메뉴 건너뛰기




Volumn 12, Issue 3, 2009, Pages 201-212

Neuroprotective evaluation of extract of ginger {zingiber officinale) root in monosodium glutamate-induced toxicity in different brain areas malealbino rats

Author keywords

Brain areas; Ginger; Glutamate; MSG; Neurotoxicity; Rat; Zingiber officinale

Indexed keywords

GLUTAMATE SODIUM; NEUROPROTECTIVE AGENT;

EID: 67049132640     PISSN: 10288880     EISSN: 18125735     Source Type: Journal    
DOI: 10.3923/pjbs.2009.201.212     Document Type: Article
Times cited : (43)

References (70)
  • 1
    • 29944440188 scopus 로고    scopus 로고
    • Mode of action og gingerols and shogaols on 5-HT3 receptors: Binding studies, cation uptake by the receptors channel and contraction of isolated guinea-pig ileum
    • Abdel-Aziz, H., T. Wmdeck, M. Ploch and EJ. Verspohl, 2006. Mode of action og gingerols and shogaols on 5-HT3 receptors: Binding studies, cation uptake by the receptors channel and contraction of isolated guinea-pig ileum. Eur. J. Pharmacol., 530: 136-143.
    • (2006) Eur. J. Pharmacol , vol.530 , pp. 136-143
    • Abdel-Aziz, H.1    Wmdeck, T.2    Ploch, M.3    Verspohl, E.J.4
  • 2
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of nicrosis or apoptosis depending on mitochondrial function
    • Ankarcrona, M., J.M. Dypbukt, E. Bonfoco, B. Zhivotovsky, S. Orremus, S.A. Lipton and P. Nicotera, 1995. Glutamate-induced neuronal death: A succession of nicrosis or apoptosis depending on mitochondrial function. Neuron, 15: 961-973.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orremus, S.5    Lipton, S.A.6    Nicotera, P.7
  • 3
    • 0002565192 scopus 로고    scopus 로고
    • Neurotransmission and the Central Nervous System
    • Hardmann, G.L, L.E. Limbird, P.B. Molinoff, R.W. Ruddon and A.G. Gilman Eds, McGraw-Hill, New York, pp
    • Bloom, F.E., 2001. Neurotransmission and the Central Nervous System. In: The Pharmacological Basis of Therapeutics, 9thEdn, Hardmann, G.L., L.E. Limbird, P.B. Molinoff, R.W. Ruddon and A.G. Gilman (Eds.). McGraw-Hill, New York, pp: 267-290.
    • (2001) The Pharmacological Basis of Therapeutics, 9thEdn , pp. 267-290
    • Bloom, F.E.1
  • 5
    • 23244449899 scopus 로고    scopus 로고
    • Relationship between pituitary and adipose tissue after hypothalamic enervation in the female rat. A morphometric immunohistochemical study
    • Camihort, G., D.C. Gomez, G. Luna, C. Ferese, S. Jurado and G. Moreno et al., 2005. Relationship between pituitary and adipose tissue after hypothalamic enervation in the female rat. A morphometric immunohistochemical study. Cells Tissues Organs, 179: 192-201.
    • (2005) Cells Tissues Organs , vol.179 , pp. 192-201
    • Camihort, G.1    Gomez, D.C.2    Luna, G.3    Ferese, C.4    Jurado, S.5    Moreno, G.6
  • 6
    • 34548549218 scopus 로고    scopus 로고
    • Pro-apoptotic effects of T-acetoxychavicol acetate in human breast carcinoma cells
    • Campbell, C.T., M. Prince, G.M. Landry, V. Kha and H.E. Kleiner, 2007. Pro-apoptotic effects of T-acetoxychavicol acetate in human breast carcinoma cells. Toxicol. Lett, 173: 151-160.
    • (2007) Toxicol. Lett , vol.173 , pp. 151-160
    • Campbell, C.T.1    Prince, M.2    Landry, G.M.3    Kha, V.4    Kleiner, H.E.5
  • 8
    • 33748922627 scopus 로고    scopus 로고
    • Serotonin 5-HT (3) receptors in the central nervous system
    • Chameau, P. and J. A. Van-Hooft, 2006. Serotonin 5-HT (3) receptors in the central nervous system. Cell Tissue Res., 326: 573-581.
    • (2006) Cell Tissue Res , vol.326 , pp. 573-581
    • Chameau, P.1    Van-Hooft, J.A.2
  • 9
    • 8044257439 scopus 로고
    • A sensitive method for spectrofluorometric assay of catecholamines
    • Chang, C.C., 1964. A sensitive method for spectrofluorometric assay of catecholamines. Int. J. Neuropharmacol., 3: 643-649.
    • (1964) Int. J. Neuropharmacol , vol.3 , pp. 643-649
    • Chang, C.C.1
  • 10
    • 0037159574 scopus 로고    scopus 로고
    • Neuronal death and tumor necrosis factor-alpha response to glutamate-induced excitotoxicity in the cerebral cortex of neonatal rats
    • Chaparro-Huerta, V., M.C. Rivera-Cervantes, B.M. Torres-Mendoza and C. Beas-Zarate, 2002. Neuronal death and tumor necrosis factor-alpha response to glutamate-induced excitotoxicity in the cerebral cortex of neonatal rats. Neurosci. Lett, 333: 95-98.
    • (2002) Neurosci. Lett , vol.333 , pp. 95-98
    • Chaparro-Huerta, V.1    Rivera-Cervantes, M.C.2    Torres-Mendoza, B.M.3    Beas-Zarate, C.4
  • 11
    • 0007563490 scopus 로고
    • Further modification of a fluoremetric method for analyzing bram amines
    • Ciarlone, A.E., 1978. Further modification of a fluoremetric method for analyzing bram amines. Microchem. J., 23: 9-12.
    • (1978) Microchem. J , vol.23 , pp. 9-12
    • Ciarlone, A.E.1
  • 12
    • 0023263544 scopus 로고
    • Antifilarial effect of Zingiber officinale on dirofilaria immitis
    • Datta, A. and N.C. Sukul, 1987. Antifilarial effect of Zingiber officinale on dirofilaria immitis. J. Helmmthol, 63: 268-270.
    • (1987) J. Helmmthol , vol.63 , pp. 268-270
    • Datta, A.1    Sukul, N.C.2
  • 13
    • 47749122128 scopus 로고    scopus 로고
    • Modulating effect of ginger extract on rats with ulcerative colitis
    • El-Abhar, H.S., L.N. Hammad and H.S. Gawad, 2008. Modulating effect of ginger extract on rats with ulcerative colitis. J. Ethnopharmacol, 118: 367-372.
    • (2008) J. Ethnopharmacol , vol.118 , pp. 367-372
    • El-Abhar, H.S.1    Hammad, L.N.2    Gawad, H.S.3
  • 14
    • 33744796808 scopus 로고    scopus 로고
    • Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: Modulatory role of vitamin C, vitamin E and quercetin
    • Farmobi, E.O. and O.O. Onyema, 2006. Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: Modulatory role of vitamin C, vitamin E and quercetin. Hum. Exp. Toxicol., 25: 251-259.
    • (2006) Hum. Exp. Toxicol , vol.25 , pp. 251-259
    • Farmobi, E.O.1    Onyema, O.O.2
  • 15
    • 37549064027 scopus 로고    scopus 로고
    • 5-HT receptor regulation of neurotransmitter release
    • Fink, K.B. and M. Gothert, 2007. 5-HT receptor regulation of neurotransmitter release. Pharmacol. Rev., 59: 360-417.
    • (2007) Pharmacol. Rev , vol.59 , pp. 360-417
    • Fink, K.B.1    Gothert, M.2
  • 16
    • 0036707537 scopus 로고    scopus 로고
    • 5-HT3 receptors mediate serotonergic fast synaptic excitation of neocortical vasoactive intestinal peptide cholecystokinin interneurons
    • Ferezou, I., B. Cauli, E.L. Hill, J. Rossier, E. Hamel and B. Lambolez, 2002. 5-HT3 receptors mediate serotonergic fast synaptic excitation of neocortical vasoactive intestinal peptide cholecystokinin interneurons. J. Neurosci., 22: 7389-7397.
    • (2002) J. Neurosci , vol.22 , pp. 7389-7397
    • Ferezou, I.1    Cauli, B.2    Hill, E.L.3    Rossier, J.4    Hamel, E.5    Lambolez, B.6
  • 17
    • 0004039218 scopus 로고
    • 19th Edn, Prentice-Hall International Inc, Connecticut, pp
    • Ganong, W.F., 1990. Review of Medical Physiology. 19th Edn., Prentice-Hall International Inc., Connecticut, pp: 221-243.
    • (1990) Review of Medical Physiology , pp. 221-243
    • Ganong, W.F.1
  • 18
    • 23044503060 scopus 로고    scopus 로고
    • Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways
    • Ghayur, M.N., A.H. Gilani, M.B. Afridi and P. J. Houghton, 2005. Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways. Vascul. Pharmacol., 43: 234-241.
    • (2005) Vascul. Pharmacol , vol.43 , pp. 234-241
    • Ghayur, M.N.1    Gilani, A.H.2    Afridi, M.B.3    Houghton, P.J.4
  • 19
    • 0034023265 scopus 로고    scopus 로고
    • Gill, S.S., R.W. Mueller, P.E. McGuire and O.M. Refined, 2000. Potential target sites in peripheral tissues for excitatory neurotransmission and excitotoxicity. Toxicol. Pathol, 28: 277-285.
    • Gill, S.S., R.W. Mueller, P.E. McGuire and O.M. Refined, 2000. Potential target sites in peripheral tissues for excitatory neurotransmission and excitotoxicity. Toxicol. Pathol, 28: 277-285.
  • 20
    • 0013939811 scopus 로고
    • Regional studies of catecholamines in the rat brain. I. The disposition of [3H] dopamine and [3H] dopa in various regions of the brain
    • Glowmski, J. and L.L. Iversen, 1966. Regional studies of catecholamines in the rat brain. I. The disposition of [3H] dopamine and [3H] dopa in various regions of the brain. J. Neurochem., 13: 655-669.
    • (1966) J. Neurochem , vol.13 , pp. 655-669
    • Glowmski, J.1    Iversen, L.L.2
  • 21
    • 0020448351 scopus 로고
    • Ginger-chemistry, technology and quality evaluation: Part 2
    • Govindarajan, V.S., 1982. Ginger-chemistry, technology and quality evaluation: Part 2. Crit. Rev. Food Sci. Nutr., 17: 189-258.
    • (1982) Crit. Rev. Food Sci. Nutr , vol.17 , pp. 189-258
    • Govindarajan, V.S.1
  • 23
    • 33845262499 scopus 로고    scopus 로고
    • Safety and efficacy of NT an herbal supplement in treating human obesity
    • Greenway, F.L., Z. Liu, C.K. Martin, W. Kai-Yuan and J. Nofziger et al, 2006. Safety and efficacy of NT an herbal supplement in treating human obesity. Int. J. Obes. Lond., 30: 1737-1741.
    • (2006) Int. J. Obes. Lond , vol.30 , pp. 1737-1741
    • Greenway, F.L.1    Liu, Z.2    Martin, C.K.3    Kai-Yuan, W.4    Nofziger, J.5
  • 24
    • 22444431608 scopus 로고    scopus 로고
    • Gmger-an herbal medicinal product with broad anti-inflammatory actions
    • Grzanna, R., L. Lindmark and C.G. Frondoza, 2005. Gmger-an herbal medicinal product with broad anti-inflammatory actions. J. Med. Food., 8: 125-132.
    • (2005) J. Med. Food , vol.8 , pp. 125-132
    • Grzanna, R.1    Lindmark, L.2    Frondoza, C.G.3
  • 25
    • 0035708724 scopus 로고    scopus 로고
    • Reversal of pyrogallol-induced delay in gastric emptying in rats by ginger (Zingiber officinale)
    • Gupta, Y.K. and M. Sharma, 2001. Reversal of pyrogallol-induced delay in gastric emptying in rats by ginger (Zingiber officinale). Methods Find Exp. Clin. Pharmacol, 23: 501-503.
    • (2001) Methods Find Exp. Clin. Pharmacol , vol.23 , pp. 501-503
    • Gupta, Y.K.1    Sharma, M.2
  • 26
    • 0342313461 scopus 로고    scopus 로고
    • Anxiolytic-like effect of combined extracts of Zingiber officinale and Ginkgo biloba in the elevated plus-maze
    • Hasenohrl, R.U., C.H. Nichau, C.H. Frisch and M.A. De-Souza-Silva et al, 1996. Anxiolytic-like effect of combined extracts of Zingiber officinale and Ginkgo biloba in the elevated plus-maze. Pharmacol. Biochem. Behav., 53: 271-275.
    • (1996) Pharmacol. Biochem. Behav , vol.53 , pp. 271-275
    • Hasenohrl, R.U.1    Nichau, C.H.2    Frisch, C.H.3    De-Souza-Silva, M.A.4
  • 27
    • 0026510184 scopus 로고
    • A comparison on the effects of sibutramine hydrochlonde, bupropion and methamphetamine on dopaminergic function evidence that dopamine is not pharmacological target for sibutramine
    • Heal, DJ., A.T. Frankland, J. Gosden, L. Hutchins and M.R. Prow et al, 1992. A comparison on the effects of sibutramine hydrochlonde, bupropion and methamphetamine on dopaminergic function evidence that dopamine is not pharmacological target for sibutramine. Psychopharmacology, 107: 303-309.
    • (1992) Psychopharmacology , vol.107 , pp. 303-309
    • Heal, D.J.1    Frankland, A.T.2    Gosden, J.3    Hutchins, L.4    Prow, M.R.5
  • 28
    • 0020823848 scopus 로고
    • Increase in pituitary dopaminergic receptors after monosodium glutamate treatment
    • Heiman, M.L. and N. Ben-Jonathan, 1983. Increase in pituitary dopaminergic receptors after monosodium glutamate treatment. Am. J. Physiol., 245: E261-E265.
    • (1983) Am. J. Physiol , vol.245
    • Heiman, M.L.1    Ben-Jonathan, N.2
  • 29
    • 35349015960 scopus 로고    scopus 로고
    • A phase II/III randomized, placebo-controlled, double-blind clinical trial of ginger (Zingiber officinale) for nausea caused by chemotherapy for cancer: A currently accruing URCC CCOP cancer control study
    • Hickok, J.T., J.A. Roscoe, G.R. Morrow and J.L. Ryan, 2007. A phase II/III randomized, placebo-controlled, double-blind clinical trial of ginger (Zingiber officinale) for nausea caused by chemotherapy for cancer: A currently accruing URCC CCOP cancer control study. Support Cancer Ther., 4: 247-250.
    • (2007) Support Cancer Ther , vol.4 , pp. 247-250
    • Hickok, J.T.1    Roscoe, J.A.2    Morrow, G.R.3    Ryan, J.L.4
  • 31
    • 41649087229 scopus 로고    scopus 로고
    • Ginger: An ancient remedy and modern miracle drug
    • Hoffman, T., 2007. Ginger: An ancient remedy and modern miracle drug. Hawaii. Med. J., 66: 326-327.
    • (2007) Hawaii. Med. J , vol.66 , pp. 326-327
    • Hoffman, T.1
  • 32
    • 0025670342 scopus 로고
    • The effect of ginger on serotonin induced hypothermia and diarrhea
    • Huang, Q., H. Matsuda, K. Sakai, J. Yamahara and Y. Tamai, 1990. The effect of ginger on serotonin induced hypothermia and diarrhea. Yakugaku Zasshi, 110:936-942.
    • (1990) Yakugaku Zasshi , vol.110 , pp. 936-942
    • Huang, Q.1    Matsuda, H.2    Sakai, K.3    Yamahara, J.4    Tamai, Y.5
  • 33
    • 41349117455 scopus 로고    scopus 로고
    • Comparative effects of dietary ginger (Zingiber officinale) and garlic (Allium sativum) investigated in a type 2 diabetes model of rats
    • Islam, M.S. and H. Choi, 2008. Comparative effects of dietary ginger (Zingiber officinale) and garlic (Allium sativum) investigated in a type 2 diabetes model of rats. J. Med. Food, 11: 152-159.
    • (2008) J. Med. Food , vol.11 , pp. 152-159
    • Islam, M.S.1    Choi, H.2
  • 34
    • 0021675283 scopus 로고
    • Effects of neonatal monosodium glutamate (MSG) treatment on the hormonal and central monoaminergic dynamics associated with acute ether stress in the male rat
    • Johnston, C.A., E.J. Spinedi and A. Negro-Vilar, 1984. Effects of neonatal monosodium glutamate (MSG) treatment on the hormonal and central monoaminergic dynamics associated with acute ether stress in the male rat. Brain Res. Bull., 13: 643-649.
    • (1984) Brain Res. Bull , vol.13 , pp. 643-649
    • Johnston, C.A.1    Spinedi, E.J.2    Negro-Vilar, A.3
  • 35
    • 21144458114 scopus 로고    scopus 로고
    • Zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] prevents 6-hydroxydopamine-induced dopamine depression in mouse striatum and increases superoxide scavenging activity in serum
    • Kabuto, H., M. Nishizawa, M. Tada, C. Higashio, T. Shishibori and M. Kohno, 2005. Zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] prevents 6-hydroxydopamine-induced dopamine depression in mouse striatum and increases superoxide scavenging activity in serum. Neurochem. Res., 30: 325-332.
    • (2005) Neurochem. Res , vol.30 , pp. 325-332
    • Kabuto, H.1    Nishizawa, M.2    Tada, M.3    Higashio, C.4    Shishibori, T.5    Kohno, M.6
  • 36
    • 49349113120 scopus 로고    scopus 로고
    • MSG intake suppresses weight gain, fat deposition and plasma leptin levels in male sprague-dawley rats
    • Kondoh, T. and K. Torn, 2008. MSG intake suppresses weight gain, fat deposition and plasma leptin levels in male sprague-dawley rats. Physiol. Behav., 95: 135-144.
    • (2008) Physiol. Behav , vol.95 , pp. 135-144
    • Kondoh, T.1    Torn, K.2
  • 37
  • 38
    • 23844534499 scopus 로고    scopus 로고
    • Isolation of a natural antioxidant, dehydrozingerone from Zingiber qfficinale and synthesis of its analogues for recognition of effective antioxidant and antityrosinase agents
    • Kuo, RC, A.G. Damu, C.Y. Cherng, J.F. Jeng and CM. Teng, 2005. Isolation of a natural antioxidant, dehydrozingerone from Zingiber qfficinale and synthesis of its analogues for recognition of effective antioxidant and antityrosinase agents. Arch. Pharm. Res., 28: 518-528.
    • (2005) Arch. Pharm. Res , vol.28 , pp. 518-528
    • Kuo, R.C.1    Damu, A.G.2    Cherng, C.Y.3    Jeng, J.F.4    Teng, C.M.5
  • 40
    • 33750591168 scopus 로고    scopus 로고
    • Neuroprotective effect of N-acetylcysteine on neuronal apoptosis induced by a synthetic gingerdione compound: Involvement of ERK and p38 phosphorylation
    • Lin, C.H., S.C Kuo, LJ. Huang and P.W. Gean, 2006. Neuroprotective effect of N-acetylcysteine on neuronal apoptosis induced by a synthetic gingerdione compound: Involvement of ERK and p38 phosphorylation J. Neurosci. Res., 84: 1485-1494.
    • (2006) J. Neurosci. Res , vol.84 , pp. 1485-1494
    • Lin, C.H.1    Kuo, S.C.2    Huang, L.J.3    Gean, P.W.4
  • 42
    • 0022853586 scopus 로고
    • Behavioral and endocrmological effects of single injections of monosodium glutamate in the mouse
    • Lorden, J.F. and A. Caudle, 1986. Behavioral and endocrmological effects of single injections of monosodium glutamate in the mouse. Neurobehav. Toxicol. Teratol., 8: 509-519.
    • (1986) Neurobehav. Toxicol. Teratol , vol.8 , pp. 509-519
    • Lorden, J.F.1    Caudle, A.2
  • 43
    • 35048820000 scopus 로고    scopus 로고
    • Understanding safety of glutamate in food and brain
    • Mallick, H.N., 2007. Understanding safety of glutamate in food and brain. Ind. J. Physiol. Pharmacol, 51: 216-234.
    • (2007) Ind. J. Physiol. Pharmacol , vol.51 , pp. 216-234
    • Mallick, H.N.1
  • 45
    • 17544371065 scopus 로고    scopus 로고
    • Apoptosis and necrosis occur in separate neuronal populations in hippocampus and cerebellum after ischemia and are associated with differential alterations in metabotropic glutamate receptor signaling pathways
    • Martin, LJ., F.E. Sieber and RJ. Traystman, 2000. Apoptosis and necrosis occur in separate neuronal populations in hippocampus and cerebellum after ischemia and are associated with differential alterations in metabotropic glutamate receptor signaling pathways. J. Cereb. Blood Flow. Merab., 20: 153-167.
    • (2000) J. Cereb. Blood Flow. Merab , vol.20 , pp. 153-167
    • Martin, L.J.1    Sieber, F.E.2    Traystman, R.J.3
  • 46
    • 23844455324 scopus 로고    scopus 로고
    • Orexin a stimulates hypothalamic-pituitary-adrenal (HPA) axis function, but not food intake, in the absence of full hypothalamic NPY-ergic activity
    • Moreno, G., M. Perello, RC Gaillard and E. Spinedi, 2005. Orexin a stimulates hypothalamic-pituitary-adrenal (HPA) axis function, but not food intake, in the absence of full hypothalamic NPY-ergic activity. Endocrine, 26: 99-106.
    • (2005) Endocrine , vol.26 , pp. 99-106
    • Moreno, G.1    Perello, M.2    Gaillard, R.C.3    Spinedi, E.4
  • 47
    • 29044438904 scopus 로고    scopus 로고
    • Impact of transient correction of increased adrenocortical activity in hypothalamo-damaged, hyperadipose female rats
    • Moreno, G., M. Perello, G. Camihort, G. Luna, G. Console, RC Gaillard and E. Spinedi, 2006. Impact of transient correction of increased adrenocortical activity in hypothalamo-damaged, hyperadipose female rats. Int. J. Obes. (Lond), 30: 73-82.
    • (2006) Int. J. Obes. (Lond) , vol.30 , pp. 73-82
    • Moreno, G.1    Perello, M.2    Camihort, G.3    Luna, G.4    Console, G.5    Gaillard, R.C.6    Spinedi, E.7
  • 48
    • 0020062345 scopus 로고
    • Motion sickness, ginger and psychophysis
    • Mowrey, D.B. and D.E. Clayson, 1982. Motion sickness, ginger and psychophysis. Lancent, 1: 655-657.
    • (1982) Lancent , vol.1 , pp. 655-657
    • Mowrey, D.B.1    Clayson, D.E.2
  • 49
    • 0034305638 scopus 로고    scopus 로고
    • Effects of chronic administration of sibutramine on body weight, food intake and motor activity in neonatally monosodium glutamate-treated obese female rats: Relationship of antiobesity effect with monoamines
    • Nakagawa, T., K. Ukai, T. Ohyama, Y. Gomita and H. Okamura, 2000. Effects of chronic administration of sibutramine on body weight, food intake and motor activity in neonatally monosodium glutamate-treated obese female rats: Relationship of antiobesity effect with monoamines. Exp. Anim., 49: 239-249.
    • (2000) Exp. Anim , vol.49 , pp. 239-249
    • Nakagawa, T.1    Ukai, K.2    Ohyama, T.3    Gomita, Y.4    Okamura, H.5
  • 50
    • 0021748283 scopus 로고
    • Plasma lipoproteins of monosodium glutamate-induced obese rats
    • Oida, K., T. Nakai, T. Hayashi, S. Miyabo and R. Takeda, 1984. Plasma lipoproteins of monosodium glutamate-induced obese rats. Int. J. Obese., 8: 385-391.
    • (1984) Int. J. Obese , vol.8 , pp. 385-391
    • Oida, K.1    Nakai, T.2    Hayashi, T.3    Miyabo, S.4    Takeda, R.5
  • 51
    • 33748783056 scopus 로고    scopus 로고
    • Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber qfficinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats
    • Ojewole, J.A., 2006. Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber qfficinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats. Phytother. Res., 20: 764-772.
    • (2006) Phytother. Res , vol.20 , pp. 764-772
    • Ojewole, J.A.1
  • 53
    • 17144471622 scopus 로고    scopus 로고
    • Effect of L-glutamate on cholmergic neurotransmission in various brain regions and during the development of rats, when administeredprenatally
    • Ortuno-Sahagun, D., C Beas-Zarate, G. Adame-Gonzalez and A.C. Feria-Velsco, 1997. Effect of L-glutamate on cholmergic neurotransmission in various brain regions and during the development of rats, when administeredprenatally. Neurochem. Int., 31: 683-692.
    • (1997) Neurochem. Int , vol.31 , pp. 683-692
    • Ortuno-Sahagun, D.1    Beas-Zarate, C.2    Adame-Gonzalez, G.3    Feria-Velsco, A.C.4
  • 54
    • 33750102762 scopus 로고    scopus 로고
    • Modulatory effect of monosodium glutamate on rat thymocyte proliferationand apoptosis
    • Pavlovic, V., S. Cekic, D. Sokolovic and B. Djindjic, 2006. Modulatory effect of monosodium glutamate on rat thymocyte proliferationand apoptosis. Bratisl. Lek. Listy., 107: 185-191.
    • (2006) Bratisl. Lek. Listy , vol.107 , pp. 185-191
    • Pavlovic, V.1    Cekic, S.2    Sokolovic, D.3    Djindjic, B.4
  • 56
    • 34250360763 scopus 로고    scopus 로고
    • The effect of the volatile oil from ginger rhizomes (Zingiber qfficinale), its fractions and isolated compounds on the 5-HT3 receptor complex and the serotonmergic system of the rat ileum
    • Riyazi, A., A. Hensel, K. Bauer, N. Geissler, S. Schaaf and EJ. Verspohl, 2007. The effect of the volatile oil from ginger rhizomes (Zingiber qfficinale), its fractions and isolated compounds on the 5-HT3 receptor complex and the serotonmergic system of the rat ileum. Planta Med., 73: 355-362.
    • (2007) Planta Med , vol.73 , pp. 355-362
    • Riyazi, A.1    Hensel, A.2    Bauer, K.3    Geissler, N.4    Schaaf, S.5    Verspohl, E.J.6
  • 57
    • 0026490097 scopus 로고
    • Central effects of monosodium glutamate on feeding behavior in adult Long-Evans rats
    • Stricker-Krongrad, A., B. Beck, J.P. Nicolas and C. Burlet, 1992. Central effects of monosodium glutamate on feeding behavior in adult Long-Evans rats. Pharmacol. Biochem. Behav., 43: 881-886.
    • (1992) Pharmacol. Biochem. Behav , vol.43 , pp. 881-886
    • Stricker-Krongrad, A.1    Beck, B.2    Nicolas, J.P.3    Burlet, C.4
  • 58
    • 0021679209 scopus 로고
    • Pharmacological studies on ginger. I. Pharmacological actions of pungent constituents, (6)-gingerol and (6)-shogaol
    • Suekawa, M., A. Ishige, K. Yuasa, K. Sudo, M. Aburada and E. Hosoya, 1984. Pharmacological studies on ginger. I. Pharmacological actions of pungent constituents, (6)-gingerol and (6)-shogaol. J. Pharmacobiodyn., 7: 836-848.
    • (1984) J. Pharmacobiodyn , vol.7 , pp. 836-848
    • Suekawa, M.1    Ishige, A.2    Yuasa, K.3    Sudo, K.4    Aburada, M.5    Hosoya, E.6
  • 59
    • 0026595848 scopus 로고
    • 5-hydroxytryptamine is a fast excitatory transmitter at 5-HT3 receptors in rat amygdale
    • Sugita, S., K.Z. Shen and R.A. North, 1992. 5-hydroxytryptamine is a fast excitatory transmitter at 5-HT3 receptors in rat amygdale. Neuron, 8: 199-203.
    • (1992) Neuron , vol.8 , pp. 199-203
    • Sugita, S.1    Shen, K.Z.2    North, R.A.3
  • 60
    • 0027185409 scopus 로고    scopus 로고
    • Sun, Y.M., M.L. Ho, H.K. Hsu and M.T. Peng, 1993. The effects of neonatal monosodium glutamate treatment on sex-odor attractively and approach behavior in rats. Geoxig Yi. Xue. Ke. Xue. Za. Zhi., 9: 232-242.
    • Sun, Y.M., M.L. Ho, H.K. Hsu and M.T. Peng, 1993. The effects of neonatal monosodium glutamate treatment on sex-odor attractively and approach behavior in rats. Geoxig Yi. Xue. Ke. Xue. Za. Zhi., 9: 232-242.
  • 62
    • 0027309319 scopus 로고
    • Cholesterol biosynthesis inhibitory component from Zingiber officinale Roscoe
    • Tanabe, M., Y.D. Chen, K. Saito and Y. Kano, 1993. Cholesterol biosynthesis inhibitory component from Zingiber officinale Roscoe. Chem. Pharm. Bull. (Tokyo), 41: 710-713.
    • (1993) Chem. Pharm. Bull. (Tokyo) , vol.41 , pp. 710-713
    • Tanabe, M.1    Chen, Y.D.2    Saito, K.3    Kano, Y.4
  • 63
    • 0036145639 scopus 로고    scopus 로고
    • Enhanced maze performance and reduced oxidative stress by combined extracts of Zingiber ojficinale and ginkgo biloba in the aged rat
    • Topic, B., E. Tarn, K. Tsiakitzis, P.N. Kourounakis, E. Dere and R.U. Hasenöhrl et al, 2002. Enhanced maze performance and reduced oxidative stress by combined extracts of Zingiber ojficinale and ginkgo biloba in the aged rat. Neurobiol. Aging., 23: 135-143.
    • (2002) Neurobiol. Aging , vol.23 , pp. 135-143
    • Topic, B.1    Tarn, E.2    Tsiakitzis, K.3    Kourounakis, P.N.4    Dere, E.5    Hasenöhrl, R.U.6
  • 64
    • 41149093339 scopus 로고    scopus 로고
    • Systemic administration of (6)-gingerol a pungent constituent of ginger, induces hypothermia in rat via an inhibitory effect on metabolic rat
    • Ueki, S., M. Miyoshi, O. Shido, J. Hasegawa and T. Watanabe, 2008. Systemic administration of (6)-gingerol a pungent constituent of ginger, induces hypothermia in rat via an inhibitory effect on metabolic rat. Eur. J. Pharmacol, 584: 87-92.
    • (2008) Eur. J. Pharmacol , vol.584 , pp. 87-92
    • Ueki, S.1    Miyoshi, M.2    Shido, O.3    Hasegawa, J.4    Watanabe, T.5
  • 66
    • 0025000158 scopus 로고
    • Effect of age and monos odium-L-glutamate (MSG) treatment on neurotransmitter content in brain regions from male Fischer-344 rats
    • Wallace, D.R. and R. Jr. Dawson, 1990. Effect of age and monos odium-L-glutamate (MSG) treatment on neurotransmitter content in brain regions from male Fischer-344 rats. Neurochem. Res., 15: 889-898.
    • (1990) Neurochem. Res , vol.15 , pp. 889-898
    • Wallace, D.R.1    Dawson Jr., R.2
  • 67
    • 0032701288 scopus 로고    scopus 로고
    • Modulation noradrenaline concentration in rat frontal cortex and hypothalamus by alpha2-adrenoceptors
    • Wortley, K.E., DJ. Heal and S.C. Stanford, 1999. Modulation noradrenaline concentration in rat frontal cortex and hypothalamus by alpha2-adrenoceptors. Br. J. Pharmacol, 128: 659-666.
    • (1999) Br. J. Pharmacol , vol.128 , pp. 659-666
    • Wortley, K.E.1    Heal, D.J.2    Stanford, S.C.3
  • 68
    • 35448956894 scopus 로고    scopus 로고
    • Effect of an herbal extract Number Ten (NT) on body weight in rats
    • York, D.A., S. Thomas, F.L. Greenway, Z., Liu and J.C. Rood, 2007. Effect of an herbal extract Number Ten (NT) on body weight in rats. Chin. Med., 14:2-10.
    • (2007) Chin. Med , vol.14 , pp. 2-10
    • York, D.A.1    Thomas, S.2    Greenway, F.L.3    Liu, Z.4    Rood, J.C.5
  • 70
    • 67049162679 scopus 로고    scopus 로고
    • Metabolism, 33: 1060-1063
    • Metabolism, 33: 1060-1063.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.