Momordica charantia constituents and antidiabetic screening of the isolated major compounds

Chemical and Pharmaceutical Bulletin

Volumn 54, Issue 7, 2006, Pages 1017-1021

  Harinantenaina, Liva ^a   Tanaka, Michi ^a   Takaoka, Shigeru ^a   Oda, Munehiro ^b   Mogami, Orie ^b   Uchida, Masayuki ^b   Asakawa, Yoshinori ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b MEIJI DAIRIES CORPORATION   (Japan)

Author keywords

Antidiabetic, ddY mice; Cucurbitaceae; Cucurbitane; Momordica charantia

Indexed keywords

3BETA 7BETA 25 TRIHYDROXYCUCURBITA 5,23 DIEN 9 AL; 5BETA 19 EPOXY 3BETA 25 DIHYDROXYCUCURBITA 6 23 DIENE; MOMORDICA CHARANTIA EXTRACT; TRITERPENOID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DRUG ACTIVITY; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; FRACTIONATION; MOMORDICA CHARANTIA; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; X RAY CRYSTALLOGRAPHY;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS; DRUG EVALUATION, PRECLINICAL; HYPOGLYCEMIC AGENTS; MALE; MICE; MOLECULAR STRUCTURE; MOMORDICA CHARANTIA; TRITERPENES;

EID: 33745685683     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.54.1017     Document Type: Article

References (16)

1. Zimmet P. Z., Diabetes Care, 15, 232-252 (1992).
2. Amos A., McCarty D., Zimmet P. Z., Diabetic Medicine, 14, S1-S85 (1997).
3. King H., Aubert R., Herman W., Diabetes Care, 21, 1414-1431 (1998).
4. Okabe H., Miyahara Y., Yamauchi T., Miyahara K., Chem. Pharm. Bull., 28, 2753-2762 (1980).
5. Okabe H., Miyahara Y., Yamauchi. T., Chem. Pharm. Bull., 30, 4334-4340 (1982).
6. Okabe H., Miyahara Y., Yamauchi T., Tetrahedron Lett., 23, 77-80 (1982).
7. Miyahara Y., Okabe H., Yamauchi T., Chem. Pharm. Bull., 29, 1561-1566 (1981).
8. Yasuda M., Iwamoto M., Okabe H., Yamauchi T., Chem. Pharm. Bull., 32, 2044-2047 (1984).
9. Murakami T., Emoto A., Matsuda H., Yoshikawa M., Chem. Pharm. Bull., 49, 54-63 (2001).
10. Begum S., Ahmed M., Siddiqui B. S., Khan A., Saify Z. S., Arif M., Phytochemistry, 44, 1313-1320 (1997).
11. Fatope M. O., Takeda Y., Yamashita. H., Okabe H., Yamauchi T., J. Nat. Prod., 53, 1491-1497 (1990).
12. Raman A., Lau C., Phytomedicine, 2, 349-362 (1996).
13. Grover J. K., Ydav S. P., J. Ethnopharm., 93, 123-132 (2004) and references cited herein.
14. Mulholland D. A., Sewram V., Osborne R., Pegel K. H., Connolly J. D., Phytochemistry, 45, 391-395 (1997).
15. Mackay S., Gilmore C. J., Edwards C., Stewart N., Shankland K., Bruker Nonius, MacSciences, The Netherlands, Japan & The University of Glasgow, 1999.
16. Sheldrick G. M., SHELXL97. Program for the rafinement of crystal structures. University of Gottingen, Germany, 1997.