Berberine, a natural product, combined with cisplatin enhanced apoptosis through a mitochondria/caspase-mediated pathway in HeLa cells

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 5, 2008, Pages 789-795

  Youn, Myung Ja ^a   So, Hong Seob ^a   Cho, Hea Joong ^a   Kim, Hyung Jin ^a   Kim, Yunha ^a   Lee, Jeong Han ^a   Sohn, Jung Sook ^a   Kim, Yong Kyu ^a   Chung, Sang Young ^b   Park, Raekil ^a  

^a Wonkwang University   (South Korea)

^b Chonnam National University Medical School   (South Korea)

Author keywords

Apoptosis; Berberine; Cisplatin; Combined treatment; Mitochondria caspase pathway

Indexed keywords

BERBERINE; CASPASE; CISPLATIN; CYTOCHROME C; LIPOCORTIN 5; PROPIDIUM IODIDE; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE;

ADD ON THERAPY; APOPTOSIS; ARTICLE; CELL LABELING; CONTROLLED STUDY; CYTOFLUOROMETRY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; FEMALE; HELA CELL; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BERBERINE; CASPASES; CISPLATIN; CYTOCHROMES C; DNA FRAGMENTATION; DRUG SYNERGISM; ENZYME ACTIVATION; HELA CELLS; HUMANS; INDICATORS AND REAGENTS; LIPID PEROXIDATION; MEMBRANE POTENTIALS; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES;

EID: 44349121204     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.789     Document Type: Article

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