Triptolide and TRAIL combination enhances apoptosis in cholangiocarcinoma

Journal of Surgical Research

Volumn 163, Issue 2, 2010, Pages 244-249

  Clawson, Kimberly A ^a   Borja Cacho, Daniel ^a   Antonoff, Mara B ^a   Saluja, Ashok K ^a   Vickers, Selwyn M ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

apoptosis; cholangiocarcinoma; PARP; TRAIL; triptolide; XIAP

Indexed keywords

ACTIN; CASPASE 3; CASPASE 7; CASPASE 9; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TRIPTOLIDE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS; DITERPENE; EPOXIDE; PHENANTHRENE DERIVATIVE; XIAP PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BILE DUCT CARCINOMA; CANCER COMBINATION CHEMOTHERAPY; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; BILE DUCT NEOPLASMS; CELL SURVIVAL; CHOLANGIOCARCINOMA; DRUG EFFECTS; INTRAHEPATIC BILE DUCT; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANNEXIN A5; APOPTOSIS; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CHOLANGIOCARCINOMA; DITERPENES; DRUG SYNERGISM; EPOXY COMPOUNDS; HUMANS; PHENANTHRENES; POLY(ADP-RIBOSE) POLYMERASES; TNF-RELATED APOPTOSIS-INDUCING LIGAND; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 77956901995     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2010.03.067     Document Type: Article

References (16)

1. M. Aljiffry, M.J. Walsh, and M. Molinari Advances in diagnosis, treatment and palliation of cholangiocarcinoma: 1990-2009 World J Gastroenterol 15 2009 34 Review
2. T. Patel Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States Hepatology 33 2001 6
3. P.A. Phillips, V. Dudeja, and J.A. McCarroll Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70 Cancer Res 67 2007 19
4. M.B. Antonoff, R. Chugh, and D. Borja-Cacho Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo Surgery 146 2009 2
5. D. Borja-Cacho, Y. Yokoyama, and R.K. Chugh TRAIL and triptolide: An effective combination that induces apoptosis in pancreatic cancer cells J Gastrointest Surg 2009 (in press)
6. S.R. Wiley, K. Schooley, and P.J. Smolak Identification and characterization of a new member of the TNF family that induces apoptosis Immunity 3 1995 6
7. A. Ashkenazi, R.C. Pai, and S. Fong Safety and antitumor activity of recombinant soluble Apo2 ligand J Clin Invest 104 1999 2
8. M.M. Keane, S.A. Ettenberg, and M.M. Nau Chemotherapy augments TRAIL-induced apoptosis in breast cell lines Cancer Res 59 1999 3
9. H. Walczak, R.E. Miller, and K. Ariail Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo Nat Med 5 1999 2
10. Y. Mizutani, O. Yoshida, and T. Miki Synergistic cytotoxicity and apoptosis by Apo-2 ligand and adriamycin against bladder cancer cells Clin Cancer Res 5 1999 9
11. A. Basu, V.P. Castle, and M. Bouziane Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: Synergistic action of estrogen metabolite and ligands of death receptor family Cancer Res 66 2006 8
12. S. Frese, F. Pirnia, and D. Miescher PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2 Oncogene 22 2003 35
13. B.Z. Carter, D.H. Mak, and W.D. Schober Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5 Blood 111 2008 7
14. T. Panichakul, P. Intachote, and A. Wongkajorsilp Triptolide sensitizes resistant cholangiocarcinoma cells to TRAIL-induced apoptosis Anticancer Res 26 2006 1A
15. E.A. Slee, C. Adrain, and S.J. Martin Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis J Biol Chem 276 2001 10
16. Q.L. Deveraux, R. Takahashi, and G.S. Salvesen X-linked IAP is a direct inhibitor of cell-death proteases Nature 388 1997 6639