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Volumn 32, Issue 6, 2010, Pages 733-739

Silymarin and milk thistle extract may prevent the progression of diabetic nephropathy in streptozotocin-induced diabetic rats

Author keywords

Antioxidants; Diabetic nephropathy; Milk thistle extract; Rat; Silymarin

Indexed keywords

CATALASE; CREATININE; GLUCOSE; GLUTATHIONE PEROXIDASE; PROTEIN; SILYBUM MARIANUM EXTRACT; SILYMARIN; STREPTOZOCIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UREA;

EID: 77953570914     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/0886022X.2010.486488     Document Type: Article
Times cited : (55)

References (40)
  • 1
    • 14644395554 scopus 로고    scopus 로고
    • Renal damage in patients with Type 2 diabetes: A strong predictor of mortality
    • Bo S, Ciccone G, Rosato R, et al. Renal damage in patients with Type 2 diabetes: A strong predictor of mortality. Diabet Med. 2005;22(3):258-265.
    • (2005) Diabet Med , vol.22 , Issue.3 , pp. 258-265
    • Bo, S.1    Ciccone, G.2    Rosato, R.3
  • 2
    • 19844372962 scopus 로고    scopus 로고
    • Type 2 diabetic nephropathy: Clinical course and prevention proposals, 2004
    • Tarchini R, Bottini E, Botti P, et al. Type 2 diabetic nephropathy: clinical course and prevention proposals 2004. G Ital Nefrol. 2005;22 (Suppl 31):S15-19.
    • (2005) G Ital Nefrol. , vol.22 , Issue.SUPPL. 31
    • Tarchini, R.1    Bottini, E.2    Botti, P.3
  • 3
    • 0344393682 scopus 로고    scopus 로고
    • Microalbuminuria and clinical proteinuria as the main predictive factors of cardiovascular morbidity and mortality in patients with type 2 diabetes
    • Gimeno Orna JA, Boned Juliani B, Lou Arnal LM, Castro Alonso FJ. Microalbuminuria and clinical proteinuria as the main predictive factors of cardiovascular morbidity and mortality in patients with type 2 diabetes. Rev Clin Esp. 2003;203(11): 526-531.
    • (2003) Rev Clin Esp , vol.203 , Issue.11 , pp. 526-531
    • Gimeno Orna, J.A.1    Boned Juliani, B.2    Lou Arnal, L.M.3    Castro Alonso, F.J.4
  • 4
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes JW. Role of oxidative stress in development of complications in diabetes. Diabetes. 1991;40(4):405-412.
    • (1991) Diabetes , vol.40 , Issue.4 , pp. 405-412
    • Baynes, J.W.1
  • 5
    • 0029166623 scopus 로고
    • Role of oxidative stress in the development of diabetic nephropathy
    • Ha H, Kim KH. Role of oxidative stress in the development of diabetic nephropathy. Kidney Int Suppl. 1995;51:S18-21.
    • (1995) Kidney Int Suppl , vol.51
    • Ha, H.1    Kim, K.H.2
  • 6
    • 0027385062 scopus 로고
    • Daily vitamin e supplements improve metabolic control but not insulin secretion in elderly type II diabetic patients
    • Paolisso G, D'Amore A, Galzerano D, et al. Daily vitamin E supplements improve metabolic control but not insulin secretion in elderly type II diabetic patients. Diabetes Care. 1993; 16(11):1433-1437.
    • (1993) Diabetes Care , vol.16 , Issue.11 , pp. 1433-1437
    • Paolisso, G.1    D'Amore, A.2    Galzerano, D.3
  • 7
    • 0032954074 scopus 로고    scopus 로고
    • Lipid peroxidation and antioxidant enzyme activities in patients with type 1 diabetes mellitus
    • Ruiz C, Alegria A, Barbera R, Farre R, Lagarda MJ. Lipid peroxidation and antioxidant enzyme activities in patients with type 1 diabetes mellitus. Scand J Clin Lab Invest. 1999;59(2): 99-105.
    • (1999) Scand J Clin Lab Invest , vol.59 , Issue.2 , pp. 99-105
    • Ruiz, C.1    Alegria, A.2    Barbera, R.3    Farre, R.4    Lagarda, M.J.5
  • 8
    • 0031044075 scopus 로고    scopus 로고
    • Enalaprilat inhibits hydrogen peroxide production by murine mesangial cells exposed to high glucose concentrations
    • Ruiz-Munoz LM, Vidal-Vanaclocha F, Lampreabe I. Enalaprilat inhibits hydrogen peroxide production by murine mesangial cells exposed to high glucose concentrations. Nephrol Dial Transplant. 1997;12(3):456-464.
    • (1997) Nephrol Dial Transplant , vol.12 , Issue.3 , pp. 456-464
    • Ruiz-Munoz, L.M.1    Vidal-Vanaclocha, F.2    Lampreabe, I.3
  • 10
    • 0032029363 scopus 로고    scopus 로고
    • AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept
    • Bierhaus A, Hofmann MA, Ziegler R, Nawroth PP. AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept. Cardiovasc Res. 1998; 37(3):586-600.
    • (1998) Cardiovasc Res , vol.37 , Issue.3 , pp. 586-600
    • Bierhaus, A.1    Hofmann, M.A.2    Ziegler, R.3    Nawroth, P.P.4
  • 11
    • 0028908348 scopus 로고
    • Advanced protein glycosylation in diabetes and aging
    • Brownlee M. Advanced protein glycosylation in diabetes and aging. Annu Rev Med. 1995;46:223-234.
    • (1995) Annu Rev Med , vol.46 , pp. 223-234
    • Brownlee, M.1
  • 12
    • 33846519345 scopus 로고    scopus 로고
    • Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine
    • Pradhan SC, Girish C. Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine. Indian J Med Res. 2006;124(5):491-504.
    • (2006) Indian J Med Res , vol.124 , Issue.5 , pp. 491-504
    • Pradhan, S.C.1    Girish, C.2
  • 13
    • 34248216953 scopus 로고    scopus 로고
    • Rodent models of streptozotocin-induced diabetic nephropathy
    • Tesch GH, Allen TJ. Rodent models of streptozotocin-induced diabetic nephropathy. Nephrology (Carlton) 2007;12(3):261-266.
    • (2007) Nephrology (Carlton , vol.12 , Issue.3 , pp. 261-266
    • Tesch, G.H.1    Allen, T.J.2
  • 14
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 15
    • 0002272382 scopus 로고    scopus 로고
    • Renal function and nitrogen metabolites
    • Burits CA, Ashwood ER, eds. 3rd ed., Philadelphia: WB Saunders
    • Newman D, Price C. Renal function and nitrogen metabolites. In: Burits CA, Ashwood ER, eds. Tietz Textbook of Clinical Chemistry. 3rd ed., Philadelphia: WB Saunders;1999.
    • (1999) Tietz Textbook of Clinical Chemistry
    • Newman, D.1    Price, C.2
  • 16
    • 34347355327 scopus 로고    scopus 로고
    • Comparison of the effects of vitamin e and/or quercetin in attenuating chronic cyclosporine A-induced nephrotoxicity in male rats
    • Zal F, Mostafavi-Pour Z, Vessal M. Comparison of the effects of vitamin E and/or quercetin in attenuating chronic cyclosporine A-induced nephrotoxicity in male rats. Clin Exp Pharmacol Physiol. 2007;34(8):720-724.
    • (2007) Clin Exp Pharmacol Physiol , vol.34 , Issue.8 , pp. 720-724
    • Zal, F.1    Mostafavi-Pour, Z.2    Vessal, M.3
  • 17
    • 33645078395 scopus 로고    scopus 로고
    • Taurine attenuates hypertension and renal dysfunction induced by cyclosporine A in rats
    • Hagar HH, El Etter E, Arafa M. Taurine attenuates hypertension and renal dysfunction induced by cyclosporine A in rats. Clin Exp Pharmacol Physiol. 2006;33(3):189-196.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , Issue.3 , pp. 189-196
    • Hagar, H.H.1    El Etter, E.2    Arafa, M.3
  • 18
    • 0020662088 scopus 로고
    • Superoxide dismutase, catalase and glutathione peroxidase in the human cataractous lens
    • Fecondo JV, Augusteyn RC. Superoxide dismutase, catalase and glutathione peroxidase in the human cataractous lens. Exp Eye Res. 1983;36(1):15-23.
    • (1983) Exp Eye Res , vol.36 , Issue.1 , pp. 15-23
    • Fecondo, J.V.1    Augusteyn, R.C.2
  • 19
    • 0000024076 scopus 로고
    • Catalase
    • Bergmeyer HU, ed. 3rd ed., Weinheim: Verlag Chemie
    • Aebi H. Catalase. In: Bergmeyer HU, ed. Methods of enzymatic analysis. 3rd ed., Weinheim: Verlag Chemie; 1983:273-286.
    • (1983) Methods of Enzymatic Analysis , pp. 273-286
    • Aebi, H.1
  • 20
    • 0015523099 scopus 로고
    • The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase
    • Misra HP, Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem. 1972;247(10):3170-3175.
    • (1972) J Biol Chem , vol.247 , Issue.10 , pp. 3170-3175
    • Misra, H.P.1    Fridovich, I.2
  • 21
    • 0023555979 scopus 로고
    • Radical scavenging by flavonoid antioxidants
    • Bors W, Saran M. Radical scavenging by flavonoid antioxidants. Free Radic Res Commun. 1987;2(4-6):289-294.
    • (1987) Free Radic Res Commun , vol.2 , Issue.4-6 , pp. 289-294
    • Bors, W.1    Saran, M.2
  • 22
    • 0025004502 scopus 로고
    • Flavonoids as antioxidants: Determination of radical-scavenging efficiencies
    • Bors W, Heller W, Michel C, Saran M. Flavonoids as antioxidants: determination of radical-scavenging efficiencies. Methods Enzymol. 1990;186:343-355.
    • (1990) Methods Enzymol , vol.186 , pp. 343-355
    • Bors, W.1    Heller, W.2    Michel, C.3    Saran, M.4
  • 25
    • 0033764060 scopus 로고    scopus 로고
    • Alpha-lipoic acid: A multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes
    • Evans JL, Goldfine ID. Alpha-lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes. Diabetes Technol Ther. 2000; 2(3):401-413.
    • (2000) Diabetes Technol Ther , vol.2 , Issue.3 , pp. 401-413
    • Evans, J.L.1    Goldfine, I.D.2
  • 26
    • 0035140346 scopus 로고    scopus 로고
    • Protection against oxidative stressinduced insulin resistance in rat L6 muscle cells by mircomolar concentrations of alpha-lipoic acid
    • Maddux BA, See W, Lawrence JC, Jr., Goldfine AL, Goldfine ID, Evans JL. Protection against oxidative stressinduced insulin resistance in rat L6 muscle cells by mircomolar concentrations of alpha-lipoic acid. Diabetes. 2001;50(2):404-410.
    • (2001) Diabetes , vol.50 , Issue.2 , pp. 404-410
    • Maddux, B.A.1    See, W.2    Lawrence Jr., J.C.3    Goldfine, A.L.4    Goldfine, I.D.5    Evans, J.L.6
  • 27
    • 1942473768 scopus 로고    scopus 로고
    • Quercetin, an anti-oxidant bioflavonoid, attenuates diabetic nephropathy in rats
    • DOI 10.1111/j.1440-1681.2004.03982.x
    • Anjaneyulu M, Chopra K. Quercetin, an anti-oxidant bioflavonoid, attenuates diabetic nephropathy in rats. Clin Exp Pharmacol Physiol. 2004;31(4):244-248. (Pubitemid 38507865)
    • (2004) Clinical and Experimental Pharmacology and Physiology , vol.31 , Issue.4 , pp. 244-248
    • Anjaneyulu, M.1    Chopra, K.2
  • 28
    • 0020455417 scopus 로고
    • Functional beta cell regeneration in the islets of pancreas in alloxan induced diabetic rats by (-)-epicatechin
    • Chakravarthy BK, Gupta S, Gode KD. Functional beta cell regeneration in the islets of pancreas in alloxan induced diabetic rats by (-)-epicatechin. Life Sci. 1982;31(24):2693-2697.
    • (1982) Life Sci , vol.31 , Issue.24 , pp. 2693-2697
    • Chakravarthy, B.K.1    Gupta, S.2    Gode, K.D.3
  • 29
    • 0020628943 scopus 로고
    • The lack of effectiveness of (-)-epicatechin against alloxan induced diabetes in Wistar rats
    • Sheehan EW, Stiff DD, Duah F, Slatkin DJ, Schiff PL, Jr., Zemaitis MA. The lack of effectiveness of (-)-epicatechin against alloxan induced diabetes in Wistar rats. Life Sci. 1983; 33(7):593-597.
    • (1983) Life Sci , vol.33 , Issue.7 , pp. 593-597
    • Sheehan, E.W.1    Stiff, D.D.2    Duah, F.3    Slatkin, D.J.4    Schiff Jr., P.L.5    Zemaitis, M.A.6
  • 30
    • 0021986103 scopus 로고
    • Assessment of the antidiabetic activity of epicatechin in streptozotocindiabetic and spontaneously diabetic BB/E rats
    • Bone AJ, Hii CS, Brown D, Smith W, Howell SL. Assessment of the antidiabetic activity of epicatechin in streptozotocindiabetic and spontaneously diabetic BB/E rats. Biosci Rep. 1985;5(3):215-221.
    • (1985) Biosci Rep , vol.5 , Issue.3 , pp. 215-221
    • Bone, A.J.1    Hii, C.S.2    Brown, D.3    Smith, W.4    Howell, S.L.5
  • 31
    • 0027074281 scopus 로고
    • The efficacy of quercetin in alloxan diabetes
    • Nuraliev Iu N, Avezov GA. The efficacy of quercetin in alloxan diabetes. Eksp Klin Farmakol. 1992;55(1):42-44.
    • (1992) Eksp Klin Farmakol , vol.55 , Issue.1 , pp. 42-44
    • Nuraliev Iu, N.1    Avezov, G.A.2
  • 32
    • 0041589462 scopus 로고    scopus 로고
    • Antidiabetic effects of quercetin in streptozotocin-induced diabetic rats
    • Vessal M, Hemmati M, Vasei M. Antidiabetic effects of quercetin in streptozotocin-induced diabetic rats. Comp Biochem Physiol C Toxicol Pharmacol. 2003;135C(3):357-364.
    • (2003) Comp Biochem Physiol C Toxicol Pharmacol , vol.135 C , Issue.3 , pp. 357-364
    • Vessal, M.1    Hemmati, M.2    Vasei, M.3
  • 33
    • 2342419096 scopus 로고    scopus 로고
    • Study of the hypoglycaemic activity of Fraxinus excelsior and Silybum marianum in an animal model of type 1 diabetes mellitus
    • Maghrani M, Zeggwagh NA, Lemhadri A, El Amraoui M, Michel JB, Eddouks M. Study of the hypoglycaemic activity of Fraxinus excelsior and Silybum marianum in an animal model of type 1 diabetes mellitus. J Ethnopharmacol. 2004;91(2-3): 309-316.
    • (2004) J Ethnopharmacol , vol.91 , Issue.2-3 , pp. 309-316
    • Maghrani, M.1    Zeggwagh, N.A.2    Lemhadri, A.3    El Amraoui, M.4    Michel, J.B.5    Eddouks, M.6
  • 34
    • 36348975777 scopus 로고    scopus 로고
    • Effects of silymarin (hepatoprotector) and succinic acid (bioenergy regulator) on metabolic disorders in experimental diabetes mellitus
    • Vengerovskii AI, Khazanov VA, Eskina KA, Vasilyev KY. Effects of silymarin (hepatoprotector) and succinic acid (bioenergy regulator) on metabolic disorders in experimental diabetes mellitus. Bull Exp Biol Med. 2007;144(1):53-56.
    • (2007) Bull Exp Biol Med , vol.144 , Issue.1 , pp. 53-56
    • Vengerovskii, A.I.1    Khazanov, V.A.2    Eskina, K.A.3    Vasilyev, K.Y.4
  • 36
    • 77953571775 scopus 로고    scopus 로고
    • Mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats
    • in press
    • Li X, Cui X, Sun X, Li X, Zhu Q, Li W. Mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats. Phytother Res. 2009;(in press).
    • (2009) Phytother Res
    • Li, X.1    Cui, X.2    Sun, X.3    Li, X.4    Zhu, Q.5    Li, W.6
  • 37
    • 40149098047 scopus 로고    scopus 로고
    • Renoprotection by telmisartan versus benazepril in streptozotocin induced diabetic nephropathy
    • Singh J, Budhiraja S, Lal H, Arora R. Renoprotection by telmisartan versus benazepril in streptozotocin induced diabetic nephropathy. Iran J Pharmacol Thera. 2006;5(2): 135-139.
    • (2006) Iran J Pharmacol Thera , vol.5 , Issue.2 , pp. 135-139
    • Singh, J.1    Budhiraja, S.2    Lal, H.3    Arora, R.4
  • 38
    • 40049092280 scopus 로고    scopus 로고
    • Protective effects of a combination of quercetin and vitamin e against cyclosporine A-induced oxidative stress and hepatotoxicity in rats
    • Mostafavi-Pour Z, Zal F, Monabati A, Vessal M. Protective effects of a combination of quercetin and vitamin E against cyclosporine A-induced oxidative stress and hepatotoxicity in rats. Hepatol Res. 2008;38(4):385-392.
    • (2008) Hepatol Res , vol.38 , Issue.4 , pp. 385-392
    • Mostafavi-Pour, Z.1    Zal, F.2    Monabati, A.3    Vessal, M.4
  • 40
    • 0027992226 scopus 로고
    • Scavenging of reactive oxygen species by silibinin dihemisuccinate
    • Mira L, Silva M, Manso CF. Scavenging of reactive oxygen species by silibinin dihemisuccinate. Biochem Pharmacol. 1994; 48(4):753-759.
    • (1994) Biochem Pharmacol , vol.48 , Issue.4 , pp. 753-759
    • Mira, L.1    Silva, M.2    Manso, C.F.3


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