메뉴 건너뛰기




Volumn 96, Issue 4, 2006, Pages 660-666

Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats

Author keywords

Anti diabetic properties; Diabetes; Ginger; Hypoglycaemic properties; Hypolipidaemic properties; Proteinuria

Indexed keywords

CHOLESTEROL; GINGER EXTRACT; GLUCOSE; STREPTOZOCIN; TRIACYLGLYCEROL; ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; PLANT EXTRACT;

EID: 33947274715     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1079/BJN20061849     Document Type: Article
Times cited : (327)

References (48)
  • 1
    • 23644434954 scopus 로고    scopus 로고
    • 5-HT3 receptor blocking activity of arhyalkanes isolated from the rhizome of Zingiber officinale
    • Abdel-Aziz H, Nahrstedt A, Peterelt F, Windeck T, Ploch M & Verspohl EJ (2005) 5-HT3 receptor blocking activity of arhyalkanes isolated from the rhizome of Zingiber officinale. Planta Med 71, 609-616.
    • (2005) Planta Med , vol.71 , pp. 609-616
    • Abdel-Aziz, H.1    Nahrstedt, A.2    Peterelt, F.3    Windeck, T.4    Ploch, M.5    Verspohl, E.J.6
  • 2
    • 1042292667 scopus 로고    scopus 로고
    • Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats
    • Akhani SP, Vishwakarma SL & Goyal RK (2004) Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. J Pharm Pharmacol 56, 101-105.
    • (2004) J Pharm Pharmacol , vol.56 , pp. 101-105
    • Akhani, S.P.1    Vishwakarma, S.L.2    Goyal, R.K.3
  • 4
    • 0020048107 scopus 로고
    • Stability of the diabetogenic activity of streptozotocin
    • Axler DA (1982) Stability of the diabetogenic activity of streptozotocin. IRCS Med Sci 10, 157-165.
    • (1982) IRCS Med Sci , vol.10 , pp. 157-165
    • Axler, D.A.1
  • 5
    • 0024330279 scopus 로고
    • Traditional plant medicines as treatments for diabetes
    • Bailey CJ & Day C (1989) Traditional plant medicines as treatments for diabetes. Diabetes Care 12, 553-564.
    • (1989) Diabetes Care , vol.12 , pp. 553-564
    • Bailey, C.J.1    Day, C.2
  • 7
    • 13544263392 scopus 로고    scopus 로고
    • Effect of ethanolic extract of Zingiber officinale on dyslipidaemia in diabetic rats
    • Bhandari U, Kanojia R & Pillai KK (2005) Effect of ethanolic extract of Zingiber officinale on dyslipidaemia in diabetic rats. J Ethnopharmacol 97, 227-230.
    • (2005) J Ethnopharmacol , vol.97 , pp. 227-230
    • Bhandari, U.1    Kanojia, R.2    Pillai, K.K.3
  • 9
    • 0030978825 scopus 로고    scopus 로고
    • Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Tringonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease
    • Bordia A, Verma SK & Srivastava KC (1997) Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Tringonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostagl Leukotr Essen Fatty Acids 56, 379-384.
    • (1997) Prostagl Leukotr Essen Fatty Acids , vol.56 , pp. 379-384
    • Bordia, A.1    Verma, S.K.2    Srivastava, K.C.3
  • 10
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.1
  • 11
    • 24944481993 scopus 로고    scopus 로고
    • Gelstat Migraine® (sublingually administered feverfew and ginger compound) for acute treatment of migraine when administered during the mild pain phase
    • Cady RK, Schreiber CP, Beach ME & Hart CC (2005) Gelstat Migraine® (sublingually administered feverfew and ginger compound) for acute treatment of migraine when administered during the mild pain phase. Med Sci Monit 11, 165-169.
    • (2005) Med Sci Monit , vol.11 , pp. 165-169
    • Cady, R.K.1    Schreiber, C.P.2    Beach, M.E.3    Hart, C.C.4
  • 13
    • 0942289918 scopus 로고    scopus 로고
    • Diabetes and chronic kidney disease: Tragedy and challenge
    • Chua DY & Bakris GL (2004) Diabetes and chronic kidney disease: Tragedy and challenge. Blood Purif 22, 130-135.
    • (2004) Blood Purif , vol.22 , pp. 130-135
    • Chua, D.Y.1    Bakris, G.L.2
  • 14
    • 0029069447 scopus 로고
    • Drug therapy: Prevention and treatment of complications of diabetes mellitus
    • Clark CM & Lee DA (1995) Drug therapy: Prevention and treatment of complications of diabetes mellitus. N Engl J Med 332, 1210-1217.
    • (1995) N Engl J Med , vol.332 , pp. 1210-1217
    • Clark, C.M.1    Lee, D.A.2
  • 15
    • 0034000843 scopus 로고    scopus 로고
    • Efficacy of ginger for nausea and vomiting: A systematic review of randomized clinical trials
    • Ernst E & Pittler MH (2000) Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Brit J Anaes 84, 367-371.
    • (2000) Brit J Anaes , vol.84 , pp. 367-371
    • Ernst, E.1    Pittler, M.H.2
  • 16
    • 0034011401 scopus 로고    scopus 로고
    • Ginger extract consumption reduces plasma cholesterol, inhibits LDL oxidation and attenuates development of atherosclerosis in atherosclerotic, apolipoprotein E-deficient mice
    • Fuhrman B, Rosenblat M, Hayek T, Coleman R & Aviram M (2000) Ginger extract consumption reduces plasma cholesterol, inhibits LDL oxidation and attenuates development of atherosclerosis in atherosclerotic, apolipoprotein E-deficient mice. J Nutr 130, 1124-1131.
    • (2000) J Nutr , vol.130 , pp. 1124-1131
    • Fuhrman, B.1    Rosenblat, M.2    Hayek, T.3    Coleman, R.4    Aviram, M.5
  • 17
    • 84972893056 scopus 로고
    • Ginger - Chemistry, technology, and quality evaluation: Part 1
    • Govindarajan VS (1982a) Ginger - chemistry, technology, and quality evaluation: Part 1. Crit Rev Food Sci Nutr 17, 1-96.
    • (1982) Crit Rev Food Sci Nutr , vol.17 , pp. 1-96
    • Govindarajan, V.S.1
  • 18
    • 0020448351 scopus 로고
    • Ginger - Chemistry, technology, and quality evaluation: Part 2
    • Govindarajan VS (1982b) Ginger - chemistry, technology, and quality evaluation: Part 2. Crit Rev Food Sci Nutr 17, 189-258.
    • (1982) Crit Rev Food Sci Nutr , vol.17 , pp. 189-258
    • Govindarajan, V.S.1
  • 20
    • 0031090642 scopus 로고    scopus 로고
    • Nature's own pharmacy: The diabetes perspective
    • Gray AM & Flatt PR (1997) Nature's own pharmacy: The diabetes perspective. Proc Nutr Soc 56, 507-517.
    • (1997) Proc Nutr Soc , vol.56 , pp. 507-517
    • Gray, A.M.1    Flatt, P.R.2
  • 21
    • 0032953318 scopus 로고    scopus 로고
    • Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander)
    • Gray AM & Flatt PR (1999) Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br J Nutr 81, 203-209.
    • (1999) Br J Nutr , vol.81 , pp. 203-209
    • Gray, A.M.1    Flatt, P.R.2
  • 22
    • 0036848826 scopus 로고    scopus 로고
    • Biomarkers and functional foods for obesity and diabetes
    • Hill JO & Peters JC (2002) Biomarkers and functional foods for obesity and diabetes. Br J Nutr 88, Suppl., S213-S218.
    • (2002) Br J Nutr , vol.88 , Issue.SUPPL.
    • Hill, J.O.1    Peters, J.C.2
  • 24
    • 0037216916 scopus 로고    scopus 로고
    • Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxa diabetic rats
    • Kar A, Choudhary BK & Bandyopadhyay NG (2003) Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxa diabetic rats. J Ethnopharmacol 84, 105-108.
    • (2003) J Ethnopharmacol , vol.84 , pp. 105-108
    • Kar, A.1    Choudhary, B.K.2    Bandyopadhyay, N.G.3
  • 26
    • 0026505808 scopus 로고
    • Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids
    • Kiuchi F, Iwakami S, Shibuya M, Hanaoka F & Sankawa U (1992) Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids. Chem Pharm Bull (Tokyo) 40, 387-391.
    • (1992) Chem Pharm Bull (Tokyo) , vol.40 , pp. 387-391
    • Kiuchi, F.1    Iwakami, S.2    Shibuya, M.3    Hanaoka, F.4    Sankawa, U.5
  • 27
    • 0011758646 scopus 로고
    • Diabetes mellitus
    • In 6th ed. [LY Young, MA Koda-Kimble, WA Kradjan and BJ Guglielmo, editors]. Vancouver, BC, Canada: Applied Therapeutics
    • Koda-Kimble MA & Carlisle BA (1995) Diabetes mellitus. In Applied Therapeutics: The Clinical Use of Drugs, 6th ed. pp. 48-1-48-58 [LY Young, MA Koda-Kimble, WA Kradjan and BJ Guglielmo, editors]. Vancouver, BC, Canada: Applied Therapeutics.
    • (1995) Applied Therapeutics: The Clinical Use of Drugs
    • Koda-Kimble, M.A.1    Carlisle, B.A.2
  • 29
    • 0024791488 scopus 로고
    • Ethnopharmacologic investigation of ginger (Zingiber officinale)
    • Mascolo N, Jain R, Jain SC & Capasso F (1989) Ethnopharmacologic investigation of ginger (Zingiber officinale). J Ethnopharmacol 27, 129-140.
    • (1989) J Ethnopharmacol , vol.27 , pp. 129-140
    • Mascolo, N.1    Jain, R.2    Jain, S.C.3    Capasso, F.4
  • 30
    • 0025345973 scopus 로고
    • Ginger (Zingiber officinale) in migraine headache
    • Mustafa T & Srivastava KC (1990) Ginger (Zingiber officinale) in migraine headache. J Ethnopharmacol 29, 267-273.
    • (1990) J Ethnopharmacol , vol.29 , pp. 267-273
    • Mustafa, T.1    Srivastava, K.C.2
  • 31
    • 0027175475 scopus 로고
    • Drug development report (9): Pharmacology of ginger, Zingiber officinale
    • Mustafa T, Srivastava KC & Jensen KB (1994) Drug development report (9): Pharmacology of ginger, Zingiber officinale. J Drug Dev 6, 25-39.
    • (1994) J Drug Dev , vol.6 , pp. 25-39
    • Mustafa, T.1    Srivastava, K.C.2    Jensen, K.B.3
  • 32
    • 0348023269 scopus 로고    scopus 로고
    • Veterinary medical care
    • National Research Council In Washington, DC: National Academy Press
    • National Research Council (1996) Veterinary medical care. In Guide for the Care and Use of Laboratory Animals, pp. 56-70. Washington, DC: National Academy Press.
    • (1996) Guide for the Care and Use of Laboratory Animals , pp. 56-70
  • 33
    • 0027253061 scopus 로고
    • Long-term complications of diabetes mellitus
    • Nathan DM (1993) Long-term complications of diabetes mellitus. N Engl J Med 328, 1676-1685.
    • (1993) N Engl J Med , vol.328 , pp. 1676-1685
    • Nathan, D.M.1
  • 34
    • 0038546637 scopus 로고    scopus 로고
    • Anti-inflammatory effect of the hydralcoholic extract of Zingiber officinale rhizomes on rat paw and skin edema
    • Penna SC, Medeiros MV, Aimbire FS, Faria-Neto HC, Sertie JA & Lopes-Martins RA (2003) Anti-inflammatory effect of the hydralcoholic extract of Zingiber officinale rhizomes on rat paw and skin edema. Phytomed 10, 381-385.
    • (2003) Phytomed , vol.10 , pp. 381-385
    • Penna, S.C.1    Medeiros, M.V.2    Aimbire, F.S.3    Faria-Neto, H.C.4    Sertie, J.A.5    Lopes-Martins, R.A.6
  • 35
    • 0348011908 scopus 로고    scopus 로고
    • Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy
    • Portnoi G, Chng LA, Karimi-Tabesh L, Koren G, Tan MP & Einarson A (2003) Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy. Am J Obstet Gynecol 189, 1374-1377.
    • (2003) Am J Obstet Gynecol , vol.189 , pp. 1374-1377
    • Portnoi, G.1    Chng, L.A.2    Karimi-Tabesh, L.3    Koren, G.4    Tan, M.P.5    Einarson, A.6
  • 36
  • 37
    • 6744234753 scopus 로고
    • Glycaemic and cholesterolemic role of ginger and till
    • Singhal PC & Joshi LD (1983) Glycaemic and cholesterolemic role of ginger and till. J Sci Res Plants Med 4, 32-34.
    • (1983) J Sci Res Plants Med , vol.4 , pp. 32-34
    • Singhal, P.C.1    Joshi, L.D.2
  • 38
    • 31344441135 scopus 로고    scopus 로고
    • Plant foods in the management of diabetes mellitus: Spices as beneficial antidiabetic food adjuncts
    • Srinvasan K (2005) Plant foods in the management of diabetes mellitus: spices as beneficial antidiabetic food adjuncts. Int J Food Sci Nutr 56, 399-414.
    • (2005) Int J Food Sci Nutr , vol.56 , pp. 399-414
    • Srinvasan, K.1
  • 39
    • 0024670873 scopus 로고
    • Ginger (Zingiber officinale) and rheumatic disorders
    • Srivastava KC & Mustafa T (1989) Ginger (Zingiber officinale) and rheumatic disorders. Med Hyp 29, 25-28.
    • (1989) Med Hyp , vol.29 , pp. 25-28
    • Srivastava, K.C.1    Mustafa, T.2
  • 40
    • 0027051053 scopus 로고
    • Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders
    • Srivastava KC & Mustafa T (1992) Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hyp 39, 342-348.
    • (1992) Med Hyp , vol.39 , pp. 342-348
    • Srivastava, K.C.1    Mustafa, T.2
  • 41
    • 0026291426 scopus 로고
    • Traditional dietary adjuncts for the treatment of diabetes mellitus
    • Swanston-Flatt SK, Flatt PR, Day C & Bailey CJ (1991) Traditional dietary adjuncts for the treatment of diabetes mellitus. Proc Nutr Soc 50, 641-651.
    • (1991) Proc Nutr Soc , vol.50 , pp. 641-651
    • Swanston-Flatt, S.K.1    Flatt, P.R.2    Day, C.3    Bailey, C.J.4
  • 44
    • 0020045025 scopus 로고
    • Microalbuminuria as a predictor of clinical nephropathy in insulin dependent diabetes mellitus
    • Viberti GC, Hill RD, Jarett RJ, Argyropolous A, Mahmud U & Kern H (1982) Microalbuminuria as a predictor of clinical nephropathy in insulin dependent diabetes mellitus. Lancet i, 1430.
    • (1982) Lancet , vol.1 , pp. 1430
    • Viberti, G.C.1    Hill, R.D.2    Jarett, R.J.3    Argyropolous, A.4    Mahmud, U.5    Kern, H.6
  • 45
    • 0033697121 scopus 로고    scopus 로고
    • The safety of a ginger extract in the rat
    • Weidner M & Sigwart K (2000) The safety of a ginger extract in the rat. J Ethnopharmacol 73, 513-520.
    • (2000) J Ethnopharmacol , vol.73 , pp. 513-520
    • Weidner, M.1    Sigwart, K.2
  • 46
    • 27544439702 scopus 로고
    • Diabetes mellitus
    • In 2nd ed. [DA White and M Baxter, editors]. London: Arnold
    • White DA & Baxter M (1994) Diabetes mellitus. In Hormones and Metabolic Control, 2nd ed. pp. 79-92 [DA White and M Baxter, editors]. London: Arnold.
    • (1994) Hormones and Metabolic Control , pp. 79-92
    • White, D.A.1    Baxter, M.2
  • 48
    • 0032735751 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors fluoxetine and fluvosamine induce hyperglycemia by different mechanisms
    • Yamada J, Sugimoto Y & Inoue K (1999) Selective serotonin reuptake inhibitors fluoxetine and fluvosamine induce hyperglycemia by different mechanisms. Eur J Pharmacol 382, 211-215.
    • (1999) Eur J Pharmacol , vol.382 , pp. 211-215
    • Yamada, J.1    Sugimoto, Y.2    Inoue, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.