S0192415X11008695, 21213403.
-
(2011)
Am J Chin Med
, vol.39
, pp. 121-134
-
-
Yang, S.W.1
Wang, W.2
Xie, X.Y.3
Zhu, W.P.4
Li, F.Q.5
-
182
-
-
55549091687
-
Triptolide cooperates with chemotherapy to induce apoptosis in acute myeloid leukemia cells
-
10.1016/j.exphem.2008.08.002, 18922616
-
Pigneux A, Mahon FX, Uhalde M, Jeanneteau M, Lacombe F, Milpied N, Reiffers J, Belloc F. Triptolide cooperates with chemotherapy to induce apoptosis in acute myeloid leukemia cells. Exp Hematol 2008, 36:1648-1659. 10.1016/j.exphem.2008.08.002, 18922616.
-
(2008)
Exp Hematol
, vol.36
, pp. 1648-1659
-
-
Pigneux, A.1
Mahon, F.X.2
Uhalde, M.3
Jeanneteau, M.4
Lacombe, F.5
Milpied, N.6
Reiffers, J.7
Belloc, F.8
-
183
-
-
43549107334
-
Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5
-
10.1182/blood-2007-05-091504, 2275030, 18187663
-
Carter BZ, Mak DH, Schober WD, Dietrich MF, Pinilla C, Vassilev LT, Reed JC, Andreeff M. Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5. Blood 2008, 111:3742-3750. 10.1182/blood-2007-05-091504, 2275030, 18187663.
-
(2008)
Blood
, vol.111
, pp. 3742-3750
-
-
Carter, B.Z.1
Mak, D.H.2
Schober, W.D.3
Dietrich, M.F.4
Pinilla, C.5
Vassilev, L.T.6
Reed, J.C.7
Andreeff, M.8
-
184
-
-
34548061783
-
Enhanced antitumor effect of combined triptolide and ionizing radiation
-
10.1158/1078-0432.CCR-07-0416, 17699869
-
Wang W, Yang S, Su Y, Xiao Z, Wang C, Li X, Lin L, Fenton BM, Paoni SF, Ding I, Keng P, Okunieff P, Zhang L. Enhanced antitumor effect of combined triptolide and ionizing radiation. Clin Cancer Res 2007, 13:4891-4899. 10.1158/1078-0432.CCR-07-0416, 17699869.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4891-4899
-
-
Wang, W.1
Yang, S.2
Su, Y.3
Xiao, Z.4
Wang, C.5
Li, X.6
Lin, L.7
Fenton, B.M.8
Paoni, S.F.9
Ding, I.10
Keng, P.11
Okunieff, P.12
Zhang, L.13
-
185
-
-
77149131832
-
Effects of ursolic acid on the proliferation and apoptosis of human ovarian cancer cells
-
Wang X, Li L, Wang B, Xiang J. Effects of ursolic acid on the proliferation and apoptosis of human ovarian cancer cells. J Huazhong Uni Sci Technol Med Sci 2009, 29:761-764.
-
(2009)
J Huazhong Uni Sci Technol Med Sci
, vol.29
, pp. 761-764
-
-
Wang, X.1
Li, L.2
Wang, B.3
Xiang, J.4
-
186
-
-
77956941684
-
Ursolic acid induces doxorubicin-resistant HepG2 cell death via the release of apoptosis-inducing factor
-
10.1016/j.canlet.2010.06.010, 20630652
-
Yang L, Liu X, Lu Z, Yuet-Wa Chan J, Zhou L, Fung KP, Wu P, Wu S. Ursolic acid induces doxorubicin-resistant HepG2 cell death via the release of apoptosis-inducing factor. Cancer Lett 2010, 298:128-138. 10.1016/j.canlet.2010.06.010, 20630652.
-
(2010)
Cancer Lett
, vol.298
, pp. 128-138
-
-
Yang, L.1
Liu, X.2
Lu, Z.3
Yuet-Wa Chan, J.4
Zhou, L.5
Fung, K.P.6
Wu, P.7
Wu, S.8
-
187
-
-
78249242752
-
Antitumor effects of ursolic acid in a mouse model of postmenopausal breast cancer
-
10.1080/01635581.2010.492092, 21058195
-
De Angel RE, Smith SM, Glickman RD, Perkins SN, Hursting SD. Antitumor effects of ursolic acid in a mouse model of postmenopausal breast cancer. Nutr Cancer 2010, 62:1074-1086. 10.1080/01635581.2010.492092, 21058195.
-
(2010)
Nutr Cancer
, vol.62
, pp. 1074-1086
-
-
De Angel, R.E.1
Smith, S.M.2
Glickman, R.D.3
Perkins, S.N.4
Hursting, S.D.5
-
188
-
-
77954267414
-
Synthesis and in vitro cytotoxicity of novel ursolic acid derivatives
-
Meng Y, Song Y, Yan Z, Xia Y. Synthesis and in vitro cytotoxicity of novel ursolic acid derivatives. Molecules (Basel, Switzerland) 2010, 15:4033-4040.
-
(2010)
Molecules (Basel, Switzerland)
, vol.15
, pp. 4033-4040
-
-
Meng, Y.1
Song, Y.2
Yan, Z.3
Xia, Y.4
-
189
-
-
77958049067
-
Apoptotic action of ursolic acid isolated from Corni fructus in RC-58T/h/SA#4 primary human prostate cancer cells
-
10.1016/j.bmcl.2010.09.073, 20943386
-
Kwon SH, Park HY, Kim JY, Jeong IY, Lee MK, Seo KI. Apoptotic action of ursolic acid isolated from Corni fructus in RC-58T/h/SA#4 primary human prostate cancer cells. Bioorg Med Chem Lett 2010, 20:6435-6438. 10.1016/j.bmcl.2010.09.073, 20943386.
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 6435-6438
-
-
Kwon, S.H.1
Park, H.Y.2
Kim, J.Y.3
Jeong, I.Y.4
Lee, M.K.5
Seo, K.I.6
-
190
-
-
77951660302
-
Ursolic acid induces PC-3 cell apoptosis via activation of JNK and inhibition of Akt pathways in vitro
-
Zhang Y, Kong C, Zeng Y, Wang L, Li Z, Wang H, Xu C, Sun Y. Ursolic acid induces PC-3 cell apoptosis via activation of JNK and inhibition of Akt pathways in vitro. Mol Carcinog 2010, 49:374-385.
-
(2010)
Mol Carcinog
, vol.49
, pp. 374-385
-
-
Zhang, Y.1
Kong, C.2
Zeng, Y.3
Wang, L.4
Li, Z.5
Wang, H.6
Xu, C.7
Sun, Y.8
-
191
-
-
77952625527
-
Ursolic acid, a naturally occurring triterpenoid, suppresses migration and invasion of human breast cancer cells by modulating c-Jun N-terminal kinase, Akt and mammalian target of rapamycin signaling
-
10.1002/mnfr.200900414, 20352621
-
Yeh CT, Wu CH, Yen GC. Ursolic acid, a naturally occurring triterpenoid, suppresses migration and invasion of human breast cancer cells by modulating c-Jun N-terminal kinase, Akt and mammalian target of rapamycin signaling. Mol Nutr Food Res 2010, 54:1285-1295. 10.1002/mnfr.200900414, 20352621.
-
(2010)
Mol Nutr Food Res
, vol.54
, pp. 1285-1295
-
-
Yeh, C.T.1
Wu, C.H.2
Yen, G.C.3
-
192
-
-
65749102893
-
Ursolic acid inhibits IL-1beta or TNF-alpha-induced C6 glioma invasion through suppressing the association ZIP/p62 with PKC-zeta and downregulating the MMP-9 expression
-
10.1002/mc.20490, 18973186
-
Huang HC, Huang CY, Lin-Shiau SY, Lin JK. Ursolic acid inhibits IL-1beta or TNF-alpha-induced C6 glioma invasion through suppressing the association ZIP/p62 with PKC-zeta and downregulating the MMP-9 expression. Mol Carcinog 2009, 48:517-531. 10.1002/mc.20490, 18973186.
-
(2009)
Mol Carcinog
, vol.48
, pp. 517-531
-
-
Huang, H.C.1
Huang, C.Y.2
Lin-Shiau, S.Y.3
Lin, J.K.4
-
193
-
-
77954203666
-
Antiangiogenic activity of ursolic acid
-
10.1177/1534735410367647, 20462855
-
Kanjoormana M, Kuttan G. Antiangiogenic activity of ursolic acid. Integr Cancer Ther 2010, 9:224-235. 10.1177/1534735410367647, 20462855.
-
(2010)
Integr Cancer Ther
, vol.9
, pp. 224-235
-
-
Kanjoormana, M.1
Kuttan, G.2
-
194
-
-
78751497839
-
Antiangiogenic Potential of Three Triterpenic Acids in Human Liver Cancer Cells
-
Lin CC, Huang CY, Mong MC, Chan CY, Yin MC. Antiangiogenic Potential of Three Triterpenic Acids in Human Liver Cancer Cells. J Agric Food Chem 2010, 755-762.
-
(2010)
J Agric Food Chem
, pp. 755-762
-
-
Lin, C.C.1
Huang, C.Y.2
Mong, M.C.3
Chan, C.Y.4
Yin, M.C.5
-
195
-
-
1642545128
-
P53-mediated cell cycle arrest and apoptosis induced by shikonin via a caspase-9-dependent mechanism in human malignant melanoma A375-S2 cells
-
10.1254/jphs.94.166, 14978355
-
Wu Z, Wu L, Li L, Tashiro S, Onodera S, Ikejima T. p53-mediated cell cycle arrest and apoptosis induced by shikonin via a caspase-9-dependent mechanism in human malignant melanoma A375-S2 cells. J Pharmacol Sci 2004, 94:166-176. 10.1254/jphs.94.166, 14978355.
-
(2004)
J Pharmacol Sci
, vol.94
, pp. 166-176
-
-
Wu, Z.1
Wu, L.2
Li, L.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
196
-
-
3042636192
-
Shikonin regulates HeLa cell death via caspase-3 activation and blockage of DNA synthesis
-
10.1080/1028602032000169622, 15224412
-
Wu Z, Wu LJ, Li LH, Tashiro S, Onodera S, Ikejima T. Shikonin regulates HeLa cell death via caspase-3 activation and blockage of DNA synthesis. J Asian Nat Prod Res 2004, 6:155-166. 10.1080/1028602032000169622, 15224412.
-
(2004)
J Asian Nat Prod Res
, vol.6
, pp. 155-166
-
-
Wu, Z.1
Wu, L.J.2
Li, L.H.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
197
-
-
37349073187
-
Shikonin-induced apoptosis involves caspase-3 activity in a human bladder cancer cell line (T24)
-
Yeh CC, Kuo HM, Li TM, Lin JP, Yu FS, Lu HF, Chung JG, Yang JS. Shikonin-induced apoptosis involves caspase-3 activity in a human bladder cancer cell line (T24). In Vivo 2007, 21:1011-1019.
-
(2007)
In Vivo
, vol.21
, pp. 1011-1019
-
-
Yeh, C.C.1
Kuo, H.M.2
Li, T.M.3
Lin, J.P.4
Yu, F.S.5
Lu, H.F.6
Chung, J.G.7
Yang, J.S.8
-
198
-
-
0032796797
-
Shikonin, an ingredient of Lithospermum erythrorhizon induced apoptosis in HL60 human premyelocytic leukemia cell line
-
10.1055/s-1999-14010, 10483373
-
Yoon Y, Kim YO, Lim NY, Jeon WK, Sung HJ. Shikonin, an ingredient of Lithospermum erythrorhizon induced apoptosis in HL60 human premyelocytic leukemia cell line. Planta Med 1999, 65:532-535. 10.1055/s-1999-14010, 10483373.
-
(1999)
Planta Med
, vol.65
, pp. 532-535
-
-
Yoon, Y.1
Kim, Y.O.2
Lim, N.Y.3
Jeon, W.K.4
Sung, H.J.5
-
199
-
-
34250748014
-
Shikonin circumvents cancer drug resistance by induction of a necroptotic death
-
10.1158/1535-7163.MCT-06-0511, 17513612
-
Han W, Li L, Qiu S, Lu Q, Pan Q, Gu Y, Luo J, Hu X. Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Mol Cancer Ther 2007, 6:1641-1649. 10.1158/1535-7163.MCT-06-0511, 17513612.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1641-1649
-
-
Han, W.1
Li, L.2
Qiu, S.3
Lu, Q.4
Pan, Q.5
Gu, Y.6
Luo, J.7
Hu, X.8
-
200
-
-
67349269527
-
Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis
-
10.1007/s10495-009-0334-x, 19288276
-
Han W, Xie J, Li L, Liu Z, Hu X. Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis. Apoptosis 2009, 14:674-686. 10.1007/s10495-009-0334-x, 19288276.
-
(2009)
Apoptosis
, vol.14
, pp. 674-686
-
-
Han, W.1
Xie, J.2
Li, L.3
Liu, Z.4
Hu, X.5
-
201
-
-
40849147137
-
Growth inhibition and induction of apoptosis in human oral squamous cell carcinoma Tca-8113 cell lines by Shikonin was partly through the inactivation of NF-kappaB pathway
-
10.1002/ptr.2340, 18167055
-
Min R, Tong J, Wenjun Y, Wenhu D, Xiaojian Z, Jiacai H, Jian Z, Wantao C, Chenping Z. Growth inhibition and induction of apoptosis in human oral squamous cell carcinoma Tca-8113 cell lines by Shikonin was partly through the inactivation of NF-kappaB pathway. Phytother Res 2008, 22:407-415. 10.1002/ptr.2340, 18167055.
-
(2008)
Phytother Res
, vol.22
, pp. 407-415
-
-
Min, R.1
Tong, J.2
Wenjun, Y.3
Wenhu, D.4
Xiaojian, Z.5
Jiacai, H.6
Jian, Z.7
Wantao, C.8
Chenping, Z.9
-
202
-
-
78650243853
-
Shikonin inhibits the proliferation and induces the apoptosis of human HepG2 cells
-
Nie YK, Zhu LS, Yu HM. Shikonin inhibits the proliferation and induces the apoptosis of human HepG2 cells. Can J Physiol Pharm 2010, 88:1138-1146.
-
(2010)
Can J Physiol Pharm
, vol.88
, pp. 1138-1146
-
-
Nie, Y.K.1
Zhu, L.S.2
Yu, H.M.3
-
203
-
-
77952397814
-
Shikonin Induces Apoptosis through Reactive Oxygen Species/Extracellular Signal- Regulated Kinase Pathway in Osteosarcoma Cells
-
10.1248/bpb.33.816, 20460760
-
Chang IC, Huang YJ, Chiang TI, Yeh CW, Hsu LS. Shikonin Induces Apoptosis through Reactive Oxygen Species/Extracellular Signal- Regulated Kinase Pathway in Osteosarcoma Cells. Biol Pharm Bull 2010, 33:816-824. 10.1248/bpb.33.816, 20460760.
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 816-824
-
-
Chang, I.C.1
Huang, Y.J.2
Chiang, T.I.3
Yeh, C.W.4
Hsu, L.S.5
-
204
-
-
49149088537
-
Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells
-
10.1038/cr.2008.86, 18663379
-
Mao X, Yu CR, Li WH, Li WX. Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells. Cell Res 2008, 18:879-888. 10.1038/cr.2008.86, 18663379.
-
(2008)
Cell Res
, vol.18
, pp. 879-888
-
-
Mao, X.1
Yu, C.R.2
Li, W.H.3
Li, W.X.4
-
205
-
-
64249097600
-
Shikonin exerts antitumor activity via proteasome inhibition and cell death induction in vitro and in vivo
-
10.1002/ijc.24195, 2707765, 19165859
-
Yang H, Zhou P, Huang H, Chen D, Ma N, Cui QC, Shen S, Dong W, Zhang X, Lian W, Wang X, Dou QP, Liu J. Shikonin exerts antitumor activity via proteasome inhibition and cell death induction in vitro and in vivo. Int J Cancer 2009, 124:2450-2459. 10.1002/ijc.24195, 2707765, 19165859.
-
(2009)
Int J Cancer
, vol.124
, pp. 2450-2459
-
-
Yang, H.1
Zhou, P.2
Huang, H.3
Chen, D.4
Ma, N.5
Cui, Q.C.6
Shen, S.7
Dong, W.8
Zhang, X.9
Lian, W.10
Wang, X.11
Dou, Q.P.12
Liu, J.13
-
206
-
-
33746377985
-
SH-7, a new synthesized shikonin derivative, exerting its potent antitumor activities as a topoisomerase inhibitor
-
10.1002/ijc.21943, 16570288
-
Yang F, Chen Y, Duan W, Zhang C, Zhu H, Ding J. SH-7, a new synthesized shikonin derivative, exerting its potent antitumor activities as a topoisomerase inhibitor. Int J Cancer 2006, 119:1184-1193. 10.1002/ijc.21943, 16570288.
-
(2006)
Int J Cancer
, vol.119
, pp. 1184-1193
-
-
Yang, F.1
Chen, Y.2
Duan, W.3
Zhang, C.4
Zhu, H.5
Ding, J.6
-
207
-
-
77951297556
-
A novel antiestrogen agent Shikonin inhibits estrogen- dependent gene transcription in human breast cancer cells
-
Yao Y, Zhou Q. A novel antiestrogen agent Shikonin inhibits estrogen- dependent gene transcription in human breast cancer cells. Breast Cancer Res Tr 2010, 121:233-240.
-
(2010)
Breast Cancer Res Tr
, vol.121
, pp. 233-240
-
-
Yao, Y.1
Zhou, Q.2
-
208
-
-
78649320545
-
Inhibition of estrogen signaling activates the NRF2 pathway in breast cancer
-
Yao YA, Brodie AMH, Davidson NE, Kensler TW, Zhou Q. Inhibition of estrogen signaling activates the NRF2 pathway in breast cancer. Breast Cancer Res Tr 2010, 124:585-591.
-
(2010)
Breast Cancer Res Tr
, vol.124
, pp. 585-591
-
-
Yao, Y.A.1
Brodie, A.M.H.2
Davidson, N.E.3
Kensler, T.W.4
Zhou, Q.5
-
209
-
-
79953756477
-
Shikonin inhibits tumor invasion via down-regulation of NF-kappaB-mediated MMP-9 expression in human ACC-M cells
-
10.1111/j.1601-0825.2010.01758.x, 21029262
-
Min R, Zun Z, Min Y, Wenhu D, Wenjun Y, Chenping Z. Shikonin inhibits tumor invasion via down-regulation of NF-kappaB-mediated MMP-9 expression in human ACC-M cells. Oral Dis 2011, 17:362-369. 10.1111/j.1601-0825.2010.01758.x, 21029262.
-
(2011)
Oral Dis
, vol.17
, pp. 362-369
-
-
Min, R.1
Zun, Z.2
Min, Y.3
Wenhu, D.4
Wenjun, Y.5
Chenping, Z.6
-
210
-
-
41549168703
-
Ultrasonic extraction and separation of anthraquinones from Rheum palmatum L
-
10.1016/j.ultsonch.2007.12.008, 18280764
-
Wang L, Li D, Bao C, You J, Wang Z, Shi Y, Zhang H. Ultrasonic extraction and separation of anthraquinones from Rheum palmatum L. Ultrason Sonochem 2008, 15:738-746. 10.1016/j.ultsonch.2007.12.008, 18280764.
-
(2008)
Ultrason Sonochem
, vol.15
, pp. 738-746
-
-
Wang, L.1
Li, D.2
Bao, C.3
You, J.4
Wang, Z.5
Shi, Y.6
Zhang, H.7
-
211
-
-
34548049994
-
Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent
-
10.1002/med.20095, 17019678
-
Srinivas G, Babykutty S, Sathiadevan PP, Srinivas P. Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent. Med Res Rev 2007, 27:591-608. 10.1002/med.20095, 17019678.
-
(2007)
Med Res Rev
, vol.27
, pp. 591-608
-
-
Srinivas, G.1
Babykutty, S.2
Sathiadevan, P.P.3
Srinivas, P.4
-
212
-
-
73449090077
-
Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo
-
10.1016/j.ejphar.2009.10.035, 19857484
-
Chun-Guang W, Jun-Qing Y, Bei-Zhong L, Dan-Ting J, Chong W, Liang Z, Dan Z, Yan W. Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo. Eur J Pharmacol 2010, 627:33-41. 10.1016/j.ejphar.2009.10.035, 19857484.
-
(2010)
Eur J Pharmacol
, vol.627
, pp. 33-41
-
-
Chun-Guang, W.1
Jun-Qing, Y.2
Bei-Zhong, L.3
Dan-Ting, J.4
Chong, W.5
Liang, Z.6
Dan, Z.7
Yan, W.8
-
213
-
-
34147152865
-
Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor
-
Muto A, Hori M, Sasaki Y, Saitoh A, Yasuda I, Maekawa T, Uchida T, Asakura K, Nakazato T, Kaneda T, Kizaki M, Ikeda Y, Yoshida T. Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor. Mol Cancer Ther 2007, 6:987-994.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 987-994
-
-
Muto, A.1
Hori, M.2
Sasaki, Y.3
Saitoh, A.4
Yasuda, I.5
Maekawa, T.6
Uchida, T.7
Asakura, K.8
Nakazato, T.9
Kaneda, T.10
Kizaki, M.11
Ikeda, Y.12
Yoshida, T.13
-
214
-
-
20444505248
-
Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway
-
10.1016/j.bcp.2005.04.026, 15941563
-
Su YT, Chang HL, Shyue SK, Hsu SL. Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. Biochem Pharmacol 2005, 70:229-241. 10.1016/j.bcp.2005.04.026, 15941563.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 229-241
-
-
Su, Y.T.1
Chang, H.L.2
Shyue, S.K.3
Hsu, S.L.4
-
215
-
-
16844386205
-
Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth
-
10.1158/0008-5472.CAN-04-3250, 15781642
-
Cha TL, Qiu L, Chen CT, Wen Y, Hung MC. Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth. Cancer Res 2005, 65:2287-2295. 10.1158/0008-5472.CAN-04-3250, 15781642.
-
(2005)
Cancer Res
, vol.65
, pp. 2287-2295
-
-
Cha, T.L.1
Qiu, L.2
Chen, C.T.3
Wen, Y.4
Hung, M.C.5
-
216
-
-
78549231954
-
Emodin triggers DNA double-strand breaks by stabilizing topoisomerase II-DNA cleavage complexes and by inhibiting ATP hydrolysis of topoisomerase II
-
10.1093/toxsci/kfq282, 20855424
-
Li Y, Luan Y, Qi X, Li M, Gong L, Xue X, Wu X, Wu Y, Chen M, Xing G, Yao J, Ren J. Emodin triggers DNA double-strand breaks by stabilizing topoisomerase II-DNA cleavage complexes and by inhibiting ATP hydrolysis of topoisomerase II. Toxicol Sci 2010, 118:435-443. 10.1093/toxsci/kfq282, 20855424.
-
(2010)
Toxicol Sci
, vol.118
, pp. 435-443
-
-
Li, Y.1
Luan, Y.2
Qi, X.3
Li, M.4
Gong, L.5
Xue, X.6
Wu, X.7
Wu, Y.8
Chen, M.9
Xing, G.10
Yao, J.11
Ren, J.12
-
217
-
-
71349083599
-
Suppression of ERCC1 and Rad51 expression through ERK1/2 inactivation is essential in emodin-mediated cytotoxicity in human non-small cell lung cancer cells
-
10.1016/j.bcp.2009.09.024, 19799875
-
Ko JC, Su YJ, Lin ST, Jhan JY, Ciou SC, Cheng CM, Lin YW. Suppression of ERCC1 and Rad51 expression through ERK1/2 inactivation is essential in emodin-mediated cytotoxicity in human non-small cell lung cancer cells. Biochem Pharmacol 2010, 79:655-664. 10.1016/j.bcp.2009.09.024, 19799875.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 655-664
-
-
Ko, J.C.1
Su, Y.J.2
Lin, S.T.3
Jhan, J.Y.4
Ciou, S.C.5
Cheng, C.M.6
Lin, Y.W.7
-
218
-
-
33646337670
-
Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation
-
10.1002/ijc.21641, 16388516
-
Kwak HJ, Park MJ, Park CM, Moon SI, Yoo DH, Lee HC, Lee SH, Kim MS, Lee HW, Shin WS, Park IC, Rhee CH, Hong SI. Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation. Int J Cancer 2006, 118:2711-2720. 10.1002/ijc.21641, 16388516.
-
(2006)
Int J Cancer
, vol.118
, pp. 2711-2720
-
-
Kwak, H.J.1
Park, M.J.2
Park, C.M.3
Moon, S.I.4
Yoo, D.H.5
Lee, H.C.6
Lee, S.H.7
Kim, M.S.8
Lee, H.W.9
Shin, W.S.10
Park, I.C.11
Rhee, C.H.12
Hong, S.I.13
-
219
-
-
20944445254
-
Emodin inhibits tumor cell migration through suppression of the phosphatidylinositol 3-kinase-Cdc42/Rac1 pathway
-
10.1007/s00018-005-5050-2, 15928809
-
Huang Q, Shen HM, Ong CN. Emodin inhibits tumor cell migration through suppression of the phosphatidylinositol 3-kinase-Cdc42/Rac1 pathway. Cell Mol Life Sci 2005, 62:1167-1175. 10.1007/s00018-005-5050-2, 15928809.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 1167-1175
-
-
Huang, Q.1
Shen, H.M.2
Ong, C.N.3
-
220
-
-
33745231161
-
Emodin inhibits tumor cell adhesion through disruption of the membrane lipid Raft-associated integrin signaling pathway
-
10.1158/0008-5472.CAN-06-0077, 16740720
-
Huang Q, Shen HM, Shui G, Wenk MR, Ong CN. Emodin inhibits tumor cell adhesion through disruption of the membrane lipid Raft-associated integrin signaling pathway. Cancer Res 2006, 66:5807-5815. 10.1158/0008-5472.CAN-06-0077, 16740720.
-
(2006)
Cancer Res
, vol.66
, pp. 5807-5815
-
-
Huang, Q.1
Shen, H.M.2
Shui, G.3
Wenk, M.R.4
Ong, C.N.5
-
221
-
-
27244437283
-
Gene expression alteration during redox-dependent enhancement of arsenic cytotoxicity by emodin in HeLa cells
-
10.1038/sj.cr.7290321, 16045814
-
Wang XJ, Yang J, Cang H, Zou YQ, Yi J. Gene expression alteration during redox-dependent enhancement of arsenic cytotoxicity by emodin in HeLa cells. Cell Res 2005, 15:511-522. 10.1038/sj.cr.7290321, 16045814.
-
(2005)
Cell Res
, vol.15
, pp. 511-522
-
-
Wang, X.J.1
Yang, J.2
Cang, H.3
Zou, Y.Q.4
Yi, J.5
-
222
-
-
38649089487
-
Emodin-induced generation of reactive oxygen species inhibits RhoA activation to sensitize gastric carcinoma cells to anoikis
-
10.1593/neo.07754, 2213898, 18231637
-
Cai J, Niu X, Chen Y, Hu Q, Shi G, Wu H, Wang J, Yi J. Emodin-induced generation of reactive oxygen species inhibits RhoA activation to sensitize gastric carcinoma cells to anoikis. Neoplasia 2008, 10:41-51. 10.1593/neo.07754, 2213898, 18231637.
-
(2008)
Neoplasia
, vol.10
, pp. 41-51
-
-
Cai, J.1
Niu, X.2
Chen, Y.3
Hu, Q.4
Shi, G.5
Wu, H.6
Wang, J.7
Yi, J.8
-
223
-
-
45349099696
-
Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: the mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1
-
10.4161/cbt.7.3.5457, 18285700
-
Huang XZ, Wang J, Huang C, Chen YY, Shi GY, Hu QS, Yi J. Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: the mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1. Cancer Biol Ther 2008, 7:468-475. 10.4161/cbt.7.3.5457, 18285700.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 468-475
-
-
Huang, X.Z.1
Wang, J.2
Huang, C.3
Chen, Y.Y.4
Shi, G.Y.5
Hu, Q.S.6
Yi, J.7
-
224
-
-
77249157217
-
Emodin enhances sensitivity of gallbladder cancer cells to platinum drugs via glutathion depletion and MRP1 downregulation
-
10.1016/j.bcp.2009.12.006, 20005210
-
Wang W, Sun YP, Huang XZ, He M, Chen YY, Shi GY, Li H, Yi J, Wang J. Emodin enhances sensitivity of gallbladder cancer cells to platinum drugs via glutathion depletion and MRP1 downregulation. Biochem Pharmacol 2010, 79:1134-1140. 10.1016/j.bcp.2009.12.006, 20005210.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 1134-1140
-
-
Wang, W.1
Sun, Y.P.2
Huang, X.Z.3
He, M.4
Chen, Y.Y.5
Shi, G.Y.6
Li, H.7
Yi, J.8
Wang, J.9
-
225
-
-
67651045814
-
Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation
-
10.1016/j.yexcr.2009.06.002, 19505457
-
Chen RS, Jhan JY, Su YJ, Lee WT, Cheng CM, Ciou SC, Lin ST, Chuang SM, Ko JC, Lin YW. Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation. Exp Cell Res 2009, 315:2658-2672. 10.1016/j.yexcr.2009.06.002, 19505457.
-
(2009)
Exp Cell Res
, vol.315
, pp. 2658-2672
-
-
Chen, R.S.1
Jhan, J.Y.2
Su, Y.J.3
Lee, W.T.4
Cheng, C.M.5
Ciou, S.C.6
Lin, S.T.7
Chuang, S.M.8
Ko, J.C.9
Lin, Y.W.10
-
226
-
-
77954143718
-
Emodin enhances cisplatin-induced cytotoxicity via down- regulation of ERCC1 and inactivation of ERK1/2
-
10.1016/j.lungcan.2009.10.013, 19962780
-
Ko JC, Su YJ, Lin ST, Jhan JY, Ciou SC, Cheng CM, Chiu YF, Kuo YH, Tsai MS, Lin YW. Emodin enhances cisplatin-induced cytotoxicity via down- regulation of ERCC1 and inactivation of ERK1/2. Lung Cancer 2010, 69:155-164. 10.1016/j.lungcan.2009.10.013, 19962780.
-
(2010)
Lung Cancer
, vol.69
, pp. 155-164
-
-
Ko, J.C.1
Su, Y.J.2
Lin, S.T.3
Jhan, J.Y.4
Ciou, S.C.5
Cheng, C.M.6
Chiu, Y.F.7
Kuo, Y.H.8
Tsai, M.S.9
Lin, Y.W.10
-
227
-
-
33745938530
-
The angiosuppressive effects of 20(R)- ginsenoside Rg3
-
10.1016/j.bcp.2006.04.034, 16793023
-
Yue PY, Wong DY, Wu PK, Leung PY, Mak NK, Yeung HW, Liu L, Cai Z, Jiang ZH, Fan TP, Wong RN. The angiosuppressive effects of 20(R)- ginsenoside Rg3. Biochem Pharmacol 2006, 72:437-445. 10.1016/j.bcp.2006.04.034, 16793023.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 437-445
-
-
Yue, P.Y.1
Wong, D.Y.2
Wu, P.K.3
Leung, P.Y.4
Mak, N.K.5
Yeung, H.W.6
Liu, L.7
Cai, Z.8
Jiang, Z.H.9
Fan, T.P.10
Wong, R.N.11
-
228
-
-
68249155377
-
Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice
-
10.1186/1471-2407-9-250, 2721848, 19624862
-
Liu TG, Huang Y, Cui DD, Huang XB, Mao SH, Ji LL, Song HB, Yi C. Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice. BMC Cancer 2009, 9:250. 10.1186/1471-2407-9-250, 2721848, 19624862.
-
(2009)
BMC Cancer
, vol.9
, pp. 250
-
-
Liu, T.G.1
Huang, Y.2
Cui, D.D.3
Huang, X.B.4
Mao, S.H.5
Ji, L.L.6
Song, H.B.7
Yi, C.8
-
229
-
-
67649361895
-
Inhibition of NF-kappaB by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel
-
10.1007/s12272-009-1515-4, 19471891
-
Kim SM, Lee SY, Yuk DY, Moon DC, Choi SS, Kim Y, Han SB, Oh KW, Hong JT. Inhibition of NF-kappaB by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel. Arch Pharm Res 2009, 32:755-765. 10.1007/s12272-009-1515-4, 19471891.
-
(2009)
Arch Pharm Res
, vol.32
, pp. 755-765
-
-
Kim, S.M.1
Lee, S.Y.2
Yuk, D.Y.3
Moon, D.C.4
Choi, S.S.5
Kim, Y.6
Han, S.B.7
Oh, K.W.8
Hong, J.T.9
-
230
-
-
76549121864
-
Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB
-
10.1016/j.ejphar.2009.12.018, 20056115
-
Kim SM, Lee SY, Cho JS, Son SM, Choi SS, Yun YP, Yoo HS, Yoon do Y, Oh KW, Han SB, Hong JT. Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB. Eur J Pharmacol 2010, 631:1-9. 10.1016/j.ejphar.2009.12.018, 20056115.
-
(2010)
Eur J Pharmacol
, vol.631
, pp. 1-9
-
-
Kim, S.M.1
Lee, S.Y.2
Cho, J.S.3
Son, S.M.4
Choi, S.S.5
Yun, Y.P.6
Yoo, H.S.7
Yoon do, Y.8
Oh, K.W.9
Han, S.B.10
Hong, J.T.11
-
231
-
-
16544379730
-
Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells
-
10.1007/BF02980085, 15180309
-
Kim HS, Lee EH, Ko SR, Choi KJ, Park JH, Im DS. Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells. Arch Pharm Res 2004, 27:429-435. 10.1007/BF02980085, 15180309.
-
(2004)
Arch Pharm Res
, vol.27
, pp. 429-435
-
-
Kim, H.S.1
Lee, E.H.2
Ko, S.R.3
Choi, K.J.4
Park, J.H.5
Im, D.S.6
-
232
-
-
78651246162
-
Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling
-
He BC, Gao JL, Luo X, Luo J, Shen J, Wang L, Zhou Q, Wang YT, Luu HH, Haydon RC, Wang CZ, Du W, Yuan CS, He TC, Zhang BQ. Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling. Int J Oncol 2011, 38:437-445.
-
(2011)
Int J Oncol
, vol.38
, pp. 437-445
-
-
He, B.C.1
Gao, J.L.2
Luo, X.3
Luo, J.4
Shen, J.5
Wang, L.6
Zhou, Q.7
Wang, Y.T.8
Luu, H.H.9
Haydon, R.C.10
Wang, C.Z.11
Du, W.12
Yuan, C.S.13
He, T.C.14
Zhang, B.Q.15
-
233
-
-
45849092251
-
Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells
-
2677725, 18425323
-
Luo X, Wang CZ, Chen J, Song WX, Luo J, Tang N, He BC, Kang Q, Wang Y, Du W, He TC, Yuan CS. Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells. Int J Oncol 2008, 32:975-983. 2677725, 18425323.
-
(2008)
Int J Oncol
, vol.32
, pp. 975-983
-
-
Luo, X.1
Wang, C.Z.2
Chen, J.3
Song, W.X.4
Luo, J.5
Tang, N.6
He, B.C.7
Kang, Q.8
Wang, Y.9
Du, W.10
He, T.C.11
Yuan, C.S.12
-
234
-
-
67249166275
-
Proteomic analysis of the anti-cancer effect of 20S-ginsenoside Rg3 in human colon cancer cell lines
-
10.1271/bbb.80637, 19352032
-
Lee SY, Kim GT, Roh SH, Song JS, Kim HJ, Hong SS, Kwon SW, Park JH. Proteomic analysis of the anti-cancer effect of 20S-ginsenoside Rg3 in human colon cancer cell lines. Biosci Biotechnol Biochem 2009, 73:811-816. 10.1271/bbb.80637, 19352032.
-
(2009)
Biosci Biotechnol Biochem
, vol.73
, pp. 811-816
-
-
Lee, S.Y.1
Kim, G.T.2
Roh, S.H.3
Song, J.S.4
Kim, H.J.5
Hong, S.S.6
Kwon, S.W.7
Park, J.H.8
-
235
-
-
51349149844
-
Inhibitory effect of ginsenoside Rg3 on ovarian cancer metastasis
-
Xu TM, Cui MH, Xin Y, Gu LP, Jiang X, Su MM, Wang DD, Wang WJ. Inhibitory effect of ginsenoside Rg3 on ovarian cancer metastasis. Chin Med J (Engl) 2008, 121:1394-1397.
-
(2008)
Chin Med J (Engl)
, vol.121
, pp. 1394-1397
-
-
Xu, T.M.1
Cui, M.H.2
Xin, Y.3
Gu, L.P.4
Jiang, X.5
Su, M.M.6
Wang, D.D.7
Wang, W.J.8
-
236
-
-
33644618424
-
Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma
-
10.1016/j.bbrc.2006.02.044, 16499874
-
Zhang Q, Kang X, Zhao W. Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma. Biochem Biophys Res Commun 2006, 342:824-828. 10.1016/j.bbrc.2006.02.044, 16499874.
-
(2006)
Biochem Biophys Res Commun
, vol.342
, pp. 824-828
-
-
Zhang, Q.1
Kang, X.2
Zhao, W.3
|