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Volumn 15, Issue 3, 2007, Pages 108-115

Anti-diabetic and hypolipidaemic properties of garlic (Allium sativum) in streptozotocin-induced diabetic rats

Author keywords

Diabetes; Garlic; Hypoglycaemic activity; Hypolipidaemic activity; Proteinuria

Indexed keywords

CHOLESTEROL; GARLIC EXTRACT; GLUCOSE; PROTEIN; STREPTOZOCIN; TRIACYLGLYCEROL;

EID: 63449112936     PISSN: 16067754     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (146)

References (43)
  • 1
    • 0030179028 scopus 로고    scopus 로고
    • Therapeutic values of onion (Allium cepa L.) and garlic (Allium sativum L.)
    • Augusti KT. Therapeutic values of onion (Allium cepa L.) and garlic (Allium sativum L.). Indian J Exp Biol 1996; 34: 634-640
    • (1996) Indian J Exp Biol , vol.34 , pp. 634-640
    • Augusti, K.T.1
  • 2
    • 0025811471 scopus 로고
    • Effect of garlic on thrombocyte aggregation, microcirculation, and other risk factors
    • Kiesewetter H, Jung F, Pindur G, et al. Effect of garlic on thrombocyte aggregation, microcirculation, and other risk factors. Int Clin Pharmacol Ther Toxicol 1991; 29: 151-155.
    • (1991) Int Clin Pharmacol Ther Toxicol , vol.29 , pp. 151-155
    • Kiesewetter, H.1    Jung, F.2    Pindur, G.3
  • 3
    • 0029094911 scopus 로고
    • Consumption of a garlic clove a day could be beneficial in preventing thrombosis
    • Ali M, Thomson M. Consumption of a garlic clove a day could be beneficial in preventing thrombosis. Prostaglandins Leukot Essent Fatty Acids 1995; 53: 211-212.
    • (1995) Prostaglandins Leukot Essent Fatty Acids , vol.53 , pp. 211-212
    • Ali, M.1    Thomson, M.2
  • 6
    • 0033758559 scopus 로고    scopus 로고
    • 2 levels in serum of rabbits receiving a single intravenous dose of aqueous extract of garlic and onion
    • DOI 10.1054/plef.2000.0212
    • Thomson M, Mustafa T, Ali M. Thromboxane-B2 levels in serum of rabbits receiving a single intravenous dose of aqueous extract of garlic and onion. Prostaglandins Leukot Essent Fatty Acids 2000; 63: 217-221. (Pubitemid 30825050)
    • (2000) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.63 , Issue.4 , pp. 217-221
    • Thomson, M.1    Mustafa, T.2    Ali, M.3
  • 7
    • 9044251597 scopus 로고    scopus 로고
    • Antiperoxide effect of S-allyl cysteine sulfoxide, a insulin secretagogue, in diabetic rats
    • Augusti KT, Sheela CG. Antiperoxide effect of S-allyl cysteine sulfoxide, a insulin secretagogue, in diabetic rats. Experientia 1996; 52: 115-120.
    • (1996) Experientia , vol.52 , pp. 115-120
    • Augusti, K.T.1    Sheela, C.G.2
  • 9
    • 18844381076 scopus 로고    scopus 로고
    • Inhibitory effect of garlic extract on oral bacteria
    • DOI 10.1016/j.archoralbio.2004.12.002, PII S0003996905000038
    • Bakri IM, Douglas CW. Inhibitory effect of garlic extract on oral bacteria. Arch Oral Biol 2005; 50: 645-651. (Pubitemid 40689535)
    • (2005) Archives of Oral Biology , vol.50 , Issue.7 , pp. 645-651
    • Bakri, I.M.1    Douglas, C.W.I.2
  • 13
    • 2642540522 scopus 로고    scopus 로고
    • Effect of garlic on cardiovascular disorders: A review
    • Banerjee SK, Maulik SK. Effect of garlic on cardiovascular disorders: a review. Nutr J 2002; 1: 4.
    • (2002) Nutr J , vol.1 , pp. 4
    • Banerjee, S.K.1    Maulik, S.K.2
  • 15
    • 2442423162 scopus 로고    scopus 로고
    • Ajoene (natural garlic compound): A new anti-leukaemia agent for AML therapy
    • Hassan HT: Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy. Leuk Res 2004; 28: 667-671.
    • (2004) Leuk Res , vol.28 , pp. 667-671
    • Hassan, H.T.1
  • 16
    • 0022896896 scopus 로고
    • Antithrombotic organosulfur compounds from garlic: Structural, mechanistic, and synthetic studies
    • DOI 10.1021/ja00282a033
    • Block E, Ahmad S, Catalfamo JL, Jain MK, Apitz-Castro R. Antithrombotic organosulfur compounds from garlic, structural, mechanistic and synthetic studies. J Am Chem Soc 1986; 108: 7045-7055. (Pubitemid 17007930)
    • (1986) Journal of the American Chemical Society , vol.108 , Issue.22 , pp. 7045-7055
    • Block, E.1    Ahmad, S.2    Catalfamo, J.L.3
  • 17
    • 0026773906 scopus 로고
    • Antidiabetic effects of S-allyl cysteine sulphoxide isolated from garlic Allium sativum Linn
    • Sheela CG, Augusti KT. Antidiabetic effects of S-allyl cysteine sulphoxide isolated from garlic Allium sativum Linn. Indian J Exp Biol 1992; 30: 523-526.
    • (1992) Indian J Exp Biol , vol.30 , pp. 523-526
    • Sheela, C.G.1    Augusti, K.T.2
  • 18
    • 0029081239 scopus 로고
    • Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats
    • Sheela CG, Kumud K, Augusti KT. Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats. Planta Med 1995; 61: 356-357.
    • (1995) Planta Med , vol.61 , pp. 356-357
    • Sheela, C.G.1    Kumud, K.2    Augusti, K.T.3
  • 19
    • 70449588115 scopus 로고    scopus 로고
    • Effect of aged garlic extract (AGE) on hyperglycemia induced by immobilization stress in mice
    • Kasuga S, Ushijima M, Morihara N, et al. Effect of aged garlic extract (AGE) on hyperglycemia induced by immobilization stress in mice. Nippon Yakurigaku Zasshi 1999; 1999: 191-197.
    • (1999) Nippon Yakurigaku Zasshi , vol.1999 , pp. 191-197
    • Kasuga, S.1    Ushijima, M.2    Morihara, N.3
  • 20
    • 20444388031 scopus 로고    scopus 로고
    • Effects of garlic oil and diallyl trisulfide on glycemic control in diabetic rats
    • Liu C-T, Hse H, Lii C-K, Chen P-S, Sheen L-Y. Effects of garlic oil and diallyl trisulfide on glycemic control in diabetic rats. Eur J Pharmacol 2005; 516: 165-173.
    • (2005) Eur J Pharmacol , vol.516 , pp. 165-173
    • Liu, C.-T.1    Hse, H.2    Lii, C.-K.3    Chen, P.-S.4    Sheen, L.-Y.5
  • 21
    • 0015700547 scopus 로고
    • Studies on the effect of allicin (diallyl disulphide-oxide) on alloxan diabetes I. Hypoglycaemic action and enhancement of serum insulin effect and glycogen synthesis
    • Mathew PT, Augusti KT. Studies on the effect of allicin (diallyl disulphide-oxide) on alloxan diabetes I. Hypoglycaemic action and enhancement of serum insulin effect and glycogen synthesis. Indian J Biochem Biophys 1973; 10: 209-212.
    • (1973) Indian J Biochem Biophys , vol.10 , pp. 209-212
    • Mathew, P.T.1    Augusti, K.T.2
  • 22
    • 0025073589 scopus 로고
    • Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice
    • Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990; 33: 462-464.
    • (1990) Diabetologia , vol.33 , pp. 462-464
    • Swanston-Flatt, S.K.1    Day, C.2    Bailey, C.J.3    Flatt, P.R.4
  • 23
    • 0345714735 scopus 로고    scopus 로고
    • Endothelium-dependent and -independent effect of aqueous extract of garlic on vascular reactivity on diabetic rats
    • DOI 10.1016/S0367-326X(03)00158-8
    • Baluchnejadmojarad T, Rohgani M. Endothelium-dependent and -independent effect of aqueous extract of garlic on vascular reactivity on diabetic rats. Filoterapia 2003; 74: 630-637. (Pubitemid 37443450)
    • (2003) Fitoterapia , vol.74 , Issue.7-8 , pp. 630-637
    • Baluchnejadmojarad, T.1    Roghani, M.2
  • 24
    • 0041570188 scopus 로고    scopus 로고
    • Garlic extract attenuates time-dependent changes in the reactivity of isolated aorta in streptozotocin-diabetic rats
    • DOI 10.1016/S0024-3205(03)00604-0
    • Baluchnejadmojarad T, Rohgani M. Garlic extract attenuates time-dependent changes in the reactivity of isolated aorta in streptozotocin-diabetic rats. Life Sci 2003; 73: 2281-2289. (Pubitemid 36980825)
    • (2003) Life Sciences , vol.73 , Issue.18 , pp. 2281-2289
    • Baluchnejadmojarad, T.1    Roghani, M.2
  • 25
    • 0035122927 scopus 로고    scopus 로고
    • A commentary on the effects of garlic extraction and formulation on product composition
    • Staba EJ, Lash L, Staba JE. A commentary on the effects of garlic extraction and formulation on product composition. J Nutr 2001; 131: 1118S-1119S. (Pubitemid 32195020)
    • (2001) Journal of Nutrition , vol.131 , Issue.3 SUPPL.
    • Staba, E.J.1    Lash, L.2    Staba, J.E.3
  • 26
    • 0029943883 scopus 로고    scopus 로고
    • Histopathological effects of garlic on liver and lung of rats
    • DOI 10.1016/0378-4274(96)03658-2
    • Alnaqeeb M, Thomson M, Bordia T, Ali M. Histopathological effects of garlic on liver and lung of rats. Toxicol Lett 1996; 85: 157-164. (Pubitemid 26164335)
    • (1996) Toxicology Letters , vol.85 , Issue.3 , pp. 157-164
    • Alnaqeeb, M.A.1    Thomson, M.2    Bordia, T.3    Ali, M.4
  • 27
    • 0032985666 scopus 로고    scopus 로고
    • The antihypertensive effect of garlic (Allium sativum) in the rat two- Kidney-one-clip Goldblatt model
    • DOI 10.1016/S0378-8741(98)00173-1, PII S0378874198001731
    • Al-Qattan KK, Alnaqeeb MA, Ali M. The antihypertensive effect of garlic (Allium sativum) in the rat two kidney-one clip Goldblatt model. J Ethnopharmacol 1999; 66: 217-222. (Pubitemid 29307923)
    • (1999) Journal of Ethnopharmacology , vol.66 , Issue.2 , pp. 217-222
    • Al-Qattan, K.K.1    Alnaqeeb, M.A.2    Ali, M.3
  • 28
    • 0344873741 scopus 로고    scopus 로고
    • Mechanism of garlic (Allium sativum) induced reduction of hypertension in 2K-1C rats. a possible mediation of Na/H exchanger isoform-1
    • Al-Qattan KK, Khan I, Alnaqeeb MA, Ali M. Mechanism of garlic (Allium sativum) induced reduction of hypertension in 2K-1C rats. A possible mediation of Na/H exchanger isoform-1. Prostaglandins Leukot Essent Fatty Acids 2003; 69: 217-222.
    • (2003) Prostaglandins Leukot Essent Fatty Acids , vol.69 , pp. 217-222
    • Al-Qattan, K.K.1    Khan, I.2    Alnaqeeb, M.A.3    Ali, M.4
  • 29
    • 0026531943 scopus 로고
    • Changes in tyrosine phosphorylation of insulin receptors and a 170,000 molecular weight non-receptor protein in vivo in skeletal muscle in streptozotocin-induced diabetic rats: Effects of insulin and glucose
    • Giorgino F, Chen JH, Smith RJ. Changes in tyrosine phosphorylation of insulin receptors and a 170,000 molecular weight non-receptor protein in vivo in skeletal muscle in streptozotocin-induced diabetic rats: effects of insulin and glucose. Endocrinology 1992; 130: 1433-1444.
    • (1992) Endocrinology , vol.130 , pp. 1433-1444
    • Giorgino, F.1    Chen, J.H.2    Smith, R.J.3
  • 30
    • 0348023269 scopus 로고    scopus 로고
    • Veterinary Medical Care (Chapter 3)
    • Washington DC: Institute for Laboratory Animal Research, American Academy of Sciences
    • Veterinary Medical Care (Chapter 3). In: Guide for the Care and Use of Laboratory Animals. Washington DC: Institute for Laboratory Animal Research, American Academy of Sciences, 1996.
    • (1996) Guide for the Care and Use of Laboratory Animals
  • 31
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 32
    • 0242284429 scopus 로고    scopus 로고
    • Second Edition. Belgium: International Diabetes Federation (IDF)
    • Diabetes Atlas, Second Edition. Belgium: International Diabetes Federation (IDF), 2003.
    • (2003) Diabetes Atlas
  • 33
    • 0242380324 scopus 로고    scopus 로고
    • Diabetes, microvascular complications, and cardiovascular complications: What is it about glucose?
    • Reusch JE. Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose? J Clin Invest 2003; 112: 986-988.
    • (2003) J Clin Invest , vol.112 , pp. 986-988
    • Reusch, J.E.1
  • 35
    • 0004121625 scopus 로고    scopus 로고
    • 5th Edition. Edinburgh: Churchill Livingstone, Elsevier Science Ltd
    • Rang HP, Dale MM, Ritter JM, Moore PK. Pharmacology, 5th Edition. Edinburgh: Churchill Livingstone, Elsevier Science Ltd., 2003: 387-392.
    • (2003) Pharmacology , pp. 387-392
    • Rang, H.P.1    Dale, M.M.2    Ritter, J.M.3    Moore, P.K.4
  • 37
    • 0037244018 scopus 로고    scopus 로고
    • Enumerating autoreactive T cells in peripheral blood: A big step in diabetes prediction
    • Eisenbarth GS, Kotzin BL. Enumerating autoreactive T cells in peripheral blood: a big step in diabetes prediction. J Clin Invest 2003; 111: 179-181.
    • (2003) J Clin Invest , vol.111 , pp. 179-181
    • Eisenbarth, G.S.1    Kotzin, B.L.2
  • 38
    • 22144446730 scopus 로고    scopus 로고
    • Effect of fenugreek, onion and garlic on blood glucose and histopathology of pancreas of alloxan-induced diabetic rats
    • Jelodar GA, Maleki M, Motadayen MH, Sirus S. Effect of fenugreek, onion and garlic on blood glucose and histopathology of pancreas of alloxan-induced diabetic rats. Indian J Med Sci 2005; 59: 64-69. (Pubitemid 40975979)
    • (2005) Indian Journal of Medical Sciences , vol.59 , Issue.2 , pp. 64-69
    • Jelodar, G.A.1    Maleki, M.2    Motadayen, M.H.3    Sirus, S.4
  • 39
    • 0032911972 scopus 로고    scopus 로고
    • Proteinuria, albuminuria, risk, assessment, detection, elimination (PARADE): A position paper of the National Kidney Foundation
    • Keane WF, Eknoyan G. Proteinuria, albuminuria, risk, assessment, detection, elimination (PARADE): A position paper of the national kidney foundation. Am J Kidney Dis 1999; 33: 1004-1010. (Pubitemid 29214705)
    • (1999) American Journal of Kidney Diseases , vol.33 , Issue.5 , pp. 1004-1010
    • Keane, W.F.1    Eknoyan, G.2    Willis, K.3
  • 41
    • 0018745544 scopus 로고
    • Prevention of diabetic glomerulopathy in streptozotocin diabetic rats by insulin treatment. Kidney size and glomerular volume
    • Rasch R. Prevention of diabetic glomerulopathy in streptozotocin diabetic rats by insulin treatment. Kidney size and glomerular volume. Diabetologia 1979; 16: 124-128.
    • (1979) Diabetologia , vol.16 , pp. 124-128
    • Rasch, R.1
  • 42
    • 9644289401 scopus 로고    scopus 로고
    • Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats
    • DOI 10.1016/j.fct.2004.08.012, PII S0278691504002741
    • El-Demerdash FM, Yousef MI, El-Naga NI. Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats. Food Chem Toxicol 2005; 43: 57-63. (Pubitemid 39575733)
    • (2005) Food and Chemical Toxicology , vol.43 , Issue.1 , pp. 57-63
    • El-Demerdash, F.M.1    Yousef, M.I.2    El-Naga, N.I.A.3
  • 43
    • 0016808244 scopus 로고
    • Hypoglycemic action of onion and garlic
    • Jain RC, Vyas CR. Hypoglycemic action of onion and garlic. Am J Clin Nutr 1975; 28: 684-685.
    • (1975) Am J Clin Nutr , vol.28 , pp. 684-685
    • Jain, R.C.1    Vyas, C.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.