The combination of berberine and irradiation enhances anti-cancer effects via activation of p38 MAPK pathway and ROS generation in human hepatoma cells

Journal of Cellular Biochemistry

Volumn 107, Issue 5, 2009, Pages 955-964

  Hur, Jung Mu ^a   Hyun, Mee Sun ^b   Lim, Sang Yong ^c   Lee, Woo Yiel ^d   Kim, Dongho ^c  

^a Chong Kun Dang Healthcare Corp Research Center   (South Korea)

^b Wonkwang University   (South Korea)

^c Korea Atomic Energy Research Institute   (South Korea)

^d Konyang University   (South Korea)

Author keywords

Apoptosis; Berberine; p38; Radiation; Radiotherapy; ROS

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; BERBERINE; CASPASE 3; ISOQUINOLINE ALKALOID; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; FLOW CYTOMETRY; GAMMA IRRADIATION; HEPATOMA CELL; HUMAN; HUMAN CELL; IONIZING RADIATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RADIOSENSITIZATION; STATISTICAL ANALYSIS; WESTERN BLOTTING;

ACETYLCYSTEINE; APOPTOSIS; BERBERINE; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME ACTIVATION; HUMANS; LIVER NEOPLASMS; MODELS, BIOLOGICAL; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION, IONIZING; REACTIVE OXYGEN SPECIES;

EID: 67749133572     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22198     Document Type: Article

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