Hypoglycaemic, hypolipidemic and antioxidant properties of tulsi (ocmum sanctum linn) on streptozotocin induced diabetes in rats

Indian Journal of Clinical Biochemistry

Volumn 16, Issue 2, 2001, Pages 190-194

  Hussain, Eshrat Halim M A ^a   Jamil, Kaiser ^a   Rao, Mala ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

Antioxidants; Diabetes mdlitus; Hypoglycemic effect; Hypolipidemic effect; Lipid peroxidation; Ocimum sanctum

Indexed keywords

EID: 33751107651     PISSN: 09701915     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02864859     Document Type: Article

References (17)

1. Satyavati, G. V., Raina, M. K. and Sharma, M. (1976) Medicinal plants of India, Indian Concial of Medical Research, New Delhi. p. 65-68.
2. Dhar, M. L , Dhar, M. M., Dhawan, B. N., Mehrotra, B. N. and Ray, C. (1968) Screening of Indian plants for biological activity. Parti. Ind. J. Exp. Biol. 6, 232-238.
3. Shukla, R., Sharma, S. B., Puri, D., Prabhu, K. M. and Murthy, P. S. (2000) Medicinal plants for treatment of diabetes mellitus. Ind. J. Clin. Biochem. 15 (August, suppl.), 169-177.
4. Pushpangadan, P. and Sobti, S. N. (1977) Medicinal properties of Ocimum (Tulsi) species and some recent investigations of their efficacy. Indian Drugs 14, 207-208.
5. Gupta, S. (1967) Pharmacognosy of leaves of different species of Ocimum (Tulsi). Ind. J. Med. Res. 2 (1), 35-38.
6. Chattopadhyay, R. R. (1993) Hypoglycaemic effect of Ocimum sanctum leaf extract, in normal and streptozotocin diabetic rats. Ind. J. Expt Biol. 31, 891-893.
7. Bhargava, K. P. and Singh N. (1991) Anti-stress activity of Ocimum sanctum Linn. Ind. J . Med. Res. 73, 443-451.
8. Rai, V. and Iyer. U. V. (1997) Effect of Tulsi (Ocimum sanctum) leaf powder supplementation on blood sugar levels, serum lipids and tissue lipids in diabetic rats. Plant Foods Hum. Nutr. 50 (1), 9-16.
9. Agrawal, P., Rai, V. and Singh, R. B. (1996). Randomized placebo-controlled, single blind trial of holy basil leaves in patients with non-insulin dependent diabetes mellitus. Int. J. Clin. Pharmacol. 34 (9), 406-409.
10. Hussain, H. E. M. A., Jamil, K. and Rao, M. (2001) Preliminary studies on the hypoglycaemic effect of Abroma augusta in alloxan diabetic rats. Ind. J. Ciln. Biochem. 16 (1), 77-80.
11. Pdiodoro, G. D. T., Arduini., R. G. LA. and Federici, G. (1984). Superoxide dismutase, reduced glutathione and Tba- reactive products in erythrocytes of patients with multiple sclerosis. Int. J. Biochem, . 16 (5), p. 505-509.
12. Hiroshi, O., Nobuko, O. and Kunio, V. (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 5, 351-358.
13. Wendel, A. (1981) Glutathione peroxidase. In: Methods in Enzymology, Ed. Jakoby, W. B. Acadamic Press, New York, U. S. A. vol. 77, p. 327-333.
14. Mohan, V., Ramachandran, A. and Vlswanathan, M. (1985) Tropical diabetes. In: The diabetes Annual I, Eds. Aiberti. K. G. M. M., Krall, LP. Elsevier Science, Amsterdam, p. 82-92.
15. Baynes, J. W. (1991) Role of oxidative stress in developments of complications of diabetes. Diabetes. 40, 405412.
16. Vernon, R. (1981) Psychoneuroendocrine influences on immunocompetence and neoplasia Science, 212, (20), 1100-1110.
17. Yagi, K. (1987) Lipid peroxides and human disease. Chem. Phys. Lipids. 45, 357-402.