-
1
-
-
33846457870
-
Cancer statistics, 2007
-
Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2007. CA Cancer J Clin. 2007 57 : 43 66.
-
(2007)
CA Cancer J Clin.
, vol.57
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
3
-
-
17344378595
-
Gemcitabine combination chemotherapy of ovarian cancer
-
Mutch DG. Gemcitabine combination chemotherapy of ovarian cancer. Gynecol Oncol. 2003 90 : S16 20.
-
(2003)
Gynecol Oncol.
, vol.90
, pp. 16-20
-
-
Mutch, D.G.1
-
4
-
-
11244304289
-
Ovarian cancer: Review of the National Institute for Clinical Excellence (NICE) guidance recommendations
-
Johnston SR. Ovarian cancer: review of the National Institute for Clinical Excellence (NICE) guidance recommendations. Cancer Invest. 2004 22 : 730 42.
-
(2004)
Cancer Invest.
, vol.22
, pp. 730-42
-
-
Johnston, S.R.1
-
5
-
-
0023681189
-
Mechanism of cis-diamminedichloroplatinum(II)-induced cytotoxicity: Role of G2 arrest and DNA double-strand breaks
-
Sorenson CM, Eastman A. Mechanism of cis-diamminedichloroplatinum(II)- induced cytotoxicity: role of G2 arrest and DNA double-strand breaks. Cancer Res. 1988 48 : 4484 8.
-
(1988)
Cancer Res.
, vol.48
, pp. 4484-8
-
-
Sorenson, C.M.1
Eastman, A.2
-
6
-
-
38049169298
-
On the hydrolysis mechanism of the second-generation anticancer drug carboplatin
-
Pavelka M, Lucas MF, Russo N. On the hydrolysis mechanism of the second-generation anticancer drug carboplatin. Chemistry. 2007 13 : 10108 16.
-
(2007)
Chemistry.
, vol.13
, pp. 10108-16
-
-
Pavelka, M.1
Lucas, M.F.2
Russo, N.3
-
7
-
-
0043240182
-
Ovarian cancer: Strategies for overcoming resistance to chemotherapy
-
Agarwal R, Kaye SB. Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer. 2003 3 : 502 16.
-
(2003)
Nat Rev Cancer.
, vol.3
, pp. 502-16
-
-
Agarwal, R.1
Kaye, S.B.2
-
8
-
-
0021948029
-
Qinghaosu (artemisinin): An antimalarial drug from China
-
Klayman DL. Qinghaosu (artemisinin): an antimalarial drug from China. Science. 1985 228 : 1049 55.
-
(1985)
Science.
, vol.228
, pp. 1049-55
-
-
Klayman, D.L.1
-
9
-
-
0035194318
-
Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells
-
Singh NP, Lai H. Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells. Life Sci. 2001 70 : 49 56.
-
(2001)
Life Sci.
, vol.70
, pp. 49-56
-
-
Singh, N.P.1
Lai, H.2
-
10
-
-
0037021402
-
Antimalarial chemotherapeutic peroxides: Artemisinin, yingzhaosu A and related compounds
-
Borstnik K, Paik IH, Shapiro TA, Posner GH. Antimalarial chemotherapeutic peroxides: artemisinin, yingzhaosu A and related compounds. Int J Parasitol. 2002 32 : 1661 7.
-
(2002)
Int J Parasitol.
, vol.32
, pp. 1661-7
-
-
Borstnik, K.1
Paik, I.H.2
Shapiro, T.A.3
Posner, G.H.4
-
11
-
-
0022383509
-
Transferrin receptor: Its biological significance
-
May WS Jr., Cuatrecasas P. Transferrin receptor: its biological significance. J Membr Biol. 1985 88 : 205 15.
-
(1985)
J Membr Biol.
, vol.88
, pp. 205-15
-
-
May, Jr.W.S.1
Cuatrecasas, P.2
-
12
-
-
0028865074
-
Oral administration of dihydroartemisinin and ferrous sulfate retarded implanted fibrosarcoma growth in the rat
-
Moore JC, Lai H, Li JR, et al. Oral administration of dihydroartemisinin and ferrous sulfate retarded implanted fibrosarcoma growth in the rat. Cancer Lett. 1995 98 : 83 7.
-
(1995)
Cancer Lett.
, vol.98
, pp. 83-7
-
-
Moore, J.C.1
Lai, H.2
Li, J.R.3
-
13
-
-
0029037444
-
Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin
-
Lai H, Singh NP. Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin. Cancer Lett. 1995 91 : 41 6.
-
(1995)
Cancer Lett.
, vol.91
, pp. 41-6
-
-
Lai, H.1
Singh, N.P.2
-
14
-
-
0031726077
-
Artemisinin-derived sesquiter pene lactones as potential antitumour compounds: Cytotoxic action against bone marrow and tumour cells
-
Beekman AC, Wierenga PK, Woerdenbag HJ, et al. Artemisinin-derived sesquiter pene lactones as potential antitumour compounds: cytotoxic action against bone marrow and tumour cells. Planta Med. 1998 64 : 615 9.
-
(1998)
Planta Med.
, vol.64
, pp. 615-9
-
-
Beekman, A.C.1
Wierenga, P.K.2
Woerdenbag, H.J.3
-
15
-
-
0032725336
-
Antimalarial, antiproliferative, and antitumor activities of artemisinin-derived, chemically robust, trioxane dimers
-
Posner GH, Ploypradith P, Parker MH, et al. Antimalarial, antiproliferative, and antitumor activities of artemisinin-derived, chemically robust, trioxane dimers. J Med Chem. 1999 42 : 4275 80.
-
(1999)
J Med Chem.
, vol.42
, pp. 4275-80
-
-
Posner, G.H.1
Ploypradith, P.2
Parker, M.H.3
-
16
-
-
0035315838
-
The anti-malarial artesunate is also active against cancer
-
Efferth T, Dunstan H, Sauerbrey A, et al. The anti-malarial artesunate is also active against cancer. Int J Oncol. 2001 18 : 767 73.
-
(2001)
Int J Oncol.
, vol.18
, pp. 767-73
-
-
Efferth, T.1
Dunstan, H.2
Sauerbrey, A.3
-
17
-
-
0038689359
-
Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro
-
Chen HH, Zhou HJ, Fang X. Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro. Pharmacol Res. 2003 48 : 231 6.
-
(2003)
Pharmacol Res.
, vol.48
, pp. 231-6
-
-
Chen, H.H.1
Zhou, H.J.2
Fang, X.3
-
18
-
-
11844269839
-
Effects of artemisinin-tagged holotransferrin on cancer cells
-
Lai H, Sasaki T, Singh NP, Messay A. Effects of artemisinin-tagged holotransferrin on cancer cells. Life Sci. 2005 76 : 1267 79.
-
(2005)
Life Sci.
, vol.76
, pp. 1267-79
-
-
Lai, H.1
Sasaki, T.2
Singh, N.P.3
Messay, A.4
-
19
-
-
28844439369
-
Oral artemisinin prevents and delays the development of 7,12-dimethylbenz[a]anthracene (DMBA) induced breast cancer in the rat
-
Lai H, Singh NP. Oral artemisinin prevents and delays the development of 7,12-dimethylbenz[a]anthracene (DMBA) induced breast cancer in the rat. Cancer Lett. 2006 231 : 43 8.
-
(2006)
Cancer Lett.
, vol.231
, pp. 43-8
-
-
Lai, H.1
Singh, N.P.2
-
20
-
-
4444261942
-
Artemisinin induces apoptosis in human cancer cells
-
Singh NP, Lai HC. Artemisinin induces apoptosis in human cancer cells. Anticancer Res. 2004 24 : 2277 80.
-
(2004)
Anticancer Res.
, vol.24
, pp. 2277-80
-
-
Singh, N.P.1
Lai, H.C.2
-
21
-
-
28244475056
-
Dihydroartemisinin is cytotoxic to papillomavirus-expressing epithelial cells in vitro and in vivo
-
Disbrow GL, Baege AC, Kierpiec KA, et al. Dihydroartemisinin is cytotoxic to papillomavirus-expressing epithelial cells in vitro and in vivo. Cancer Res. 2005 65 : 10854 61.
-
(2005)
Cancer Res.
, vol.65
, pp. 10854-61
-
-
Disbrow, G.L.1
Baege, A.C.2
Kierpiec, K.A.3
-
22
-
-
28844487481
-
Dihydroartemisinin downregulates vascular endothelial growth factor expression and induces apoptosis in chronic myeloid leukemia K562 cells
-
Lee J, Zhou HJ, Wu XH. Dihydroartemisinin downregulates vascular endothelial growth factor expression and induces apoptosis in chronic myeloid leukemia K562 cells. Cancer Chemother Pharmacol. 2006 57 : 213 20.
-
(2006)
Cancer Chemother Pharmacol.
, vol.57
, pp. 213-20
-
-
Lee, J.1
Zhou, H.J.2
Wu, X.H.3
-
23
-
-
8844258698
-
Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate
-
Dell'Eva R, Pfeffer U, Vene R, et al. Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate. Biochem Pharmacol. 2004 68 : 2359 66.
-
(2004)
Biochem Pharmacol.
, vol.68
, pp. 2359-66
-
-
Dell'Eva, R.1
Pfeffer, U.2
Vene, R.3
-
24
-
-
0037103574
-
MRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether
-
Efferth T, Olbrich A, Bauer R. mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether. Biochem Pharmacol. 2002 64 : 617 23.
-
(2002)
Biochem Pharmacol.
, vol.64
, pp. 617-23
-
-
Efferth, T.1
Olbrich, A.2
Bauer, R.3
-
25
-
-
0042844638
-
Molecular modes of action of artesunate in tumor cell lines
-
Efferth T, Sauerbrey A, Olbrich A, et al. Molecular modes of action of artesunate in tumor cell lines. Mol Pharmacol. 2003 64 : 382 94.
-
(2003)
Mol Pharmacol.
, vol.64
, pp. 382-94
-
-
Efferth, T.1
Sauerbrey, A.2
Olbrich, A.3
-
26
-
-
0141537877
-
Artemisinin inhibits inducible nitric oxide synthase and nuclear factor NF-kB activation
-
Aldieri E, Atragene D, Bergandi L, et al. Artemisinin inhibits inducible nitric oxide synthase and nuclear factor NF-kB activation. FEBS Lett. 2003 552 : 141 4.
-
(2003)
FEBS Lett.
, vol.552
, pp. 141-4
-
-
Aldieri, E.1
Atragene, D.2
Bergandi, L.3
-
27
-
-
33646024956
-
Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells
-
Efferth T. Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells. Curr Drug Targets. 2006 7 : 407 21.
-
(2006)
Curr Drug Targets.
, vol.7
, pp. 407-21
-
-
Efferth, T.1
-
28
-
-
33748157014
-
Dihydroartemisinin inhibits angiogenesis induced by multiple myeloma RPMI8226 cells under hypoxic conditions via downregulation of vascular endothelial growth factor expression and suppression of vascular endothelial growth factor secretion
-
Wu XH, Zhou HJ, Lee J. Dihydroartemisinin inhibits angiogenesis induced by multiple myeloma RPMI8226 cells under hypoxic conditions via downregulation of vascular endothelial growth factor expression and suppression of vascular endothelial growth factor secretion. Anticancer Drugs. 2006 17 : 839 48.
-
(2006)
Anticancer Drugs.
, vol.17
, pp. 839-48
-
-
Wu, X.H.1
Zhou, H.J.2
Lee, J.3
-
29
-
-
0035825365
-
Novel antitumor artemisinin derivatives targeting G1 phase of the cell cycle
-
Li Y, Shan F, Wu JM, et al. Novel antitumor artemisinin derivatives targeting G1 phase of the cell cycle. Bioorg Med Chem Lett. 2001 11 : 5 8.
-
(2001)
Bioorg Med Chem Lett.
, vol.11
, pp. 5-8
-
-
Li, Y.1
Shan, F.2
Wu, J.M.3
-
31
-
-
0035329255
-
Synthesis and cytotoxicity of artemisinin derivatives containing cyanoarylmethyl group
-
Wu JM, Shan F, Wu GS, et al. synthesis and cytotoxicity of artemisinin derivatives containing cyanoarylmethyl group. Eur J Med Chem. 2001 36 : 469 79.
-
(2001)
Eur J Med Chem.
, vol.36
, pp. 469-79
-
-
Wu, J.M.1
Shan, F.2
Wu, G.S.3
-
32
-
-
1642619557
-
Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1
-
Chen HH, Zhou HJ, Wu GD, Lou XE. Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1. Pharmacology. 2004 71 : 1 9.
-
(2004)
Pharmacology.
, vol.71
, pp. 1-9
-
-
Chen, H.H.1
Zhou, H.J.2
Wu, G.D.3
Lou, X.E.4
-
34
-
-
31444452870
-
Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane
-
Jung M, Tak J, Chung WY, Park KK. Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane. Bioorg Med Chem Lett. 2006 16 : 1227 30.
-
(2006)
Bioorg Med Chem Lett.
, vol.16
, pp. 1227-30
-
-
Jung, M.1
Tak, J.2
Chung, W.Y.3
Park, K.K.4
-
35
-
-
0035186743
-
Antisense anti-MDM2 oligonucleotides as a novel therapeutic approach to human breast cancer: In vitro and in vivo activities and mechanisms
-
Wang H, Nan L, Yu D, et al. Antisense anti-MDM2 oligonucleotides as a novel therapeutic approach to human breast cancer: in vitro and in vivo activities and mechanisms. Clin Cancer Res. 2001 7 : 3613 24.
-
(2001)
Clin Cancer Res.
, vol.7
, pp. 3613-24
-
-
Wang, H.1
Nan, L.2
Yu, D.3
-
36
-
-
33748457159
-
Immunomodulatory oligonucleotides as novel therapy for breast cancer: Pharma-cokinetics, in vitro and in vivo anti-cancer activity and potentiation of antibody therapy
-
Wang H, Rayburn E, Wang W, et al. Immunomodulatory oligonucleotides as novel therapy for breast cancer: pharma-cokinetics, in vitro and in vivo anti-cancer activity and potentiation of antibody therapy. Mol Cancer Ther. 2006 5 : 2106 14.
-
(2006)
Mol Cancer Ther.
, vol.5
, pp. 2106-14
-
-
Wang, H.1
Rayburn, E.2
Wang, W.3
-
37
-
-
0141482040
-
Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy
-
Zhang Z, Li M, Wang H, et al. Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy. Proc Natl Acad Sci USA. 2003 100 : 11636 41.
-
(2003)
Proc Natl Acad Sci USA.
, vol.100
, pp. 11636-41
-
-
Zhang, Z.1
Li, M.2
Wang, H.3
-
38
-
-
1942437554
-
MDM2 is a negative regulator of p21 WAF1/CIP1, independent of p53
-
Zhang Z, Wang H, Li M, et al. MDM2 is a negative regulator of p21 WAF1/CIP1, independent of p53. J Biol Chem. 2004 279 : 16000 6.
-
(2004)
J Biol Chem.
, vol.279
, pp. 16000-6
-
-
Zhang, Z.1
Wang, H.2
Li, M.3
-
39
-
-
27944478688
-
Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway
-
Zhang Z, Wang H, Li M, et al. Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway. Oncogene. 2005 24 : 7238 47.
-
(2005)
Oncogene.
, vol.24
, pp. 7238-47
-
-
Zhang, Z.1
Wang, H.2
Li, M.3
-
40
-
-
0033598705
-
Anti-tumor activity and pharmacokinetics of a mixed-backbone antisense oligonucleotide targeted to RI. subunit of protein kinase A after oral administration
-
Wang H, Cai Q, Zeng X, et al. Anti-tumor activity and pharmacokinetics of a mixed-backbone antisense oligonucleotide targeted to RI. subunit of protein kinase A after oral administration. Proc Natl Acad Sci USA. 1999 96 : 13989 94.
-
(1999)
Proc Natl Acad Sci USA.
, vol.96
, pp. 13989-94
-
-
Wang, H.1
Cai, Q.2
Zeng, X.3
-
41
-
-
1842428890
-
Pretreatment with dexamethasone increases anti-tumor activity of carboplatin and gemcitabine in mice bearing human cancer xenografts: In vivo activity, pharmacokinetics and clinical implications for cancer chemotherapy
-
Wang H, Li M, Rinehart JJ, Zhang R. Pretreatment with dexamethasone increases anti-tumor activity of carboplatin and gemcitabine in mice bearing human cancer xenografts: in vivo activity, pharmacokinetics and clinical implications for cancer chemotherapy. Clin Cancer Res. 2004 10 : 1633 44.
-
(2004)
Clin Cancer Res.
, vol.10
, pp. 1633-44
-
-
Wang, H.1
Li, M.2
Rinehart, J.J.3
Zhang, R.4
-
42
-
-
0037188425
-
Transferrin overcomes drug resistance to artemisinin in human small-cell lung carcinoma cells
-
Sadava D, Phillips T, Lin C, Kane SE. Transferrin overcomes drug resistance to artemisinin in human small-cell lung carcinoma cells. Cancer Lett. 2002 179 : 151 6.
-
(2002)
Cancer Lett.
, vol.179
, pp. 151-6
-
-
Sadava, D.1
Phillips, T.2
Lin, C.3
Kane, S.E.4
-
43
-
-
33646984927
-
Dihydroartemisinin enhances radiosensitivity of human glioma cells in vitro
-
Kim SJ, Kim MS, Lee JW, et al. Dihydroartemisinin enhances radiosensitivity of human glioma cells in vitro. J Cancer Res Clin Oncol. 2006 132 : 129 35.
-
(2006)
J Cancer Res Clin Oncol.
, vol.132
, pp. 129-35
-
-
Kim, S.J.1
Kim, M.S.2
Lee, J.W.3
-
44
-
-
34347389476
-
Dihydroartemisinin is an inhibitor of ovarian cancer cell growth
-
Jiao Y, Ge CM, Meng QH, et al. Dihydroartemisinin is an inhibitor of ovarian cancer cell growth. Acta Pharmacol Sin. 2007 28 : 1045 56.
-
(2007)
Acta Pharmacol Sin.
, vol.28
, pp. 1045-56
-
-
Jiao, Y.1
Ge, C.M.2
Meng, Q.H.3
-
45
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO. The biochemistry of apoptosis. Nature. 2000 407 : 770 6.
-
(2000)
Nature.
, vol.407
, pp. 770-6
-
-
Hengartner, M.O.1
-
46
-
-
0346873049
-
Anticancer therapy targeting the apoptotic pathway
-
Hu W, Kavanagh JJ. Anticancer therapy targeting the apoptotic pathway. Lancet Oncol. 2003 4 : 721 9.
-
(2003)
Lancet Oncol.
, vol.4
, pp. 721-9
-
-
Hu, W.1
Kavanagh, J.J.2
-
48
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 1999 13 : 1899 911.
-
(1999)
Genes Dev.
, vol.13
, pp. 1899-911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
|