Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation

Toxicology and Applied Pharmacology

Volumn 229, Issue 1, 2008, Pages 33-43

  Meeran, Syed M ^a   Katiyar, Suchitra ^a   Katiyar, Santosh K ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Berberine; Mitochondrial disruption; Reactive oxygen species; Xanthine oxidase

Indexed keywords

ACETYLCYSTEINE; ALLOPURINOL; BERBERINE; CASPASE 3; CASPASE 9; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 2; REACTIVE OXYGEN METABOLITE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; XANTHINE OXIDASE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; OXIDATIVE STRESS; PROSTATE CANCER; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BERBERINE; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; COLLAGEN TYPE XI; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES;

EID: 42749085774     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.12.027     Document Type: Article

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