Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors

Journal of Surgical Research

Volumn 168, Issue 2, 2011, Pages 197-205

  Johnson, Sara M ^a   Wang, Xiaofu ^b,c   Evers, B Mark ^b,c  

^a University of Texas Medical Branch School of Medicine   (United States)

^b Department of Surgery ^*  (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

cell cycle; chemokine; colorectal cancer; growth factor receptors; herbal extract; triptolide

Indexed keywords

ANTINEOPLASTIC AGENT; CHEMOKINE RECEPTOR CXCR4; COMPLEMENTARY DNA; CYCLIN A; CYCLIN B; CYCLIN C; CYCLIN D; CYCLOOXYGENASE 2; GLYCOPROTEIN GP 130; INTERLEUKIN 6 RECEPTOR ALPHA; MESSENGER RNA; MYC PROTEIN; THROMBIN RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRIPTOLIDE; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; VASCULOTROPIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER INVASION; CELL ASSAY; CELL CYCLE ARREST; CELL PROLIFERATION; CELL STRAIN HCT116; CELL STRAIN HT29; COLORECTAL CANCER; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; HUMAN; HUMAN CELL; MIGRATION INHIBITION; NORTHERN BLOTTING; PRIORITY JOURNAL; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, ALKYLATING; CELL MOVEMENT; CELL PROLIFERATION; CYCLINS; CYCLOOXYGENASE 2; DITERPENES; DRUG EVALUATION, PRECLINICAL; EPIDERMAL GROWTH FACTOR; EPOXY COMPOUNDS; HCT116 CELLS; HT29 CELLS; HUMANS; NEUROTENSIN; PHENANTHRENES; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, CXCR4; RECEPTORS, CYTOKINE; RECEPTORS, THROMBIN; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRIPTERYGIUM; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79955831016     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2009.07.002     Document Type: Article

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