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Volumn 7, Issue 1, 2011, Pages 36-46

Chemopreventive potential of bitter melon (Momordica charantia) against precancerous lesions in the colon of fisher 344 male rats

Author keywords

Aberrant crypt foci; Azoxymethane; Detoxification; Momordica charantia

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; CATALASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; PHENOL; SCAVENGER; SUPEROXIDE DISMUTASE; TUMOR MARKER;

EID: 79959304427     PISSN: 18119727     EISSN: 18119735     Source Type: Journal    
DOI: 10.3923/ijcr.2011.36.46     Document Type: Article
Times cited : (13)

References (51)
  • 1
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi, H., 1984. Catalase in vitro. Methods Enzymol., 105: 121-126.
    • (1984) Methods Enzymol. , vol.105 , pp. 121-126
    • Aebi, H.1
  • 2
    • 45349096041 scopus 로고    scopus 로고
    • ACS, American Cancer Society, Atlanta
    • ACS, 2008. Cancer Facts and Figures 2008. American Cancer Society, Atlanta.
    • (2008) Cancer Facts and Figures 2008
  • 3
    • 67650385302 scopus 로고    scopus 로고
    • ACS, American Cancer Society, Atlanta
    • ACS, 2009. Cancer Facts and Figures 2009. American Cancer Society, Atlanta.
    • (2009) Cancer Facts and Figures 2009
  • 4
    • 40449084279 scopus 로고    scopus 로고
    • Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats
    • Arikawa, A.Y. and D.D. Gallaher, 2008. Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats. J. Nutr., 138: 526-532.
    • (2008) J. Nutr. , vol.138 , pp. 526-532
    • Arikawa, A.Y.1    Gallaher, D.D.2
  • 5
    • 41549143953 scopus 로고    scopus 로고
    • Simultaneous estimation of phenolic acids in sea buckthorn (Hippophae rhamnoides) using RP-HPLC with DAD
    • Arimboor, R., K. Kumar and C. Arumughan, 2008. Simultaneous estimation of phenolic acids in sea buckthorn (Hippophae rhamnoides) using RP-HPLC with DAD. J. Pharm. Biomed. Anal., 47: 30-38.
    • (2008) J. Pharm. Biomed. Anal. , vol.47 , pp. 30-38
    • Arimboor, R.1    Kumar, K.2    Arumughan, C.3
  • 6
    • 0038283005 scopus 로고    scopus 로고
    • Bitter melon (Momordica charantia): A review of efficacy and safety
    • Basch, S., E. Gabardi and C. Ulbright, 2003. Bitter melon (Momordica charantia): A review of efficacy and safety. Am. J. Health Syst. Pharm., 60: 356-359.
    • (2003) Am. J. Health Syst. Pharm. , vol.60 , pp. 356-359
    • Basch, S.1    Gabardi, E.2    Ulbright, C.3
  • 7
    • 0030586361 scopus 로고    scopus 로고
    • The ferric reducing ability of plasma as a measure of antioxidant power: The FRAP assay
    • Benzie, I.F. and J.J. Strain, 1996. The ferric reducing ability of plasma as a measure of antioxidant power: The FRAP assay. Anal. Biochem., 239: 70-76.
    • (1996) Anal. Biochem. , vol.239 , pp. 70-76
    • Benzie, I.F.1    Strain, J.J.2
  • 8
    • 0023629080 scopus 로고
    • Observation and quantification of aberrant crypt foci in murine colon treated with colon carcinogen
    • Bird, R., 1987. Observation and quantification of aberrant crypt foci in murine colon treated with colon carcinogen. Cancer Lett., 37: 147-151.
    • (1987) Cancer Lett. , vol.37 , pp. 147-151
    • Bird, R.1
  • 9
    • 33947425191 scopus 로고    scopus 로고
    • Selected fruits reduce azoxymethane (AOM)-induced Aberrant Crypt Foci (ACF) in Fisher 344 male rats
    • Boateng, J., M. Verghese, L. Shackelford, L.T. Walker and J. Khatiwada et al., 2007. Selected fruits reduce azoxymethane (AOM)-induced Aberrant Crypt Foci (ACF) in Fisher 344 male rats. Food Chem. Toxicol., 45: 725-732.
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 725-732
    • Boateng, J.1    Verghese, M.2    Shackelford, L.3    Walker, L.T.4    Khatiwada, J.5
  • 12
    • 0024308039 scopus 로고
    • Superoxide dismutase. An adaption to paramagnetic gas
    • Fridovich, I., 1989. Superoxide dismutase. An adaption to paramagnetic gas. J. Biol. Chem., 254: 7761-7764.
    • (1989) J. Biol. Chem. , vol.254 , pp. 7761-7764
    • Fridovich, I.1
  • 13
    • 2942538292 scopus 로고    scopus 로고
    • Pharmacological actions and potential uses of Momordica charantia: A review
    • Grover, J.K. and S.P. Yadav, 2004. Pharmacological actions and potential uses of Momordica charantia: A review. J. Ethnopharm., 93: 123-132.
    • (2004) J. Ethnopharm. , vol.93 , pp. 123-132
    • Grover, J.K.1    Yadav, S.P.2
  • 14
    • 43049101503 scopus 로고    scopus 로고
    • Effects of dietary protein levels and origin on the redox status in the digestive tract of mice
    • Gu, C., Y. Shi and G. Le, 2008. Effects of dietary protein levels and origin on the redox status in the digestive tract of mice. Int. J. Mol. Sci., 9: 464-475.
    • (2008) Int. J. Mol. Sci. , vol.9 , pp. 464-475
    • Gu, C.1    Shi, Y.2    Le, G.3
  • 15
    • 0016275313 scopus 로고
    • Glutathione-S-transferase, the first enzymatic step in mercapturia acid formation
    • Habig, W.H., M.J. Pabst and W.B. Jakoby, 1974. Glutathione-S-transferase, the first enzymatic step in mercapturia acid formation. J. Biol. Chem., 429: 7130-7139.
    • (1974) J. Biol. Chem. , vol.429 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 16
    • 51849127444 scopus 로고    scopus 로고
    • Red cabbage (Brassica oleracea) ameliorates diabetes nephropathy in rats
    • Hazem, A., H. Kataya and A. Hamza, 2008. Red cabbage (Brassica oleracea) ameliorates diabetes nephropathy in rats. Evid. Based Complement Altera at. Med., 5: 281-287.
    • (2008) Evid. Based Complement Altera at. Med. , vol.5 , pp. 281-287
    • Hazem, A.1    Kataya, H.2    Hamza, A.3
  • 18
    • 22444434136 scopus 로고    scopus 로고
    • Momordin Ic and oleanolic acid from Kochiae Fructus reduce carbon tetrachloride-induced hep atotoxi city in rats
    • Kim, N.Y., M.K. Lee, M.J. Park, S.J. Kim and H.J. Park et al., 2005. Momordin Ic and oleanolic acid from Kochiae Fructus reduce carbon tetrachloride-induced hep atotoxi city in rats. J. Med. Food, 8: 177-183.
    • (2005) J. Med. Food , vol.8 , pp. 177-183
    • Kim, N.Y.1    Lee, M.K.2    Park, M.J.3    Kim, S.J.4    Park, H.J.5
  • 19
    • 0036327565 scopus 로고    scopus 로고
    • Induction of apoptosis by momordin 1 in promyelocytic leukemia (HL-60) cells
    • Kim, S.J., E. Ju, D. Lee and H. Hwang, 2002. Induction of apoptosis by momordin 1 in promyelocytic leukemia (HL-60) cells. Anticancer Res., 22: 1885-1889.
    • (2002) Anticancer Res. , vol.22 , pp. 1885-1889
    • Kim, S.J.1    Ju, E.2    Lee, D.3    Hwang, H.4
  • 20
    • 33749070322 scopus 로고    scopus 로고
    • Phytochemical flavonols, carotenoids and the antioxidant properties of a wide selection of Fijian fruit, vegetable and other readily available foods
    • Lako, J., Y. Trenerry, M. Wahlqvist, N. Wattanapenpaiboon, S. Sotheeswaran and R. Premier, 2007. Phytochemical flavonols, carotenoids and the antioxidant properties of a wide selection of Fijian fruit, vegetable and other readily available foods. Food Chem., 101: 1727-1741.
    • (2007) Food Chem. , vol.101 , pp. 1727-1741
    • Lako, J.1    Trenerry, Y.2    Wahlqvist, M.3    Wattanapenpaiboon, N.4    Sotheeswaran, S.5    Premier, R.6
  • 21
    • 0026496180 scopus 로고
    • Cytotoxicity of momordin-folate conjugates in cultured human cells
    • Leamon, C. and P. Low, 1992. Cytotoxicity of momordin-folate conjugates in cultured human cells. J. Biol. Chem., 267: 24966-24971.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24966-24971
    • Leamon, C.1    Low, P.2
  • 22
    • 0029135318 scopus 로고
    • Anti-HIV and antitumor activities of recombinant MAP3Ofrom bitter melon
    • Lee-Huang, S., P. Huang, H. Chen, A. Bourinbaiar, H. Huang and H. Kuang, 1995. Anti-HIV and antitumor activities of recombinant MAP3Ofrom bitter melon. Gene, 161: 151-156.
    • (1995) Gene , vol.161 , pp. 151-156
    • Lee-Huang, S.1    Huang, P.2    Chen, H.3    Bourinbaiar, A.4    Huang, H.5    Kuang, H.6
  • 23
    • 15244357258 scopus 로고    scopus 로고
    • The change of total anthocyanins in blueberries and their antioxidant effect after drying and freezing
    • Lohachoompol, V., G. Srzednicki and J. Craske, 2004. The change of total anthocyanins in blueberries and their antioxidant effect after drying and freezing. J. Biom. Biotechnol., 2004: 248-252.
    • (2004) J. Biom. Biotechnol. , vol.2004 , pp. 248-252
    • Lohachoompol, V.1    Srzednicki, G.2    Craske, J.3
  • 24
    • 0037882042 scopus 로고    scopus 로고
    • Intake of fruits, vegetables and selected micronutrients in relation to the risk of breast cancer
    • Malm, A.S., D. Qi, X.O. Shu, Y.T. Gao, J.M. Friedmann, F. Jin and W. Zheng, 2003. Intake of fruits, vegetables and selected micronutrients in relation to the risk of breast cancer. Int. J. Cancer, 105: 413-418.
    • (2003) Int. J. Cancer , vol.105 , pp. 413-418
    • Malm, A.S.1    Qi, D.2    Shu, X.O.3    Gao, Y.T.4    Friedmann, J.M.5    Jin, F.6    Zheng, W.7
  • 25
    • 62549099985 scopus 로고    scopus 로고
    • The role of mitochondrial superoxide anion (02-) on physiological aging in C57BL/6J mice
    • Miyazawa, M., T. Ishii, K. Yasuda, S. Noda, H. Onouchi, P. Hartman and N. Ishii, 2009. The role of mitochondrial superoxide anion (02-) on physiological aging in C57BL/6J mice. J. Radiat. Res., 50: 73-82.
    • (2009) J. Radiat. Res. , vol.50 , pp. 73-82
    • Miyazawa, M.1    Ishii, T.2    Yasuda, K.3    Noda, S.4    Onouchi, H.5    Hartman, P.6    Ishii, N.7
  • 26
    • 0026720825 scopus 로고
    • Proteins with abortifacient, ribosome inactivating, immunomodulatory, antitumor and anti-AIDS activities from Cucurbitaceae plants
    • Ng, T.B., W.Y. Chan and H.W. Yeung, 1992. Proteins with abortifacient, ribosome inactivating, immunomodulatory, antitumor and anti-AIDS activities from Cucurbitaceae plants. Gen. Pharmacol., 23: 579-590.
    • (1992) Gen. Pharmacol. , vol.23 , pp. 579-590
    • Ng, T.B.1    Chan, W.Y.2    Yeung, H.W.3
  • 27
    • 69549092070 scopus 로고    scopus 로고
    • A comparative study on antioxidant activities of different varieties of Solarium melongena
    • Nisha, P., A.P. Nazar and P. Jayamurthy, 2009. A comparative study on antioxidant activities of different varieties of Solarium melongena. Food Chem. Toxi., 47: 2640-2644.
    • (2009) Food Chem. Toxi. , vol.47 , pp. 2640-2644
    • Nisha, P.1    Nazar, A.P.2    Jayamurthy, P.3
  • 28
    • 0029842309 scopus 로고    scopus 로고
    • Efficient method for rapid induction of aberrant crypt foci in rats with 2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine
    • Ochiai, M., H. Nakagama, M. Watanabe, Y. Ishiguro, T. Sugimura and M. Nagao, 1996. Efficient method for rapid induction of aberrant crypt foci in rats with 2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine. Jpn. J. Cancer Res., 87: 1029-1033.
    • (1996) Jpn. J. Cancer Res. , vol.87 , pp. 1029-1033
    • Ochiai, M.1    Nakagama, H.2    Watanabe, M.3    Ishiguro, Y.4    Sugimura, T.5    Nagao, M.6
  • 29
    • 0036765433 scopus 로고    scopus 로고
    • Radical scavenging activity and cytotoxicity of ferulic acid
    • Ogiwara, T., K. Satoh and Y. Kadoma, 2002. Radical scavenging activity and cytotoxicity of ferulic acid. Anticancer Res., 22: 2711-2717.
    • (2002) Anticancer Res. , vol.22 , pp. 2711-2717
    • Ogiwara, T.1    Satoh, K.2    Kadoma, Y.3
  • 32
    • 27844486110 scopus 로고    scopus 로고
    • Modulation of xenobiotic metabolising enzyme by anticarcinogens-focus on glutathione S-transferase and their role as targets of dietary chemoprevention in colorectal carcinogenesis
    • Pool-Zobel, B., S. Veeriah and F. Bohmer, 2005. Modulation of xenobiotic metabolising enzyme by anticarcinogens-focus on glutathione S-transferase and their role as targets of dietary chemoprevention in colorectal carcinogenesis. Mutat. Res., 591: 74-92.
    • (2005) Mutat. Res. , vol.591 , pp. 74-92
    • Pool-Zobel, B.1    Veeriah, S.2    Bohmer, F.3
  • 34
    • 22844445262 scopus 로고    scopus 로고
    • Occurrence of yellow mosaic geminiviral disease on bitter gourd (. Momordica charantia) and its impact on phytochemical contents
    • Raj, S., M. Khan, R. Singh, B. Kumari and D. Prakash, 2005. Occurrence of yellow mosaic geminiviral disease on bitter gourd (. Momordica charantia) and its impact on phytochemical contents. Int. J. Food Sci. Nutr., 56: 185-192.
    • (2005) Int. J. Food Sci. Nutr. , vol.56 , pp. 185-192
    • Raj, S.1    Khan, M.2    Singh, R.3    Kumari, B.4    Prakash, D.5
  • 35
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American institute of nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves, P.G., F.H. Nielsen and Jr. G.C. Fahey, 1993. AIN-93 purified diets for laboratory rodents: Final report of the American institute of nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr., 123: 1939-1951.
    • (1993) J. Nutr. , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen Jr., F.H.2    Fahey, G.C.3
  • 36
    • 0042284013 scopus 로고    scopus 로고
    • Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk
    • Riboli, E. and T. Norat, 2003. Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk. Am. J. Clin. Nutr., 78: 559S-569S.
    • (2003) Am. J. Clin. Nutr. , vol.78
    • Riboli, E.1    Norat, T.2
  • 37
    • 84945976637 scopus 로고    scopus 로고
    • SAS, SAS Institute Inc., Cary, North Carolina, USA
    • SAS, 2004. System Analysis Software. Version 9.1.2. SAS Institute Inc., Cary, North Carolina, USA.
    • (2004) System Analysis Software. Version 9.1.2
  • 38
  • 39
    • 69349095392 scopus 로고    scopus 로고
    • Effects of a probiotic soy product and physical exercise on formation of pre-neoplastic lesions in rat colons in a short-term model of carcinogenic
    • Silva, M.F., K. Sivieri and E.A. Ross, 2009. Effects of a probiotic soy product and physical exercise on formation of pre-neoplastic lesions in rat colons in a short-term model of carcinogenic. J. Int. Soc. Sports Nutr., 6: 17-17.
    • (2009) J. Int. Soc. Sports Nutr. , vol.6 , pp. 17-17
    • Silva, M.F.1    Sivieri, K.2    Ross, E.A.3
  • 40
    • 3042686803 scopus 로고    scopus 로고
    • Gene mutations and altered gene expression in azoxymethane-induced colon carcinogenesis in rodents
    • Takahashi, M. and K. Wakabayashi, 2004. Gene mutations and altered gene expression in azoxymethane-induced colon carcinogenesis in rodents. Cancer Sci., 95: 475-480.
    • (2004) Cancer Sci. , vol.95 , pp. 475-480
    • Takahashi, M.1    Wakabayashi, K.2
  • 41
    • 0033862109 scopus 로고    scopus 로고
    • Suppression of azoxymethane-induced colon carcinogenesis in male F344 rats by mandarin juices rich in beta-cryptoxanthin and hesperidin
    • Tanaka, T., H. Kohno, M. Murakami, R. Shimada and S. Kagami et al., 2000. Suppression of azoxymethane-induced colon carcinogenesis in male F344 rats by mandarin juices rich in beta-cryptoxanthin and hesperidin. Int. J. Cancer, 88: 146-150.
    • (2000) Int. J. Cancer , vol.88 , pp. 146-150
    • Tanaka, T.1    Kohno, H.2    Murakami, M.3    Shimada, R.4    Kagami, S.5
  • 45
    • 38049158212 scopus 로고    scopus 로고
    • Partial properties of an aspartic in bitter gourd (Momordica charantia L.) fruit and its activation by heating
    • Wang, L., M. Wang, Q. Li, T. Cai and W. Jiang, 2008a. Partial properties of an aspartic in bitter gourd (Momordica charantia L.) fruit and its activation by heating. Food Chem., 108: 496-502.
    • (2008) Food Chem. , vol.108 , pp. 496-502
    • Wang, L.1    Wang, M.2    Li, Q.3    Cai, T.4    Jiang, W.5
  • 46
    • 49049096318 scopus 로고    scopus 로고
    • Fruit quality, antioxidant capacity and flavonoid content of organically and conventionally grown blueberries
    • Wang, S., C. Chen, W. Sciarappa, C. Wang and M. Camp, 2008b. Fruit quality, antioxidant capacity and flavonoid content of organically and conventionally grown blueberries. J. Agric. Food Chem., 56: 5788-5796.
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 5788-5796
    • Wang, S.1    Chen, C.2    Sciarappa, W.3    Wang, C.4    Camp, M.5
  • 47
    • 33751345815 scopus 로고    scopus 로고
    • Flax seed oil and flax seed meal reduce the formation of Aberrant Crypt Foci (ACF) in azoxymethane-induced colon cancer in Fisher 344 male rats
    • Williams, D., M. Verghese, L.T. Walker, J. Boateng, L. Shackelford and C.B. Chawan, 2007. Flax seed oil and flax seed meal reduce the formation of Aberrant Crypt Foci (ACF) in azoxymethane-induced colon cancer in Fisher 344 male rats. Food Chem. Toxicol., 45: 153-159.
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 153-159
    • Williams, D.1    Verghese, M.2    Walker, L.T.3    Boateng, J.4    Shackelford, L.5    Chawan, C.B.6
  • 48
    • 0038687766 scopus 로고    scopus 로고
    • Pre-cancerous lesions for colorectal cancers in rodents: A new concept
    • Yamada, Y. and H. Mori, 2003. Pre-cancerous lesions for colorectal cancers in rodents: A new concept. Carcinogenesis, 24: 1015-1019.
    • (2003) Carcinogenesis , vol.24 , pp. 1015-1019
    • Yamada, Y.1    Mori, H.2
  • 49
    • 68549101554 scopus 로고    scopus 로고
    • Radical Scavenging activity of the essential oil of Silver Fir (Abies alba)
    • Yang, S., S. Jeon, E. Lee, N. Im, K. Jhee, S. Lee and I. Lee, 2009. Radical Scavenging activity of the essential oil of Silver Fir (Abies alba). J. Clin. Biochem. Nutr., 44: 253-259.
    • (2009) J. Clin. Biochem. Nutr. , vol.44 , pp. 253-259
    • Yang, S.1    Jeon, S.2    Lee, E.3    Im, N.4    Jhee, K.5    Lee, S.6    Lee, I.7
  • 51
    • 0035232765 scopus 로고    scopus 로고
    • The flavoniods, quercetin and isorhamnetin 3-O-acylglucosides diminish neutrophil oxidative metabolism and lipid peroxidation
    • Zielinska, M., A. Kostrzewa, E. Ignatowicz and J. Budzianowski, 2001. The flavoniods, quercetin and isorhamnetin 3-O-acylglucosides diminish neutrophil oxidative metabolism and lipid peroxidation. Acta. Biochimica. Polonica., 48: 183-189.
    • (2001) Acta. Biochimica. Polonica. , vol.48 , pp. 183-189
    • Zielinska, M.1    Kostrzewa, A.2    Ignatowicz, E.3    Budzianowski, J.4


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