Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron

Free Radical Biology and Medicine

Volumn 37, Issue 7, 2004, Pages 998-1009

  Efferth, Thomas ^a   Benakis, Achille ^b   Romero, Marta R ^c   Tomicic, Maja ^d   Rauh, Rolf ^d   Steinbach, Daniel ^e   Häfer, Ralf ^e   Stamminger, Thomas ^f   Oesch, Franz ^d   Kaina, Bernd ^d   Marschall, Manfred ^f  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c UNIVERSITY OF SALAMANCA   (Spain)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

^e FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^f UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Artemisinin; Artesunate; Free radicals; Iron(II) glycine sulfate; Transferrin

Indexed keywords

ACONITATE HYDRATASE; ARTEMISININ DERIVATIVE; ARTESUNATE; CERULOPLASMIN; FERROSANOL; FERROUS ION; IRON COMPLEX; IRON GLYCINE SULFATE; MESSENGER RNA; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY RVS 10; PROTEIN P53; TRANSFERRIN; TRANSFERRIN RECEPTOR; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ASTROCYTOMA CELL; BLOOD CELL; CANCER CELL; CELL CYCLE; CELL LINE; CELL POPULATION; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DRUG METABOLISM; GENE; GENE EXPRESSION; GENE MUTATION; GROWTH INHIBITION; HEALTH CARE ORGANIZATION; HUMAN; HUMAN CELL; IC 50; IRON RESPONSIVE ELEMENT; IRON TRANSPORT; LEUKEMIA CELL; LYMPHOBLASTOID CELL; MICROENCAPSULATION; MONONUCLEAR CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; TUMOR CELL; WILD TYPE;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; ARTEMISININS; CELL LINE, TUMOR; CELL PROLIFERATION; FERROUS COMPOUNDS; GENE EXPRESSION REGULATION; HUMANS; INHIBITORY CONCENTRATION 50; IRON; NEOPLASMS; RECEPTORS, TRANSFERRIN; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

ARTESUNATE;

EID: 4444383530     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.06.023     Document Type: Article

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