Pharmacology and phytochemistry of pakistani herbs and herbal drugs used for treatement of diabetes

International Journal of Pharmacology

Volumn 7, Issue 4, 2011, Pages 419-439

  Karim, Asia ^a   Nouman, Muhammad ^a   Munir, Saba ^a   Sattar, Saba ^b  

^a Asian Network for Scientific Information   (Pakistan)

^b Irrigation and Power Department   (Pakistan)

Author keywords

Antioxidant mechanism; Diabetic complications; Herbal remedies; Oxidative stree; Toxicity

Indexed keywords

ALOE VERA EXTRACT; ALPHA GLUCOSIDASE INHIBITOR; ARTEMISIA HERBA ALBA EXTRACT; CATHARANTHUS ROSEUS EXTRACT; CICHORIUM INTYBU EXTRACT; CORIANDRUM SATIVUM EXTRACT; CUCURBITA MAXIMA EXTRACT; ELEPHANTOPUS SCABER EXTRACT; EQUISETUM ARVENSE EXTRACT; GARLIC EXTRACT; GINGER EXTRACT; GLIBENCLAMIDE; GLITAZONE DERIVATIVE; INSULIN; METFORMIN; MOMORDICA CHARANTIA EXTRACT; MURRAYA KOENIGII EXTRACT; OCIMUM SANCTUM EXTRACT; ONION EXTRACT; PHYLLANTHUS AMARUS EXTRACT; PLANT EXTRACT; SEMECARPUS ANACARDIUM EXTRACT; SILYBUM MARIANUM EXTRACT; SULFONYLUREA DERIVATIVE; TRIGONELLA FOENUM GRAECUM EXTRACT; UNCLASSIFIED DRUG;

AGE DISTRIBUTION; ANTIDIABETIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTEMISIA HERBA ALBA; ARTICLE; CARDIOVASCULAR DISEASE; CHICORY; COLOCYNTH; DRUG ACTIVITY; DRUG EFFICACY; DRUG SAFETY; ELEPHANTOPUS SCABER; EQUISETUM; EQUISETUM ARVENSE; GLYCEMIC CONTROL; HUMAN; HYPOGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; LACTIC ACIDOSIS; LIVER PROTECTION; MALABSORPTION; MEDICINAL PLANT; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PHYTOCHEMISTRY; PLANT LEAF; RENAL PROTECTION; SEX DIFFERENCE; SIDE EFFECT; SQUASH; SYSTEMATIC REVIEW; URBAN RURAL DIFFERENCE; WEIGHT GAIN;

EID: 79959437718     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2011.419.439     Document Type: Article

References (307)

1. Abbas, R.J., 2010. Effect of using fenugreek, parsley and sweet basil seeds as feed additives on the performance of broiler chickens. Int. J. Poult. Sci., 9: 278-282.
2. Abdel Gadir, E.H., W.S. Abdel Gadir and S.E.I. Adam, Response of wistar rats to low levels of dietary Allium cepa, Allium sativum and sodium selenite. J. Pharmacol. Toxicol, 1: 284-288.
3. Abdel-Gadir, E.H., W.S. Abdel-Gadir and S.E.I. Adam, Toxicologic interaction of potassium bromate and Allium cepa, Allium sativum or sodium selenite in wistar rats. J. Pharmacol. Toxicol., 2: 496-501.
4. Abdel-Hassan, LA., LA. Abdel-Barry and S.T. Mohammeda, 2000. The hypoglycaemic and antihyperglycaemic effect of Citrullus colocynthis fruit aqueous extract in normal and alloxan diabetic rabbits. J. Ethnopharmacol., 71: 325-330.
5. Abe, K., N. Okada, H. Tanabe, R. Fukutomi, K. Yasui, M. Isemura and N. Kinae, 2009. Effects of chronic ingestion of catechin-rich green tea on hepatic gene expression of gluconeogenic enzymes in rats. Biomed. Res., 30: 25-29.
6. Abeer Waggas, M., 2009. Neuroprotective evaluation of extract of ginger (Zingiber officinale) root in monosodium glutamate-induced toxicity in different brain areas of male albino rats. Pak. J. Biol. Sci., 12: 201-212.
7. Abera, A., F. Lemessa and D. Muleta, 2011. The antifungal activity of some medicinal plants against coffee berry disease caused by Colletotrichum kahawae. Int. J. Agric. Res., 6: 268-279.
8. Adanlawo, I.G. and F.A.S. Dairo, 2007. Nutrient and anti-nutrient constituents of ginger (Zingiber officinale, Roscoe) and the influence of its ethanolic extract on some serum enzymes in albino rats. Int. J. Biol. Chem., 1: 38-46.
9. Adebolu, T.T., P.T. Adeboye and N.B. Adegbola, 2007. Evaluation of a traditional decoction made from Psidium guajava and Zingiber officinale for anti bacterial activity. Res. J. Microbiol., 2: 954-959.
10. Adedapo, A.A., M.O. Abatan, S.O. Idowu and O.O. Olorunsogo, 2005. Toxic effects of chromatographic fractions of Phyllanthus amarus on the serum biochemistry of rats. Phytother. Res., 19: 812-815.
11. Adeneye, A.A., O.O. Amole and A.K. Adeneye, 2006. Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extracts of Phyllanthus amarus in mice. Fitoterapia, 77: 511-514.
12. Ahmed, A.U., A.H. Ferdous, S.K. Saha, S. Nahar, M.A. Awal and F. Parvin, 2007. Hypoglycemic effect of Catharanthus roseus in normal and streptozotocin-induced diabetic rats. Mymensingh Med. J., 16: 143-148.
13. Ahmad, M., R. Qureshi, M. Arshad, M.A. Khan and M. Zafar, 2009. Traditional herbal remedies used for the treatment of diabetes from district Attock (Pakistan). Pak. J. Bot, 41: 2777-2782.
14. Akhani, S.P., S.L. Vishwakarma and R.K. Goyal, 2004. Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. J. Pharm. Pharmacol, 56: 101-105.
15. Akram, M., M.I. Shah, K. Usmanghan, E. Mohiuddin and A. Sami et al., 2011. Zingiber officinale roscoe (A medicinal plant). Pak. J. Nutr., 10: 399-400.
16. Al-Amin, Z.M., M. Thomson, K.K. Al-Qattan, R. Peltonen-Shalaby and M. Ali, 2006. Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats. Br. J. Nutr., 96: 660-666.
17. Al-Ghaithi, F., M.R. El-Ridi, E. Adeghate and M.H. Amin, 2004. Biochemical effects of Citrullus colocynthis in normal and diabetic rats. Mol. Cell Biochem., 261: 143-149.
18. Al-Mustafa, A.H. and O.Y. Al-Thumbat, 2008. Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes. Pak. J. Biol. Sci., 11: 351-358.
19. Al-Shamaony, L., S.M. AI-Khazraji and H.A. Twayi, 1994. Hypoglycemic effect of Artemisia herba alba 2. Effect of a valuable extract on some blood parameters in diabetic animals. J. Ethnopharmacol., 43: 167-171.
20. Al-Sobayil, F.A., 2008. Accelerative effect of fenugreek seeds on the healing of mandibular fracture in male dromedary camels and monitoring of the healing by bone biomarkers. Res. J. Medicinal Plant, 2: 92-99.
21. Alberti, K.G. and P.Z. Zimmet, 1998. Definition, diagnosis and classification of diabetes mellitus and its complications: Part 1. Diagnosis and classification of diabetes mellitus, provisional report of a WHO consultation. Diabetic Med., 15: 539-553.
22. Ali, H., P.J. Houghton and A. Soumyanath, 2006. A-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllantus amarus. J. Ethnopharmacol., 107: 449-455.
23. Almasad, M.M., W.S. Qazan and H. Daradka, 2007. Reproductive toxic effects of Artemisia herba alba ingestion in female spague-dawley rats. Pak. J. Biol. Sci., 10: 3158-3161.
24. American Diabetes Association, 2010. Diagnosis and classification of diabetes mellitus. Diabetes Care, 33: S62-S69.
25. Andrade-Cetto, A. and H. Wiesdenfeld, 2001. Hypoglycemic effect of Cecropia obtusifolia on streptozotocin diabetic rats. J. Ethnopharmacol., 78: 145-149.
26. Annamalai, A. and P.T.V. Lakshmi, 2009. HPTLC and HPLC analysis of bioactive phyllanthin from different organs of Phyllanthus amarus. Asian J. Biotechnol., 1: 154-162.
27. Ara, N, M. Rashid and M.S. Amran, 2008. Comparison of hypotensive and hypolipidemic effects of Catharanthus roseus leaves extract with nifedipine on adrenaline induced hypertensive rats. J. Boil. Sci., 8: 1082-1086.
28. Arul, B., R. Kothai and A. J. Christina, 2004. Hypoglycemic and antihyperglycemic effect of Semecarpus Anacardium Linn in normal and streptozotocin-induced diabetic rats. Methods Find Exp. Clin. Pharmacol, 26: 759-762.
29. Arulselvan, P., G.P. Senthilkumar, S.D. Kumar and S. Subramanian, 2006. Anti-diabetic effect of Murraya koenigii leaves on streptozotocin induced diabetic rats. Pharmazie, 61: 874-877.
30. Arulselvan, P. and S.P. Subramanian, 2007. Beneficial effects of Murraya koenigii leaves on antioxidant defense system and ultra structural changes of pancreatic [3-cells in experimental diabetes in rats. Chem. Biol Interact., 165: 155-164.
31. Arulselvan, P. and S. Subramanian, 2008. Ultrastructural and biochemical abnormalities in the liver of streptozotocin-diabetic rats: Protective effects of murraya koenigii. J. Pharmacol. Toxicol, 3: 190-202.
32. Aruna, R.V., B. Ramesh and V.N. Kartha, 1999. Effect of betacarotene on protein glycosylation in alloxan induced diabetic rats. IndianJ. Exp. Biol., 37: 399-401.
33. Aseervatham, J., S. Palanivelu and S. Panchanadham, 2011. Semecarpus anacardium (Bhallataka) alters the glucose metabolism and energy production in diabetic rats. Evid. Based Complement. Alternat. Med, 10.1155/2011/142978
34. Asha, B., K.H. Krishnamurthy and S. Devaru, 2011. Evaluation of anti hyperglycaemic activity of Zingiber officinale (Ginger) in albino rats. J. Chem. Pharm. Res., 3: 452-456.
35. Asiamah, D., M. Verghese, J. Boateng, B. Kanda, L. Shackelford and L.T. Walker, 2011. Chemopreventive potential of bitter melon (Momordica charantia) against precancerous lesions in the colon of fisher 344 male rats. Int. J. Cancer Res., 7: 36-46.
36. Ataman, J.E., D.B. Grillo, E.K.I. Omongbai, M. Idu, F. Amaechina, V. Okonji and B.A. Ayinde, 2006. Effect of methanolic extract of Momordica charantia L. leaves on alloxan treated wistar rats. J. Medical Sci., 6: 828-832.
37. Ataman, J.E. and M. Idu, 2007. Histopathologic effects of methanolic extract of Momordica charantia L. leaves on the liver of wistar rats. Trends Med. Res., 2: 176-184.
38. Augusti, K.T., 1996. Therapeutic values of onion (Allium cepa L.) and garlic (Allium sativum L.). Indian J. Exp. Biol, 34: 634-640.
39. Augusti, K.T. and C.G. Sheela, 1996. Antiperoxide effect of S-allyl cysteine sulfoxide, an insulin secretagogue, in diabetic rats. Cellular Mol. Life Sci., 52: 115-119.
40. Avci, A., M. Kacmaz, M. Kavutcu, E. Gocmen and I. Durak, 2005. Effects of an antioxidant extract on adenosine deaminase activities in cancerous human liver tissues. Int. J. Cancer Res., 1: 53-56.
41. Bahrain, D., E.D. Mansour, T. Alireza and N. Afshin, 2005. Effects of germinated seeds of Trigonella foenum graecum (Fenugreek) and cholestyramine on blood lipids profile and aortic fatty streak in rabbit. Pak. J. Biol. Sci., 8: 1529-1532.
42. Bailey, C.J. and R.C. Turner, 1996. Metformin. N. Engl. J. Med, 334: 574-579.
43. Bankole, H.A., O.A. Magbagbeola, O.B. Adu, A.A. Fatai and B.A. James, 2011. Biochemical Effect of Ethanolic Extract of Phyllanthus amarus (Euphorbiaceae) on Plasma Nitric Oxide and Penile Cyclic Guanosine Monophosphate (cGMP) in Mature Male Guinea Pigs Asian J. Biochem., 6: 291-299.
44. Banu, L.A. and M.A. Bari, 2007. Protocol establishment for multiplication and regeneration of Ocimum sanctum Linn, an important medicinal plant with high religious value in Bangladesh. J. Plant Sci., 2: 530-537.
45. Basaran, A.A., K.F. Ciftci and S. Kusmenoglu, 1998. Characteristics of Turkish Cucurbita maxima duch seed oil. Acta Pharm. Sci., 40: 17-20.
46. Bavarva, J.H. and A.V.R.L. Narasimhacharya, 2007. Comparative antidiabetic, hypolipidemic and antioxidant properties of Phyllanthus niruri. in normal and diabetic rats. Pharm. Biol., 45: 569-574.
47. Bharadwaj, A. and S. Sharma, 2007. Effect of some plant extracts on the hatch of Meloidogyne incognita eggs. Int. J. Bot, 3: 312-316.
48. Bonjar, G.H.S., 2004. Screening for antibacterial properties of some iranian plants against two strains of Escherichia coli. Asian J. Plant Sci., 3: 310-314.
49. Boulenouar, N, A. Marouf and A. Chenti, 2009. Effect of some poisonous plants extracts on Fusarium oxysporum f. sp. Albedinis. J. Biol. Sci., 9: 594-600.
50. Broca, C, R. Gross, P. Petit, Y. Sauvaire and M. Manteghetti, et al, 1999. 4-Hydroxyisoleucine: Experimental evidence of its insulinotropic and antidiabetic properties. Am. J. Physiol., 277: E617-E623.
51. Broca, C, V. Breil, C. Cruciani-Guglielmacci, M. Manteghetti and C. Rouault et al, 2004. Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat. Am. J. Physiol. Endocrinol. Metabolism, 287: E463-E471.
52. Bufkhup, L. and S. Samappito, 2011. In vitro free radical scavenging and antimicrobial activity of some selected thai medicinal plants. Res. J. Med. Plant, 5: 254-265.
53. Chattopadhyay, P., S.S. Agrawal and A. Garg, 2006. Liver regenerative effect of Phyllanthus amarus Linn, against alcohol induced liver cell injury in partially hepatectomised albino rats. Int. J. Pharmacol., 2: 426-430.
54. Chattopadhyay, P., A. Garg, V.P. Varshey, A.K. Sharma and S.S. Agrawal, 2007. Increase insulin activity by Phyllanthus amarus linn on liver cell regeneration in partially hepatectomised albino rats. Res. J. Medicinal Plant 1: 17-20.
55. Choi, J.S., S.K. Lee, C.K Sung and J.H. Jung, 1996. Phytochemical study on Aloe vera. Arch. Pharmacal Res., 19: 163-167.
56. Clement S., S.S. Braifhwaite, M.F. Magee, A. Ahmann and E.P. Smith et al, 2004. Management of diabetes and hyperglycemia in hospitals. Diabetes Care, 27: 553-591.
57. Cooke, D.W. and L. Plotnick, 2008. Type 1 diabetes mellitus in pediatrics. Pediatr. Rev., 29: 374-385.
58. Costa, S.S., D.B. Oliveira, A.M. Manco, G.O. De Melo and J.L.P. Cordeiro et al, 2006. Plants composing the diet of marsh and pampas deer in the Brazilian pantanal wetland and their ethnomedicinal properties. J. Boil. Sci., 6: 840-846.
59. DaSilva, E.J., E. Baydoun and A. Badran, 2002. Biotechnology and developing world. Electron. J. Biotechnol., 5: 64-92.
60. Dadji, G.A.F., J.L. Tamesse and F.F. Boyom, 2011. Adulticidal effects of essential oils extracts from Capsicum annuum (solanaceae) Piper nigrum (piperaceae) and Zingiber officinale (zingiberaceae) onAnopheles gambiae (Diptera-Culicidea), vector of malaria. J. EntomoL, 8: 152-163.
61. Daisy, P., N.A. Rayan and D. Rajathi, 2007. Hypoglycemic and other related effects of Elephantopus scaber extracts on alloxan induced diabetic rats. J. Biol. Sci., 7: 433-437.
62. Daisy, P., R. Jasmine, S. Ignacimuthu and E. Murugan, A novel steroid from Elephantopus scaber L. an ethnomedicinal plant with antidiabetic activity. Phytomedicine, 16: 252-257.
63. Daradka, H., M.M. Almasad, W.S. Qazan, N.M. El-Banna and O.H. Samara, 2007. Hypolipidaemic effects of Citrullus colocynthisL. in rabbits. Pak. J. Biol. Sci., 10: 2768-2771.
64. Davis, R.H. and N.P. Maro, 1989. Aloe vera and gibberellins. Anti-inflammatory activity in diabetes. J. Am. Pediat. Med. Assoc., 79: 24-26.
65. Dawei, G., L. Qingwang, L. Ying, L. Zhihua and L. Zhiwei et al., 2007. Antidiabetic potential of oleanolic acid from Ligustrum lucidum Ait. Can. J. Physiol. Pharmacol, 85: 1076-1083.
66. Dehghan, A., A.A. Mahjoor, H. Bazyar and K. Zangili, Effects of silymarin and food restriction on hepatic and pancreatic functions in wistarrats. Asian J. Amm. Vet. Adv., 5: 136-142.
67. Dehghani, F. and M.R. Panjehshahin, 2006. The toxic effect of alcoholic extract of Citrullus colocynthis on rat liver. J. Pharmacol. Ther., 5: 117-119.
68. Delazar, A., S. Gibbons, A.R. Kosari, H. Nazemiyeh, M. Modarresi, L. Nahar and D. Satyajit, 2006. Flavone C-Glycosides and cucurbitacin glycosides from Citrullus collocynthis. DARU J. Pharmaceu. Sci., 14: 109-114.
69. Deshpande, A.D., M. Harris-Hayes and M. Schootman, 2008. Epidemiology of diabetes and diabetes-related complications. Phys. Ther., 88: 1254-1264.
70. Dodson, P.M., 2002. Hypertension and diabetes. Curr. Med. Res. Opin., 18: 48-57.
71. Dulger, B. and A. Gonuz, 2004. Antimicrobial activity of some Turkish medicinal plants. Pak. J. Biol. Sci., 7: 1559-1562.
72. Eizirik, D.L., M.L. Colli and F. Ortis, 2009. The role of inflammation in insulitis and [3-cell loss in type 1 diabetes. Nat. Rev. Endocrinol, 5: 219-226.
73. Ene, A.C., D.A. Ameh, H.O. Kwanashie, P.U. Agomo and S.E. Atawodi, 2008. Preliminary in vivo antimalarial screening of petroleum ether, chloroform and methanol extracts of fifteen plants grown in Nigeria. J. Pharmacol. Toxicol, 3: 254-260.
74. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, 1997. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care, 20: 1183-1197.
75. Fadhil, N.N., 2008. Herbal use for diabetes mellitus in Mosul: A study of characteristics and review of evidence. Iraqi Med. J., 54: 42-53.
76. Faiivar, T.N., A.H.M. Fard, S.S. Zahedani, M. Naden and S. Moud, 2006. Antituberculosis effect of Ocimum sanctum extracts in in vitro and macrophage culture. J. Medical Sci., 6: 348-351.
77. Farooqi, A.A. and N. Kumar, 2003. Recent Progress in Medicinal Plants. Ethanomedicine and Pharmacognosy II. Vol. 7, Stadium Press, USA.
78. Fatima, N, I.U. Siddiqui, F. Perveen and Z.T. Maqsood, 2004. Among few commonly used anti-diabetic herbs: Fenugreek is the best. Pak. J. Biol Sci., 7: 966-970.
79. Fernandes, N.P., C.V. Lagishetty, V.S. Panda and S.R. Naik, 2007. An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract. BMC Compl. AlternMed., 7: 29-37.
80. Fokou, E., M.B. Achu, G. Kansci, R. Ponka, M. Fotso, Tchiegang and F.M. Tchouanguep, 2009. Chemical properties of some cucurbitaceae oils from Cameroon. Pak. J. Nutr., 8: 1325-1334.
81. Fowden, L., H.M. Pratt and A. Smith, 1973. 4-Hydroxyisoleucine from seed of Trigonella foenum-graecum. Phytochemistry, 12: 1707-1711.
82. Gallagher, A.M., P.R. Flatt, G. Duffy and Y.H.A. Abdel-Wahab, 2003. The effects of traditional antidiabetic plants on in vitro glucose diffusion. Nutr. Res., 23: 413-424.
83. Gantait, S., N. Mandal, S. Bhattacharyya and P.K. Das, 2010. A novel strategy for in vitro conservation of Aloe vera L. through long term shoot culture. Biotechnology, 9: 326-331.
84. 5-sterols in the seeds of Cucurbita maxima. Phytochemistry, 23: 2925-2929.
85. Gessner, B., A. Voelp and M. Klasser, 1985. Study of the long-term action of a Ginkgo biloba extract on vigilance and mental performance as determined by means of quantitative pharmaco-EEG and psychometric measurements. Arzneimittel-Forschung, 35: 1459-1465.
86. Gray, A.M. and P.R. Flatt, 1999. Insulin-releasing and insulin-like activity of the traditional antidiabetic plant Coriandrum sativum (coriander). Br. J. Nutr., 81: 203-209.
87. Groop, L.C., 1992. Sulfonylureas in NIDDM. Diabetes Care, 15: 737-754.
88. Guerra, N.B., E. de Almeida Melo and J.M. Filho, 2005. Antioxidant compounds from coriander (Coriandrum sativum L.) efheric extract. J. Food Compos. Anal, 18: 193-199.
89. Guignard, A.P., J. Oberholzer, P.Y. Benhamou, S. Touzet and P. Bucher et al, 2007. Cost analysis of human islet transplantation for the treatment of type 1 diabetes in the Swiss-French Consortium GRAGIL. Diabetes Care, 27: 895-900.
90. Gurudeeban, S., K. Satyavani and T. Ramanathan, 2010. Bitter apple (Citrullus colocynthis): An overview of chemical composition and biomedical potentials. Asian J. Plant Sci., 9: 394-401.
91. Habib, M.Y., M.S. Islam, M.A. Awal and M.A. Khan, 2005. Herbal products: A novel approach for diabetic patients. Pak. J. Nutr., 4: 17-21.
92. Hadizadeh, I, B. Peivastegan and M. Kolahi, 2009. Antifungal activity of nettle (Urtica dioica L.), colocynth (Citrullus colocynthis L. schrad), oleander (Nerium oleander L.) and konar (Ziziphus spina-christiL.) extracts on plants pathogenic fungi. Pak. J. Biol. Sci., 12: 58-63.
93. Hamayun, M., S.A. Khan, I. Iqbal, G. Rehman, T. Hayat and M.A. Khan, 2005. Ethnobotanical profile of Utror and Gabral Valleys, District Swat, Pakistan. Efhnobot. Leaflets, 10: 40-45.
94. Hamid, M., S.P.M. Bohari, M.S. Bastami, A.M. AH, N.M. Mustapha and K. Shari, 2008. Evaluation of the insulinotrophic activity of Malaysian traditional plants extract. J. Boil. Sci., 8: 201-204.s
95. Harinantenaina, L., M. Tanaka, S. Takaoka, M. Oda, O. Mogami, M. Uchida and Y. Asakawa, 2006. Momordica charantia constituents and antidiabetic screening of the isolated major compounds. Chem. Pharm. Bull, 54: 1017-1021.
96. 2 cells. Asian J. Biochem., 2: 421-426.
97. Hasan, M.M., S.P. Chowdhury, S. Alam, B. Hossain and M.S. Alam, 2005. Antifungal effects of plant extracts on seed-borne fungi of wheat seed regarding seed germination, Seedling health and vigour index. Pak. J. Biol. Sci., 8: 1284-1289.
98. Hasan, T.N., S.N. Ahmed, S.M.M. Aalam, C. Kumar and G. Shafi, 2007. Evaluation of cichorium extract for the growth supporting property in rat hepatocyte primary culture. Asian J. Plant Sci., 6: 431-434.
99. Hasani-Ranjbar, S., B. Larijani and M. Abdollahi, 2008. A systematic review of Iranian medicinal plants useful in diabetes mellitus. Arch. Med. Sci., 4, 3: 285-292.
100. Hasanloo, T., R.A. Khavari-Nejab, E. Majidi and M.R.S. Ardekani, 2005. Analysis of flavonolignans in dried fruits of Silybum marianum (L.) gaertn from Iran. Pak. J. Biol. Sci., 8: 1778-1782.
101. Hashemi, S.R., I. Zulkifli, M. Hair-Bejo, A. Farida and M.N. Somchit, 2008. Acute toxicity study and phytochemical screening of selected herbal aqueous extract in broiler chickens. Int. J. Pharmacol., 4: 352-360.
102. Hassan, S.M.E., M. S. Rahman, M.R. Amin, U.K. Majumdar and H.F. El Taj, 2001. Study of ginger on root-knot disease of Brinjal. J. Biological Sci., 1: 560-562.
103. Hayat A.S. and N. Shaikh, 2010. Barriers and myths to initiate insulin therapy for type 2 diabetes mellitus at primary health care centre of Hyderabad district. World Applied Sci., 8: 66-72.
104. Hemalatha, R., K.N. Babu, M. Karthik, R. Ramesh, D. Kumar and P.U Kumar, 2011. Immunomodulatory activity and Thl/Th2 cytokine response of ocimum sanctum in myelosuppressed Swiss Albino mice. Trends Med. Res., 6: 23-31.
105. Hemmerle, H., H.J. Burger, P. Below, G. Schubert and R. Rippel et al, 1997. Chlorogenic acid and synthetic chlorogenic acid derivatives: Novel inhibitors of hepatic glucose-6-phosphate translocase. J. Med. Chem., 40: 137-145.
106. Herawati, 2010. The effect of feeding red ginger as phytobiotic on body weight gain. Int. J. Poult, 9: 963-967.
107. Herold, K.C., W. Hagopian, J.A. Auger, E. Poumian-Ruiz and L. Taylor et al, 2002. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. New Engl. J. Med., 346: 1692-1698.
108. Ho, W.Y., H. Ky, S.K. Yeap, R.A. Rahim, A.R. Omar, L. Ho and N.B. Alitheen, 2009. Traditional practice, bioactivities and commercialization potential of Elephantopus scaber Linn. J. Med. Plants Res., 3: 1212-1221.
109. Hoareau, L. and E.J. Dasilva, 1999. Medicinal plants: A re-emerging health aid. Elect. J. Biotechnol., 2: 56-70.
110. Hoffman, L., C. Nolan, J.D. Wilson, J.J.N. Oats and D. Simmons, 1998. Gestational diabetes mellitus- management guidelines. The Australasian diabetes in pregnancy society. Med. J. Aust, 169: 93-97.
111. Horiuchi, S., N. Araki and Y. Morino, 1991. Immunochemical approach to characterize advanced glycation end products of the Maillard reaction. Evidence for the presence of a common structure. J. Biol. Chem., 266: 7329-7332.
112. Huang, C.L., M.T. Hsieh, W.C. Hsieh, A.P. Sagare and H.S. Tsay, 2000. In vitro propagation of limonium wrightii (Hance) Ktze. (Plumbaginaceae), an ethnomedicinal plant, from shoot-tip, leaf-and inflorescence-node explants. In Vitro Cell. Dev. BioL-Plant, 36: 220-224.
113. Huseini, H.F., B. Larijani, R. Heshmat, H. Fakhrzadeh, B. Radjabipour, T. Tohat and M. Raza, 2006. The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: A randomized, double-blind, place bo-controlled, clinical trial. Phytother. Res., 20: 1036-1039.
114. Hussam, E.H.M.A., K. Jamil and M. Rao, 2001. Hypoglycaemic, hypolipidemic and antioxidant properties of tulsi (Ocimum sanctum Linn.) on streptozotocin induced diabetes in rats. Indian J. Clin Biochem., 16: 190-194.
115. Hussain, J., A.L. Khan, N.U. Rehman, Zainullah, F. Khan, S.T. Hussain and Z.K. Shinwari, 2009. Proximate and nutrient investigations of selected medicinal plants species of Pakistan. Pak. J. Nutr., 8: 620-624.
116. Idu, M. and H.I. Onyibe, 2007. Medicinal plants of Edo State, Nigeria. Res. J. Med. Plant, 2: 32-41.
117. Ige, S.F., R.E. Akhigbe, A.A. Adewale, J.A. Badmus and S.B. Olaleye et al, 2011. Effect of Allium cepa (Onion) extract on cadmium-induced nephrotoxicity in rats. Kidney Res. J., 1: 41-47.
118. Ishtiaq, M., W. Hanif, M.A. Khan, M. Ashraf and A.M. Butt, 2007. An ethnomedicinal survey and documentation of important medicinal folklore food phytonims of flora of Samahni valley, (Azad Kashmir) Pakistan. Pak. J. Biol. Sci., 10: 2241-2256.
119. Islam, M.S., M.B. Alam, R. Zahan, G.C. Sarker and N.S. Chowdhury et al, 2011. In vitro antioxidant and anti-neoplastic activities of Ocimum sanctum leaves in ehrlich ascites carcinoma bearing mice. Int. J. Cancer Res., (In Press).
120. Jaleel, C.A., R. Gopi and R. Paneerselvam, 2009. Alterations in non-enzymatic antioxidant components of Catharanthus roseus exposed to paclobutrazol, gibberellic acid and Pseudomonas fluorescens. Plant Omics J., 2: 30-40.
121. Jamaluddin, F., S. Mohamed and Md. NordinLajis, 1994. Hypoglycaemic effect oiParkia speciosa seeds due to the synergistic action of [3-sitosterol and stigmasterol. Food Chem., 49: 339-345.
122. 2 enrichment on the differentiation of regenerated plant. Biotechnology, 6: 101-104.
123. Jan, G., M.A. Khan and F. Gul, 2009. Ethnomedicinal plants used against jaundice in dir Kohistan valleys (NWFP), Pakistan. Ethnobotanical Leaflets, 13: 1029-1041.
124. Jang, S.M., S.T. Yee, J. Choi, M.S. Choi and G.M. Do et al, 2009. Ursolic acid enhances the cellular immune system and pancreatic [3-cell function in streptozotocin-induced diabetic mice fed a high-fat diet. Int. Immunopharmacol., 9: 113-119.
125. Jarald, E.E., E. Sheeja, S. Motwani, K.R. Dutt and R.K. Goel, 2008. Comparative evaluation of antihyperglycaemic and hypoglycaemic activity of various parts of Catharanthus roseus Linn. Res. J. Medicinal Plant, 2: 10-15.
126. Jasmine, R. and P. Daisy, 2007. Effect of crude extract and fractions from Elephantopus scaber on hyperglycemia in streptozotocin-diabetic rats. Int. J. Biol. Chem., 1: 111-116.
127. Jaya, A., P. Shanthi and P. Sachdanandam, 2010. Hypoglycemic effect of Semecarpus anacardium in streptozotocin induced diabetic rats. Int. J. Pharmacol, 6: 435-443.
128. Jayaprakasam, B., S.K. Vareed, L.K. Olson and M.G. Nair, 2005. Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits. J. Agric. Food Chem., 12: 28-31.
129. Johji, Y., M. Michihiko, H.Q. Rong, M. Hisashi and F. Hajime, 1988. The anti-ulcer effect in rats of ginger constituents. J. Ethnopharmacol, 23: 299-304.
130. Joseph, B. and S.J. Raj, 2011. An overview: Pharmacognostic properties of Phyllanthus amarus Linn. Int. J. Pharmacol, 7: 40-45.
131. Joshi, B., G.P. Sah, B.B. Basnet M.R. Bhatt and D. Sharma et al, 2011. Phytochemical extraction and antimicrobial properties of different medicinal plants: Ocimum sanctum (Tulsi), Eugenia caryophyllata (Clove), Achyranthes bidentata (Datiwan) and Azadirachta indica (Neem). J. Microbiol. Antimicrobials, 3: 1-7.
132. Jung, M., M. Park, H.C. Lee, Y. Kang, E.S. Kang and S.K. Kim, 2006. Antidiabetic agents from medicinal plants. Curr. Med. Chem., 13: 1203-1218.
133. Kahn, S.E., R.L. Hull and K.M. Utzschneider, 2006. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature, 44: 840-846.
134. Kalemba, D., D. Kusewicz and K. Swiader, 2002. Antimicrobial properties of the essential oil of Artemisia asiatica Nakai. Phytofher. Res., 16: 288-291.
135. Kamboj, V.P., 2000. Herbal medicine. Curr. Sci., 78: 35-39.
136. Kansal, L., V. Sharma, A. Sharma, S. Lodi and S.H. Sharma, 2011. Ameliorating effect of coriandrum sativum extracts on hematological and immunological variables in an animal model of lead intoxication. J. Pharmacy Allied Health Sci., (In Press).
137. Kesari, A.N., R.K. Gupta and G. Wattal, 2005. Hypoglycemic effects of Murraya koenigii on normal and alloxan-diabetic rabbits. J. Ethnopharmacol., 97: 247-251.
138. Kesari, A.N., S. Kesari, S.K. Singh, R.K. Gupta and G. Watal, 2007. Studies on the glycemic and lipidemic effect of Murraya koenigii in experimental animals. J. Ethnopharmacol., 112: 305-311.
139. Khafagy, S.M. S.A. Gharbo and T.M. Sarg, 1971. Phytochemical investigation of Artemisia herba alba. Planta Med., 20: 90-96.
140. Khan, A. and R.A. Anderson, 2003. Insulin Potentiating Factor (IPF) present in foods, species and natural products. Pak. J. Nutr., 2: 254-257.
141. Khan, N, M.S. Alam and U.K. Nath, 2004. In vitro regeneration of garlic through callus culture. J. Biological Sci., 4: 189-191.
142. Khan, S., R.K. Smgla and M.Z. Abdin, 2011. Assessment of phytochemical diversity in Phyllanthus amarus using HPTLC Fingerprints. Indo-Global J. Pharmaceut. Sci., 1: 1-12.
143. Khan, S.W. and S. Khatoon, 2008. Ethnobotanical studies on some useful herbs of Haramosh and Bugrote valleys in Gilbit, Northern areas of Pakistan. Pak. J. Bot, 40: 43-58.
144. Khanna, P., S.C. Jain, A. Panagariya, V.P. Dixit 1981. Hypoglycemic activity of polypeptide-P from a plant source. J. Nat. Prod., 44: 648-655.
145. Kim, H.Y., B.H. Moon, H.J. Lee and D.H. Choi, 2004. Flavonol glycosides from the leaves of Eucommia ulmoides O. with glycation inhibitory activity. J. Enthnopharmacol., 93: 227-230.
146. Kolawole, O.T., F.E. Abiona, S.O. Kolawole, A.A. Ayankunle and O.I. Olaniran, 2011. Effect of momordica charantia fruit extract on normal and alloxan-diabetic rats. Int. J. Pharmocol., (In Press).
147. Kothai, R., B. Arul, K.S. Kumar and A.J. Christina, 2005. Hypoglycemic and antiperglycemic effects of Semecarpus Anacardium linn in normal and alloxan-induced diabetic rats. J. Herb Pharmacother., 5: 49-56.
148. Kousar, S., M.A. Sheikh, M. Asghar and R. Rashid, 2008. Effect of onion (Allium cepa L.) extract on maillard reaction under in vitro conditions. Pak. J. Agric. Sci., 45: 103-106.
149. Kubola, J. and S. Siriamornpun, 2008. Phenolic contents and antioxidant activities of bitter gourd (Momordica charantia L.) leaf, stem and fruit fraction extracts in vitro. Food Chem., 110: 881-890.
150. Kumar, G.R. and K.P. Reddy, 1999. Reduced nociceptive responses in mice with alloxan induced hyperglycemia after garlic (Allium sativum Linn.) treatment. Indian J. Exp. Biol., 37: 662-666.
151. Kumari, K, B.C. Mathew and K.T. Augusti, 1995. Antidiabetic and hypolipidemic effects of S-mefhyl cysteine sulfoxide isolated from Allium cepa Linn. Ind. J. Biochem. Biophys., 32: 49-54.
152. Kumari, K. and K.T. Augusti, 2007. Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol fed rats. J. Ethnopharmacol., 109: 367-371.
153. Laid, M., M.E.F. Hegazy, A.A. Ahmed, K. AH, D. Belkacemi and S. Ohta, 2008. Sesquiterpene lactones from Algerian Artemisia herba-alba. Phytochem. Lett, 1: 85-88.
154. Lakshmi, B.V.S. and M. Sudhakar, 2010. Protective effect of Zingiber officinale on gentamicin-induced nephrotoxicity in rats. Int. J. Pharmacol., 6: 58-62.
155. Lefebvre, P., 2005. Diabetes yesterday, today and tomorrow. The action of the international diabetes federation. Rev. Med. Liege, 60: 273-277.
156. Liu, Y., Z. Ali and I.A. Khan, 2008. Cucurbitane-type triterpene glycosides from the fruits of momordica charantia. Planta Med, 74: 1291-1294.
157. Madani, H., M. Talebolhosseini, S. Asgary and G.H. Naderi, 2008. Hepatoprotective activity of Silybum marianum and Cichorium intybus against thioacetamide in rat. Pak. J. Nutr., 7: 172-176.
158. Maghrani, M., N.Z. Zeggwagh, A. Lemhadri, M.E. Amraoui, J.B. Michel and M. Eddouks, 2004. Study of the hypoglycaemic activity of Fraxinus excelsior and Silybum marianum in an animal model of type 1 diabetes mellitus. J. Ethnopharmacol., 91: 309-316.
159. Majumdar, S.H., G.S. Chakraborthy and K.S. Kulkarni, 2008. Medicinal potentials of Semecarpus anacardium nut-A review. J. Herbal Med. Toxicol., 2: 9-13.
160. Malaisse, W.J., 2003. Pharmacology of the meglitinide analogs: New treatment options for type 2 diabetes mellitus. Treat. Endocrinol., 2: 401-414.
161. Malihi, F., A. Hosseini-Tabatabaei, H. Esmaily, R. Khorasam, M. Baeen and M. Abdollahi, 2009. Improvement of inflammatory and toxic stress biomarkers by silymarin in a murine model of type one diabetes mellitus. Cent. Eur. J. Biol, 4: 369-380.
162. Malik, M.F., M. Nawaz and Z. Hafeez, 2003. Evaluation of crop production, management techniques and economic status of onion in Balochistan, Pakistan. Pak. J. Agron., 2: 70-76.
163. Malik, S., M. Zia, Riaz-ur-Rehman and M. Fayyaz Chaudhary, 2007. In vitro plant regeneration from direct and indirect organogenesis of Memordica charantia. Pak. J. Biol. Sci., 10: 4118-4122.
164. Malu, S.P., G.O. Obochi, E.N. Tawo and B.E. Nyong, 2009. Antibacterial activity and medicinal properties of ginger (zingiber officinale). Global J. Pure Applied Sci., 154: 365-368.
165. Maritim, A.C., R.A. Sanders and J.B. Watkins, 2003. Diabetes, oxidative stress and antioxidants: A review. J. Biochem. Mol. Toxicol., 17: 24-38.
166. Marwat S.K., M.A. Khan, A. Khan, M. Ahmad, M. Zafar, F.U. Rehman and S. Sultana, 2009. Vegetables mentioned in the Holy Qura'n and Ahadith and their ethnomedicinal studies in Dera Ismail Khan, N.W.F.P., Pakistan. Pak. J. Nutr., 8: 530-538.
167. Masaadeh, H.A., W.A. Hayajneh and N.M. Momani, 2006. Microbial ecology of dental plaques of Jordanian patients and inhibitory effects of Allium sativum and Allium cepa L. extracts. J. Medical Sci., 6: 650-653.
168. Mehri, A., S.H. Ranjbar, B. Larijani and M. Abdollahi, 2011. A systematic review of efficacy and safety of Urtica dioica in the treatment of diabetes. Int. J. Pharmacol, 7: 161-170.
169. Meinert, C.L., G.L. Knatterud, T.E. Prout and C.R. Klimt, 1970. A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. II. Mortality results. Diabetes, 19: 789-830.
170. Memon, U., A.H. Brohi, S.W. Ahmed, I. Azhar and H. Bano, 2003. Antibacterial screening of Citrullus colocynthis. Pak. J. Pharm. Sci., 16: 1-6.
171. Mikail, H.G., 2010. Phytochemical screening, elemental analysis and acute toxicity of aqueous extract of Allium sativum L. bulbs in experimental rabbits. J. Med. Plants Res., 4: 322-326.
172. Milala, J., K. Grzelak, B. Krol, J. Juskiewicz and Z. Zdunczyk, 2009. Composition and properties of chicory extracts rich in fructans and polyphenols. Polish J. Food Nutr. Sci., 59: 35-43.
173. Mishra, P. and S. Mishra, 2011. Study of antibacterial activity of Ocimum sanctum extract against gram positive and gram negative bacteria. Am. J. Food Technol, 6: 336-341.
174. Misra, S.D., M. Rajkumar, M. Chhanda and G. Debidas, 2006. Protective response of methanolic extract of Ocimum sanctum, Withania somnifera and Zingiber officinalis on swimming-induced oxidative damage on cardiac, skeletal and brain tissues in male rat: A duration dependent study. Int. J. Pharmacol, 2: 647-655.
175. Mmereole, F.U.C., 2011. Evaluation of the dietary inclusion of aloe vera as an alternative to antibiotic growth promoter in broiler production. Pak. J. Nutr., 10: 1-5.
176. Mohamed, A.M. and N. S. Metwally, 2009. Antiaflatoxigenic activities of some plant aqueous extracts against aflatoxin-bl induced renal and cardiac damage. J. Pharmacol. Toxicol, 4: 1-16.
177. Mohan, V.R., P. Chenthurpandy and C. Kahdass, 2010. Pharmacognostic and phytochemical investigation of Elephantopus scaber L. (Asteraceae). J. Pharm. Sci. Technol, 2: 191-197.
178. Moorthy, M., C. Mehala, S. Saravanan and S.C. Edwin, 2009. Aloe vera in white leghorn layer diet. Int. J. Poult. Sci., 8: 706-709.
179. Mulinacci, N, M. Innocenti, S. Gallori, A. Romani, G. La Marca and F.F. Vincieri, 2001. Optimization of the chromatographic determination of polyphenols in the aerial parts of Cichorium intybus L. Chromatographia, 54: 455-461.
180. Mullan, B.A., I.S. Young, H. Fee and D.R. McCance, 2002. Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes. Hypertension, 40: 804-809.
181. Muntean, E. and I. Rotar, 2010. HPLC assesment of provitamin a carotenoids from Cucurbita maxima duch. ex. lam. (mariba cultivar) fruits. Res. J. Agric. Sci., 42: 517-520.
182. Mustafa, N.R. and R. Verpoorte, 2007. Phenolic compounds in Catharanthus roseus. Phytochem. Rev., 6: 243-258.
183. Nagori, B.P. and R. Solanki, 2011. Role of medicinal plants in wound healing. Res. J. Med. Plant, 5: 392-405.
184. Najafi, S., N. Sanadgol, B.S. Nejad, M.A. Beiragi and E. Sanadgol, 2010. Phytochemical screening and antibacterial activity of Citrullus colocynthis (Linn.) Schrad against Staphylococcus aureus. J. Med. Plants Res., 4: 2321-2325.
185. Nakamura, S., Z. Makita, S. Ishikawa, K. Yasumura and W. Fujiix et al, 1997. Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation. Diabetes, 46: 895-899.
186. Nalawade, S.M. andH.S. Tsay, 2004. In vitro propagation of some important Chinese medicinal plants and their sustainable usage. In vitro Cell. Dev. Biol.-Plant, 40: 143-154.
187. Nammi, S., M.K. Boini, S.D. Lodagala and R.B.S. Behara, 2003. The juice of fresh leaves of Catharanthus roseus Linn. Reduces blood glucose in normal and alloxan diabetic rabbits. Biomed. Central, 3: 1-4.
188. Nathan, D.M., J.B. Buse, M.B. Davidson, E. Ferrannini, R.R. Holman, Ro. Sherwin and B. Zinman, 2009. Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy. Diabetes Care, 31: 193-203.
189. Neogi, U., R. Saumya and B. Irum, 2007. In vitro combinational effect of bio-active plant extracts on common food borne pathogens. Res. J. Microbiol., 2: 500-503.
190. Ni, Y., D. Turner, K.M. Yates and L. Tizard, 2004. Isolation and characterization of structural components of Aloe vera L. leaf pulp. Int. Immunopharmacol., 4: 1745-1755.
191. Nicasio, P., L. Aguilar-Santamaria, E. Aranda, S. Ortiz and M. Gonzalez, 2005. Hypoglycemic effect and chlorogenic acid content in two Cecropia species. Phytotherapy Res., 19: 661-664.
192. Nidiry, E.S.J., G. Ganeshan and A.N. Lokesha, 2011. Antifungal activity of some extractives and constituents of Aloe vera. Res. J. Med. Plant, 5: 196-200.
193. Nifhya, K.S. and B. Ramachandramurty, 2007. Screening of some selected spices with medicinal value for Cu (Il)-ninhydrin positive compounds. Int. J. Biol. Chem., 1: 62-68.
194. Nmila, R., R. Gross, H. Rchid, M. Roye and M. Manteghetti et al, 2000. Insulinotropic effect of Citrullus colocynthis fruits extract. Planta Med, 66: 418-423.
195. Nobakht, M., S. Asalgo, NR. Rooshandel, K. Mousavizadeh and N. Najafzadeh, 2011. Effects of silibinin on hair follicle stem cells differentiation to neural-like cells. Am. J. Biochem. Mol. Biol., 1: 212-222.
196. Odo, B.I., B.U. Ekenyem and A.C. Nwamo, 2010. Effects of aloe vera as leaf protein concentrate on growth performance of cockerels. Int. J. Poult. Sci., 9: 426-428.
197. Ogungbe, TV. and A.O. Lawal, 2008. The protective effects of ethanolic extract of garlic and ascorbic acid on cadmium-induced oxidative stress. J. Boil. Sci., 8: 181-185.
198. Okamura, N, N. Hine, Y. Tateyama, M. Nakazawa, T. Fujioka, K. Mirmhi and A. Yagi, 1997. Three chromones of Aloe vera leaves. Phytochemistry, 45: 1511-1513.
199. Okamura, N, N. Hine, Y. Tateyama, M. Nakazawa, T. Fujioka, K. Mihashi and A. Yagi, 1998. Five chromones from Aloe vera leaves. Phytochemistry, 48: 219-223.
200. Olusanmi, M.J. and J.E. Amadi, 2009. Studies on the antimicrobial properties and phytochemical screening of garlic (Allium sativum) extracts. Efhnobotanical Leaflets, 13: 1186-1196.
201. Oparaeke, A.M. and G.C. Kuhiep, 2006. Toxicity of powders from indigenous plants against Sitophilus zeamais motsch on stored grains. J. Entomol, 3: 216-221.
202. Oyagbemi, A.A., A.B. Saba and R.O.A. Arowolo, 2008. Safety evaluation of prolonged administration of Stresroak ® in grower cockerels. Int. J. Poult. Sci., 7: 574-578.
203. Panda, S. and A. Kar, 2007. Antidiabetic and antioxidative effects of Annona squamosa leaves are possibly mediated through quercetin-3-O-glucoside. Biofactors, 31: 201-210.
204. Panda, S., M. Jafn, A. Kar and B.K. Meheta, 2009. Thyroid inhibitory, antiperoxidative and hypoglycemic effects of stigmasterol isolated from Butea monosperma. Fitoterapia, 80: 123-126.
205. Panesar, P.S. and C. Shinde, 2011. Effect of Storage on Syneresis, pH, Lactobacillus acidophilus Count, Bifidobacterium bifidum Count of Aloe vera Fortified Probiotic Yoghurt. Curr. Res. Dairy Sci. (In Press).
206. Pathmanafhan, M.K., K. Ufhayarasa, J.P. Jeyadevan and E.C. Jeyaseelan, 2010. In vitro antibacterial activity and phytochemical analysis of some selected medicinal plants. Int. J. Pharmaceut. Biolog. Arch., 1: 291-299.
207. Patrick-Iwuanyanwu, K.C., M.O. Wegwu and E.O. Ayalogu, 2007. Prevention of CCL-induced liver damage by ginger, garlic and vitamin E. Pak. J. Biol. Sci., 10: 617-621.
208. Pavaraj, M., V. Balasubramanian, S. Baskaran and P. Ramasamy, 2011. Development of immunity by extract of medicinal plant ocimum sanctum on common carp Cyprinus carpio (L.). Res. J. Immunol. (In Press).
209. Perez, Y.Y., E. Jimenez-Ferrer, A. Zamilpa, M. Hernandez-Valencia, F.J. Alarcon-Aguilar, J. Tortoriello and R. Roman-Ramos, 2007. Effect of a polyphenol-rich extract from Aloe vera gel on experimentally induced insulin resistance in mice. Am. J. Chinese Med, 35: 1037-1046.
210. Philip, K, S.K. Sinniah and S. Mumandy, 2009. Antimicrobial Peptides in Aqueous and Ethanolic Extracts from Microbial, Plant and Fermented Sources Biotechnology, 8: 248-253.
211. Prakash, O., G.N. Singh, R.M. Singh, S.C. Mathur, M. Bajpai and S. Yadav, 2008. Protective effect of a herbal formula against carbontetrachloride induced hepatotoxicity. Int. J. Pharmacol., 4: 282-286.
212. Prasad, V., V. Jam and A.K. Dorle, 2006. Evaluation of Momordica charantia ghrita for immunomodulatory activity. J. Plant Sci., 1: 80-85.
213. Prasad, S.K., A. Kulshreshtha and T.N. Qureshi, 2009. Antidiabetic activity of some herbal plants in streptozotocin induced diabetic Albino rats. Pak. J. Nutr., 8: 551-557.
214. Premanath, R., J. Sudisha, N.L. Devi and S.M. Aradhya, 2011. Antibacterial and Anti-oxidant activities of Fenugreek (Trigonella foenium graecum L.) leaves. Res. J. Med. Plant,
215. Price, K.R, J.R. Bacon and MJ.C. Rhodes, 1997. Effect of storage and domestic processing on the content and composition of flavonol glucosides in onion (Allium cepa). J. Agnc. Food Chem., 45: 938-942.
216. Pritam, A. and P.G. Kale, 2007. Alteration in the antioxidant potential of Aloe vera due to fungal infection. Plant Pathol. J., 6: 169-173.
217. Pushparaj, P.N., H.K. Low, J. Manikandan., B.K.H. Tan and C.H. Tan, 2007. Anti-diabetic effects of Cichorium intybus in streptozotocin-induced diabetic rats. J. Ethnopharmacol., Ill: 430-434.
218. Qaseem, A., L.L. Humphrey, R. Chou, V. Snow and P. Shekelle, 2011. Use of intensive insulin therapy for the management of glycemic control in hospitalized patients: A clinical practice guideline from the American college of physicians. Ann. Internal Med., 154: 260-267.
219. Raghavendra, M.P., S. Satish and A. Raveesha, 2006. Phytochemical analysis and antibacterial activity of Oxalis corniculata, an known medicinal plant. My Sci., 1: 72-78.
220. Rahimi, R., S. Nikfar, B. Laiijani and M. Abdollahi, 2005. A review on the role of antioxidants in the management of diabetes and its complications. Biomed. Pharmacother., 59: 365-373.
221. Rahman, M.S., M.M.H. Khan and M.A.H.M. Jamal, 2010. Anti-bacterial evaluation and minimum inhibitory concentration analysis of Oxalis corniculata and Ocimum santum against bacterial pathogens. Biotechnology, 9: 533-536.
222. Rahman, M.W., M. Mostofa, S.A. Sardar, M.R. Sultana, M.M. Haque and M.E. Choudhury, 2005. Investigation of comparative hypoglycemic effect of neem (Azadirachta indica), karala (Momordica charantea) and nayantara (Cathranthus roseus) with glibenclamide on rat. Int. J. Pharmacol., 1: 257-260.
223. Rahmatullah, M., A.K. Das, A.H. Mollik, R. Jahan, M. Khan, T. Rahman and M.H. Chowdhury, 2009. An ethnomedicinal survey of Dhamrai sub-district in Dhaka District, Bangladesh. American-Eurasian J. Sustainable Agnc, 3: 881-888.
224. Rai, V., U. Lyer and U.V. Mam, 1997. Effect of Tulasi Ocimum sanctum leaf powder supplementation on blood sugar levels serum lipids and tissue lipids in diabetic rats. Plant Foods HumanNut, 50: 9-16.
225. Rajasekaran, S. and D. Sathishsekar, 2007. Therapeutic evaluation of Aloe vera leaf gel extract on glycoprotein components in rats with streptozotocin diabetes. J. Pharmacol. Toxicol., 2: 380-385.
226. Raju, J., D. Gupta, A.R. Rao, P.K. Yadava and N.Z. Baquer, 2001. Trigonella foenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic and lipogenic enzymes. Mol. Cell Biochem., 224: 45-51.
227. Ramachandran, A., R.C. Ma and C. Snehalatha, 2010. Diabetes in Asia. Lancet 375: 408-418.
228. Raman, A. and C. Lau, 1996. Anti-diabetic properties and phytochemistry Momordica charantia L. (Cucurbitaceae). Phytomedicine, 2: 349-362.
229. Ramanathan, T., S. Gurudeeban and K. Satyavani, 2011. Local anesthetic effect of Citrullus colocynthis on rana hexadactyla. Res. J. Med. Plant, 5: 338-342.
230. Rana, A.Y.K.M.M., J.A. Khanam and M. Asad-Ud-Daula, 2004. Antineoplastic screening of some medicinal plants against ehrlich ascites carcinoma in mice. J. Med. Sci., 4: 142-145.
231. Rani, P.U, andP. Devanand, 2011. Efficiency of Different Plant Foliar Extracts on Grain Protection and Seed Germination in Maize Res. J. Seed Sci., 4: 1-14.
232. Rifat-uz-Zaman, A.M. Shoaib and K.M. Shafiq, 2006a. In vitro antibacterial screening of Anethum graveolens L. fruit Cichorium intybus L. Leaf, Plantago ovata L. seed husk and Polygonum viviparum L. root extracts againstHelibacter pylori. Int. J. Pharmacol., 2: 674-677.
233. Rifat-uz-Zaman, M.S. Akhtar and M.S. Khan, 2006b. Anti-ulcerogenic screening of Cichorium intybus L. leaf in Indomethacin treated rats. Int. J. Pharmacol., 2: 166-170.
234. Ripsm, CM., H. Kang and R.J. Urban, 2009. Management of blood glucose in type 2 diabetes mellitus. Am. Family Physician, 79: 29-36.
235. Riserus, U, W.C. Willet and F.B. Hu, 2009. Dietary fats and prevention of type 2 diabetes. Prog. Lipid Res., 48: 44-51.
236. Rose, F., 1981. The Wild Flower Key: Guide to Plant Identification in the Field, With and Without Flowers: Over 1400 Species. Frederick Warne and Co., London.
237. Rose, P., M. Whiteman, P.K. Moore and Z.Y. Zhu, 2005. Bioactive S-alk(en)yl cysteine sulphoxide metabolites in the genus Allium: The chemistry of potential therapeutic agents. Nat. Prod. Rep., 22: 351-368.
238. Ryan, E.A., J.R. Lakey, R.V. Rajotte, G.S. Korbutt and T. Kin et al, 2001. Clinical outcomes and insulin secretion after islet transplantation with the edmonton protocol. Diabetes, 50: 710-719.
239. Ryder, J.W., CP. Portocarrero, X.M. Song, L. Cui and M. Yu et al., 2001. Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action and UCP-2 gene expression. Diabetes, 50: 1149-1157.
240. Safiyeh, S., F. Baijani Fathallah, N. Vahid, N. Hossine and S. Sadee Habib, 2007a. Antidiabetic effect of Equisetum arvense L. (Equisetaceae) in streptozotocin-induced diabetes in male rats. Pak. J. Biol. Sci., 10: 1661-1666.
241. Safiyeh, S., F. Fathallah, N. Vahid, S.S. Habib and N. Nabat, 2007b. Effect of Equisetum arvense L. (Equisetaceae) in microalbuminuria and creatinine excretion in streptozotocin-induced diabetes in male rats. Int. J. Pharmacol., 3: 155-159.
242. Saha, P., A. Bala, B. Kar, S. Naskar, U.K. Mazumder, P.K. Haldar and M. Gupta, 2011. Antidiabetic activity oiCucurbita maxima aerial parts. Res. J. Med. Plant, 5: 577-586.
243. Salido, S., L. Valenzuela, J. Altarejos, M. Nogueras, A. Sanchez and E. Cano, 2004. Composition and infraspecific variability of Artemisia herba-alba from southern Spain. Biochem. Syst. Ecol., 32: 265-277.
244. Salpeter, S., E. Greyber, G. Pasternak and E. Salpeter, 2006. Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. Cochrane Database Syst. Rev. 10.1002/14651858.CD002967
245. Sandhu, N.S., S. Kaur and D. Chopra, 2010. Equietum arvense: Pharmacology and phytochemistry-a review. Asian J. Pharm. Clin. Res., 3: 146-150.
246. Saravanan, T. and V. Valluvaparidasan, 2001. Fungitoxic effect of biocontrol agents and plant extracts on seed borne fungi of sorghum (Sorghum bicolor (L.) Moench). Pak. J. Biol. Sci., 4: 676-678.
247. Sarkhail, P., S. Rahmanipour, S. Fadyevatan, A. Mohammadirad and G. Dehghan et al, 2007. Antidiabetic effect of Phlomis anisodonta: Effects on hepatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes. Pharmacol. Res., 56: 261-266.
248. Sathishsekar, D. and S. Rajasekaran, 2007. Protective role of Momordica charantia seeds extract on membrane bound ATPases and lysosomal hydrolases in rats with streptozotocin diabetes. J. Plant Sci., 2: 293-301.
249. Satyavani, K, T. Ramanafhan and S. Gurudeeban, 2011a. Effect of plant growth regulators on callus induction and plantlet regeneration of bitter apple (Citrullus colocynthis) from stem explants. Asian J. Biotechnol, 3: 246-253.
250. Satyavani, K, T. Ramanafhan and S. Gurudeeban, 2011b. Plant mediated synthesis of biomedical silver nanoparticles by using leaf extract of Citrullus colocynthis. Res. J. Nanosci. Nanotechnol.,
251. Sauvaire, Y., P. Petit C. Broca, M. Manteghetti and Y. Baissac et al, 1998. 4-hydroxyisoleucine: A novel amino acid potentiator of insulin secretion. Diabetes, 47: 206-210.
252. Semalty, M., A. Semalty, G.P. Joshi and M.S.M. Rawat, 2009. Comparison of in vitro antioxidant activity of Trigonella foenum-graecum and T. corniculata Seeds. Res. J. Phytochem., 3: 63-67.
253. Semalty, M., A. Semalty, Geeta P. Joshi and M.S.M. Rawat, 2010. In vivo hair growth activity of herbal formulations. Int. J. Pharmacol., 6: 53-57.
254. Sharif, A., N. Saim, H. Jasmam and W.Y.W. Ahmad, 2010. Effects of solvent and temperature on the extraction of colorant from onion (Allium cepa) skin using pressurized liquid extraction. Asian J. Applied Sciences, 3: 262-268.
255. Sharma, A., N. Barman and M. Malwal, 2010. Antimicrobial efficacy of nut oil of Semecarpus anacardium: A marking nut tree. Biotechnology, 9: 383-386.
256. Sheela, C.G. and K.T. Augusti, 1992. Antidiabetic effects of S-allyl cysteine sulphoxide isolated from garlic Allium sativum Linn. Indian J. Exp. Biol., 30: 523-526.
257. Shin, D.W., S.N. Kim, S.M. Lee, W. Lee and M.J. Song et al, 2009. (-)-Catechin promotes adipocyte differentiation in human bone marrow mesenchymal stem cells through PPARa transactivation. Biochem. Pharmacol., 77: 125-133.
258. Shokrzadeh, M. and A.G. Ebadi, 2006. Antibacterial effect of garlic (Allium sativum L.) on Staphylococcus aureus. Pak. J. Biol. Sci., 9: 1577-1579.
259. Siddiqui, M.J., Z. Ismail, A.F.A. Aisha and A.M.S. Abdul Majid, 2010. Cytotoxic activity of Catharanthus roseus (Apocynaceae) crude extracts and pure compounds against human colorectal carcinoma cell line. Int. J. Pharmacol, 6: 43-47.
260. Singh, A.B., Akanksha, N. Singh, R. Maurya and A.K. Srivastava, 2009. Anti-hyperglycaemic, lipid lowering and anti-oxidant properties of [6]-gingerol in db/db mice. Int. J. Med. Med. Sci., 1: 536-544.
261. Singh, S., Y.K. Loke and CD. Furberg, 2007. Thiazolidinediones and heart failure: A teleo-analysis. Diabetes Care, 30: 2148-2153.
262. Singh, S., P.K. Sharma, N. Kumar and R. Dudhe, 2010. Biological activities of Aloe vera. Int. J. Pharm. Technol, 211: 259-280.
263. Slimestad, R., T. Fossen and L.M. Vagen, 2007. Onions: A source of unique dietary flavonoids. J. Agric. Food. Chem., 55: 10067-10080.
264. Soleimani, S., F.F. Azarbaizani and V. Nejati, 2007. The effect of Equisetum arvense L. (Equisetaceae) in histological changes of pancreatic [3-cells in streptozotocin-induced diabetic in rats. Pak. J. Biol. Sci., 10: 4236-4240.
265. Sowers, J.R., J. Levy and M.B. Zemel, 1998. Hypertension and diabetes. Med. Clin. North Am., 72: 1399-1414.
266. Srinivasan, K., 2005. Plant foods in the management of diabetes mellitus: Spices as beneficial antidiabetic food adjuncts. Int. J. Food Sci. Nutr., 56: 399-414.
267. Srinivasan, S. and B. Karundevi, 2005. Comparative evaluation of hypoglycaemic activity of two medicinal plants in alloxan diabetic rats. Int. J. Pharmacol, 1: 267-276.
268. Srivastava, Y., H.V. Bhatt, Y. Verma, K. Venkaiah and B.H. Raval, 1993. Antidiabetic and adaptogenic properties of Momordica charantia extract: An experimental and clinical evaluation. Phytother. Res., 7: 285-289.
269. Srividya, N. and S. Periwal, 1995. Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus. Indian J. Exp. Biol, 33: 861-864.
270. Subash-Babu, P. and S. Ignacimuthu, 2007. Antihyperlipidemic and antioxidant effect of hyponidd in the brain of streptozotocin induced diabetic rat. Int. J. Biol. Chem., 1: 196-204.
271. Subhashini, N, G. Nagarajan and S. Kavimani, 2011. Antiinflammatory and in vitro antioxidant property of Trigonella foenum graecum seeds. J. Pharmacol. Toxicol, 6: 371-380.
272. Subramanian, S., D.S. Kumar and P. Arulselvan, 2006a. Wound healing potential of Aloe vera leaf gel studied in experimental rabbits. Asian J. Biochem., 1: 178-185.
273. Subramanian, S., D.S. Kumar, P. Arulselvan and G.P. Senthilkumar, 2006b. In vitro antibacterial and antifungal activities of ethanolic extract of aloe vera leaf gel. J. Plant Sci., 1: 348-355.
274. Subramanian, S., D.S. Kumar, P. Arulselvan, G.P. Senthilkumar and U.S.M. Rao, 2007. Evaluation of anti-ulcerogenic potential of Aloe vera leaf gel extract studied in experimental rats. J. Pharmacol. Toxicol, 2: 85-97.
275. Sukandar, E.Y., H. Permana, I.K. Adnyana, J.I. Sigit, R.A. Ilyas, P. Hasimun and D. Mardiyah, 2010. Clinical study of turmeric (Curcuma longa L.) and garlic (Allium sativum L.) extracts as antihyperglycemic and antihyperlipidemic agent in type-2 diabetes-dyslipidemia patients. Int. J. Pharmacol, 6: 456-463.
276. Sultana, S., F.A. Ripa and K. Hamid, 2010. Comparative antioxidant activity study of some commonly used spices in Bangladesh. Pak. J. Biol. Sci., 13: 340-343.
277. Sunilson, J.A.J., R. Suraj, G. Rejitha, K. Anandarajagopal, A.V.A.G. Kumari and P. Promwichit, 2009. In vitro antimicrobial evaluation of Zingiber officinale, Curcuma longa and Alpinia galangal extracts as natural food preservatives. Am. J. Food Technol, 4: 192-200.
278. Tadera, K., Y. Minami, K. Takamatsu and T. Matsuoka, 2006. Inhibition of a-glucosidase and a-amylase by flavonoids. J. Nutr. Sci. Vitaminol, 52: 149-153.
279. Tagoe, D.N.A., H.D. Nyarko and R. Akpaka, 2011. A comparison of the antifungal properties of onion (Allium cepa), Ginger (Zingiber officinale) and garlic (Allium sativum) against Aspergillus flavus, Aspergillus niger and Cladosporium herbarum. Res. J. Med. Plant, 5: 281-287.
280. Tamayo, C. and S. Diamond, 2007. Review of clinical trials evaluating safety and efficacy of milk thistle (Silybum marianum [L.] Gaertn.). Integr. Cancer Ther., 6: 146-157.
281. Tan, M., J. Ye, N. Turner, C. Hohnen-Behrens and C. Ke et al, 2008. Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway. Chem. Biol, 15: 263-273.
282. Tanaka, H., J. Toyama and R. Akashi, 2009. Molecular characterization of a galactose-binding lectin from Momordica charantia seeds and its expression in tobacco cells. Asian J. Plant Sci., 8: 544-550.
283. Tembhurne, S.V. and D.M. Sakarkar, 2010. Protective effect of Murraya koenigii (L) leaves extract in streptozotocin induced diabetics rats involving possible antioxidant mechanism. J. Med. Plants Res., 410: 2418-2423.
284. Templeton, M. and I. Pieris-Caldwell, 2008. Gestational Diabetes Mellitus in Australia, 2005-06. Australian Institute of Health and Welfare, Canberra, Australia, ISBN-13: 9781740248594, pp: 41.
285. Thirunavukkarasu, P., T. Ramanathan, N. Ravichandran and L. Ramkumar, 2010. Screening of anti-microbial effect in watermelon (Citrullus sp.). J. Biol. Sci., 10: 682-685.
286. Thomson, M., Z.M. Al-Amm, K.K. Al-Qattan, L.H. Shaban and M. Ali, 2007. Anti-diabetic and hypolipidaemic properties of garlic (Allium sativum) in stereptozotocin- induced diabetic rats. Int. J. Diabetes Metabol, 15: 108-115.
287. Tousch, D., A. Lajoix, E. Hosy, J. Azay-Milhau and K. Ferrarex et al, 2008. Chicoric acid, anew compound able to enhance insulin release and glucose uptake. Biochem. Biophys. Res. Commun., 377: 131-135.
288. Ullah, M., F.K. Chy, S.K. Sarkar, M.K. Islam and N. Absar, 2011. Nutrient and phytochemical analysis of four varieties of bitter gourd (Momordica charantia) grown in chittagong hill tracts, Bangladesh. Asian J. Agric. Res., (In Press).
289. Van de Laar, F.A., P.L. Lucassen, R.P. Akkermans, E.H. Van de Lisdonk, G.E. Rutten and C. Van Weel, 2005. Alpha-glucosidase inhibitors for type 2 diabetes mellitus. Cochrane Database Syst. Rev.
290. Vats, V., J.K. Grover and S.S. Rathi, 2002. Evaluation of anti hyperglycemic and hypoglycemic effect of Trigonetta foenum-graecum Linn Ocimum sanctum Linn and Pterocarpus marsupium Linn in normal and alloxanized diabetic rats. J. Ethnopharmacol., 79: 95-100.
291. Vats, V., S.P. Yadav and J.K. Grover, 2004. Ethanolic extract of Ocimum sanctum leaves partially attenuates streptozotocin-induced alterations in glycogen content and carbohydrate metabolism in rats. J. Ethnopharmacol., 90: 155-160.
292. Veena, K, S. Palanivelu and S. Panchanafham, 2006. Protective effect of kalpaamruthaa on altered glycoprotein component levels and membrane stability in mammary carcinoma. Int. J. Cancer Res., 2: 315-329.
293. Veit, M., H. Geiger, V. Wray, A. Abou-Mandour and W. Rozdzinski et al, 1993. Equisetumpyrone, a styrylpyrone glucoside in gametophytes from Equisetum arvense. Phytochemistry, 32: 1029-1032.
294. Vessal, G., M. Akmali, P. Najafi, M.R. Moein and M.M. Sagheb, 2010. Silymarin and milk thistle extract may prevent the progression of diabetic nephropathy in streptozotocin-induced diabetic rats. Renal Failure, 32: 733-739.
295. Vessal, M., M. Hemmati and M. Vasei, 2003. Antidiabetic effects of quercetin in streptozocin-induced diabetic rats. Comp. Biochem. Physiol. C Toxicol. Pharmacol., 135C: 357-364.
296. Vinayagain, A., N. Senthilkumar and A. Umamaheswari, 2008. Larvicidal activity of some medicinal plant extracts against malaria vector Anopheles stephensi. Res. J. Parasitol, 3: 50-58.
297. Vogler, B.K. and E. Enst, 1999. Aloe vera a systematic review of its clinical effectiveness. Br. J. Gen. Practice, 49: 823-828.
298. WHO, 1977. Resolution-promotion and development of training and research in traditional medicine. WHO Document No. WHA 30, pp: 49.
299. Wafsi, I.A., 1994. Some pharmacological studies on Citrullus colocynthis. J. Herbs, Spices Med. Plants, 2: 65-79.
300. Wagensteen, H., B.A. Samuelsen and E.K. Malterude, 2004. Antioxidant activity in extracts from coriander. Food Chem., 88: 293-297.
301. Wang, L., S. Jian, P. Nan, J. Liu and Y. Zhong, 2004. Chemical composition of the essential oil of Elephantopus scaber from southern China. Z. Naturforsch, 59: 327-329.
302. Watanabe, CM., S. Wolffram, P. Ader, G. Rimbach and L. Packer et al, 2001. The in vivo neuromodulatory effects of the herbal medicine ginkgo biloba. Proc. Natl. Acad. Sci. USA., 98: 6577-6580.
303. Wild, S., G. Roglic, A. Green, R. Sicree and H. King, 2004. Global prevalence of diabetes. Diabetes Care, 27: 1047-1053.
304. Winkler, C, B. Wirleitner, K. Schroecksnadel, H. Schennach and D. Fuchs, 2005. Extracts of pumpkin (Cucurbita pepo L.) seeds suppress stimulated peripheral blood mononuclear cells in vitro. Am. J. Immunol., 1: 6-11.
305. Yang, W., H. Wang, J. Shang, F. Feng and N. Xie, 2009. Chemical constituents from Cichorium glandulosum. Chm. J. Nat. Med., 7: 193-195.
306. Ylipaasto, P., K. Klingel, A.M. Lindberg, T. Otonkoski, R. Kandolf, T. Hovi and M. Roivamen, 2004. Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells. Diabetologia, 47: 225-239.
307. Yun, H., J.H. Lee, CE. Park, M. Kim and B. Mm et al, 2009. Inulin increases glucose transport in C2C12 myotubes and HepG2 cells via activation of AMP-activated protein kinase and phosphatidylinositol 3-kinase pathways. J. Med. Food, 12: 1023-1028.