Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through mitochondrial/caspases pathway

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 4, 2008, Pages 558-562

  Eom, Ki Seong ^a   Hong, Ji Myoung ^a   Youn, Myung Ja ^b   So, Hong Seob ^b   Park, Raekil ^b   Kim, Jong Moon ^a   Kim, Tae Young ^a  

^a Wonkwang University Hospital   (South Korea)

^b Wonkwang University   (South Korea)

Author keywords

Apoptosis; Berberine; G1 arrest; Glioblastoma; Mitochondrial; T98G cell

Indexed keywords

BERBERINE; CASPASE; CASPASE 3; CASPASE 9; CYCLIN D; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 9; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P27;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL NUCLEUS; CELL VIABILITY; CHINESE MEDICINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; GLIOBLASTOMA; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; STATISTICAL ANALYSIS; WESTERN BLOTTING;

APOPTOSIS; BERBERINE; BLOTTING, WESTERN; BRAIN NEOPLASMS; CASPASES; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; G1 PHASE; GLIOBLASTOMA; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; POLY(ADP-RIBOSE) POLYMERASES; SIGNAL TRANSDUCTION;

EID: 41849122326     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.558     Document Type: Article

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