-
1
-
-
10644220306
-
Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
-
Browning, J. D., L. S. Szczepaniak, R. Dobbins, P. Nuremberg, J. D. Horton, J. C. Cohen, S. M. Grundy, and H. H. Hobbs. 2004. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology. 40: 1387-1395.
-
(2004)
Hepatology
, vol.40
, pp. 1387-1395
-
-
Browning, J.D.1
Szczepaniak, L.S.2
Dobbins, R.3
Nuremberg, P.4
Horton, J.D.5
Cohen, J.C.6
Grundy, S.M.7
Hobbs, H.H.8
-
2
-
-
23444451889
-
Prevalence of and risk factors for fatty liver in a general population of Shanghai, China
-
DOI 10.1016/j.jhep.2005.02.042, PII S0168827805002795
-
Fan, J. G., J. Zhu, X. J. Li, L. Chen, L. Li, F. Dai, F. Li, and S. Y. Chen. 2005. Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. J. Hepatol. 43: 508-514. (Pubitemid 41111434)
-
(2005)
Journal of Hepatology
, vol.43
, Issue.3
, pp. 508-514
-
-
Fan, J.-G.1
Zhu, J.2
Li, X.-J.3
Chen, L.4
Li, L.5
Dai, F.6
Li, F.7
Chen, S.-Y.8
-
3
-
-
74549140993
-
Prevalence and trends in obesity among US adults, 1999-2008
-
Flegal, K. M., M. D. Carroll, C. L. Ogden, and L. R. Curtin. 2010. Prevalence and trends in obesity among US adults, 1999-2008. JAMA. 303: 235-241.
-
(2010)
JAMA
, vol.303
, pp. 235-241
-
-
Flegal, K.M.1
Carroll, M.D.2
Ogden, C.L.3
Curtin, L.R.4
-
4
-
-
73749083481
-
Global estimates of the prevalence of diabetes for 2010 and 2030
-
Shaw, J. E., R. A. Sicree, and P. Z. Zimmet. 2010. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res. Clin. Pract. 87: 4-14.
-
(2010)
Diabetes Res. Clin. Pract.
, vol.87
, pp. 4-14
-
-
Shaw, J.E.1
Sicree, R.A.2
Zimmet, P.Z.3
-
5
-
-
33750002388
-
Prevalence of fatty liver in children and adolescents
-
DOI 10.1542/peds.2006-1212
-
Schwimmer, J. B., R. Deutsch, T. Kahen, J. E. Lavine, C. Stanley, and C. Behling. 2006. Prevalence of fatty liver in children and adolescents. Pediatrics. 118: 1388-1393. (Pubitemid 46393782)
-
(2006)
Pediatrics
, vol.118
, Issue.4
, pp. 1388-1393
-
-
Schwimmer, J.B.1
Deutsch, R.2
Kahen, T.3
Lavine, J.E.4
Stanley, C.5
Behling, C.6
-
6
-
-
0023714299
-
Prevalence of fatty liver in a general population of Okinawa, Japan
-
Nomura, H., S. Kashiwagi, J. Hayashi, W. Kajiyama, S. Tani, and M. Goto. 1988. Prevalence of fatty liver in a general population of Okinawa, Japan. Jpn. J. Med. 27: 142-149.
-
(1988)
Jpn. J. Med.
, vol.27
, pp. 142-149
-
-
Nomura, H.1
Kashiwagi, S.2
Hayashi, J.3
Kajiyama, W.4
Tani, S.5
Goto, M.6
-
7
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
DOI 10.1002/hep.20701
-
Kleiner, D. E., E. M. Brunt, M. Van Natta, C. Behling, M. J. Contos, O. W. Cummings, L. D. Ferrell, Y. C. Liu, M. S. Torbenson, A. Unalp-Arida, et al. 2005. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 41: 1313-1321. (Pubitemid 40770284)
-
(2005)
Hepatology
, vol.41
, Issue.6
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
Contos, M.J.5
Cummings, O.W.6
Ferrell, L.D.7
Liu, Y.-C.8
Torbenson, M.S.9
Unalp-Arida, A.10
Yeh, M.11
McCullough, A.J.12
Sanyal, A.J.13
-
8
-
-
22344452893
-
The natural history of nonalcoholic fatty liver disease: A population-based cohort study
-
DOI 10.1053/j.gastro.2005.04.014, PII S0016508505006943
-
Adams, L. A., J. F. Lymp, J. St. Sauver, S. O. Sanderson, K. D. Lindor, A. Feldstein, and P. Angulo. 2005. The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology. 129: 113-121. (Pubitemid 41002048)
-
(2005)
Gastroenterology
, vol.129
, Issue.1
, pp. 113-121
-
-
Adams, L.A.1
Lymp, J.F.2
St, S.J.3
Sanderson, S.O.4
Lindor, K.D.5
Feldstein, A.6
Angulo, P.7
-
9
-
-
63349098164
-
Outcome after liver transplantation for NASH cirrhosis
-
Malik, S. M., M. E. deVera, P. Fontes, O. Shaikh, and J. Ahmad. 2009. Outcome after liver transplantation for NASH cirrhosis. Am. J. Transplant. 9: 782-793.
-
(2009)
Am. J. Transplant.
, vol.9
, pp. 782-793
-
-
Malik, S.M.1
DeVera, M.E.2
Fontes, P.3
Shaikh, O.4
Ahmad, J.5
-
10
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo, P. 2002. Nonalcoholic fatty liver disease. N. Engl. J. Med. 346: 1221-1231.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
11
-
-
33645963121
-
Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C
-
Sanyal, A. J., C. Banas, C. Sargeant, V. A. Luketic, R. K. Sterling, R. T. Stravitz, M. L. Shiffman, D. Heuman, A. Coterrell, R. A. Fisher, et al. 2006. Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C. Hepatology. 43: 682-689.
-
(2006)
Hepatology
, vol.43
, pp. 682-689
-
-
Sanyal, A.J.1
Banas, C.2
Sargeant, C.3
Luketic, V.A.4
Sterling, R.K.5
Stravitz, R.T.6
Shiffman, M.L.7
Heuman, D.8
Coterrell, A.9
Fisher, R.A.10
-
13
-
-
70349326750
-
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
-
Fabbrini, E., F. Magkos, B. S. Mohammed, T. Pietka, N. A. Abumrad, B. W. Patterson, A. Okunade, and S. Klein. 2009. Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proc. Natl. Acad. Sci. USA. 106: 15430-15435.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 15430-15435
-
-
Fabbrini, E.1
Magkos, F.2
Mohammed, B.S.3
Pietka, T.4
Abumrad, N.A.5
Patterson, B.W.6
Okunade, A.7
Klein, S.8
-
14
-
-
38649111018
-
Alterations in Adipose Tissue and Hepatic Lipid Kinetics in Obese Men and Women with Nonalcoholic Fatty Liver Disease
-
DOI 10.1053/j.gastro.2007.11.038, PII S0016508507021154
-
Fabbrini, E., B. S. Mohammed, F. Magkos, K. M. Korenblat, B. W. Patterson, and S. Klein. 2008. Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology. 134: 424-431. (Pubitemid 351173050)
-
(2008)
Gastroenterology
, vol.134
, Issue.2
, pp. 424-431
-
-
Fabbrini, E.1
Mohammed, B.S.2
Magkos, F.3
Korenblat, K.M.4
Patterson, B.W.5
Klein, S.6
-
15
-
-
18244387691
-
Contribution of adipose tissue and de novo lipogenesis to nonalcoholic fatty liver disease
-
Tamura, S., and I. Shimomura. 2005. Contribution of adipose tissue and de novo lipogenesis to nonalcoholic fatty liver disease. J. Clin. Invest. 115: 1139-1142.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1139-1142
-
-
Tamura, S.1
Shimomura, I.2
-
16
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
Donnelly, K. L., C. I. Smith, S. J. Schwarzenberg, J. Jessurun, M. D. Boldt, and E. J. Parks. 2005. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 115: 1343-1351.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
17
-
-
0034283596
-
Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes
-
Azzout-Marniche, D., D. Becard, C. Guichard, M. Foretz, P. Ferre, and F. Foufelle. 2000. Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes. Biochem. J. 350: 389-393.
-
(2000)
Biochem. J.
, vol.350
, pp. 389-393
-
-
Azzout-Marniche, D.1
Becard, D.2
Guichard, C.3
Foretz, M.4
Ferre, P.5
Foufelle, F.6
-
18
-
-
4043077961
-
Molecular mediators of hepatic steatosis and liver injury
-
Browning, J. D., and J. D. Horton. 2004. Molecular mediators of hepatic steatosis and liver injury. J. Clin. Invest. 114: 147-152.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 147-152
-
-
Browning, J.D.1
Horton, J.D.2
-
19
-
-
66949149506
-
Modulation of the hepatic malonyl-CoAcarnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids
-
Akkaoui, M., I. Cohen, C. Esnous, V. Lenoir, M. Sournac, J. Girard, and C. Prip-Buus. 2009. Modulation of the hepatic malonyl-CoAcarnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids. Biochem. J. 420: 429-438.
-
(2009)
Biochem. J.
, vol.420
, pp. 429-438
-
-
Akkaoui, M.1
Cohen, I.2
Esnous, C.3
Lenoir, V.4
Sournac, M.5
Girard, J.6
Prip-Buus, C.7
-
20
-
-
0017738601
-
A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis
-
McGarry, J. D., G. P. Mannaerts, and D. W. Foster. 1977. A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis. J. Clin. Invest. 60: 265-270.
-
(1977)
J. Clin. Invest.
, vol.60
, pp. 265-270
-
-
McGarry, J.D.1
Mannaerts, G.P.2
Foster, D.W.3
-
21
-
-
44649111219
-
SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease
-
Kohjima, M., N. Higuchi, M. Kato, K. Kotoh, T. Yoshimoto, T. Fujino, M. Yada, R. Yada, N. Harada, M. Enjoji, et al. 2008. SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease. Int. J. Mol. Med. 21: 507-511.
-
(2008)
Int. J. Mol. Med.
, vol.21
, pp. 507-511
-
-
Kohjima, M.1
Higuchi, N.2
Kato, M.3
Kotoh, K.4
Yoshimoto, T.5
Fujino, T.6
Yada, M.7
Yada, R.8
Harada, N.9
Enjoji, M.10
-
22
-
-
73349125811
-
Enhancement in liver SREBP-1c/PPAR-alpha ratio and steatosis in obese patients: Correlations with insulin resistance and n-3 long-chain polyunsaturated fatty acid depletion
-
Pettinelli, P., T. Del Pozo, J. Araya, R. Rodrigo, A. V. Araya, G. Smok, A. Csendes, L. Gutierrez, J. Rojas, O. Korn, et al. 2009. Enhancement in liver SREBP-1c/PPAR-alpha ratio and steatosis in obese patients: correlations with insulin resistance and n-3 long-chain polyunsaturated fatty acid depletion. Biochim. Biophys. Acta. 1792: 1080-1086.
-
(2009)
Biochim. Biophys. Acta
, vol.1792
, pp. 1080-1086
-
-
Pettinelli, P.1
Del Pozo, T.2
Araya, J.3
Rodrigo, R.4
Araya, A.V.5
Smok, G.6
Csendes, A.7
Gutierrez, L.8
Rojas, J.9
Korn, O.10
-
23
-
-
77951557942
-
Imaging appearance of severe subcapsular hepatic steatosis: Mimicking hepatic embolic infarcts
-
H'Ng M. W., and J. W. Kwek. 2010. Imaging appearance of severe subcapsular hepatic steatosis: mimicking hepatic embolic infarcts. Br. J. Radiol. 83: e98-e100.
-
(2010)
Br. J. Radiol.
, vol.83
-
-
H'Ng, M.W.1
Kwek, J.W.2
-
24
-
-
0036207720
-
Apolipoprotein synthesis in nonalcoholic steatohepatitis
-
Charlton, M., R. Sreekumar, D. Rasmussen, K. Lindor, and K. S. Nair. 2002. Apolipoprotein synthesis in nonalcoholic steatohepatitis. Hepatology. 35: 898-904.
-
(2002)
Hepatology
, vol.35
, pp. 898-904
-
-
Charlton, M.1
Sreekumar, R.2
Rasmussen, D.3
Lindor, K.4
Nair, K.S.5
-
25
-
-
0038643426
-
Inhibition of microsomal triglyceride transfer protein: Another mechanism for drug-induced steatosis in mice
-
DOI 10.1053/jhep.2003.50309
-
Letteron, P., A. Sutton, A. Mansouri, B. Fromenty, and D. Pessayre. 2003. Inhibition of microsomal triglyceride transfer protein: another mechanism for drug-induced steatosis in mice. Hepatology. 38: 133-140. (Pubitemid 36775804)
-
(2003)
Hepatology
, vol.38
, Issue.1
, pp. 133-140
-
-
Letteron, P.1
Sutton, A.2
Mansouri, A.3
Fromenty, B.4
Pessayre, D.5
-
26
-
-
0031947715
-
Steatohepatitis: A tale of two "hits"?
-
Day, C. P., and O. F. James. 1998. Steatohepatitis: a tale of two "hits"? Gastroenterology. 114: 842-845.
-
(1998)
Gastroenterology
, vol.114
, pp. 842-845
-
-
Day, C.P.1
James, O.F.2
-
27
-
-
0036783050
-
The metabolic abnormalities associated with non-alcoholic fatty liver disease
-
Haque, M., and A. J. Sanyal. 2002. The metabolic abnormalities associated with non-alcoholic fatty liver disease. Best Pract. Res. Clin. Gastroenterol. 16: 709-731.
-
(2002)
Best Pract. Res. Clin. Gastroenterol.
, vol.16
, pp. 709-731
-
-
Haque, M.1
Sanyal, A.J.2
-
28
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
Sanyal, A. J., C. Campbell-Sargent, F. Mirshahi, W. B. Rizzo, M. J. Contos, R. K. Sterling, V. A. Luketic, M. L. Shiffman, and J. N. Clore. 2001. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology. 120: 1183-1192.
-
(2001)
Gastroenterology
, vol.120
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
Rizzo, W.B.4
Contos, M.J.5
Sterling, R.K.6
Luketic, V.A.7
Shiffman, M.L.8
Clore, J.N.9
-
29
-
-
33744948514
-
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis
-
Malhi, H., S. F. Bronk, N. W. Werneburg, and G. J. Gores. 2006. Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis. J. Biol. Chem. 281: 12093-12101.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 12093-12101
-
-
Malhi, H.1
Bronk, S.F.2
Werneburg, N.W.3
Gores, G.J.4
-
30
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
-
Feldstein, A. E., A. Canbay, P. Angulo, M. Taniai, L. J. Burgart, K. D. Lindor, and G. J. Gores. 2003. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology. 125: 437-443.
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
Taniai, M.4
Burgart, L.J.5
Lindor, K.D.6
Gores, G.J.7
-
31
-
-
3042824524
-
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway
-
Feldstein, A. E., N. W. Werneburg, A. Canbay, M. E. Guicciardi, S. F. Bronk, R. Rydzewski, L. J. Burgart, and G. J. Gores. 2004. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology. 40: 185-194.
-
(2004)
Hepatology
, vol.40
, pp. 185-194
-
-
Feldstein, A.E.1
Werneburg, N.W.2
Canbay, A.3
Guicciardi, M.E.4
Bronk, S.F.5
Rydzewski, R.6
Burgart, L.J.7
Gores, G.J.8
-
32
-
-
49649096375
-
Visceral fat: A key mediator of steatohepatitis in metabolic liver disease
-
van der Poorten, D., K. L. Milner, J. Hui, A. Hodge, M. I. Trenell, J. G. Kench, R. London, T. Peduto, D. J. Chisholm, and J. George. 2008. Visceral fat: a key mediator of steatohepatitis in metabolic liver disease. Hepatology. 48: 449-457.
-
(2008)
Hepatology
, vol.48
, pp. 449-457
-
-
Van Der Poorten, D.1
Milner, K.L.2
Hui, J.3
Hodge, A.4
Trenell, M.I.5
Kench, J.G.6
London, R.7
Peduto, T.8
Chisholm, D.J.9
George, J.10
-
33
-
-
0036165809
-
Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease
-
Valenti, L., A. L. Fracanzani, P. Dongiovanni, G. Santorelli, A. Branchi, E. Taioli, G. Fiorelli, and S. Fargion. 2002. Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease. Gastroenterology. 122: 274-280. (Pubitemid 34116980)
-
(2002)
Gastroenterology
, vol.122
, Issue.2
, pp. 274-280
-
-
Valenti, L.1
Fracanzani, A.L.2
Dongiovanni, P.3
Santorelli, G.4
Branchi, A.5
Taioli, E.6
Fiorelli, G.7
Fargion, S.8
-
34
-
-
0035125052
-
The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis
-
Wigg, A. J., I. C. Roberts-Thomson, R. B. Dymock, P. J. McCarthy, R. H. Grose, and A. G. Cummins. 2001. The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis. Gut. 48: 206-211.
-
(2001)
Gut
, vol.48
, pp. 206-211
-
-
Wigg, A.J.1
Roberts-Thomson, I.C.2
Dymock, R.B.3
McCarthy, P.J.4
Grose, R.H.5
Cummins, A.G.6
-
35
-
-
3042744737
-
Beyond insulin resistance in NASH: TNF-alpha or adiponectin?
-
Hui, J. M., A. Hodge, G. C. Farrell, J. G. Kench, A. Kriketos, and J. George. 2004. Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology. 40: 46-54.
-
(2004)
Hepatology
, vol.40
, pp. 46-54
-
-
Hui, J.M.1
Hodge, A.2
Farrell, G.C.3
Kench, J.G.4
Kriketos, A.5
George, J.6
-
36
-
-
49649100197
-
Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice
-
Tomita, K., Y. Oike, T. Teratani, T. Taguchi, M. Noguchi, T. Suzuki, A. Mizutani, H. Yokoyama, R. Irie, H. Sumimoto, et al. 2008. Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice. Hepatology. 48: 458-473.
-
(2008)
Hepatology
, vol.48
, pp. 458-473
-
-
Tomita, K.1
Oike, Y.2
Teratani, T.3
Taguchi, T.4
Noguchi, M.5
Suzuki, T.6
Mizutani, A.7
Yokoyama, H.8
Irie, R.9
Sumimoto, H.10
-
37
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
Xu, A., Y. Wang, H. Keshaw, L. Y. Xu, K. S. Lam, and G. J. Cooper. 2003. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J. Clin. Invest. 112: 91-100.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
38
-
-
10844220730
-
Adiponectin and its receptors in non-alcoholic steatohepatitis
-
DOI 10.1136/gut.2003.037010
-
Kaser, S., A. Moschen, A. Cayon, A. Kaser, J. Crespo, F. Pons- Romero, C. F. Ebenbichler, J. R. Patsch, and H. Tilg. 2005. Adiponectin and its receptors in non-alcoholic steatohepatitis. Gut. 54: 117-121. (Pubitemid 40007229)
-
(2005)
Gut
, vol.54
, Issue.1
, pp. 117-121
-
-
Kaser, S.1
Maschen, A.2
Cayon, A.3
Kaser, A.4
Crespo, J.5
Pons-Romero, F.6
Ebenbichler, C.F.7
Patsch, J.R.8
Tilg, H.9
-
39
-
-
77955734496
-
Pioglitazone in the treatment of NASH: The role of adiponectin
-
Gastaldelli, A., S. Harrison, R. Belfort-Aguiar, J. Hardies, B. Balas, S. Schenker, and K. Cusi. 2010. Pioglitazone in the treatment of NASH: the role of adiponectin. Aliment. Pharmacol. Ther. 32: 769-775.
-
(2010)
Aliment. Pharmacol. Ther.
, vol.32
, pp. 769-775
-
-
Gastaldelli, A.1
Harrison, S.2
Belfort-Aguiar, R.3
Hardies, J.4
Balas, B.5
Schenker, S.6
Cusi, K.7
-
40
-
-
78249259701
-
Dietary alpha-and gamma-tocopherol supplementation attenuates lipopolysaccharide-induced oxidative stress and infl ammatory-related responses in an obese mouse model of nonalcoholic steatohepatitis
-
Chung, M. Y., S. F. Yeung, H. J. Park, J. S. Volek, and R. S. Bruno. 2010. Dietary alpha-and gamma-tocopherol supplementation attenuates lipopolysaccharide-induced oxidative stress and infl ammatory-related responses in an obese mouse model of nonalcoholic steatohepatitis. J. Nutr. Biochem. 21: 1200-1206.
-
(2010)
J. Nutr. Biochem.
, vol.21
, pp. 1200-1206
-
-
Chung, M.Y.1
Yeung, S.F.2
Park, H.J.3
Volek, J.S.4
Bruno, R.S.5
-
41
-
-
0034890078
-
Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation
-
Yang, S., H. Lin, and A. M. Diehl. 2001. Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation. Am. J. Physiol. Gastrointest. Liver Physiol. 281: G382-G392.
-
(2001)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.281
-
-
Yang, S.1
Lin, H.2
Diehl, A.M.3
-
42
-
-
33749597707
-
Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease
-
DOI 10.1111/j.1478-3231.2006.01323.x
-
Day, C. P. 2006. Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease. Liver Int. 26: 1021-1028. (Pubitemid 44541742)
-
(2006)
Liver International
, vol.26
, Issue.9
, pp. 1021-1028
-
-
Day, C.P.1
-
43
-
-
63349086412
-
Ethnic differences in hepatic steatosis: An insulin resistance paradox?
-
Guerrero, R., G. L. Vega, S. M. Grundy, and J. D. Browning. 2009. Ethnic differences in hepatic steatosis: an insulin resistance paradox? Hepatology. 49: 791-801.
-
(2009)
Hepatology
, vol.49
, pp. 791-801
-
-
Guerrero, R.1
Vega, G.L.2
Grundy, S.M.3
Browning, J.D.4
-
44
-
-
1442301512
-
Ethnic differences in the prevalence of cryptogenic cirrhosis
-
Browning, J. D., K. S. Kumar, M. H. Saboorian, and D. L. Thiele. 2004. Ethnic differences in the prevalence of cryptogenic cirrhosis. Am. J. Gastroenterol. 99: 292-298.
-
(2004)
Am. J. Gastroenterol.
, vol.99
, pp. 292-298
-
-
Browning, J.D.1
Kumar, K.S.2
Saboorian, M.H.3
Thiele, D.L.4
-
45
-
-
67650496665
-
Correlates and heritability of nonalcoholic fatty liver disease in a minority cohort
-
Wagenknecht, L. E., A. L. Scherzinger, E. R. Stamm, A. J. Hanley, J. M. Norris, Y. D. Chen, M. Bryer-Ash, S. M. Haffner, and J. I. Rotter. 2009. Correlates and heritability of nonalcoholic fatty liver disease in a minority cohort. Obesity (Silver Spring). 17: 1240-1246.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 1240-1246
-
-
Wagenknecht, L.E.1
Scherzinger, A.L.2
Stamm, E.R.3
Hanley, A.J.4
Norris, J.M.5
Chen, Y.D.6
Bryer-Ash, M.7
Haffner, S.M.8
Rotter, J.I.9
-
46
-
-
33845315534
-
Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men
-
Petersen, K. F., S. Dufour, J. Feng, D. Befroy, J. Dziura, C. Dalla Man, C. Cobelli, and G. I. Shulman. 2006. Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men. Proc. Natl. Acad. Sci. USA. 103: 18273-18277.
-
(2006)
Proc. Natl. Acad. Sci. USA.
, vol.103
, pp. 18273-18277
-
-
Petersen, K.F.1
Dufour, S.2
Feng, J.3
Befroy, D.4
Dziura, J.5
Dalla Man, C.6
Cobelli, C.7
Shulman, G.I.8
-
47
-
-
74049159942
-
Subcutaneous and visceral adipose tissue: Structural and functional differences
-
Ibrahim, M. M. 2010. Subcutaneous and visceral adipose tissue: structural and functional differences. Obes. Rev. 11: 11-18.
-
(2010)
Obes. Rev.
, vol.11
, pp. 11-18
-
-
Ibrahim, M.M.1
-
48
-
-
33845567067
-
Heritability and genetic loci of fatty liver in familial combined hyperlipidemia
-
DOI 10.1194/jlr.M600312-JLR200
-
Brouwers, M. C., R. M. Cantor, N. Kono, J. L. Yoon, C. J. van der Kallen, M. A. Bilderbeek-Beckers, M. M. van Greevenbroek, A. J. Lusis, and T. W. de Bruin. 2006. Heritability and genetic loci of fatty liver in familial combined hyperlipidemia. J. Lipid Res. 47: 2799-2807. (Pubitemid 44936093)
-
(2006)
Journal of Lipid Research
, vol.47
, Issue.12
, pp. 2799-2807
-
-
Brouwers, M.C.G.J.1
Cantor, R.M.2
Kono, N.3
Jeong, L.Y.4
Van Der, K.C.J.H.5
Bilderbeek-Beckers, M.A.L.6
Van Greevenbroek, M.M.J.7
Lusis, A.J.8
De Bruin, T.W.A.9
-
49
-
-
29844454209
-
Gender differences in lipoprotein metabolism and dietary response: Basis in hormonal differences and implications for cardiovascular disease
-
Knopp, R. H., P. Paramsothy, B. M. Retzlaff, B. Fish, C. Walden, A. Dowdy, C. Tsunehara, K. Aikawa, and M. C. Cheung. 2005. Gender differences in lipoprotein metabolism and dietary response: basis in hormonal differences and implications for cardiovascular disease. Curr. Atheroscler. Rep. 7: 472-479.
-
(2005)
Curr. Atheroscler. Rep.
, vol.7
, pp. 472-479
-
-
Knopp, R.H.1
Paramsothy, P.2
Retzlaff, B.M.3
Fish, B.4
Walden, C.5
Dowdy, A.6
Tsunehara, C.7
Aikawa, K.8
Cheung, M.C.9
-
50
-
-
65249188812
-
Heritability of nonalcoholic fatty liver disease
-
Schwimmer, J. B., M. A. Celedon, J. E. Lavine, R. Salem, N. Campbell, N. J. Schork, M. Shiehmorteza, T. Yokoo, A. Chavez, M. S. Middleton, et al. 2009. Heritability of nonalcoholic fatty liver disease. Gastroenterology. 136: 1585-1592.
-
(2009)
Gastroenterology
, vol.136
, pp. 1585-1592
-
-
Schwimmer, J.B.1
Celedon, M.A.2
Lavine, J.E.3
Salem, R.4
Campbell, N.5
Schork, N.J.6
Shiehmorteza, M.7
Yokoo, T.8
Chavez, A.9
Middleton, M.S.10
-
51
-
-
65249120837
-
Genetics of common obesity and nonalcoholic fatty liver disease
-
Speliotes, E. K. 2009. Genetics of common obesity and nonalcoholic fatty liver disease. Gastroenterology. 136: 1492-1495.
-
(2009)
Gastroenterology
, vol.136
, pp. 1492-1495
-
-
Speliotes, E.K.1
-
52
-
-
0033826953
-
The role of the microsomal triglygeride transfer protein in abetalipoproteinemia
-
Berriot-Varoqueaux, N., L. P. Aggerbeck, M. Samson-Bouma, and J. R. Wetterau. 2000. The role of the microsomal triglygeride transfer protein in abetalipoproteinemia. Annu. Rev. Nutr. 20: 663-697.
-
(2000)
Annu. Rev. Nutr.
, vol.20
, pp. 663-697
-
-
Berriot-Varoqueaux, N.1
Aggerbeck, L.P.2
Samson-Bouma, M.3
Wetterau, J.R.4
-
53
-
-
0000683245
-
Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins
-
C. R. Scriver, A. L. Beaudet, W. S. Sly, D. Valle, B. Childs, K. Kinzler, and B. Vogelstein, editors. McGraw-Hill, New York
-
Kane, J. P., and R. J. Havel. 2001. Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins. In The Metabolic and Molecular Bases of Inherited Disease. C. R. Scriver, A. L. Beaudet, W. S. Sly, D. Valle, B. Childs, K. Kinzler, and B. Vogelstein, editors. McGraw-Hill, New York. 2717-2752.
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease
, pp. 2717-2752
-
-
Kane, J.P.1
Havel, R.J.2
-
54
-
-
30344464375
-
Monogenic hypocholesterolaemic lipid disorders and apolipoprotein B metabolism
-
Hooper, A. J., F. M. van Bockxmeer, and J. R. Burnett. 2005. Monogenic hypocholesterolaemic lipid disorders and apolipoprotein B metabolism. Crit. Rev. Clin. Lab. Sci. 42: 515-545.
-
(2005)
Crit. Rev. Clin. Lab. Sci.
, vol.42
, pp. 515-545
-
-
Hooper, A.J.1
Van Bockxmeer, F.M.2
Burnett, J.R.3
-
55
-
-
0021749724
-
Morphologic features of the liver in abetalipoproteinemia
-
Avigan, M. I., K. G. Ishak, R. E. Gregg, and J. H. Hoofnagle. 1984. Morphologic features of the liver in abetalipoproteinemia. Hepatology. 4: 1223-1226.
-
(1984)
Hepatology
, vol.4
, pp. 1223-1226
-
-
Avigan, M.I.1
Ishak, K.G.2
Gregg, R.E.3
Hoofnagle, J.H.4
-
56
-
-
0025834249
-
Intestinal and hepatic apolipoprotein B gene expression in abetalipoproteinemia
-
Black, D. D., R. V. Hay, P. L. Rohwer-Nutter, H. Ellinas, J. K. Stephens, H. Sherman, B. B. Teng, P. F. Whitington, and N. O. Davidson. 1991. Intestinal and hepatic apolipoprotein B gene expression in abetalipoproteinemia. Gastroenterology. 101: 520-528
-
(1991)
Gastroenterology
, vol.101
, pp. 520-528
-
-
Black, D.D.1
Hay, R.V.2
Rohwer-Nutter, P.L.3
Ellinas, H.4
Stephens, J.K.5
Sherman, H.6
Teng, B.B.7
Whitington, P.F.8
Davidson, N.O.9
-
57
-
-
0031837043
-
Persistence of the intestinal defect in abetalipoproteinaemia after liver transplantation
-
Braegger, C. P., D. C. Belli, G. Mentha, and B. Steinmann. 1998. Persistence of the intestinal defect in abetalipoproteinaemia after liver transplantation. Eur. J. Pediatr. 157: 576-578.
-
(1998)
Eur. J. Pediatr.
, vol.157
, pp. 576-578
-
-
Braegger, C.P.1
Belli, D.C.2
Mentha, G.3
Steinmann, B.4
-
58
-
-
0018927717
-
Abetalipoproteinemia. Report of two cases and review of therapy
-
Illingworth, D. R., W. E. Connor, and R. G. Miller. 1980. Abetalipoproteinemia. Report of two cases and review of therapy. Arch. Neurol. 37: 659-662.
-
(1980)
Arch. Neurol.
, vol.37
, pp. 659-662
-
-
Illingworth, D.R.1
Connor, W.E.2
Miller, R.G.3
-
59
-
-
0016157763
-
Liver ultrastructure in abetalipoproteinemia: Evolution of micronodular cirrhosis
-
Partin, J. S., J. C. Partin, W. K. Schubert, and A. J. McAdams. 1974. Liver ultrastructure in abetalipoproteinemia: Evolution of micronodular cirrhosis. Gastroenterology. 67: 107-118.
-
(1974)
Gastroenterology
, vol.67
, pp. 107-118
-
-
Partin, J.S.1
Partin, J.C.2
Schubert, W.K.3
McAdams, A.J.4
-
60
-
-
0027428820
-
Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia
-
DOI 10.1038/365065a0
-
Sharp, D., L. Blinderman, K. A. Combs, B. Kienzle, B. Ricci, K. Wager-Smith, C. M. Gil, C. W. Turck, M. E. Bouma, D. J. Rader, et al. 1993. Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia. Nature. 365: 65-69. (Pubitemid 23305570)
-
(1993)
Nature
, vol.365
, Issue.6441
, pp. 65-69
-
-
Sharp, D.1
Blinderman, L.2
Combs, K.A.3
Kienzle, B.4
Ricci, B.5
Wager-Smith, K.6
Gil, C.M.7
Turck, C.W.8
Bouma, M.-E.9
Rader, D.J.10
Aggerbeck, L.P.11
Gregg, R.E.12
Gordon, D.A.13
Wetterau, J.R.14
-
61
-
-
0027716370
-
Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein
-
Shoulders, C. C., D. J. Brett, J. D. Bayliss, T. M. Narcisi, A. Jarmuz, T. T. Grantham, P. R. Leoni, S. Bhattacharya, R. J. Pease, P. M. Cullen, et al. 1993. Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein. Hum. Mol. Genet. 2: 2109-2116.
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 2109-2116
-
-
Shoulders, C.C.1
Brett, D.J.2
Bayliss, J.D.3
Narcisi, T.M.4
Jarmuz, A.5
Grantham, T.T.6
Leoni, P.R.7
Bhattacharya, S.8
Pease, R.J.9
Cullen, P.M.10
-
62
-
-
33846671059
-
MTP inhibition as a treatment for dyslipidaemias: Time to deliver or empty promises?
-
Burnett, J. R., and G. F. Watts. 2007. MTP inhibition as a treatment for dyslipidaemias: time to deliver or empty promises? Expert Opin. Ther. Targets. 11: 181-189.
-
(2007)
Expert Opin. Ther. Targets.
, vol.11
, pp. 181-189
-
-
Burnett, J.R.1
Watts, G.F.2
-
63
-
-
56549091924
-
New approaches to target microsomal triglyceride transfer protein
-
Hussain, M. M., and A. Bakillah. 2008. New approaches to target microsomal triglyceride transfer protein. Curr. Opin. Lipidol. 19: 572-578.
-
(2008)
Curr. Opin. Lipidol.
, vol.19
, pp. 572-578
-
-
Hussain, M.M.1
Bakillah, A.2
-
64
-
-
77749240456
-
Lomitapide, a microsomal triglyceride transfer protein inhibitor for the treatment of hypercholesterolemia
-
Rizzo, M. 2010. Lomitapide, a microsomal triglyceride transfer protein inhibitor for the treatment of hypercholesterolemia. IDrugs. 13: 103-111.
-
(2010)
IDrugs
, vol.13
, pp. 103-111
-
-
Rizzo, M.1
-
65
-
-
48349088178
-
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia
-
Samaha, F. F., J. McKenney, L. T. Bloedon, W. J. Sasiela, and D. J. Rader. 2008. Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. Nat. Clin. Pract. Cardiovasc. Med. 5: 497-505.
-
(2008)
Nat. Clin. Pract. Cardiovasc. Med.
, vol.5
, pp. 497-505
-
-
Samaha, F.F.1
McKenney, J.2
Bloedon, L.T.3
Sasiela, W.J.4
Rader, D.J.5
-
66
-
-
69149090880
-
Future challenges for microsomal transport protein inhibitors
-
Wierzbicki, A. S., T. Hardman, and W. T. Prince. 2009. Future challenges for microsomal transport protein inhibitors. Curr. Vasc. Pharmacol. 7: 277-286.
-
(2009)
Curr. Vasc. Pharmacol.
, vol.7
, pp. 277-286
-
-
Wierzbicki, A.S.1
Hardman, T.2
Prince, W.T.3
-
67
-
-
77955294460
-
Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function
-
Zeissig, S., S. K. Dougan, D. C. Barral, Y. Junker, Z. Chen, A. Kaser, M. Ho, H. Mandel, A. McIntyre, S. M. Kennedy, et al. 2010. Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. J. Clin. Invest. 120: 2889-2899.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2889-2899
-
-
Zeissig, S.1
Dougan, S.K.2
Barral, D.C.3
Junker, Y.4
Chen, Z.5
Kaser, A.6
Ho, M.7
Mandel, H.8
McIntyre, A.9
Kennedy, S.M.10
-
68
-
-
11144315979
-
Liver dysfunction and steatosis in familial hypobetalipoproteinemia
-
Whitfield, A. J., P. H. Barrett, K. Robertson, M. F. Havlat, F. M. van Bockxmeer, and J. R. Burnett. 2005. Liver dysfunction and steatosis in familial hypobetalipoproteinemia. Clin. Chem. 51: 266-269.
-
(2005)
Clin. Chem.
, vol.51
, pp. 266-269
-
-
Whitfield, A.J.1
Barrett, P.H.2
Robertson, K.3
Havlat, M.F.4
Van Bockxmeer, F.M.5
Burnett, J.R.6
-
69
-
-
0031058121
-
Fatty liver in a case with heterozygous familial hypobetalipoproteinemia
-
Ogata, H., K. Akagi, M. Baba, A. Nagamatsu, N. Suzuki, K. Nomiyama, and M. Fujishima. 1997. Fatty liver in a case with heterozygous familial hypobetalipoproteinemia. Am. J. Gastroenterol. 92: 339-342.
-
(1997)
Am. J. Gastroenterol.
, vol.92
, pp. 339-342
-
-
Ogata, H.1
Akagi, K.2
Baba, M.3
Nagamatsu, A.4
Suzuki, N.5
Nomiyama, K.6
Fujishima, M.7
-
70
-
-
0038620476
-
Fatty liver in familial hypobetalipoproteinemia: Triglyceride assembly into VLDL particles is affected by the extent of hepatic steatosis
-
DOI 10.1194/jlr.M200342-JLR200
-
Schonfeld, G., B. W. Patterson, D. A. Yablonskiy, T. S. Tanoli, M. Averna, N. Elias, P. Yue, and J. Ackerman. 2003. Fatty liver in familial hypobetalipoproteinemia: triglyceride assembly into VLDL particles is affected by the extent of hepatic steatosis. J. Lipid Res. 44: 470-478. (Pubitemid 37279694)
-
(2003)
Journal of Lipid Research
, vol.44
, Issue.3
, pp. 470-478
-
-
Schonfeld, G.1
Patterson, B.W.2
Yablonskiy, D.A.3
Tanoli, T.S.K.4
Averna, M.5
Elias, N.6
Yue, P.7
Ackerman, J.8
-
71
-
-
2142762456
-
Fatty liver in familial hypobetalipoproteinemia: Roles of the APOB defects, intra-abdominal adipose tissue, and insulin sensitivity
-
DOI 10.1194/jlr.M300508-JLR200
-
Tanoli, T., P. Yue, D. Yablonskiy, and G. Schonfeld. 2004. Fatty liver in familial hypobetalipoproteinemia: roles of the APOB defects, intra-abdominal adipose tissue, and insulin sensitivity. J. Lipid Res. 45: 941-947. (Pubitemid 38552865)
-
(2004)
Journal of Lipid Research
, vol.45
, Issue.5
, pp. 941-947
-
-
Tanoli, T.1
Yue, P.2
Yablonskiy, D.3
Schonfeld, G.4
-
72
-
-
0033845820
-
A study of fatty liver disease and plasma lipoprotiens in a kindred with familial hypobetalipoproteinemia due to a novel truncated form of apolipoprotein B (apo B-54.5)
-
DOI 10.1016/S0168-8278(00)80270-6
-
Tarugi, P., A. Lonardo, G. Ballarini, L. Erspamer, E. Tondelli, S. Bertolini, and S. Calandra. 2000. A study of fatty liver disease and plasma lipoproteins in a kindred with familial hypobetalipoproteinemia due to a novel truncated form of apolipoprotein B (APO B-54.5). J. Hepatol. 33: 361-370. (Pubitemid 30663372)
-
(2000)
Journal of Hepatology
, vol.33
, Issue.3
, pp. 361-370
-
-
Tarugi, P.1
Lonardo, A.2
Ballarini, G.3
Erspamer, L.4
Tondelli, E.5
Bertolini, S.6
Calandra, S.7
-
73
-
-
0029796614
-
Fatty liver in heterozygous hypobetalipoproteinemia caused by a novel truncated form of apolipoprotein B
-
Tarugi, P., A. Lonardo, G. Ballarini, A. Grisendi, M. Pulvirenti, A. Bagni, and S. Calandra. 1996. Fatty liver in heterozygous hypobetalipoproteinemia caused by a novel truncated form of apolipoprotein B. Gastroenterology. 111: 1125-1133. (Pubitemid 26327617)
-
(1996)
Gastroenterology
, vol.111
, Issue.4
, pp. 1125-1133
-
-
Tarugi, P.1
Lonardo, A.2
Ballarini, G.3
Grisendi, A.4
Pulvirenti, M.5
Bagni, A.6
Calandra, S.7
-
74
-
-
0031771856
-
Frequency of ApoB and ApoE gene mutations as causes of hypobetalipoproteinemia in the Framingham Offspring population
-
Welty, F. K., C. Lahoz, K. L. Tucker, J. M. Ordovas, P. W. Wilson, and E. J. Schaefer. 1998. Frequency of ApoB and ApoE gene mutations as causes of hypobetalipoproteinemia in the Framingham Offspring population. Arterioscler. Thromb. Vasc. Biol. 18: 1745-1751.
-
(1998)
Arterioscler. Thromb. Vasc. Biol.
, vol.18
, pp. 1745-1751
-
-
Welty, F.K.1
Lahoz, C.2
Tucker, K.L.3
Ordovas, J.M.4
Wilson, P.W.5
Schaefer, E.J.6
-
75
-
-
49549118725
-
Variable phenotypic expression of homozygous familial hypobetalipoproteinaemia due to novel APOB gene mutations
-
Di Leo, E., L. Magnolo, M. Bertolotti, M. Bourbon, S. Carmo Pereira, M. Pirisi, S. Calandra, and P. Tarugi. 2008. Variable phenotypic expression of homozygous familial hypobetalipoproteinaemia due to novel APOB gene mutations. Clin. Genet. 74: 267-273.
-
(2008)
Clin. Genet.
, vol.74
, pp. 267-273
-
-
Di Leo, E.1
Magnolo, L.2
Bertolotti, M.3
Bourbon, M.4
Carmo Pereira, S.5
Pirisi, M.6
Calandra, S.7
Tarugi, P.8
-
76
-
-
57049175884
-
Apolipoprotein B gene mutations and fatty liver in Japanese hypobetalipoproteinemia
-
Katsuda, S., M. A. Kawashiri, A. Inazu, H. Tada, M. Tsuchida, Y. Kaneko, T. Nozue, A. Nohara, T. Okada, J. Kobayashi, et al. 2009. Apolipoprotein B gene mutations and fatty liver in Japanese hypobetalipoproteinemia. Clin. Chim. Acta. 399: 64-68.
-
(2009)
Clin. Chim. Acta
, vol.399
, pp. 64-68
-
-
Katsuda, S.1
Kawashiri, M.A.2
Inazu, A.3
Tada, H.4
Tsuchida, M.5
Kaneko, Y.6
Nozue, T.7
Nohara, A.8
Okada, T.9
Kobayashi, J.10
-
77
-
-
4644229798
-
Lipid disorders and mutations in the APOB gene
-
Whitfield, A. J., P. H. Barrett, F. M. van Bockxmeer, and J. R. Burnett. 2004. Lipid disorders and mutations in the APOB gene. Clin. Chem. 50: 1725-1732.
-
(2004)
Clin. Chem.
, vol.50
, pp. 1725-1732
-
-
Whitfield, A.J.1
Barrett, P.H.2
Van Bockxmeer, F.M.3
Burnett, J.R.4
-
78
-
-
0038306862
-
A novel nontruncating APOB gene mutation, R463W, causes familial hypobetalipoproteinemia
-
Burnett, J. R., J. Shan, B. A. Miskie, A. J. Whitfield, J. Yuan, K. Tran, C. J. McKnight, R. A. Hegele, and Z. Yao. 2003. A novel nontruncating APOB gene mutation, R463W, causes familial hypobetalipoproteinemia. J. Biol. Chem. 278: 13442-13452.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13442-13452
-
-
Burnett, J.R.1
Shan, J.2
Miskie, B.A.3
Whitfield, A.J.4
Yuan, J.5
Tran, K.6
McKnight, C.J.7
Hegele, R.A.8
Yao, Z.9
-
79
-
-
34548277608
-
Missense mutations in APOB within the betaalpha1 domain of human APOB-100 result in impaired secretion of ApoB and ApoB-containing lipoproteins in familial hypobetalipoproteinemia
-
Burnett, J. R., S. Zhong, Z. G. Jiang, A. J. Hooper, E. A. Fisher, R. S. McLeod, Y. Zhao, P. H. Barrett, R. A. Hegele, F. M. van Bockxmeer, et al. 2007. Missense mutations in APOB within the betaalpha1 domain of human APOB-100 result in impaired secretion of ApoB and ApoB-containing lipoproteins in familial hypobetalipoproteinemia. J. Biol. Chem. 282: 24270-24283.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24270-24283
-
-
Burnett, J.R.1
Zhong, S.2
Jiang, Z.G.3
Hooper, A.J.4
Fisher, E.A.5
McLeod, R.S.6
Zhao, Y.7
Barrett, P.H.8
Hegele, R.A.9
Van Bockxmeer, F.M.10
-
80
-
-
77949898407
-
Nonsynonymous mutations within APOB in human familial hypobetalipoproteinemia: Evidence for feedback inhibition of lipogenesis and postendoplasmic reticulum degradation of apolipoprotein B
-
Zhong, S., A. L. Magnolo, M. Sundaram, H. Zhou, E. F. Yao, E. Di Leo, P. Loria, S. Wang, M. Bamji-Mirza, L. Wang, et al. 2010. Nonsynonymous mutations within APOB in human familial hypobetalipoproteinemia: evidence for feedback inhibition of lipogenesis and postendoplasmic reticulum degradation of apolipoprotein B. J. Biol. Chem. 285: 6453-6464.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6453-6464
-
-
Zhong, S.1
Magnolo, A.L.2
Sundaram, M.3
Zhou, H.4
Yao, E.F.5
Di Leo, E.6
Loria, P.7
Wang, S.8
Bamji-Mirza, M.9
Wang, L.10
-
81
-
-
24144487681
-
Hepatic and cardiovascular consequences of familial hypobetalipoproteinemia
-
Sankatsing, R. R., S. W. Fouchier, S. de Haan, B. A. Hutten, E. de Groot, J. J. Kastelein, and E. S. Stroes. 2005. Hepatic and cardiovascular consequences of familial hypobetalipoproteinemia. Arterioscler. Thromb. Vasc. Biol. 25: 1979-1984.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 1979-1984
-
-
Sankatsing, R.R.1
Fouchier, S.W.2
De Haan, S.3
Hutten, B.A.4
De Groot, E.5
Kastelein, J.J.6
Stroes, E.S.7
-
82
-
-
0032698343
-
Decreased production rates of VLDL triglycerides and ApoB-100 in subjects heterozygous for familial hypobetalipoproteinemia
-
Elias, N., B. W. Patterson, and G. Schonfeld. 1999. Decreased production rates of VLDL triglycerides and ApoB-100 in subjects heterozygous for familial hypobetalipoproteinemia. Arterioscler. Thromb. Vasc. Biol. 19: 2714-2721.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 2714-2721
-
-
Elias, N.1
Patterson, B.W.2
Schonfeld, G.3
-
83
-
-
33646866152
-
A targeted apoB38.9 mutation in mice is associated with reduced hepatic cholesterol synthesis and enhanced lipid peroxidation
-
Lin, X., Z. Chen, P. Yue, M. R. Averna, R. E. Ostlund, Jr., M. A. Watson, and G. Schonfeld. 2006. A targeted apoB38.9 mutation in mice is associated with reduced hepatic cholesterol synthesis and enhanced lipid peroxidation. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G1170-G1176.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.290
-
-
Lin, X.1
Chen, Z.2
Yue, P.3
Averna, M.R.4
Ostlund Jr., R.E.5
Watson, M.A.6
Schonfeld, G.7
-
84
-
-
0036124635
-
Hepatic fatty acid synthesis is suppressed in mice with fatty livers due to targeted apolipoprotein B38.9 mutation
-
Lin, X., G. Schonfeld, P. Yue, and Z. Chen. 2002. Hepatic fatty acid synthesis is suppressed in mice with fatty livers due to targeted apolipoprotein B38.9 mutation. Arterioscler. Thromb. Vasc. Biol. 22: 476-482.
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 476-482
-
-
Lin, X.1
Schonfeld, G.2
Yue, P.3
Chen, Z.4
-
85
-
-
21744440377
-
Reduced intestinal fat absorptive capacity but enhanced susceptibility to diet-induced fatty liver in mice heterozygous for ApoB38.9 truncation
-
Lin, X., P. Yue, Y. Xie, N. O. Davidson, N. Sakata, R. E. Ostlund, Jr., Z. Chen, and G. Schonfeld. 2005. Reduced intestinal fat absorptive capacity but enhanced susceptibility to diet-induced fatty liver in mice heterozygous for ApoB38.9 truncation. Am. J. Physiol. Gastrointest. Liver Physiol. 289: G146-G152.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.289
-
-
Lin, X.1
Yue, P.2
Xie, Y.3
Davidson, N.O.4
Sakata, N.5
Ostlund Jr., R.E.6
Chen, Z.7
Schonfeld, G.8
-
86
-
-
77953893410
-
Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia
-
Amaro, A., E. Fabbrini, M. Kars, P. Yue, K. Schechtman, G. Schonfeld, and S. Klein. 2010. Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia. Gastroenterology. 139: 149-153.
-
(2010)
Gastroenterology
, vol.139
, pp. 149-153
-
-
Amaro, A.1
Fabbrini, E.2
Kars, M.3
Yue, P.4
Schechtman, K.5
Schonfeld, G.6
Klein, S.7
-
87
-
-
0033037729
-
The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein
-
Kobayashi, K., D. S. Sinasac, M. Iijima, A. P. Boright, L. Begum, J. R. Lee, T. Yasuda, S. Ikeda, R. Hirano, H. Terazono, et al. 1999. The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein. Nat. Genet. 22: 159-163.
-
(1999)
Nat. Genet.
, vol.22
, pp. 159-163
-
-
Kobayashi, K.1
Sinasac, D.S.2
Iijima, M.3
Boright, A.P.4
Begum, L.5
Lee, J.R.6
Yasuda, T.7
Ikeda, S.8
Hirano, R.9
Terazono, H.10
-
88
-
-
12144289341
-
Adult-onset type II citrullinemia and idiopathic neonatal hepatitis caused by citrin deficiency: Involvement of the aspartate glutamate carrier for urea synthesis and maintenance of the urea cycle
-
Saheki, T., K. Kobayashi, M. Iijima, M. Horiuchi, L. Begum, M. A. Jalil, M. X. Li, Y. B. Lu, M. Ushikai, A. Tabata, et al. 2004. Adult-onset type II citrullinemia and idiopathic neonatal hepatitis caused by citrin deficiency: involvement of the aspartate glutamate carrier for urea synthesis and maintenance of the urea cycle. Mol. Genet. Metab. 81 ( Suppl 1 ): S20-S26.
-
(2004)
Mol. Genet. Metab.
, vol.81
, Issue.SUPPL. 1
-
-
Saheki, T.1
Kobayashi, K.2
Iijima, M.3
Horiuchi, M.4
Begum, L.5
Jalil, M.A.6
Li, M.X.7
Lu, Y.B.8
Ushikai, M.9
Tabata, A.10
-
89
-
-
44449175969
-
Identification of 13 novel mutations including a retrotransposal insertion in SLC25A13 gene and frequency of 30 mutations found in patients with citrin deficiency
-
Tabata, A., J. S. Sheng, M. Ushikai, Y. Z. Song, H. Z. Gao, Y. B. Lu, F. Okumura, M. Iijima, K. Mutoh, S. Kishida, et al. 2008. Identification of 13 novel mutations including a retrotransposal insertion in SLC25A13 gene and frequency of 30 mutations found in patients with citrin deficiency. J. Hum. Genet. 53: 534-545.
-
(2008)
J. Hum. Genet.
, vol.53
, pp. 534-545
-
-
Tabata, A.1
Sheng, J.S.2
Ushikai, M.3
Song, Y.Z.4
Gao, H.Z.5
Lu, Y.B.6
Okumura, F.7
Iijima, M.8
Mutoh, K.9
Kishida, S.10
-
90
-
-
29144480108
-
Metabolic derangements in deficiency of citrin, a liver-type mitochondrial aspartate-glutamate carrier
-
Saheki, T., K. Kobayashi, M. Iijima, M. Moriyama, M. Yazaki, Y. Takei, and S. Ikeda. 2005. Metabolic derangements in deficiency of citrin, a liver-type mitochondrial aspartate-glutamate carrier. Hepatol. Res. 33: 181-184.
-
(2005)
Hepatol. Res.
, vol.33
, pp. 181-184
-
-
Saheki, T.1
Kobayashi, K.2
Iijima, M.3
Moriyama, M.4
Yazaki, M.5
Takei, Y.6
Ikeda, S.7
-
91
-
-
28844465140
-
Adult onset type II citrullinemia as a cause of non-alcoholic steatohepatitis
-
DOI 10.1016/j.jhep.2005.08.024, PII S0168827805006057
-
Takagi, H., S. Hagiwara, H. Hashizume, D. Kanda, K. Sato, N. Sohara, S. Kakizaki, H. Takahashi, M. Mori, H. Kaneko, et al. 2006. Adult onset type II citrullinemia as a cause of non-alcoholic steatohepatitis. J. Hepatol. 44: 236-239. (Pubitemid 41772540)
-
(2006)
Journal of Hepatology
, vol.44
, Issue.1
, pp. 236-239
-
-
Takagi, H.1
Hagiwara, S.2
Hashizume, H.3
Kanda, D.4
Sato, K.5
Sohara, N.6
Kakizaki, S.7
Takahashi, H.8
Mori, M.9
Kaneko, H.10
Ohwada, S.11
Ushikai, M.12
Kobayashi, K.13
Saheki, T.14
-
92
-
-
53249111691
-
Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease
-
Komatsu, M., M. Yazaki, N. Tanaka, K. Sano, E. Hashimoto, Y. Takei, Y. Z. Song, E. Tanaka, K. Kiyosawa, T. Saheki, et al. 2008. Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease. J. Hepatol. 49: 810-820.
-
(2008)
J. Hepatol.
, vol.49
, pp. 810-820
-
-
Komatsu, M.1
Yazaki, M.2
Tanaka, N.3
Sano, K.4
Hashimoto, E.5
Takei, Y.6
Song, Y.Z.7
Tanaka, E.8
Kiyosawa, K.9
Saheki, T.10
-
94
-
-
17944378173
-
Citrin and aralar1 are Ca(2+)-stimulated aspartate/ glutamate transporters in mitochondria
-
Palmieri, L., B. Pardo, F. M. Lasorsa, A. del Arco, K. Kobayashi, M. Iijima, M. J. Runswick, J. E. Walker, T. Saheki, J. Satrustegui, et al. 2001. Citrin and aralar1 are Ca(2+)-stimulated aspartate/ glutamate transporters in mitochondria. EMBO J. 20: 5060-5069.
-
(2001)
EMBO J.
, vol.20
, pp. 5060-5069
-
-
Palmieri, L.1
Pardo, B.2
Lasorsa, F.M.3
Del Arco, A.4
Kobayashi, K.5
Iijima, M.6
Runswick, M.J.7
Walker, J.E.8
Saheki, T.9
Satrustegui, J.10
-
95
-
-
0036299910
-
Mitochondrial aspartate glutamate carrier (citrin) deficiency as the cause of adult-onset type II citrullinemia (CTLN2) and idiopathic neonatal hepatitis (NICCD)
-
DOI 10.1007/s100380200046
-
Saheki, T., and K. Kobayashi. 2002. Mitochondrial aspartate glutamate carrier (citrin) deficiency as the cause of adult-onset type II citrullinemia (CTLN2) and idiopathic neonatal hepatitis (NICCD). J. Hum. Genet. 47: 333-341. (Pubitemid 34733510)
-
(2002)
Journal of Human Genetics
, vol.47
, Issue.7
, pp. 333-341
-
-
Saheki, T.1
Kobayashi, K.2
-
96
-
-
20244380465
-
A possible mechanism of neonatal intrahepatic cholestasis caused by citrin deficiency
-
Tazawa, Y., D. Abukawa, O. Sakamoto, I. Nagata, J. Murakami, T. Iizuka, M. Okamoto, A. Kimura, T. Kurosawa, K. Iinuma, et al. 2005. A possible mechanism of neonatal intrahepatic cholestasis caused by citrin deficiency. Hepatol. Res. 31: 168-171.
-
(2005)
Hepatol. Res.
, vol.31
, pp. 168-171
-
-
Tazawa, Y.1
Abukawa, D.2
Sakamoto, O.3
Nagata, I.4
Murakami, J.5
Iizuka, T.6
Okamoto, M.7
Kimura, A.8
Kurosawa, T.9
Iinuma, K.10
-
97
-
-
8144223477
-
Clinical heterogeneity of neonatal intrahepatic cholestasis caused by citrin deficiency: Case reports from 16 patients
-
Tazawa, Y., K. Kobayashi, D. Abukawa, I. Nagata, S. Maisawa, R. Sumazaki, T. Iizuka, Y. Hosoda, M. Okamoto, J. Murakami, et al. 2004. Clinical heterogeneity of neonatal intrahepatic cholestasis caused by citrin deficiency: case reports from 16 patients. Mol. Genet. Metab. 83: 213-219.
-
(2004)
Mol. Genet. Metab.
, vol.83
, pp. 213-219
-
-
Tazawa, Y.1
Kobayashi, K.2
Abukawa, D.3
Nagata, I.4
Maisawa, S.5
Sumazaki, R.6
Iizuka, T.7
Hosoda, Y.8
Okamoto, M.9
Murakami, J.10
-
98
-
-
77954356940
-
Histological findings in the livers of patients with neonatal intrahepatic cholestasis caused by citrin deficiency
-
Kimura, A., M. Kage, I. Nagata, S. Mushiake, T. Ohura, Y. Tazawa, S. Maisawa, T. Tomomasa, D. Abukawa, Y. Okano, et al. 2010. Histological findings in the livers of patients with neonatal intrahepatic cholestasis caused by citrin deficiency. Hepatol. Res. 40: 295-303.
-
(2010)
Hepatol. Res.
, vol.40
, pp. 295-303
-
-
Kimura, A.1
Kage, M.2
Nagata, I.3
Mushiake, S.4
Ohura, T.5
Tazawa, Y.6
Maisawa, S.7
Tomomasa, T.8
Abukawa, D.9
Okano, Y.10
-
99
-
-
0035005987
-
Possible clinical and histologic manifestations of adult-onset type II citrullinemia in early infancy
-
DOI 10.1067/mpd.2001.113361
-
Tomomasa, T., K. Kobayashi, H. Kaneko, H. Shimura, T. Fukusato, M. Tabata, Y. Inoue, S. Ohwada, M. Kasahara, Y. Morishita, et al. 2001. Possible clinical and histologic manifestations of adult-onset type II citrullinemia in early infancy. J. Pediatr. 138: 741-743. (Pubitemid 32417678)
-
(2001)
Journal of Pediatrics
, vol.138
, Issue.5
, pp. 741-743
-
-
Tomomasa, T.1
Kobayashi, K.2
Kaneko, H.3
Shimura, H.4
Fukusato, T.5
Tabata, M.6
Inoue, Y.7
Ohwada, S.8
Kasahara, M.9
Morishita, Y.10
Kimura, M.11
Saheki, T.12
Morikawa, A.13
-
100
-
-
34548148047
-
Thematic review series: Adipocyte Biology. Lipodystrophies: Windows on adipose biology and metabolism
-
Hegele, R. A., T. R. Joy, S. A. Al-Attar, and B. K. Rutt. 2007. Thematic review series: Adipocyte Biology. Lipodystrophies: windows on adipose biology and metabolism. J. Lipid Res. 48: 1433-1444.
-
(2007)
J. Lipid Res.
, vol.48
, pp. 1433-1444
-
-
Hegele, R.A.1
Joy, T.R.2
Al-Attar, S.A.3
Rutt, B.K.4
-
101
-
-
0037342243
-
A new clinical condition linked to a novel mutation in lamins A and C with generalized lipoatrophy, insulin-resistant diabetes, disseminated leukomelanodermic papules, liver steatosis, and cardiomyopathy
-
Caux, F., E. Dubosclard, O. Lascols, B. Buendia, O. Chazouilleres, A. Cohen, J. C. Courvalin, L. Laroche, J. Capeau, C. Vigouroux, et al. 2003. A new clinical condition linked to a novel mutation in lamins A and C with generalized lipoatrophy, insulin-resistant diabetes, disseminated leukomelanodermic papules, liver steatosis, and cardiomyopathy. J. Clin. Endocrinol. Metab. 88: 1006-1013.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 1006-1013
-
-
Caux, F.1
Dubosclard, E.2
Lascols, O.3
Buendia, B.4
Chazouilleres, O.5
Cohen, A.6
Courvalin, J.C.7
Laroche, L.8
Capeau, J.9
Vigouroux, C.10
-
102
-
-
0034059075
-
Nuclear lamin A/C R482Q mutation in canadian kindreds with Dunnigan-type familial partial lipodystrophy
-
Cao, H., and R. A. Hegele. 2000. Nuclear lamin A/C R482Q mutation in canadian kindreds with Dunnigan-type familial partial lipodystrophy. Hum. Mol. Genet. 9: 109-112.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 109-112
-
-
Cao, H.1
Hegele, R.A.2
-
103
-
-
68849119046
-
Laminopathies and the long strange trip from basic cell biology to therapy
-
Worman, H. J., L. G. Fong, A. Muchir, and S. G. Young. 2009. Laminopathies and the long strange trip from basic cell biology to therapy. J. Clin. Invest. 119: 1825-1836.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1825-1836
-
-
Worman, H.J.1
Fong, L.G.2
Muchir, A.3
Young, S.G.4
-
104
-
-
27744588049
-
Hepatic steatosis in Dunnigan-type familial partial lipodystrophy
-
Ludtke, A., J. Genschel, G. Brabant, J. Bauditz, M. Taupitz, M. Koch, W. Wermke, H. J. Worman, and H. H. Schmidt. 2005. Hepatic steatosis in Dunnigan-type familial partial lipodystrophy. Am. J. Gastroenterol. 100: 2218-2224.
-
(2005)
Am. J. Gastroenterol.
, vol.100
, pp. 2218-2224
-
-
Ludtke, A.1
Genschel, J.2
Brabant, G.3
Bauditz, J.4
Taupitz, M.5
Koch, M.6
Wermke, W.7
Worman, H.J.8
Schmidt, H.H.9
-
105
-
-
57349113235
-
Fatty acid metabolism in patients with PPARgamma mutations
-
Tan, G. D., D. B. Savage, B. A. Fielding, J. Collins, L. Hodson, S. M. Humphreys, S. O'Rahilly, K. Chatterjee, K. N. Frayn, and F. Karpe. 2008. Fatty acid metabolism in patients with PPARgamma mutations. J. Clin. Endocrinol. Metab. 93: 4462-4470.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 4462-4470
-
-
Tan, G.D.1
Savage, D.B.2
Fielding, B.A.3
Collins, J.4
Hodson, L.5
Humphreys, S.M.6
O'Rahilly, S.7
Chatterjee, K.8
Frayn, K.N.9
Karpe, F.10
-
106
-
-
9144229185
-
Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle
-
He, W., Y. Barak, A. Hevener, P. Olson, D. Liao, J. Le, M. Nelson, E. Ong, J. M. Olefsky, and R. M. Evans. 2003. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc. Natl. Acad. Sci. USA. 100: 15712-15717.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15712-15717
-
-
He, W.1
Barak, Y.2
Hevener, A.3
Olson, P.4
Liao, D.5
Le, J.6
Nelson, M.7
Ong, E.8
Olefsky, J.M.9
Evans, R.M.10
-
107
-
-
1842848578
-
Post-mortem findings in familial partial lipodystrophy, Dunnigan variety
-
Haque, W. A., F. Vuitch, and A. Garg. 2002. Post-mortem findings in familial partial lipodystrophy, Dunnigan variety. Diabet. Med. 19: 1022-1025.
-
(2002)
Diabet. Med.
, vol.19
, pp. 1022-1025
-
-
Haque, W.A.1
Vuitch, F.2
Garg, A.3
-
108
-
-
0036578783
-
AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34
-
Agarwal, A. K., E. Arioglu, S. De Almeida, N. Akkoc, S. I. Taylor, A. M. Bowcock, R. I. Barnes, and A. Garg. 2002. AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34. Nat. Genet. 31: 21-23.
-
(2002)
Nat. Genet.
, vol.31
, pp. 21-23
-
-
Agarwal, A.K.1
Arioglu, E.2
De Almeida, S.3
Akkoc, N.4
Taylor, S.I.5
Bowcock, A.M.6
Barnes, R.I.7
Garg, A.8
-
109
-
-
0038607416
-
Congenital generalized lipodystrophy: Significance of triglyceride biosynthetic pathways
-
Agarwal, A. K., and A. Garg. 2003. Congenital generalized lipodystrophy: significance of triglyceride biosynthetic pathways. Trends Endocrinol. Metab. 14: 214-221.
-
(2003)
Trends Endocrinol. Metab.
, vol.14
, pp. 214-221
-
-
Agarwal, A.K.1
Garg, A.2
-
110
-
-
67349228443
-
Lipodystrophies: Disorders of adipose tissue biology
-
Garg, A., and A. K. Agarwal. 2009. Lipodystrophies: disorders of adipose tissue biology. Biochim. Biophys. Acta. 1791: 507-513.
-
(2009)
Biochim. Biophys. Acta
, vol.1791
, pp. 507-513
-
-
Garg, A.1
Agarwal, A.K.2
-
111
-
-
77957221736
-
Central players in inherited lipodystrophies
-
Jeninga, E. H., and E. Kalkhoven. 2010. Central players in inherited lipodystrophies. Trends Endocrinol. Metab. 21: 581-588.
-
(2010)
Trends Endocrinol. Metab.
, vol.21
, pp. 581-588
-
-
Jeninga, E.H.1
Kalkhoven, E.2
-
112
-
-
33744954152
-
A regulatory role for 1-acylglycerol- 3-phosphate-O-acyltransferase 2 in adipocyte differentiation
-
Gale, S. E., A. Frolov, X. Han, P. E. Bickel, L. Cao, A. Bowcock, J. E. Schaffer, and D. S. Ory. 2006. A regulatory role for 1-acylglycerol- 3-phosphate-O-acyltransferase 2 in adipocyte differentiation. J. Biol. Chem. 281: 11082-11089.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 11082-11089
-
-
Gale, S.E.1
Frolov, A.2
Han, X.3
Bickel, P.E.4
Cao, L.5
Bowcock, A.6
Schaffer, J.E.7
Ory, D.S.8
-
113
-
-
58749091644
-
Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy
-
Cortes, V. A., D. E. Curtis, S. Sukumaran, X. Shao, V. Parameswara, S. Rashid, A. R. Smith, J. Ren, V. Esser, R. E. Hammer, et al. 2009. Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy. Cell Metab. 9: 165-176.
-
(2009)
Cell Metab.
, vol.9
, pp. 165-176
-
-
Cortes, V.A.1
Curtis, D.E.2
Sukumaran, S.3
Shao, X.4
Parameswara, V.5
Rashid, S.6
Smith, A.R.7
Ren, J.8
Esser, V.9
Hammer, R.E.10
-
114
-
-
18644371065
-
Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy
-
Van Maldergem, L., J. Magre, T. E. Khallouf, T. Gedde-Dahl, Jr., M. Delepine, O. Trygstad, E. Seemanova, T. Stephenson, C. S. Albott, F. Bonnici, et al. 2002. Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy. J. Med. Genet. 39: 722-733.
-
(2002)
J. Med. Genet.
, vol.39
, pp. 722-733
-
-
Van Maldergem, L.1
Magre, J.2
Khallouf, T.E.3
Gedde-Dahl Jr., T.4
Delepine, M.5
Trygstad, O.6
Seemanova, E.7
Stephenson, T.8
Albott, C.S.9
Bonnici, F.10
-
115
-
-
0034941121
-
Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13
-
Magre, J., M. Delepine, E. Khallouf, T. Gedde-Dahl, Jr., L. Van Maldergem, E. Sobel, J. Papp, M. Meier, A. Megarbane, A. Bachy, et al. 2001. Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13. Nat. Genet. 28: 365-370.
-
(2001)
Nat. Genet.
, vol.28
, pp. 365-370
-
-
Magre, J.1
Delepine, M.2
Khallouf, E.3
Gedde-Dahl Jr., T.4
Van Maldergem, L.5
Sobel, E.6
Papp, J.7
Meier, M.8
Megarbane, A.9
Bachy, A.10
-
116
-
-
50949112676
-
The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation
-
Payne, V. A., N. Grimsey, A. Tuthill, S. Virtue, S. L. Gray, E. Dalla Nora, R. K. Semple, S. O'Rahilly, and J. J. Rochford. 2008. The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation. Diabetes. 57: 2055-2060.
-
(2008)
Diabetes
, vol.57
, pp. 2055-2060
-
-
Payne, V.A.1
Grimsey, N.2
Tuthill, A.3
Virtue, S.4
Gray, S.L.5
Dalla Nora, E.6
Semple, R.K.7
O'Rahilly, S.8
Rochford, J.J.9
-
117
-
-
70349323186
-
The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation
-
Chen, W., V. K. Yechoor, B. H. Chang, M. V. Li, K. L. March, and L. Chan. 2009. The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation. Endocrinology. 150: 4552-4561.
-
(2009)
Endocrinology
, vol.150
, pp. 4552-4561
-
-
Chen, W.1
Yechoor, V.K.2
Chang, B.H.3
Li, M.V.4
March, K.L.5
Chan, L.6
-
118
-
-
33646462136
-
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
-
Haemmerle, G., A. Lass, R. Zimmermann, G. Gorkiewicz, C. Meyer, J. Rozman, G. Heldmaier, R. Maier, C. Theussl, S. Eder, et al. 2006. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science. 312: 734-737.
-
(2006)
Science
, vol.312
, pp. 734-737
-
-
Haemmerle, G.1
Lass, A.2
Zimmermann, R.3
Gorkiewicz, G.4
Meyer, C.5
Rozman, J.6
Heldmaier, G.7
Maier, R.8
Theussl, C.9
Eder, S.10
-
119
-
-
33646128723
-
Adipose triglyceride lipasemediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome
-
Lass, A., R. Zimmermann, G. Haemmerle, M. Riederer, G. Schoiswohl, M. Schweiger, P. Kienesberger, J. G. Strauss, G. Gorkiewicz, and R. Zechner. 2006. Adipose triglyceride lipasemediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metab. 3: 309-319.
-
(2006)
Cell Metab.
, vol.3
, pp. 309-319
-
-
Lass, A.1
Zimmermann, R.2
Haemmerle, G.3
Riederer, M.4
Schoiswohl, G.5
Schweiger, M.6
Kienesberger, P.7
Strauss, J.G.8
Gorkiewicz, G.9
Zechner, R.10
-
120
-
-
63449127032
-
Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores
-
Zechner, R., P. C. Kienesberger, G. Haemmerle, R. Zimmermann, and A. Lass. 2009. Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores. J. Lipid Res. 50: 3-21.
-
(2009)
J. Lipid Res.
, vol.50
, pp. 3-21
-
-
Zechner, R.1
Kienesberger, P.C.2
Haemmerle, G.3
Zimmermann, R.4
Lass, A.5
-
121
-
-
78149346457
-
CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance
-
Brown, J. M., J. L. Betters, C. Lord, Y. Ma, X. Han, K. Yang, H. M. Alger, J. Melchior, J. Sawyer, R. Shah, et al. 2010. CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance. J. Lipid Res. 51: 3306-3315.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 3306-3315
-
-
Brown, J.M.1
Betters, J.L.2
Lord, C.3
Ma, Y.4
Han, X.5
Yang, K.6
Alger, H.M.7
Melchior, J.8
Sawyer, J.9
Shah, R.10
-
122
-
-
68049092870
-
Neutral lipid storage disease: Genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5
-
Schweiger, M., A. Lass, R. Zimmermann, T. O. Eichmann, and R. Zechner. 2009. Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5. Am. J. Physiol. Endocrinol. Metab. 297: E289-E296.
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
-
-
Schweiger, M.1
Lass, A.2
Zimmermann, R.3
Eichmann, T.O.4
Zechner, R.5
-
123
-
-
37049010298
-
Novel duplication mutation in the patatin domain of adipose triglyceride lipase (PNPLA2) in neutral lipid storage disease with severe myopathy
-
DOI 10.1002/mus.20869
-
Akiyama, M., K. Sakai, M. Ogawa, J. R. McMillan, D. Sawamura, and H. Shimizu. 2007. Novel duplication mutation in the patatin domain of adipose triglyceride lipase (PNPLA2) in neutral lipid storage disease with severe myopathy. Muscle Nerve. 36: 856-859. (Pubitemid 350246936)
-
(2007)
Muscle and Nerve
, vol.36
, Issue.6
, pp. 856-859
-
-
Akiyama, M.1
Sakai, K.2
Ogawa, M.3
McMillan, J.R.4
Sawamura, D.5
Shimizu, H.6
-
124
-
-
47749132272
-
The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding
-
Schweiger, M., G. Schoiswohl, A. Lass, F. P. Radner, G. Haemmerle, R. Malli, W. Graier, I. Cornaciu, M. Oberer, R. Salvayre, et al. 2008. The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding. J. Biol. Chem. 283: 17211-17220.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 17211-17220
-
-
Schweiger, M.1
Schoiswohl, G.2
Lass, A.3
Radner, F.P.4
Haemmerle, G.5
Malli, R.6
Graier, W.7
Cornaciu, I.8
Oberer, M.9
Salvayre, R.10
-
125
-
-
51449092035
-
Wolman disease/ cholesteryl ester storage disease: Efficacy of plant-produced human lysosomal acid lipase in mice
-
Du, H., T. L. Cameron, S. J. Garger, G. P. Pogue, L. A. Hamm, E. White, K. M. Hanley, and G. A. Grabowski. 2008. Wolman disease/ cholesteryl ester storage disease: efficacy of plant-produced human lysosomal acid lipase in mice. J. Lipid Res. 49: 1646-1657.
-
(2008)
J. Lipid Res.
, vol.49
, pp. 1646-1657
-
-
Du, H.1
Cameron, T.L.2
Garger, S.J.3
Pogue, G.P.4
Hamm, L.A.5
White, E.6
Hanley, K.M.7
Grabowski, G.A.8
-
126
-
-
0029877616
-
Genetic and biochemical evidence that CESD and Wolman disease are distinguished by residual lysosomal acid lipase activity
-
DOI 10.1006/geno.1996.0162
-
Aslanidis, C., S. Ries, P. Fehringer, C. Buchler, H. Klima, and G. Schmitz. 1996. Genetic and biochemical evidence that CESD and Wolman disease are distinguished by residual lysosomal acid lipase activity. Genomics. 33: 85-93. (Pubitemid 26119398)
-
(1996)
Genomics
, vol.33
, Issue.1
, pp. 85-93
-
-
Aslanidis, C.1
Ries, S.2
Fehringer, P.3
Buchler, C.4
Klima, H.5
Schmitz, G.6
-
127
-
-
0033585476
-
Prevalence of lysosomal storage disorders
-
Meikle, P. J., J. J. Hopwood, A. E. Clague, and W. F. Carey. 1999. Prevalence of lysosomal storage disorders. JAMA. 281: 249-254.
-
(1999)
JAMA
, vol.281
, pp. 249-254
-
-
Meikle, P.J.1
Hopwood, J.J.2
Clague, A.E.3
Carey, W.F.4
-
128
-
-
84880985603
-
Combined hyperlipidaemia as a presenting sign of cholesteryl ester storage disease
-
Decarlis, S., C. Agostoni, F. Ferrante, S. Scarlino, E. Riva, and M. Giovannini. 2009. Combined hyperlipidaemia as a presenting sign of cholesteryl ester storage disease. J. Inherit. Metab. Dis.
-
(2009)
J. Inherit. Metab. Dis.
-
-
Decarlis, S.1
Agostoni, C.2
Ferrante, F.3
Scarlino, S.4
Riva, E.5
Giovannini, M.6
-
129
-
-
54049086492
-
A novel missense LIPA gene mutation, N98S, in a patient with cholesteryl ester storage disease
-
Hooper, A. J., H. A. Tran, M. R. Formby, and J. R. Burnett. 2008. A novel missense LIPA gene mutation, N98S, in a patient with cholesteryl ester storage disease. Clin. Chim. Acta. 398: 152-154.
-
(2008)
Clin. Chim. Acta
, vol.398
, pp. 152-154
-
-
Hooper, A.J.1
Tran, H.A.2
Formby, M.R.3
Burnett, J.R.4
-
130
-
-
0033995456
-
Accumulated lipids, aberrant fatty acid composition and defective cholesterol ester hydrolase activity in cholesterol ester storage disease
-
Todoroki, T., K. Matsumoto, K. Watanabe, Y. Tashiro, M. Shimizu, T. Okuyama, and K. Imai. 2000. Accumulated lipids, aberrant fatty acid composition and defective cholesterol ester hydrolase activity in cholesterol ester storage disease. Ann. Clin. Biochem. 37: 187-193.
-
(2000)
Ann. Clin. Biochem.
, vol.37
, pp. 187-193
-
-
Todoroki, T.1
Matsumoto, K.2
Watanabe, K.3
Tashiro, Y.4
Shimizu, M.5
Okuyama, T.6
Imai, K.7
-
131
-
-
0027131856
-
A splice junction mutation causes deletion of a 72-base exon from the mRNA for lysosomal acid lipase in a patient with cholesteryl ester storage disease
-
Klima, H., K. Ullrich, C. Aslanidis, P. Fehringer, K. J. Lackner, and G. Schmitz. 1993. A splice junction mutation causes deletion of a 72-base exon from the mRNA for lysosomal acid lipase in a patient with cholesteryl ester storage disease. J. Clin. Invest. 92: 2713-2718.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 2713-2718
-
-
Klima, H.1
Ullrich, K.2
Aslanidis, C.3
Fehringer, P.4
Lackner, K.J.5
Schmitz, G.6
-
132
-
-
34547636291
-
Prevalence of cholesteryl ester storage disease
-
Muntoni, S., H. Wiebusch, M. Jansen-Rust, S. Rust, U. Seedorf, H. Schulte, K. Berger, H. Funke, and G. Assmann. 2007. Prevalence of cholesteryl ester storage disease. Arterioscler. Thromb. Vasc. Biol. 27: 1866-1868.
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 1866-1868
-
-
Muntoni, S.1
Wiebusch, H.2
Jansen-Rust, M.3
Rust, S.4
Seedorf, U.5
Schulte, H.6
Berger, K.7
Funke, H.8
Assmann, G.9
-
133
-
-
0031852450
-
New lysosomal acid lipase gene mutants explain the phenotype of Wolman disease and cholesteryl ester storage disease
-
Pagani, F., R. Pariyarath, R. Garcia, C. Stuani, A. B. Burlina, G. Ruotolo, M. Rabusin, and F. E. Baralle. 1998. New lysosomal acid lipase gene mutants explain the phenotype of Wolman disease and cholesteryl ester storage disease. J. Lipid Res. 39: 1382-1388.
-
(1998)
J. Lipid Res.
, vol.39
, pp. 1382-1388
-
-
Pagani, F.1
Pariyarath, R.2
Garcia, R.3
Stuani, C.4
Burlina, A.B.5
Ruotolo, G.6
Rabusin, M.7
Baralle, F.E.8
-
134
-
-
0033004986
-
Recognition and management of fatty acid oxidation defects: A series of 107 patients
-
Saudubray, J. M., D. Martin, P. de Lonlay, G. Touati, F. Poggi- Travert, D. Bonnet, P. Jouvet, M. Boutron, A. Slama, C. Vianey-Saban, et al. 1999. Recognition and management of fatty acid oxidation defects: a series of 107 patients. J. Inherit. Metab. Dis. 22: 488-502.
-
(1999)
J. Inherit. Metab. Dis.
, vol.22
, pp. 488-502
-
-
Saudubray, J.M.1
Martin, D.2
De Lonlay, P.3
Touati, G.4
Poggi- Travert, F.5
Bonnet, D.6
Jouvet, P.7
Boutron, M.8
Slama, A.9
Vianey-Saban, C.10
-
135
-
-
36749082168
-
Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance
-
Zhang, D., Z. X. Liu, C. S. Choi, L. Tian, R. Kibbey, J. Dong, G. W. Cline, P. A. Wood, and G. I. Shulman. 2007. Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance. Proc. Natl. Acad. Sci. USA. 104: 17075-17080.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 17075-17080
-
-
Zhang, D.1
Liu, Z.X.2
Choi, C.S.3
Tian, L.4
Kibbey, R.5
Dong, J.6
Cline, G.W.7
Wood, P.A.8
Shulman, G.I.9
-
136
-
-
77955715392
-
Medium-chain triglycerides impair lipid metabolism and induce hepatic steatosis in very long-chain acyl-CoA dehydrogenase (VLCAD)-deficient mice
-
Tucci, S., S. Primassin, F. Ter Veld, and U. Spiekerkoetter. 2010. Medium-chain triglycerides impair lipid metabolism and induce hepatic steatosis in very long-chain acyl-CoA dehydrogenase (VLCAD)-deficient mice. Mol. Genet. Metab. 101: 40-47.
-
(2010)
Mol. Genet. Metab.
, vol.101
, pp. 40-47
-
-
Tucci, S.1
Primassin, S.2
Ter Veld, F.3
Spiekerkoetter, U.4
-
137
-
-
0033519714
-
A fetal fatty-acid oxidation disorder as a cause of liver disease in pregnant women
-
Ibdah, J. A., M. J. Bennett, P. Rinaldo, Y. Zhao, B. Gibson, H. F. Sims, and A. W. Strauss. 1999. A fetal fatty-acid oxidation disorder as a cause of liver disease in pregnant women. N. Engl. J. Med. 340: 1723-1731.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1723-1731
-
-
Ibdah, J.A.1
Bennett, M.J.2
Rinaldo, P.3
Zhao, Y.4
Gibson, B.5
Sims, H.F.6
Strauss, A.W.7
-
140
-
-
33845885117
-
Acute fatty liver of pregnancy: An update on pathogenesis and clinical implications
-
Ibdah, J. A. 2006. Acute fatty liver of pregnancy: an update on pathogenesis and clinical implications. World J. Gastroenterol. 12: 7397-7404.
-
(2006)
World J. Gastroenterol.
, vol.12
, pp. 7397-7404
-
-
Ibdah, J.A.1
-
141
-
-
33845267762
-
Effects of higher dietary protein intake on energy balance and metabolic control in children with longchain 3-hydroxy acyl-CoA dehydrogenase (LCHAD) or trifunctional protein (TFP) deficiency
-
Gillingham, M. B., J. Q. Purnell, J. Jordan, D. Stadler, A. M. Haqq, and C. O. Harding. 2007. Effects of higher dietary protein intake on energy balance and metabolic control in children with longchain 3-hydroxy acyl-CoA dehydrogenase (LCHAD) or trifunctional protein (TFP) deficiency. Mol. Genet. Metab. 90: 64-69.
-
(2007)
Mol. Genet. Metab.
, vol.90
, pp. 64-69
-
-
Gillingham, M.B.1
Purnell, J.Q.2
Jordan, J.3
Stadler, D.4
Haqq, A.M.5
Harding, C.O.6
-
142
-
-
61749100743
-
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis
-
Semple, R. K., A. Sleigh, P. R. Murgatroyd, C. A. Adams, L. Bluck, S. Jackson, A. Vottero, D. Kanabar, V. Charlton-Menys, P. Durrington, et al. 2009.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 315-322
-
-
Semple, R.K.1
Sleigh, A.2
Murgatroyd, P.R.3
Adams, C.A.4
Bluck, L.5
Jackson, S.6
Vottero, A.7
Kanabar, D.8
Charlton-Menys, V.9
Durrington, P.10
-
143
-
-
2542528670
-
A family with severe insulin resistance and diabetes due to a mutation in AKT2
-
DOI 10.1126/science.1096706
-
George, S., J. J. Rochford, C. Wolfrum, S. L. Gray, S. Schinner, J. C. Wilson, M. A. Soos, P. R. Murgatroyd, R. M. Williams, C. L. Acerini, et al. 2004. A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science. 304: 1325-1328. (Pubitemid 38697429)
-
(2004)
Science
, vol.304
, Issue.5675
, pp. 1325-1328
-
-
George, S.1
Rochford, J.J.2
Wolfrum, C.3
Gray, S.L.4
Schinner, S.5
Wilson, J.C.6
Soos, M.A.7
Murgatroyd, P.R.8
Williams, R.M.9
Acerini, C.L.10
Dunger, D.B.11
Barford, D.12
Umpleby, A.M.13
Wareham, N.J.14
Davies, H.A.15
Schafer, A.J.16
Stoffel, M.17
O'Rahilly, S.18
Barroso, I.19
-
144
-
-
56749096610
-
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
-
Romeo, S., J. Kozlitina, C. Xing, A. Pertsemlidis, D. Cox, L. A. Pennacchio, E. Boerwinkle, J. C. Cohen, and H. H. Hobbs. 2008. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat. Genet. 40: 1461-1465.
-
(2008)
Nat. Genet.
, vol.40
, pp. 1461-1465
-
-
Romeo, S.1
Kozlitina, J.2
Xing, C.3
Pertsemlidis, A.4
Cox, D.5
Pennacchio, L.A.6
Boerwinkle, E.7
Cohen, J.C.8
Hobbs, H.H.9
-
145
-
-
0035823621
-
Adiponutrin, a transmembrane protein corresponding to a novel dietary-and obesity-linked mRNA specifically expressed in the adipose lineage
-
Baulande, S., F. Lasnier, M. Lucas, and J. Pairault. 2001. Adiponutrin, a transmembrane protein corresponding to a novel dietary-and obesity-linked mRNA specifically expressed in the adipose lineage. J. Biol. Chem. 276: 33336-33344.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33336-33344
-
-
Baulande, S.1
Lasnier, F.2
Lucas, M.3
Pairault, J.4
-
146
-
-
33748745960
-
Characterization of the human patatin-like phospholipase family
-
Wilson, P. A., S. D. Gardner, N. M. Lambie, S. A. Commans, and D. J. Crowther. 2006. Characterization of the human patatin-like phospholipase family. J. Lipid Res. 47: 1940-1949.
-
(2006)
J. Lipid Res.
, vol.47
, pp. 1940-1949
-
-
Wilson, P.A.1
Gardner, S.D.2
Lambie, N.M.3
Commans, S.A.4
Crowther, D.J.5
-
147
-
-
77952352488
-
Unravelling the pathogenesis of fatty liver disease: Patatin-like phospholipase domain-containing 3 protein
-
Romeo, S., I. Huang-Doran, M. G. Baroni, and A. Kotronen. 2010. Unravelling the pathogenesis of fatty liver disease: patatin-like phospholipase domain-containing 3 protein. Curr. Opin. Lipidol. 21: 247-252.
-
(2010)
Curr. Opin. Lipidol.
, vol.21
, pp. 247-252
-
-
Romeo, S.1
Huang-Doran, I.2
Baroni, M.G.3
Kotronen, A.4
-
148
-
-
77952409634
-
A feed-forward loop amplifies nutritional regulation of PNPLA3
-
Huang, Y., S. He, J. Z. Li, Y. K. Seo, T. F. Osborne, J. C. Cohen, and H. H. Hobbs. 2010. A feed-forward loop amplifies nutritional regulation of PNPLA3. Proc. Natl. Acad. Sci. USA. 107: 7892-7897.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 7892-7897
-
-
Huang, Y.1
He, S.2
Li, J.Z.3
Seo, Y.K.4
Osborne, T.F.5
Cohen, J.C.6
Hobbs, H.H.7
-
149
-
-
77956625538
-
Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease
-
Chen, W., B. Chang, L. Li, and L. Chan. 2010. Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease. Hepatology. 52: 1134-1142.
-
(2010)
Hepatology
, vol.52
, pp. 1134-1142
-
-
Chen, W.1
Chang, B.2
Li, L.3
Chan, L.4
-
150
-
-
34347235098
-
Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver
-
DOI 10.1016/j.cmet.2007.05.005, PII S1550413107001325
-
Monetti, M., M. C. Levin, M. J. Watt, M. P. Sajan, S. Marmor, B. K. Hubbard, R. D. Stevens, J. R. Bain, C. B. Newgard, R. V. Farese, Sr., et al. 2007. Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metab. 6: 69-78. (Pubitemid 46995777)
-
(2007)
Cell Metabolism
, vol.6
, Issue.1
, pp. 69-78
-
-
Monetti, M.1
Levin, M.C.2
Watt, M.J.3
Sajan, M.P.4
Marmor, S.5
Hubbard, B.K.6
Stevens, R.D.7
Bain, J.R.8
Newgard, C.B.9
Farese Sr., R.V.10
Hevener, A.L.11
Farese Jr., R.V.12
-
151
-
-
67349174005
-
A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans
-
Kotronen, A., L. E. Johansson, L. M. Johansson, C. Roos, J. Westerbacka, A. Hamsten, R. Bergholm, P. Arkkila, J. Arola, T. Kiviluoto, et al. 2009. A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans. Diabetologia. 52: 1056-1060.
-
(2009)
Diabetologia
, vol.52
, pp. 1056-1060
-
-
Kotronen, A.1
Johansson, L.E.2
Johansson, L.M.3
Roos, C.4
Westerbacka, J.5
Hamsten, A.6
Bergholm, R.7
Arkkila, P.8
Arola, J.9
Kiviluoto, T.10
-
152
-
-
70350550096
-
Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene
-
Kantartzis, K., A. Peter, F. Machicao, J. Machann, S. Wagner, I. Konigsrainer, A. Konigsrainer, F. Schick, A. Fritsche, H. U. Haring, et al. 2009. Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene. Diabetes. 58: 2616-2623.
-
(2009)
Diabetes
, vol.58
, pp. 2616-2623
-
-
Kantartzis, K.1
Peter, A.2
Machicao, F.3
Machann, J.4
Wagner, S.5
Konigsrainer, I.6
Konigsrainer, A.7
Schick, F.8
Fritsche, A.9
Haring, H.U.10
-
153
-
-
77957970113
-
A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents
-
Santoro, N., R. Kursawe, E. D'Adamo, D. J. Dykas, C. K. Zhang, A. E. Bale, A. M. Cali, D. Narayan, M. M. Shaw, B. Pierpont, et al. 2010. A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents. Hepatology. 52: 1281-1290.
-
(2010)
Hepatology
, vol.52
, pp. 1281-1290
-
-
Santoro, N.1
Kursawe, R.2
D'Adamo, E.3
Dykas, D.J.4
Zhang, C.K.5
Bale, A.E.6
Cali, A.M.7
Narayan, D.8
Shaw, M.M.9
Pierpont, B.10
-
154
-
-
78650054891
-
Specifically PNPLA3-mediated accumulation of liver fat in obese patients with type 2 diabetes
-
Petit, J. M., B. Guiu, D. Masson, L. Duvillard, V. Jooste, P. Buffier, B. Terriat, B. Bouillet, M. C. Brindisi, et al. 2010. Specifically PNPLA3-mediated accumulation of liver fat in obese patients with type 2 diabetes. J. Clin. Endocrinol. Metab. 95: E430-E436.
-
(2010)
J. Clin. Endocrinol. Metab.
, vol.95
-
-
Petit, J.M.1
Guiu, B.2
Masson, D.3
Duvillard, L.4
Jooste, V.5
Buffier, P.6
Terriat, B.7
Bouillet, B.8
Brindisi, M.C.9
-
155
-
-
77349106712
-
A common variant in the adiponutrin gene influences liver enzyme levels
-
Kollerits, B., S. Coassin, S. Kiechl, S. C. Hunt, B. Paulweber, J. Willeit, A. Brandstatter, T. D. Adams, and F. Kronenberg. 2010. A common variant in the adiponutrin gene influences liver enzyme levels. J. Med. Genet. 47: 116-119.
-
(2010)
J. Med. Genet.
, vol.47
, pp. 116-119
-
-
Kollerits, B.1
Coassin, S.2
Kiechl, S.3
Hunt, S.C.4
Paulweber, B.5
Willeit, J.6
Brandstatter, A.7
Adams, T.D.8
Kronenberg, F.9
-
156
-
-
70449403261
-
Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins
-
Kollerits, B., S. Coassin, N. D. Beckmann, A. Teumer, S. Kiechl, A. Doring, M. Kavousi, S. C. Hunt, C. Lamina, B. Paulweber, et al. 2009. Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins. Hum. Mol. Genet. 18: 4669-4676.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4669-4676
-
-
Kollerits, B.1
Coassin, S.2
Beckmann, N.D.3
Teumer, A.4
Kiechl, S.5
Doring, A.6
Kavousi, M.7
Hunt, S.C.8
Lamina, C.9
Paulweber, B.10
-
157
-
-
33644778830
-
Variation in the adiponutrin gene influences its expression and associates with obesity
-
Johansson, L. E., J. Hoffstedt, H. Parikh, E. Carlsson, M. Wabitsch, A. G. Bondeson, J. Hedenbro, H. Tornqvist, L. Groop, and M. Ridderstrale. 2006. Variation in the adiponutrin gene influences its expression and associates with obesity. Diabetes. 55: 826-833. (Pubitemid 43343243)
-
(2006)
Diabetes
, vol.55
, Issue.3
, pp. 826-833
-
-
Johansson, L.E.1
Hoffstedt, J.2
Parikh, H.3
Carlsson, E.4
Wabitsch, M.5
Bondeson, A.-G.6
Hedenbro, J.7
Tornqvist, H.8
Groop, L.9
Ridderstrale, M.10
-
158
-
-
69249111667
-
A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity
-
Sookoian, S., G. O. Castano, A. L. Burgueno, T. F. Gianotti, M. S. Rosselli, and C. J. Pirola. 2009. A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity. J. Lipid Res. 50: 2111-2116.
-
(2009)
J. Lipid Res.
, vol.50
, pp. 2111-2116
-
-
Sookoian, S.1
Castano, G.O.2
Burgueno, A.L.3
Gianotti, T.F.4
Rosselli, M.S.5
Pirola, C.J.6
-
159
-
-
77956636268
-
The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease
-
Rotman, Y., C. Koh, J. M. Zmuda, D. E. Kleiner, and T. J. Liang. 2010. The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. Hepatology. 52: 894-903.
-
(2010)
Hepatology
, vol.52
, pp. 894-903
-
-
Rotman, Y.1
Koh, C.2
Zmuda, J.M.3
Kleiner, D.E.4
Liang, T.J.5
-
160
-
-
77957936457
-
I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease
-
Valenti, L., A. Alisi, E. Galmozzi, A. Bartuli, B. Del Menico, A. Alterio, P. Dongiovanni, S. Fargion, and V. Nobili. 2010. I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease. Hepatology. 52: 1274-1280.
-
(2010)
Hepatology
, vol.52
, pp. 1274-1280
-
-
Valenti, L.1
Alisi, A.2
Galmozzi, E.3
Bartuli, A.4
Del Menico, B.5
Alterio, A.6
Dongiovanni, P.7
Fargion, S.8
Nobili, V.9
-
161
-
-
73349111259
-
Variant in PNPLA3 is associated with alcoholic liver disease
-
Tian, C., R. P. Stokowski, D. Kershenobich, D. G. Ballinger, and D. A. Hinds. 2010. Variant in PNPLA3 is associated with alcoholic liver disease. Nat. Genet. 42: 21-23.
-
(2010)
Nat. Genet.
, vol.42
, pp. 21-23
-
-
Tian, C.1
Stokowski, R.P.2
Kershenobich, D.3
Ballinger, D.G.4
Hinds, D.A.5
-
162
-
-
77950607738
-
Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease
-
Valenti, L., A. Al-Serri, A. K. Daly, E. Galmozzi, R. Rametta, P. Dongiovanni, V. Nobili, E. Mozzi, G. Roviaro, E. Vanni, et al. 2010. Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology. 51: 1209-1217.
-
(2010)
Hepatology
, vol.51
, pp. 1209-1217
-
-
Valenti, L.1
Al-Serri, A.2
Daly, A.K.3
Galmozzi, E.4
Rametta, R.5
Dongiovanni, P.6
Nobili, V.7
Mozzi, E.8
Roviaro, G.9
Vanni, E.10
-
163
-
-
74249093842
-
Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent
-
Romeo, S., F. Sentinelli, S. Dash, G. S. Yeo, D. B. Savage, F. Leonetti, D. Capoccia, M. Incani, C. Maglio, et al. 2010. Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent. Int. J. Obes. (Lond.). 34: 190-194.
-
(2010)
Int. J. Obes. (Lond.)
, vol.34
, pp. 190-194
-
-
Romeo, S.1
Sentinelli, F.2
Dash, S.3
Yeo, G.S.4
Savage, D.B.5
Leonetti, F.6
Capoccia, D.7
Incani, M.8
Maglio, C.9
-
164
-
-
10344262633
-
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
-
Jenkins, C. M., D. J. Mancuso, W. Yan, H. F. Sims, B. Gibson, and R. W. Gross. 2004. Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. J. Biol. Chem. 279: 48968-48975.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 48968-48975
-
-
Jenkins, C.M.1
Mancuso, D.J.2
Yan, W.3
Sims, H.F.4
Gibson, B.5
Gross, R.W.6
-
165
-
-
33644764922
-
Adipose triglyceride lipase: Function, regulation by insulin, and comparison with adiponutrin
-
Kershaw, E. E., J. K. Hamm, L. A. Verhagen, O. Peroni, M. Katic, and J. S. Flier. 2006. Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin. Diabetes. 55: 148-157.
-
(2006)
Diabetes
, vol.55
, pp. 148-157
-
-
Kershaw, E.E.1
Hamm, J.K.2
Verhagen, L.A.3
Peroni, O.4
Katic, M.5
Flier, J.S.6
-
166
-
-
27444433258
-
Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members
-
DOI 10.1194/jlr.M500290-JLR200
-
Lake, A. C., Y. Sun, J. L. Li, J. E. Kim, J. W. Johnson, D. Li, T. Revett, H. H. Shih, W. Liu, J. E. Paulsen, et al. 2005. Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members. J. Lipid Res. 46: 2477-2487. (Pubitemid 41532536)
-
(2005)
Journal of Lipid Research
, vol.46
, Issue.11
, pp. 2477-2487
-
-
Lake, A.C.1
Sun, Y.2
Li, J.-L.3
Kim, J.E.4
Johnson, J.W.5
Li, D.6
Revett, T.7
Shih, H.H.8
Liu, W.9
Paulsen, J.E.10
Gimeno, R.E.11
-
167
-
-
77949895032
-
A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis
-
He, S., C. McPhaul, J. Z. Li, R. Garuti, L. Kinch, N. V. Grishin, J. C. Cohen, and H. H. Hobbs. 2010. A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J. Biol. Chem. 285: 6706-6715.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6706-6715
-
-
He, S.1
McPhaul, C.2
Li, J.Z.3
Garuti, R.4
Kinch, L.5
Grishin, N.V.6
Cohen, J.C.7
Hobbs, H.H.8
-
168
-
-
33749064375
-
Adiponutrin gene is regulated by insulin and glucose in human adipose tissue
-
Moldes, M., G. Beauregard, M. Faraj, N. Peretti, P. H. Ducluzeau, M. Laville, R. Rabasa-Lhoret, H. Vidal, and K. Clement. 2006. Adiponutrin gene is regulated by insulin and glucose in human adipose tissue. Eur. J. Endocrinol. 155: 461-468.
-
(2006)
Eur. J. Endocrinol.
, vol.155
, pp. 461-468
-
-
Moldes, M.1
Beauregard, G.2
Faraj, M.3
Peretti, N.4
Ducluzeau, P.H.5
Laville, M.6
Rabasa-Lhoret, R.7
Vidal, H.8
Clement, K.9
-
169
-
-
2942653172
-
Adiponutrin: A new gene regulated by energy balance in human adipose tissue
-
Liu, Y. M., M. Moldes, J. P. Bastard, E. Bruckert, N. Viguerie, B. Hainque, A. Basdevant, D. Langin, J. Pairault, and K. Clement. 2004. Adiponutrin: a new gene regulated by energy balance in human adipose tissue. J. Clin. Endocrinol. Metab. 89: 2684-2689.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 2684-2689
-
-
Liu, Y.M.1
Moldes, M.2
Bastard, J.P.3
Bruckert, E.4
Viguerie, N.5
Hainque, B.6
Basdevant, A.7
Langin, D.8
Pairault, J.9
Clement, K.10
-
170
-
-
55749101261
-
Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity
-
Johansson, L. E., U. Lindblad, C. A. Larsson, L. Rastam, and M. Ridderstrale. 2008. Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity. Eur. J. Endocrinol. 159: 577-583.
-
(2008)
Eur. J. Endocrinol.
, vol.159
, pp. 577-583
-
-
Johansson, L.E.1
Lindblad, U.2
Larsson, C.A.3
Rastam, L.4
Ridderstrale, M.5
-
171
-
-
53049090077
-
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes
-
Yuan, X., D. Waterworth, J. R. Perry, N. Lim, K. Song, J. C. Chambers, W. Zhang, P. Vollenweider, H. Stirnadel, T. Johnson, et al. 2008. Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am. J. Hum. Genet. 83: 520-528.
-
(2008)
Am. J. Hum. Genet.
, vol.83
, pp. 520-528
-
-
Yuan, X.1
Waterworth, D.2
Perry, J.R.3
Lim, N.4
Song, K.5
Chambers, J.C.6
Zhang, W.7
Vollenweider, P.8
Stirnadel, H.9
Johnson, T.10
-
172
-
-
77950202777
-
Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease
-
Petersen, K. F., S. Dufour, A. Hariri, C. Nelson-Williams, J. N. Foo, X. M. Zhang, J. Dziura, R. P. Lifton, and G. I. Shulman. 2010. Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease. N. Engl. J. Med. 362: 1082-1089.
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 1082-1089
-
-
Petersen, K.F.1
Dufour, S.2
Hariri, A.3
Nelson-Williams, C.4
Foo, J.N.5
Zhang, X.M.6
Dziura, J.7
Lifton, R.P.8
Shulman, G.I.9
-
173
-
-
0037244002
-
Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly
-
DOI 10.1194/jlr.R200014-JLR200
-
Hussain, M. M., J. Shi, and P. Dreizen. 2003. Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly. J. Lipid Res. 44: 22-32. (Pubitemid 36114766)
-
(2003)
Journal of Lipid Research
, vol.44
, Issue.1
, pp. 22-32
-
-
Hussain, M.M.1
Shi, J.2
Dreizen, P.3
-
174
-
-
70349249503
-
Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis
-
Fujita, K., Y. Nozaki, K. Wada, M. Yoneda, Y. Fujimoto, M. Fujitake, H. Endo, H. Takahashi, M. Inamori, N. Kobayashi, et al. 2009. Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis. Hepatology. 50: 772-780.
-
(2009)
Hepatology
, vol.50
, pp. 772-780
-
-
Fujita, K.1
Nozaki, Y.2
Wada, K.3
Yoneda, M.4
Fujimoto, Y.5
Fujitake, M.6
Endo, H.7
Takahashi, H.8
Inamori, M.9
Kobayashi, N.10
-
175
-
-
18244365866
-
Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: A model of viral-related steatosis
-
DOI 10.1096/fj.01-0396com
-
Perlemuter, G., A. Sabile, P. Letteron, G. Vona, A. Topilco, Y. Chretien, K. Koike, D. Pessayre, J. Chapman, G. Barba, et al. 2002. Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. FASEB J. 16: 185-194. (Pubitemid 34113012)
-
(2002)
FASEB Journal
, vol.16
, Issue.2
, pp. 185-194
-
-
Perlemuter, G.1
Sabile, A.2
Letteron, P.3
Vona, G.4
Topilco, A.5
Chretien, Y.6
Koike, K.7
Pessayre, D.8
Chapman, J.9
Barba, G.10
Brechot, C.11
-
176
-
-
0037732910
-
Hepatitis C virus-associated hypobetalipoproteinemia is correlated with plasma viral load, steatosis, and liver fibrosis
-
Petit, J. M., M. Benichou, L. Duvillard, V. Jooste, J. B. Bour, A. Minello, B. Verges, J. M. Brun, P. Gambert, and P. Hillon. 2003. Hepatitis C virus-associated hypobetalipoproteinemia is correlated with plasma viral load, steatosis, and liver fibrosis. Am. J. Gastroenterol. 98: 1150-1154.
-
(2003)
Am. J. Gastroenterol.
, vol.98
, pp. 1150-1154
-
-
Petit, J.M.1
Benichou, M.2
Duvillard, L.3
Jooste, V.4
Bour, J.B.5
Minello, A.6
Verges, B.7
Brun, J.M.8
Gambert, P.9
Hillon, P.10
-
177
-
-
0033846558
-
Association between microsomal triglyceride transfer protein gene polymorphism and the biological features of liver steatosis in patients with Type II diabetes
-
DOI 10.1007/s001250051481
-
Bernard, S., S. Touzet, I. Personne, V. Lapras, P. J. Bondon, F. Berthezene, and P. Moulin. 2000. Association between microsomal triglyceride transfer protein gene polymorphism and the biological features of liver steatosis in patients with type II diabetes. Diabetologia. 43: 995-999. (Pubitemid 30655718)
-
(2000)
Diabetologia
, vol.43
, Issue.8
, pp. 995-999
-
-
Bernard, S.1
Touzet, S.2
Personne, I.3
Lapras, V.4
Bondon, P.J.5
Berthezene, F.6
Moulin, P.7
-
178
-
-
11144356355
-
Polymorphisms of microsomal triglyceride transfer protein gene and manganese superoxide dismutase gene in non-alcoholic steatohepatitis
-
DOI 10.1016/j.jhep.2004.01.028, PII S0168827804000881
-
Namikawa, C., Z. Shu-Ping, J. R. Vyselaar, Y. Nozaki, Y. Nemoto, M. Ono, N. Akisawa, T. Saibara, M. Hiroi, H. Enzan, et al. 2004. Polymorphisms of microsomal triglyceride transfer protein gene and manganese superoxide dismutase gene in non-alcoholic steatohepatitis. J. Hepatol. 40: 781-786. (Pubitemid 38507358)
-
(2004)
Journal of Hepatology
, vol.40
, Issue.5
, pp. 781-786
-
-
Namikawa, C.1
Shu-Ping, Z.2
Vyselaar, J.R.3
Nozaki, Y.4
Nemoto, Y.5
Ono, M.6
Akisawa, N.7
Saibara, T.8
Hiroi, M.9
Enzan, H.10
Onishi, S.11
-
179
-
-
77649312075
-
Hepatic steatosis in hepatitis C is a storage disease due to HCV interaction with microsomal triglyceride transfer protein (MTP)
-
Mirandola, S., D. Bowman, M. M. Hussain, and A. Alberti. 2010. Hepatic steatosis in hepatitis C is a storage disease due to HCV interaction with microsomal triglyceride transfer protein (MTP). Nutr. Metab. (Lond.). 7: 13.
-
(2010)
Nutr. Metab. (Lond.)
, vol.7
, pp. 13
-
-
Mirandola, S.1
Bowman, D.2
Hussain, M.M.3
Alberti, A.4
-
180
-
-
52149104233
-
Microsomal triglyceride transfer protein (MTP)-493G/T gene polymorphism contributes to fat liver accumulation in HCV genotype 3 infected patients
-
Zampino, R., D. Ingrosso, E. Durante-Mangoni, R. Capasso, M. F. Tripodi, L. Restivo, V. Zappia, G. Ruggiero, and L. E. Adinolfi. 2008. Microsomal triglyceride transfer protein (MTP)-493G/T gene polymorphism contributes to fat liver accumulation in HCV genotype 3 infected patients. J. Viral Hepat. 15: 740-746.
-
(2008)
J. Viral Hepat.
, vol.15
, pp. 740-746
-
-
Zampino, R.1
Ingrosso, D.2
Durante-Mangoni, E.3
Capasso, R.4
Tripodi, M.F.5
Restivo, L.6
Zappia, V.7
Ruggiero, G.8
Adinolfi, L.E.9
-
181
-
-
62749100684
-
Microsomal triglyceride transfer protein polymorphism (-493G/T) is associated with hepatic steatosis in patients with chronic hepatitis C
-
Mirandola, S., C. H. Osterreicher, M. Marcolongo, C. Datz, E. Aigner, A. Schlabrakowski, S. Realdon, M. Gerotto, A. Alberti, and F. Stickel. 2009. Microsomal triglyceride transfer protein polymorphism (-493G/T) is associated with hepatic steatosis in patients with chronic hepatitis C. Liver Int. 29: 557-565.
-
(2009)
Liver Int.
, vol.29
, pp. 557-565
-
-
Mirandola, S.1
Osterreicher, C.H.2
Marcolongo, M.3
Datz, C.4
Aigner, E.5
Schlabrakowski, A.6
Realdon, S.7
Gerotto, M.8
Alberti, A.9
Stickel, F.10
-
182
-
-
77955845052
-
Lipoprotein metabolism mediates the association of MTP polymorphism with beta-cell dysfunction in healthy subjects and in nondiabetic normolipidemic patients with nonalcoholic steatohepatitis
-
Musso, G., R. Gambino, and M. Cassader. 2010. Lipoprotein metabolism mediates the association of MTP polymorphism with beta-cell dysfunction in healthy subjects and in nondiabetic normolipidemic patients with nonalcoholic steatohepatitis. J. Nutr. Biochem. 21: 834-840.
-
(2010)
J. Nutr. Biochem.
, vol.21
, pp. 834-840
-
-
Musso, G.1
Gambino, R.2
Cassader, M.3
-
183
-
-
34248657027
-
Polymorphism in microsomal triglyceride transfer protein: A link between liver disease and atherogenic postprandial lipid profile in NASH?
-
Gambino, R., M. Cassader, G. Pagano, M. Durazzo, and G. Musso. 2007. Polymorphism in microsomal triglyceride transfer protein: a link between liver disease and atherogenic postprandial lipid profile in NASH? Hepatology. 45: 1097-1107.
-
(2007)
Hepatology
, vol.45
, pp. 1097-1107
-
-
Gambino, R.1
Cassader, M.2
Pagano, G.3
Durazzo, M.4
Musso, G.5
-
184
-
-
2942746793
-
The role of acyl- CoA: Diacylglycerol acyltransferase (DGAT) in energy metabolism
-
Yu, Y. H., and H. N. Ginsberg. 2004. The role of acyl- CoA: diacylglycerol acyltransferase (DGAT) in energy metabolism. Ann. Med. 36: 252-261.
-
(2004)
Ann. Med.
, vol.36
, pp. 252-261
-
-
Yu, Y.H.1
Ginsberg, H.N.2
-
185
-
-
33845582410
-
Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production
-
Millar, J. S., S. J. Stone, U. J. Tietge, B. Tow, J. T. Billheimer, J. S. Wong, R. L. Hamilton, R. V. Farese, Jr., and D. J. Rader. 2006. Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production. J. Lipid Res. 47: 2297-2305.
-
(2006)
J. Lipid Res.
, vol.47
, pp. 2297-2305
-
-
Millar, J.S.1
Stone, S.J.2
Tietge, U.J.3
Tow, B.4
Billheimer, J.T.5
Wong, J.S.6
Hamilton, R.L.7
Farese Jr., R.V.8
Rader, D.J.9
-
186
-
-
23044450772
-
Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice
-
Yu, X. X., S. F. Murray, S. K. Pandey, S. L. Booten, D. Bao, X. Z. Song, S. Kelly, S. Chen, R. McKay, B. P. Monia, et al. 2005. Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice. Hepatology. 42: 362-371.
-
(2005)
Hepatology
, vol.42
, pp. 362-371
-
-
Yu, X.X.1
Murray, S.F.2
Pandey, S.K.3
Booten, S.L.4
Bao, D.5
Song, X.Z.6
Kelly, S.7
Chen, S.8
McKay, R.9
Monia, B.P.10
-
187
-
-
65549151428
-
The DGAT2 gene is a candidate for the dissociation between fatty liver and insulin resistance in humans
-
Kantartzis, K., F. Machicao, J. Machann, F. Schick, A. Fritsche, H. U. Haring, and N. Stefan. 2009. The DGAT2 gene is a candidate for the dissociation between fatty liver and insulin resistance in humans. Clin. Sci. (Lond.). 116: 531-537.
-
(2009)
Clin. Sci. (Lond.)
, vol.116
, pp. 531-537
-
-
Kantartzis, K.1
Machicao, F.2
Machann, J.3
Schick, F.4
Fritsche, A.5
Haring, H.U.6
Stefan, N.7
-
188
-
-
34249652929
-
Mutation screen and association studies in the diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13
-
Friedel, S., K. Reichwald, A. Scherag, H. Brumm, A. K. Wermter, H. R. Fries, K. Koberwitz, M. Wabitsch, T. Meitinger, M. Platzer, et al. 2007. Mutation screen and association studies in the diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13. BMC Genet. 8: 17.
-
(2007)
BMC Genet.
, vol.8
, pp. 17
-
-
Friedel, S.1
Reichwald, K.2
Scherag, A.3
Brumm, H.4
Wermter, A.K.5
Fries, H.R.6
Koberwitz, K.7
Wabitsch, M.8
Meitinger, T.9
Platzer, M.10
-
189
-
-
0037186623
-
Kinetic analyses of liver phosphatidylcholine and phosphatidylethanolamine biosynthesis using (13)C NMR spectroscopy
-
Reo, N. V., M. Adinehzadeh, and B. D. Foy. 2002. Kinetic analyses of liver phosphatidylcholine and phosphatidylethanolamine biosynthesis using (13)C NMR spectroscopy. Biochim. Biophys. Acta. 1580: 171-188.
-
(2002)
Biochim. Biophys. Acta
, vol.1580
, pp. 171-188
-
-
Reo, N.V.1
Adinehzadeh, M.2
Foy, B.D.3
-
190
-
-
0031552936
-
Phosphatidylethanolamine N-methyltransferase from liver
-
Vance, D. E., C. J. Walkey, and Z. Cui. 1997. Phosphatidylethanolamine N-methyltransferase from liver. Biochim. Biophys. Acta. 1348: 142-150.
-
(1997)
Biochim. Biophys. Acta
, vol.1348
, pp. 142-150
-
-
Vance, D.E.1
Walkey, C.J.2
Cui, Z.3
-
191
-
-
0023833533
-
The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes
-
Yao, Z. M., and D. E. Vance. 1988. The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes. J. Biol. Chem. 263: 2998-3004.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 2998-3004
-
-
Yao, Z.M.1
Vance, D.E.2
-
192
-
-
0028789050
-
Choline deficiency: A cause of hepatic steatosis during parenteral nutrition that can be reversed with intravenous choline supplementation
-
Buchman, A. L., M. D. Dubin, A. A. Moukarzel, D. J. Jenden, M. Roch, K. M. Rice, J. Gornbein, and M. E. Ament. 1995. Choline deficiency: a cause of hepatic steatosis during parenteral nutrition that can be reversed with intravenous choline supplementation. Hepatology. 22: 1399-1403.
-
(1995)
Hepatology
, vol.22
, pp. 1399-1403
-
-
Buchman, A.L.1
Dubin, M.D.2
Moukarzel, A.A.3
Jenden, D.J.4
Roch, M.5
Rice, K.M.6
Gornbein, J.7
Ament, M.E.8
-
193
-
-
23444435961
-
Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD)
-
Song, J., K. A. da Costa, L. M. Fischer, M. Kohlmeier, L. Kwock, S. Wang, and S. H. Zeisel. 2005. Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). FASEB J. 19: 1266-1271.
-
(2005)
FASEB J.
, vol.19
, pp. 1266-1271
-
-
Song, J.1
Da Costa, K.A.2
Fischer, L.M.3
Kohlmeier, M.4
Kwock, L.5
Wang, S.6
Zeisel, S.H.7
-
194
-
-
33750102875
-
No association between polymorphism in PEMT (V175M) and hepatic triglyceride content in the Dallas Heart Study
-
author reply 2181-2182
-
Romeo, S., J. C. Cohen, and H. H. Hobbs. 2006. No association between polymorphism in PEMT (V175M) and hepatic triglyceride content in the Dallas Heart Study. FASEB J. 20: 2180 ; author reply 2181-2182.
-
(2006)
FASEB J.
, vol.20
, pp. 2180
-
-
Romeo, S.1
Cohen, J.C.2
Hobbs, H.H.3
-
195
-
-
34047116836
-
The phosphatidylethanolamine N-methyltransferase gene V175M single nucleotide polymorphism confers the susceptibility to NASH in Japanese population
-
DOI 10.1016/j.jhep.2006.12.012, PII S0168827807000359
-
Dong, H., J. Wang, C. Li, A. Hirose, Y. Nozaki, M. Takahashi, M. Ono, N. Akisawa, S. Iwasaki, T. Saibara, et al. 2007. The phosphatidylethanolamine N-methyltransferase gene V175M single nucleotide polymorphism confers the susceptibility to NASH in Japanese population. J. Hepatol. 46: 915-920. (Pubitemid 46529040)
-
(2007)
Journal of Hepatology
, vol.46
, Issue.5
, pp. 915-920
-
-
Dong, H.1
Wang, J.2
Li, C.3
Hirose, A.4
Nozaki, Y.5
Takahashi, M.6
Ono, M.7
Akisawa, N.8
Iwasaki, S.9
Saibara, T.10
Onishi, S.11
-
196
-
-
67649649783
-
Polymorphisms of microsomal triglyceride transfer protein gene and phosphatidylethanolamine N-methyltransferase gene in alcoholic and nonalcoholic fatty liver disease in Koreans
-
Jun, D. W., J. H. Han, E. C. Jang, S. H. Kim, Y. J. Jo, Y. S. Park, and J. D. Chae. 2009. Polymorphisms of microsomal triglyceride transfer protein gene and phosphatidylethanolamine N-methyltransferase gene in alcoholic and nonalcoholic fatty liver disease in Koreans. Eur. J. Gastroenterol. Hepatol. 21: 667-672.
-
(2009)
Eur. J. Gastroenterol. Hepatol.
, vol.21
, pp. 667-672
-
-
Jun, D.W.1
Han, J.H.2
Jang, E.C.3
Kim, S.H.4
Jo, Y.J.5
Park, Y.S.6
Chae, J.D.7
-
198
-
-
77952049390
-
The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease
-
Polyzos, S. A., J. Kountouras, C. Zavos, and E. Tsiaousi. 2010. The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease. Diabetes Obes. Metab. 12: 365-383.
-
(2010)
Diabetes Obes. Metab.
, vol.12
, pp. 365-383
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
Tsiaousi, E.4
-
199
-
-
42249084876
-
Adiponectin gene polymorphisms modulate acute adiponectin response to dietary fat: Possible pathogenetic role in NASH
-
DOI 10.1002/hep.22142
-
Musso, G., R. Gambino, F. De Michieli, M. Durazzo, G. Pagano, and M. Cassader. 2008. Adiponectin gene polymorphisms modulate acute adiponectin response to dietary fat: possible pathogenetic role in NASH. Hepatology. 47: 1167-1177. (Pubitemid 351547903)
-
(2008)
Hepatology
, vol.47
, Issue.4
, pp. 1167-1177
-
-
Musso, G.1
Gambino, R.2
De Michieli, F.3
Durazzo, M.4
Pagano, G.5
Cassader, M.6
-
200
-
-
70349652353
-
Influence of adiponectin gene polymorphisms in Japanese patients with non-alcoholic fatty liver disease
-
Tokushige, K., E. Hashimoto, H. Noto, S. Yatsuji, M. Taniai, N. Torii, and K. Shiratori. 2009. Influence of adiponectin gene polymorphisms in Japanese patients with non-alcoholic fatty liver disease. J. Gastroenterol. 44: 976-982.
-
(2009)
J. Gastroenterol.
, vol.44
, pp. 976-982
-
-
Tokushige, K.1
Hashimoto, E.2
Noto, H.3
Yatsuji, S.4
Taniai, M.5
Torii, N.6
Shiratori, K.7
-
201
-
-
41849104107
-
The influence of the adiponectin gene on adiponectin concentrations and parameters of metabolic syndrome in non-diabetic Korean women
-
Jang, Y., J. S. Chae, S. J. Koh, Y. J. Hyun, J. Y. Kim, Y. J. Jeong, S. Park, C. M. Ahn, and J. H. Lee. 2008. The influence of the adiponectin gene on adiponectin concentrations and parameters of metabolic syndrome in non-diabetic Korean women. Clin. Chim. Acta. 391: 85-90.
-
(2008)
Clin. Chim. Acta
, vol.391
, pp. 85-90
-
-
Jang, Y.1
Chae, J.S.2
Koh, S.J.3
Hyun, Y.J.4
Kim, J.Y.5
Jeong, Y.J.6
Park, S.7
Ahn, C.M.8
Lee, J.H.9
-
202
-
-
27744570794
-
Association of the 276G → T polymorphism of the adiponectin gene with cardiovascular disease risk factors in nondiabetic Koreans
-
Jang, Y., J. H. Lee, J. S. Chae, O. Y. Kim, S. J. Koh, J. Y. Kim, H. Cho, J. E. Lee, and J. M. Ordovas. 2005. Association of the 276G → T polymorphism of the adiponectin gene with cardiovascular disease risk factors in nondiabetic Koreans. Am. J. Clin. Nutr. 82: 760-767.
-
(2005)
Am. J. Clin. Nutr.
, vol.82
, pp. 760-767
-
-
Jang, Y.1
Lee, J.H.2
Chae, J.S.3
Kim, O.Y.4
Koh, S.J.5
Kim, J.Y.6
Cho, H.7
Lee, J.E.8
Ordovas, J.M.9
-
203
-
-
12944281686
-
Effect of adiponectin gene polymorphisms on circulating adiponectin and insulin resistance indexes in women with polycystic ovary syndrome
-
Xita, N., I. Georgiou, A. Chatzikyriakidou, M. Vounatsou, G. P. Papassotiriou, I. Papassotiriou, and A. Tsatsoulis. 2005. Effect of adiponectin gene polymorphisms on circulating adiponectin and insulin resistance indexes in women with polycystic ovary syndrome. Clin. Chem. 51: 416-423.
-
(2005)
Clin. Chem.
, vol.51
, pp. 416-423
-
-
Xita, N.1
Georgiou, I.2
Chatzikyriakidou, A.3
Vounatsou, M.4
Papassotiriou, G.P.5
Papassotiriou, I.6
Tsatsoulis, A.7
-
204
-
-
44949172829
-
Genetic polymorphisms of adiponectin and tumor necrosis factor-alpha and nonalcoholic fatty liver disease in Chinese people
-
Wong, V. W., G. L. Wong, S. W. Tsang, A. Y. Hui, A. W. Chan, P. C. Choi, W. Y. So, A. M. Tse, F. K. Chan, J. J. Sung, et al. 2008. Genetic polymorphisms of adiponectin and tumor necrosis factor-alpha and nonalcoholic fatty liver disease in Chinese people. J. Gastroenterol. Hepatol. 23: 914-921.
-
(2008)
J. Gastroenterol. Hepatol.
, vol.23
, pp. 914-921
-
-
Wong, V.W.1
Wong, G.L.2
Tsang, S.W.3
Hui, A.Y.4
Chan, A.W.5
Choi, P.C.6
So, W.Y.7
Tse, A.M.8
Chan, F.K.9
Sung, J.J.10
-
205
-
-
63049122519
-
Correlation between adiponectin polymorphisms and non-alcoholic fatty liver disease with or without metabolic syndrome in Chinese population
-
Wang, Z. L., B. Xia, U. Shrestha, L. Jiang, C. W. Ma, Q. Chen, H. Chen, and Z. G. Hu. 2008. Correlation between adiponectin polymorphisms and non-alcoholic fatty liver disease with or without metabolic syndrome in Chinese population. J. Endocrinol. Invest. 31: 1086-1091.
-
(2008)
J. Endocrinol. Invest.
, vol.31
, pp. 1086-1091
-
-
Wang, Z.L.1
Xia, B.2
Shrestha, U.3
Jiang, L.4
Ma, C.W.5
Chen, Q.6
Chen, H.7
Hu, Z.G.8
-
206
-
-
64549115439
-
Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts
-
Kotronen, A., H. Yki-Jarvinen, A. Aminoff, R. Bergholm, K. H. Pietilainen, J. Westerbacka, P. J. Talmud, S. E. Humphries, A. Hamsten, B. Isomaa, et al. 2009. Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts. Eur. J. Endocrinol. 160: 593-602.
-
(2009)
Eur. J. Endocrinol.
, vol.160
, pp. 593-602
-
-
Kotronen, A.1
Yki-Jarvinen, H.2
Aminoff, A.3
Bergholm, R.4
Pietilainen, K.H.5
Westerbacka, J.6
Talmud, P.J.7
Humphries, S.E.8
Hamsten, A.9
Isomaa, B.10
-
207
-
-
27744492082
-
Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat
-
Stefan, N., F. Machicao, H. Staiger, J. Machann, F. Schick, O. Tschritter, C. Spieth, C. Weigert, A. Fritsche, M. Stumvoll, et al. 2005. Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat. Diabetologia. 48: 2282-2291.
-
(2005)
Diabetologia
, vol.48
, pp. 2282-2291
-
-
Stefan, N.1
Machicao, F.2
Staiger, H.3
Machann, J.4
Schick, F.5
Tschritter, O.6
Spieth, C.7
Weigert, C.8
Fritsche, A.9
Stumvoll, M.10
-
208
-
-
77149168465
-
Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease
-
Dongiovanni, P., L. Valenti, R. Rametta, A. K. Daly, V. Nobili, E. Mozzi, J. B. Leathart, A. Pietrobattista, A. D. Burt, M. Maggioni, et al. 2010. Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease. Gut. 59: 267-273.
-
(2010)
Gut
, vol.59
, pp. 267-273
-
-
Dongiovanni, P.1
Valenti, L.2
Rametta, R.3
Daly, A.K.4
Nobili, V.5
Mozzi, E.6
Leathart, J.B.7
Pietrobattista, A.8
Burt, A.D.9
Maggioni, M.10
-
209
-
-
0042572474
-
Gly972Arg variant in the insulin receptor substrate- 1 gene and association with type 2 diabetes: A meta-analysis of 27 studies
-
Jellema, A., M. P. Zeegers, E. J. Feskens, P. C. Dagnelie, and R. P. Mensink. 2003. Gly972Arg variant in the insulin receptor substrate- 1 gene and association with type 2 diabetes: a meta-analysis of 27 studies. Diabetologia. 46: 990-995.
-
(2003)
Diabetologia
, vol.46
, pp. 990-995
-
-
Jellema, A.1
Zeegers, M.P.2
Feskens, E.J.3
Dagnelie, P.C.4
Mensink, R.P.5
-
210
-
-
33845478157
-
Editorial: The pleiotropic effect of the ENPP1 (PC-1) gene on insulin resistance, obesity, and type 2 diabetes
-
Prudente, S., and V. Trischitta. 2006. Editorial: The pleiotropic effect of the ENPP1 (PC-1) gene on insulin resistance, obesity, and type 2 diabetes. J. Clin. Endocrinol. Metab. 91: 4767-4768.
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, pp. 4767-4768
-
-
Prudente, S.1
Trischitta, V.2
-
211
-
-
33644660537
-
PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease
-
Finck, B. N., and D. P. Kelly. 2006. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J. Clin. Invest. 116: 615-622.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 615-622
-
-
Finck, B.N.1
Kelly, D.P.2
-
212
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin, J., C. Handschin, and B. M. Spiegelman. 2005. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 1: 361-370.
-
(2005)
Cell Metab.
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
213
-
-
49649084735
-
Nuclear receptors, mitochondria and lipid metabolism
-
Alaynick, W. A. 2008. Nuclear receptors, mitochondria and lipid metabolism. Mitochondrion. 8: 329-337.
-
(2008)
Mitochondrion
, vol.8
, pp. 329-337
-
-
Alaynick, W.A.1
-
214
-
-
0035855905
-
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
-
DOI 10.1038/35093131
-
Herzig, S., F. Long, U. S. Jhala, S. Hedrick, R. Quinn, A. Bauer, D. Rudolph, G. Schutz, C. Yoon, P. Puigserver, et al. 2001. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature. 413: 179-183. (Pubitemid 32867880)
-
(2001)
Nature
, vol.413
, Issue.6852
, pp. 179-183
-
-
Herzig, S.1
Long, F.2
Jhala, U.S.3
Hedrick, S.4
Quinn, R.5
Bauer, A.6
Rudolph, D.7
Schutz, G.8
Yoon, C.9
Puigserver, P.10
Spiegelman, B.11
Montminy, M.12
-
215
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
DOI 10.1038/nature01667
-
Puigserver, P., J. Rhee, J. Donovan, C. J. Walkey, J. C. Yoon, F. Oriente, Y. Kitamura, J. Altomonte, H. Dong, D. Accili, et al. 2003. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature. 423: 550-555. (Pubitemid 36648580)
-
(2003)
Nature
, vol.423
, Issue.6939
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
Kitamura, Y.7
Altomonte, J.8
Dong, H.9
Accili, D.10
Spiegelman, B.M.11
-
216
-
-
67650242167
-
Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression
-
Estall, J. L., M. Kahn, M. P. Cooper, F. M. Fisher, M. K. Wu, D. Laznik, L. Qu, D. E. Cohen, G. I. Shulman, and B. M. Spiegelman. 2009. Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression. Diabetes. 58: 1499-1508.
-
(2009)
Diabetes
, vol.58
, pp. 1499-1508
-
-
Estall, J.L.1
Kahn, M.2
Cooper, M.P.3
Fisher, F.M.4
Wu, M.K.5
Laznik, D.6
Qu, L.7
Cohen, D.E.8
Shulman, G.I.9
Spiegelman, B.M.10
-
217
-
-
21144446106
-
PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis
-
Leone, T. C., J. J. Lehman, B. N. Finck, P. J. Schaeffer, A. R. Wende, S. Boudina, M. Courtois, D. F. Wozniak, N. Sambandam, C. Bernal-Mizrachi, et al. 2005. PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol. 3: e101.
-
(2005)
PLoS Biol.
, vol.3
-
-
Leone, T.C.1
Lehman, J.J.2
Finck, B.N.3
Schaeffer, P.J.4
Wende, A.R.5
Boudina, S.6
Courtois, M.7
Wozniak, D.F.8
Sambandam, N.9
Bernal-Mizrachi, C.10
-
218
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coaotivator PGC-1
-
DOI 10.1038/35093050
-
Yoon, J. C., P. Puigserver, G. Chen, J. Donovan, Z. Wu, J. Rhee, G. Adelmant, J. Stafford, C. R. Kahn, D. K. Granner, et al. 2001. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature. 413: 131-138. (Pubitemid 32867868)
-
(2001)
Nature
, vol.413
, Issue.6852
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
Rhee, J.6
Adelmant, G.7
Stafford, J.8
Kahn, C.R.9
Granner, D.K.10
Newgard, C.B.11
Spiegelman, B.M.12
-
219
-
-
4644351862
-
PPARalpha in the pathogenesis of fatty liver disease
-
Rao, M. S., and J. K. Reddy. 2004. PPARalpha in the pathogenesis of fatty liver disease. Hepatology. 40: 783-786.
-
(2004)
Hepatology
, vol.40
, pp. 783-786
-
-
Rao, M.S.1
Reddy, J.K.2
-
220
-
-
33751545838
-
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
-
Belfort, R., S. A. Harrison, K. Brown, C. Darland, J. Finch, J. Hardies, B. Balas, A. Gastaldelli, F. Tio, J. Pulcini, et al. 2006. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N. Engl. J. Med. 355: 2297-2307.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 2297-2307
-
-
Belfort, R.1
Harrison, S.A.2
Brown, K.3
Darland, C.4
Finch, J.5
Hardies, J.6
Balas, B.7
Gastaldelli, A.8
Tio, F.9
Pulcini, J.10
-
221
-
-
47749134925
-
Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)
-
Yoneda, M., K. Hotta, Y. Nozaki, H. Endo, T. Uchiyama, H. Mawatari, H. Iida, S. Kato, K. Hosono, K. Fujita, et al. 2008. Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD). BMC Gastroenterol. 8: 27.
-
(2008)
BMC Gastroenterol.
, vol.8
, pp. 27
-
-
Yoneda, M.1
Hotta, K.2
Nozaki, Y.3
Endo, H.4
Uchiyama, T.5
Mawatari, H.6
Iida, H.7
Kato, S.8
Hosono, K.9
Fujita, K.10
-
222
-
-
39549113664
-
Effect of peroxisome proliferator-activated receptors-gamma and co-activator-1alpha genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people
-
DOI 10.1111/j.1478-3231.2007.01623.x
-
Hui, Y., L. Yu-Yuan, N. Yu-Qiang, S. Wei-Hong, D. Yan-Lei, L. Xiao-Bo, and Z. Yong-Jian. 2008. Effect of peroxisome proliferator- activated receptors-gamma and co-activator-1alpha genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people. Liver Int. 28: 385-392. (Pubitemid 351279587)
-
(2008)
Liver International
, vol.28
, Issue.3
, pp. 385-392
-
-
Hui, Y.1
Yu-yuan, L.2
Yu-qiang, N.3
Wei-hong, S.4
Yan-lei, D.5
Xiao-bo, L.6
Yong-jian, Z.7
-
223
-
-
0036228574
-
Peroxisome proliferator-activated receptor-gamma coactivator-1 gene locus: Associations with obesity indices in middle-aged women
-
Esterbauer, H., H. Oberkofler, V. Linnemayr, B. Iglseder, M. Hedegger, P. Wolfsgruber, B. Paulweber, G. Fastner, F. Krempler, and W. Patsch. 2002. Peroxisome proliferator-activated receptorgamma coactivator-1 gene locus: associations with obesity indices in middle-aged women. Diabetes. 51: 1281-1286. (Pubitemid 34438380)
-
(2002)
Diabetes
, vol.51
, Issue.4
, pp. 1281-1286
-
-
Esterbauer, H.1
Oberkofler, H.2
Linnemayr, V.3
Iglseder, B.4
Hedegger, M.5
Wolfsgruber, P.6
Paulweber, B.7
Fastner, G.8
Krempler, F.9
Patsch, W.10
-
224
-
-
0035985096
-
A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes
-
DOI 10.1007/s00125-002-0803-z
-
Hara, K., K. Tobe, T. Okada, H. Kadowaki, Y. Akanuma, C. Ito, S. Kimura, and T. Kadowaki. 2002. A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to type II diabetes. Diabetologia. 45: 740-743. (Pubitemid 34810700)
-
(2002)
Diabetologia
, vol.45
, Issue.5
, pp. 740-743
-
-
Hara, K.1
Tobe, K.2
Okada, T.3
Kadowaki, H.4
Akanuma, Y.5
Ito, C.6
Kimura, S.7
Kadowaki, T.8
-
225
-
-
0037318370
-
Peroxisome proliferator-activated receptor-gamma coactivator-1 gene locus: Associations with hypertension in middle-aged men
-
DOI 10.1161/01.HYP.0000050962.48249.B7
-
Oberkofler, H., B. Holzl, H. Esterbauer, M. Xie, B. Iglseder, F. Krempler, B. Paulweber, and W. Patsch. 2003. Peroxisome proliferator- activated receptor-gamma coactivator-1 gene locus: associations with hypertension in middle-aged men. Hypertension. 41: 368-372. (Pubitemid 36204916)
-
(2003)
Hypertension
, vol.41
, Issue.2
, pp. 368-372
-
-
Oberkofler, H.1
Holzl, B.2
Esterbauer, H.3
Xie, M.4
Iglseder, B.5
Krempler, F.6
Paulweber, B.7
Patsch, W.8
-
226
-
-
2342625303
-
Complex Haplotypes of the PGC-1alpha Gene Are Associated with Carbohydrate Metabolism and Type 2 Diabetes
-
DOI 10.2337/diabetes.53.5.1385
-
Oberkofler, H., V. Linnemayr, R. Weitgasser, K. Klein, M. Xie, B. Iglseder, F. Krempler, B. Paulweber, and W. Patsch. 2004. Complex haplotypes of the PGC-1alpha gene are associated with carbohydrate metabolism and type 2 diabetes. Diabetes. 53: 1385-1393. (Pubitemid 38569027)
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1385-1393
-
-
Oberkofler, H.1
Linnemayr, V.2
Weitgasser, R.3
Klein, K.4
Xie, M.5
Iglseder, B.6
Krempler, F.7
Paulweber, B.8
Patsch, W.9
-
227
-
-
23944464632
-
Haplotypes of PPARGC1A are associated with glucose tolerance, body mass index and insulin sensitivity in offspring of patients with type 2 diabetes
-
DOI 10.1007/s00125-005-1800-9
-
Pihlajamaki, J., M. Kinnunen, E. Ruotsalainen, U. Salmenniemi, I. Vauhkonen, T. Kuulasmaa, S. Kainulainen, and M. Laakso. 2005. Haplotypes of PPARGC1A are associated with glucose tolerance, body mass index and insulin sensitivity in offspring of patients with type 2 diabetes. Diabetologia. 48: 1331-1334. (Pubitemid 41186098)
-
(2005)
Diabetologia
, vol.48
, Issue.7
, pp. 1331-1334
-
-
Pihlajamaki, J.1
Kinnunen, M.2
Ruotsalainen, E.3
Salmenniemi, U.4
Vauhkonen, I.5
Kuulasmaa, T.6
Kainulainen, S.7
Laakso, M.8
-
228
-
-
33244470881
-
Increased risk of obesity associated with the variant allele of the PPARGC1A Gly482Ser polymorphism in physically inactive elderly men
-
DOI 10.1007/s00125-005-0129-8
-
Ridderstrale, M., L. E. Johansson, L. Rastam, and U. Lindblad. 2006. Increased risk of obesity associated with the variant allele of the PPARGC1A Gly482Ser polymorphism in physically inactive elderly men. Diabetologia. 49: 496-500. (Pubitemid 43277872)
-
(2006)
Diabetologia
, vol.49
, Issue.3
, pp. 496-500
-
-
Ridderstrale, M.1
Johansson, L.E.2
Rastam, L.3
Lindblad, U.4
-
229
-
-
33244465167
-
Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes
-
Barroso, I., J. Luan, M. S. Sandhu, P. W. Franks, V. Crowley, A. J. Schafer, S. O'Rahilly, and N. J. Wareham. 2006. Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes. Diabetologia. 49: 501-505.
-
(2006)
Diabetologia
, vol.49
, pp. 501-505
-
-
Barroso, I.1
Luan, J.2
Sandhu, M.S.3
Franks, P.W.4
Crowley, V.5
Schafer, A.J.6
O'Rahilly, S.7
Wareham, N.J.8
-
230
-
-
85047691371
-
Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins
-
Ling, C., P. Poulsen, E. Carlsson, M. Ridderstrale, P. Almgren, J. Wojtaszewski, H. Beck-Nielsen, L. Groop, and A. Vaag. 2004. Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins. J. Clin. Invest. 114: 1518-1526.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1518-1526
-
-
Ling, C.1
Poulsen, P.2
Carlsson, E.3
Ridderstrale, M.4
Almgren, P.5
Wojtaszewski, J.6
Beck-Nielsen, H.7
Groop, L.8
Vaag, A.9
-
231
-
-
33846828211
-
PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge
-
Franks, P. W., U. Ekelund, S. Brage, J. Luan, A. J. Schafer, S. O'Rahilly, I. Barroso, and N. J. Wareham. 2007. PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge. Diabetologia. 50: 569-573.
-
(2007)
Diabetologia
, vol.50
, pp. 569-573
-
-
Franks, P.W.1
Ekelund, U.2
Brage, S.3
Luan, J.4
Schafer, A.J.5
O'Rahilly, S.6
Barroso, I.7
Wareham, N.J.8
-
232
-
-
49849093922
-
A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio
-
Chen, S., Y. Li, S. Li, and C. Yu. 2008. A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio. J. Gastroenterol. Hepatol. 23: 1415-1418.
-
(2008)
J. Gastroenterol. Hepatol.
, vol.23
, pp. 1415-1418
-
-
Chen, S.1
Li, Y.2
Li, S.3
Yu, C.4
-
233
-
-
34447340935
-
TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: A global meta-analysis
-
Cauchi, S., Y. El Achhab, H. Choquet, C. Dina, F. Krempler, R. Weitgasser, C. Nejjari, W. Patsch, M. Chikri, D. Meyre, et al. 2007. TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J. Mol. Med. 85: 777-782.
-
(2007)
J. Mol. Med.
, vol.85
, pp. 777-782
-
-
Cauchi, S.1
El Achhab, Y.2
Choquet, H.3
Dina, C.4
Krempler, F.5
Weitgasser, R.6
Nejjari, C.7
Patsch, W.8
Chikri, M.9
Meyre, D.10
-
234
-
-
33750889376
-
Transcription factor TCF7L2 genetic study in the French population: Expression in human beta-cells and adipose tissue and strong association with type 2 diabetes
-
DOI 10.2337/db06-0474
-
Cauchi, S., D. Meyre, C. Dina, H. Choquet, C. Samson, S. Gallina, B. Balkau, G. Charpentier, F. Pattou, V. Stetsyuk, et al. 2006. Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes. Diabetes. 55: 2903-2908. (Pubitemid 44923694)
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2903-2908
-
-
Cauchi, S.1
Meyre, D.2
Dina, C.3
Choquet, H.4
Samson, C.5
Gallina, S.6
Balkau, B.7
Charpentier, G.8
Pattou, F.9
Stetsyuk, V.10
Scharfmann, R.11
Staels, B.12
Fruhbeck, G.13
Froguel, P.14
-
235
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant, S. F., G. Thorleifsson, I. Reynisdottir, R. Benediktsson, A. Manolescu, J. Sainz, A. Helgason, H. Stefansson, V. Emilsson, A. Helgadottir, et al. 2006. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat. Genet. 38: 320-323.
-
(2006)
Nat. Genet.
, vol.38
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
Helgason, A.7
Stefansson, H.8
Emilsson, V.9
Helgadottir, A.10
-
236
-
-
36649027501
-
TCF7L2 is associated with high serum triacylglycerol and differentially expressed in adipose tissue in families with familial combined hyperlipidaemia
-
DOI 10.1007/s00125-007-0850-6
-
Huertas-Vazquez, A., C. Plaisier, D. Weissglas-Volkov, J. Sinsheimer, S. Canizales-Quinteros, I. Cruz-Bautista, E. Nikkola, M. Herrera-Hernandez, A. Davila-Cervantes, T. Tusie-Luna, et al. 2008. TCF7L2 is associated with high serum triacylglycerol and differentially expressed in adipose tissue in families with familial combined hyperlipidaemia. Diabetologia. 51: 62-69. (Pubitemid 50000014)
-
(2008)
Diabetologia
, vol.51
, Issue.1
, pp. 62-69
-
-
Huertas-Vazquez, A.1
Plaisier, C.2
Weissglas-Volkov, D.3
Sinsheimer, J.4
Canizales-Quinteros, S.5
Cruz-Bautista, I.6
Nikkola, E.7
Herrera-Hernandez, M.8
Davila-Cervantes, A.9
Tusie-Luna, T.10
Taskinen, M.-R.11
Aguilar-Salinas, C.12
Pajukanta, P.13
-
237
-
-
61949437406
-
Transcription factor 7-like 2 polymorphism modulates glucose and lipid homeostasis, adipokine profile, and hepatocyte apoptosis in NASH
-
Musso, G., R. Gambino, G. Pacini, G. Pagano, M. Durazzo, and M. Cassader. 2009. Transcription factor 7-like 2 polymorphism modulates glucose and lipid homeostasis, adipokine profile, and hepatocyte apoptosis in NASH. Hepatology. 49: 426-435.
-
(2009)
Hepatology
, vol.49
, pp. 426-435
-
-
Musso, G.1
Gambino, R.2
Pacini, G.3
Pagano, G.4
Durazzo, M.5
Cassader, M.6
-
238
-
-
2642583241
-
The ins and outs of mitochondrial dysfunction in NASH
-
Fromenty, B., M. A. Robin, A. Igoudjil, A. Mansouri, and D. Pessayre. 2004. The ins and outs of mitochondrial dysfunction in NASH. Diabetes Metab. 30: 121-138. (Pubitemid 38715168)
-
(2004)
Diabetes and Metabolism
, vol.30
, Issue.2
, pp. 121-138
-
-
Fromenty, B.1
Robin, M.A.2
Igoudjil, A.3
Mansouri, A.4
Pessayre, D.5
-
239
-
-
0035991444
-
In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
-
Seki, S., T. Kitada, T. Yamada, H. Sakaguchi, K. Nakatani, and K. Wakasa. 2002. In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases. J. Hepatol. 37: 56-62.
-
(2002)
J. Hepatol.
, vol.37
, pp. 56-62
-
-
Seki, S.1
Kitada, T.2
Yamada, T.3
Sakaguchi, H.4
Nakatani, K.5
Wakasa, K.6
-
240
-
-
77956921023
-
The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways
-
Gao, D., S. Nong, X. Huang, Y. Lu, H. Zhao, Y. Lin, Y. Man, S. Wang, J. Yang, and J. Li. 2010. The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways. J. Biol. Chem. 285: 29965-29973.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 29965-29973
-
-
Gao, D.1
Nong, S.2
Huang, X.3
Lu, Y.4
Zhao, H.5
Lin, Y.6
Man, Y.7
Wang, S.8
Yang, J.9
Li, J.10
-
241
-
-
33847026801
-
Ceramide-and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells
-
JeBailey, L., O. Wanono, W. Niu, J. Roessler, A. Rudich, and A. Klip. 2007. Ceramide-and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells. Diabetes. 56: 394-403.
-
(2007)
Diabetes
, vol.56
, pp. 394-403
-
-
JeBailey, L.1
Wanono, O.2
Niu, W.3
Roessler, J.4
Rudich, A.5
Klip, A.6
-
242
-
-
14844288046
-
Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients
-
DOI 10.1016/j.jhep.2004.11.040
-
Malaguarnera, L., R. Madeddu, E. Palio, N. Arena, and M. Malaguarnera. 2005. Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients. J. Hepatol. 42: 585-591. (Pubitemid 40342940)
-
(2005)
Journal of Hepatology
, vol.42
, Issue.4
, pp. 585-591
-
-
Malaguarnera, L.1
Madeddu, R.2
Palio, E.3
Arena, N.4
Malaguarnera, M.5
-
243
-
-
34248641168
-
Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure
-
Chen, Y., Y. Yang, M. L. Miller, D. Shen, H. G. Shertzer, K. F. Stringer, B. Wang, S. N. Schneider, D. W. Nebert, and T. P. Dalton. 2007. Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure. Hepatology. 45: 1118-1128.
-
(2007)
Hepatology
, vol.45
, pp. 1118-1128
-
-
Chen, Y.1
Yang, Y.2
Miller, M.L.3
Shen, D.4
Shertzer, H.G.5
Stringer, K.F.6
Wang, B.7
Schneider, S.N.8
Nebert, D.W.9
Dalton, T.P.10
-
244
-
-
76149095904
-
Association of polymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease
-
Oliveira, C. P., J. T. Stefano, A. M. Cavaleiro, M. A. Fortes, S. M. Vieira, V. M. Lima, T. E. Santos, V. N. Santos, A. L. de Azevedo Salgado, E. R. Parise, et al. 2010. Association of polymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease. J. Gastroenterol. Hepatol. 25: 357-361.
-
(2010)
J. Gastroenterol. Hepatol.
, vol.25
, pp. 357-361
-
-
Oliveira, C.P.1
Stefano, J.T.2
Cavaleiro, A.M.3
Fortes, M.A.4
Vieira, S.M.5
Lima, V.M.6
Santos, T.E.7
Santos, V.N.8
De Azevedo Salgado, A.L.9
Parise, E.R.10
-
245
-
-
0037454012
-
Association of polymorphism in glutamate-cysteine ligase catalytic subunit gene with coronary vasomotor dysfunction and myocardial infarction
-
Koide, S., K. Kugiyama, S. Sugiyama, S. Nakamura, H. Fukushima, O. Honda, M. Yoshimura, and H. Ogawa. 2003. Association of polymorphism in glutamate-cysteine ligase catalytic subunit gene with coronary vasomotor dysfunction and myocardial infarction. J. Am. Coll. Cardiol. 41: 539-545.
-
(2003)
J. Am. Coll. Cardiol.
, vol.41
, pp. 539-545
-
-
Koide, S.1
Kugiyama, K.2
Sugiyama, S.3
Nakamura, S.4
Fukushima, H.5
Honda, O.6
Yoshimura, M.7
Ogawa, H.8
-
246
-
-
73849101167
-
Influence of inducible nitric oxide synthase polymorphisms in Japanese patients with non-alcoholic fatty liver disease
-
Yoneda, M., K. Hotta, Y. Nozaki, H. Endo, W. Tomeno, S. Watanabe, K. Hosono, H. Mawatari, H. Iida, K. Fujita, et al. 2009. Influence of inducible nitric oxide synthase polymorphisms in Japanese patients with non-alcoholic fatty liver disease. Hepatol. Res. 39: 963-971.
-
(2009)
Hepatol. Res.
, vol.39
, pp. 963-971
-
-
Yoneda, M.1
Hotta, K.2
Nozaki, Y.3
Endo, H.4
Tomeno, W.5
Watanabe, S.6
Hosono, K.7
Mawatari, H.8
Iida, H.9
Fujita, K.10
-
247
-
-
33644790277
-
Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: Implications in atherogenesis
-
Dickhout, J. G., G. S. Hossain, L. M. Pozza, J. Zhou, S. Lhotak, and R. C. Austin. 2005. Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arterioscler. Thromb. Vasc. Biol. 25: 2623-2629.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 2623-2629
-
-
Dickhout, J.G.1
Hossain, G.S.2
Pozza, L.M.3
Zhou, J.4
Lhotak, S.5
Austin, R.C.6
-
248
-
-
0036894470
-
Valinealanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis
-
Stewart, S. F., J. B. Leathart, Y. Chen, A. K. Daly, R. Rolla, D. Vay, E. Mottaran, M. Vidali, E. Albano, and C. P. Day. 2002. Valinealanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis. Hepatology. 36: 1355-1360.
-
(2002)
Hepatology
, vol.36
, pp. 1355-1360
-
-
Stewart, S.F.1
Leathart, J.B.2
Chen, Y.3
Daly, A.K.4
Rolla, R.5
Vay, D.6
Mottaran, E.7
Vidali, M.8
Albano, E.9
Day, C.P.10
-
249
-
-
34548719343
-
Role of STAT3 in liver regeneration: Survival, DNA synthesis, inflammatory reaction and liver mass recovery
-
Moh, A., Y. Iwamoto, G. X. Chai, S. S. Zhang, A. Kano, D. D. Yang, W. Zhang, J. Wang, J. J. Jacoby, B. Gao, et al. 2007. Role of STAT3 in liver regeneration: survival, DNA synthesis, inflammatory reaction and liver mass recovery. Lab. Invest. 87: 1018-1028.
-
(2007)
Lab. Invest.
, vol.87
, pp. 1018-1028
-
-
Moh, A.1
Iwamoto, Y.2
Chai, G.X.3
Zhang, S.S.4
Kano, A.5
Yang, D.D.6
Zhang, W.7
Wang, J.8
Jacoby, J.J.9
Gao, B.10
-
250
-
-
11144357516
-
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo
-
Inoue, H., W. Ogawa, M. Ozaki, S. Haga, M. Matsumoto, K. Furukawa, N. Hashimoto, Y. Kido, T. Mori, H. Sakaue, et al. 2004. Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo. Nat. Med. 10: 168-174.
-
(2004)
Nat. Med.
, vol.10
, pp. 168-174
-
-
Inoue, H.1
Ogawa, W.2
Ozaki, M.3
Haga, S.4
Matsumoto, M.5
Furukawa, K.6
Hashimoto, N.7
Kido, Y.8
Mori, T.9
Sakaue, H.10
-
251
-
-
4644237206
-
Interleukin 6 alleviates hepatic steatosis and ischemia/reperfusion injury in mice with fatty liver disease
-
DOI 10.1002/hep.20400
-
Hong, F., S. Radaeva, H. N. Pan, Z. Tian, R. Veech, and B. Gao. 2004. Interleukin 6 alleviates hepatic steatosis and ischemia/ reperfusion injury in mice with fatty liver disease. Hepatology. 40: 933-941. (Pubitemid 39288127)
-
(2004)
Hepatology
, vol.40
, Issue.4
, pp. 933-941
-
-
Hong, F.1
Radaeva, S.2
Pan, H.-N.3
Tian, Z.4
Veech, R.5
Gao, B.6
-
252
-
-
52949122489
-
Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease
-
Sookoian, S., G. Castano, T. F. Gianotti, C. Gemma, M. S. Rosselli, and C. J. Pirola. 2008. Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease. Cytokine. 44: 201-206.
-
(2008)
Cytokine
, vol.44
, pp. 201-206
-
-
Sookoian, S.1
Castano, G.2
Gianotti, T.F.3
Gemma, C.4
Rosselli, M.S.5
Pirola, C.J.6
-
253
-
-
0035183475
-
Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients
-
DOI 10.1053/jhep.2001.29628
-
Crespo, J., A. Cayon, P. Fernandez-Gil, M. Hernandez-Guerra, M. Mayorga, A. Dominguez-Diez, J. C. Fernandez-Escalante, and F. Pons-Romero. 2001. Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients. Hepatology. 34: 1158-1163. (Pubitemid 33096588)
-
(2001)
Hepatology
, vol.34
, Issue.6
, pp. 1158-1163
-
-
Crespo, J.1
Cayoen, A.2
Fernendez-Gil, P.3
Hernndez-Guerra, M.4
Mayorga, M.5
Domnguez-Dez, A.6
Fernndez-Escalante, J.C.7
Pons-Romero, F.8
-
254
-
-
34247554214
-
Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis
-
DOI 10.1016/j.jhep.2007.01.028, PII S0168827807000761
-
Tokushige, K., M. Takakura, N. Tsuchiya-Matsushita, M. Taniai, E. Hashimoto, and K. Shiratori. 2007. Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis. J. Hepatol. 46: 1104-1110. (Pubitemid 46669735)
-
(2007)
Journal of Hepatology
, vol.46
, Issue.6
, pp. 1104-1110
-
-
Tokushige, K.1
Takakura, M.2
Tsuchiya-Matsushita, N.3
Taniai, M.4
Hashimoto, E.5
Shiratori, K.6
-
255
-
-
17844385292
-
Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C
-
DOI 10.1002/hep.20664
-
Adinolfi, L. E., D. Ingrosso, G. Cesaro, A. Cimmino, M. D'Anto, R. Capasso, V. Zappia, and G. Ruggiero. 2005. Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients. Hepatology. 41: 995-1003. (Pubitemid 40593907)
-
(2005)
Hepatology
, vol.41
, Issue.5
, pp. 995-1003
-
-
Adinolfi, L.E.1
Ingrosso, D.2
Cesaro, G.3
Cimmino, A.4
D'Anto, M.5
Capasso, R.6
Zappia, V.7
Ruggiero, G.8
-
256
-
-
0035014266
-
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways
-
Werstuck, G. H., S. R. Lentz, S. Dayal, G. S. Hossain, S. K. Sood, Y. Y. Shi, J. Zhou, N. Maeda, S. K. Krisans, M. R. Malinow, et al. 2001. Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J. Clin. Invest. 107: 1263-1273.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1263-1273
-
-
Werstuck, G.H.1
Lentz, S.R.2
Dayal, S.3
Hossain, G.S.4
Sood, S.K.5
Shi, Y.Y.6
Zhou, J.7
Maeda, N.8
Krisans, S.K.9
Malinow, M.R.10
-
257
-
-
0031915149
-
Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis
-
George, D. K., S. Goldwurm, G. A. MacDonald, L. L. Cowley, N. I. Walker, P. J. Ward, E. C. Jazwinska, and L. W. Powell. 1998. Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis. Gastroenterology. 114: 311-318.
-
(1998)
Gastroenterology
, vol.114
, pp. 311-318
-
-
George, D.K.1
Goldwurm, S.2
MacDonald, G.A.3
Cowley, L.L.4
Walker, N.I.5
Ward, P.J.6
Jazwinska, E.C.7
Powell, L.W.8
-
258
-
-
0033198317
-
Non-alcoholic steatohepatitis and iron: Increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis
-
Bonkovsky, H. L., Q. Jawaid, K. Tortorelli, P. LeClair, J. Cobb, R. W. Lambrecht, and B. F. Banner. 1999. Non-alcoholic steatohepatitis and iron: increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis. J. Hepatol. 31: 421-429.
-
(1999)
J. Hepatol.
, vol.31
, pp. 421-429
-
-
Bonkovsky, H.L.1
Jawaid, Q.2
Tortorelli, K.3
LeClair, P.4
Cobb, J.5
Lambrecht, R.W.6
Banner, B.F.7
-
259
-
-
0036291809
-
HFE mutations, hepatic iron, and fibrosis: Ethnic-specific association of NASH with C282Y but not with fibrotic severity
-
DOI 10.1053/jhep.2002.33892
-
Chitturi, S., M. Weltman, G. C. Farrell, D. McDonald, J. Kench, C. Liddle, D. Samarasinghe, R. Lin, S. Abeygunasekera, and J. George. 2002. HFE mutations, hepatic iron, and fibrosis: ethnicspecifi c association of NASH with C282Y but not with fibrotic severity. Hepatology. 36: 142-149. (Pubitemid 34700771)
-
(2002)
Hepatology
, vol.36
, Issue.1
, pp. 142-149
-
-
Chitturi, S.1
Weltman, M.2
Farrell, G.C.3
McDonald, D.4
Liddle, C.5
Samarasinghe, D.6
Lin, R.7
Abeygunasekera, S.8
George, J.9
-
260
-
-
0141656292
-
Increased susceptibility to nonalcoholic fatty liver disease in heterozygotes for the mutation responsible for hereditary hemochromatosis
-
Valenti, L., P. Dongiovanni, A. L. Fracanzani, G. Santorelli, E. Fatta, C. Bertelli, E. Taioli, G. Fiorelli, and S. Fargion. 2003. Increased susceptibility to nonalcoholic fatty liver disease in heterozygotes for the mutation responsible for hereditary hemochromatosis. Dig. Liver Dis. 35: 172-178.
-
(2003)
Dig. Liver Dis.
, vol.35
, pp. 172-178
-
-
Valenti, L.1
Dongiovanni, P.2
Fracanzani, A.L.3
Santorelli, G.4
Fatta, E.5
Bertelli, C.6
Taioli, E.7
Fiorelli, G.8
Fargion, S.9
-
261
-
-
2542589434
-
Relative contribution of iron burden, HFE mutations, and insulin resistance to fibrosis in nonalcoholic fatty liver
-
author reply 1749
-
Loria, P., A. Lonardo, and N. Carulli. 2004. Relative contribution of iron burden, HFE mutations, and insulin resistance to fibrosis in nonalcoholic fatty liver. Hepatology. 39: 1748; author reply 1749.
-
(2004)
Hepatology
, vol.39
, pp. 1748
-
-
Loria, P.1
Lonardo, A.2
Carulli, N.3
-
262
-
-
41549138894
-
The HFE gene heterozygosis H63D: A cofactor for liver damage in patients with steatohepatitis? Epidemiological and clinical considerations
-
Neri, S., D. Pulvirenti, S. Signorelli, L. Ignaccolo, A. Tsami, B. Mauceri, M. Misseri, D. Interlandi, N. Cutuli, and P. Castellino. 2008. The HFE gene heterozygosis H63D: a cofactor for liver damage in patients with steatohepatitis? Epidemiological and clinical considerations. Intern. Med. J. 38: 254-258.
-
(2008)
Intern. Med. J.
, vol.38
, pp. 254-258
-
-
Neri, S.1
Pulvirenti, D.2
Signorelli, S.3
Ignaccolo, L.4
Tsami, A.5
Mauceri, B.6
Misseri, M.7
Interlandi, D.8
Cutuli, N.9
Castellino, P.10
-
263
-
-
77249139227
-
HFE genotype, parenchymal iron accumulation, and liver fibrosis in patients with nonalcoholic fatty liver disease
-
Valenti, L., A. L. Fracanzani, E. Bugianesi, P. Dongiovanni, E. Galmozzi, E. Vanni, E. Canavesi, E. Lattuada, G. Roviaro, G. Marchesini, et al. 2010. HFE genotype, parenchymal iron accumulation, and liver fibrosis in patients with nonalcoholic fatty liver disease. Gastroenterology. 138: 905-912.
-
(2010)
Gastroenterology
, vol.138
, pp. 905-912
-
-
Valenti, L.1
Fracanzani, A.L.2
Bugianesi, E.3
Dongiovanni, P.4
Galmozzi, E.5
Vanni, E.6
Canavesi, E.7
Lattuada, E.8
Roviaro, G.9
Marchesini, G.10
-
264
-
-
34548797040
-
HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis
-
Nelson, J. E., R. Bhattacharya, K. D. Lindor, N. Chalasani, S. Raaka, E. J. Heathcote, E. Miskovsky, E. Shaffer, S. J. Rulyak, and K. V. Kowdley. 2007. HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis. Hepatology. 46: 723-729.
-
(2007)
Hepatology
, vol.46
, pp. 723-729
-
-
Nelson, J.E.1
Bhattacharya, R.2
Lindor, K.D.3
Chalasani, N.4
Raaka, S.5
Heathcote, E.J.6
Miskovsky, E.7
Shaffer, E.8
Rulyak, S.J.9
Kowdley, K.V.10
-
265
-
-
12344257645
-
Nonalcoholic steatohepatitis in Asian Indians is neither associated with iron overload nor with HFE gene mutations
-
Duseja, A., R. Das, M. Nanda, A. Das, G. Garewal, and Y. Chawla. 2005. Nonalcoholic steatohepatitis in Asian Indians is neither associated with iron overload nor with HFE gene mutations. World J. Gastroenterol. 11: 393-395.
-
(2005)
World J. Gastroenterol.
, vol.11
, pp. 393-395
-
-
Duseja, A.1
Das, R.2
Nanda, M.3
Das, A.4
Garewal, G.5
Chawla, Y.6
-
266
-
-
22644438762
-
Prevalence of HFE mutations and relation to serum iron status in patients with chronic hepatitis C and patients with nonalcoholic fatty liver disease in Taiwan
-
Lin, T. J., C. L. Lin, C. S. Wang, S. O. Liu, and L. Y. Liao. 2005. Prevalence of HFE mutations and relation to serum iron status in patients with chronic hepatitis C and patients with nonalcoholic fatty liver disease in Taiwan. World J. Gastroenterol. 11: 3905-3908.
-
(2005)
World J. Gastroenterol.
, vol.11
, pp. 3905-3908
-
-
Lin, T.J.1
Lin, C.L.2
Wang, C.S.3
Liu, S.O.4
Liao, L.Y.5
-
267
-
-
67651171476
-
Hyperferritinemia is a risk factor for steatosis in chronic liver disease
-
Licata, A., M. E. Nebbia, G. Cabibbo, G. L. Iacono, F. Barbaria, V. Brucato, N. Alessi, S. Porrovecchio, V. Di Marco, A. Craxi, et al. 2009. Hyperferritinemia is a risk factor for steatosis in chronic liver disease. World J. Gastroenterol. 15: 2132-2138.
-
(2009)
World J. Gastroenterol.
, vol.15
, pp. 2132-2138
-
-
Licata, A.1
Nebbia, M.E.2
Cabibbo, G.3
Iacono, G.L.4
Barbaria, F.5
Brucato, V.6
Alessi, N.7
Porrovecchio, S.8
Di Marco, V.9
Craxi, A.10
-
268
-
-
1442281989
-
Relative Contribution of Iron Burden, HFE Mutations, and Insulin Resistance to Fibrosis in Nonalcoholic Fatty Liver
-
DOI 10.1002/hep.20023
-
Bugianesi, E., P. Manzini, S. D'Antico, E. Vanni, F. Longo, N. Leone, P. Massarenti, A. Piga, G. Marchesini, and M. Rizzetto. 2004. Relative contribution of iron burden, HFE mutations, and insulin resistance to fibrosis in nonalcoholic fatty liver. Hepatology. 39: 179-187. (Pubitemid 38461480)
-
(2004)
Hepatology
, vol.39
, Issue.1
, pp. 179-187
-
-
Bugianesi, E.1
Manzini, P.2
D'Antico, S.3
Vanni, E.4
Longo, F.5
Leone, N.6
Massarenti, P.7
Piga, A.8
Marchesini, G.9
Rizzetto, M.10
-
269
-
-
67649390890
-
Clinical practice. Alpha1-antitrypsin deficiency
-
Silverman, E. K., and R. A. Sandhaus. 2009. Clinical practice. Alpha1-antitrypsin deficiency. N. Engl. J. Med. 360: 2749-2757.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 2749-2757
-
-
Silverman, E.K.1
Sandhaus, R.A.2
-
270
-
-
33750622941
-
Alpha1-antitrypsin mutations in NAFLD: High prevalence and association with altered iron metabolism but not with liver damage
-
DOI 10.1002/hep.21329
-
Valenti, L., P. Dongiovanni, A. Piperno, A. L. Fracanzani, M. Maggioni, R. Rametta, P. Loria, M. A. Casiraghi, E. Suigo, R. Ceriani, et al. 2006. Alpha 1-antitrypsin mutations in NAFLD: high prevalence and association with altered iron metabolism but not with liver damage. Hepatology. 44: 857-864. (Pubitemid 46489549)
-
(2006)
Hepatology
, vol.44
, Issue.4
, pp. 857-864
-
-
Valenti, L.1
Dongiovanni, P.2
Piperno, A.3
Fracanzani, A.L.4
Maggioni, M.5
Rametta, R.6
Loria, P.7
Casiraghi, M.A.8
Suigo, E.9
Ceriani, R.10
Remondini, E.11
Trombini, P.12
Fargion, S.13
-
271
-
-
33745764351
-
Does the heterozygous state of alpha-1 antitrypsin deficiency have a role in chronic liver diseases? Interim results of a large casecontrol study
-
Regev, A., C. Guaqueta, E. G. Molina, A. Conrad, V. Mishra, M. L. Brantly, M. Torres, M. De Medina, A. G. Tzakis, and E. R. Schiff. 2006. Does the heterozygous state of alpha-1 antitrypsin deficiency have a role in chronic liver diseases? Interim results of a large casecontrol study. J. Pediatr. Gastroenterol. Nutr. 43 ( Suppl 1 ): S30-S35.
-
(2006)
J. Pediatr. Gastroenterol. Nutr.
, vol.43
, Issue.SUPPL. 1
-
-
Regev, A.1
Guaqueta, C.2
Molina, E.G.3
Conrad, A.4
Mishra, V.5
Brantly, M.L.6
Torres, M.7
De Medina, M.8
Tzakis, A.G.9
Schiff, E.R.10
-
272
-
-
55949120786
-
Variability and function of family 1 uridine-5′-diphosphate glucuronosyltransferases (UGT1A)
-
Strassburg, C. P., S. Kalthoff, and U. Ehmer. 2008. Variability and function of family 1 uridine-5′-diphosphate glucuronosyltransferases (UGT1A). Crit. Rev. Clin. Lab. Sci. 45: 485-530.
-
(2008)
Crit. Rev. Clin. Lab. Sci.
, vol.45
, pp. 485-530
-
-
Strassburg, C.P.1
Kalthoff, S.2
Ehmer, U.3
-
273
-
-
71949122207
-
Variants in the UGT1A1 gene and the risk of pediatric nonalcoholic fatty liver disease
-
Lin, Y. C., P. F. Chang, F. C. Hu, M. H. Chang, and Y. H. Ni. 2009. Variants in the UGT1A1 gene and the risk of pediatric nonalcoholic fatty liver disease. Pediatrics. 124: e1221-e1227.
-
(2009)
Pediatrics
, vol.124
-
-
Lin, Y.C.1
Chang, P.F.2
Hu, F.C.3
Chang, M.H.4
Ni, Y.H.5
-
274
-
-
17544368685
-
Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
-
Leslie, E. M., R. G. Deeley, and S. P. Cole. 2005. Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol. Appl. Pharmacol. 204: 216-237.
-
(2005)
Toxicol. Appl. Pharmacol.
, vol.204
, pp. 216-237
-
-
Leslie, E.M.1
Deeley, R.G.2
Cole, S.P.3
-
275
-
-
34248547635
-
MRP2 haplotypes confer differential susceptibility to toxic liver injury
-
Choi, J. H., B. M. Ahn, J. Yi, J. H. Lee, S. W. Nam, C. Y. Chon, K. H. Han, S. H. Ahn, I. J. Jang, J. Y. Cho, et al. 2007. MRP2 haplotypes confer differential susceptibility to toxic liver injury. Pharmacogenet. Genomics. 17: 403-415.
-
(2007)
Pharmacogenet. Genomics.
, vol.17
, pp. 403-415
-
-
Choi, J.H.1
Ahn, B.M.2
Yi, J.3
Lee, J.H.4
Nam, S.W.5
Chon, C.Y.6
Han, K.H.7
Ahn, S.H.8
Jang, I.J.9
Cho, J.Y.10
-
276
-
-
9344262376
-
Bile secretory function in the obese Zucker rat: Evidence of cholestasis and altered canalicular transport function
-
DOI 10.1136/gut.2003.037689
-
Pizarro, M., N. Balasubramaniyan, N. Solis, A. Solar, I. Duarte, J. F. Miquel, F. J. Suchy, M. Trauner, L. Accatino, M. Ananthanarayanan, et al. 2004. Bile secretory function in the obese Zucker rat: evidence of cholestasis and altered canalicular transport function. Gut. 53: 1837-1843. (Pubitemid 39556907)
-
(2004)
Gut
, vol.53
, Issue.12
, pp. 1837-1843
-
-
Pizarro, M.1
Balasubramaniyan, N.2
Solis, N.3
Solar, A.4
Duarte, I.5
Miquel, J.F.6
Suchy, F.J.7
Trauner, M.8
Accatino, L.9
Ananthanarayanan, M.10
Arrese, M.11
-
277
-
-
69749107591
-
Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease
-
Sookoian, S., G. Castano, T. F. Gianotti, C. Gemma, and C. J. Pirola. 2009. Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease. J. Nutr. Biochem. 20: 765-770.
-
(2009)
J. Nutr. Biochem.
, vol.20
, pp. 765-770
-
-
Sookoian, S.1
Castano, G.2
Gianotti, T.F.3
Gemma, C.4
Pirola, C.J.5
-
278
-
-
33745901941
-
Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver
-
DOI 10.1002/hep.21214
-
Meier, Y., C. Pauli-Magnus, U. M. Zanger, K. Klein, E. Schaeffeler, A. K. Nussler, N. Nussler, M. Eichelbaum, P. J. Meier, and B. Stieger. 2006. Interindividual variability of canalicular ATPbinding- cassette (ABC)-transporter expression in human liver. Hepatology. 44: 62-74. (Pubitemid 44049139)
-
(2006)
Hepatology
, vol.44
, Issue.1
, pp. 62-74
-
-
Meier, Y.1
Pauli-Magnus, C.2
Zanger, U.M.3
Klein, K.4
Schaeffeler, E.5
Nussler, A.K.6
Nussler, N.7
Eichelbaum, M.8
Meier, P.J.9
Stieger, B.10
-
279
-
-
33745204406
-
Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis
-
Nabeshima, Y., S. Tazuma, K. Kanno, H. Hyogo, M. Iwai, M. Horiuchi, and K. Chayama. 2006. Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis. Biochem. Biophys. Res. Commun. 346: 658-664.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.346
, pp. 658-664
-
-
Nabeshima, Y.1
Tazuma, S.2
Kanno, K.3
Hyogo, H.4
Iwai, M.5
Horiuchi, M.6
Chayama, K.7
-
280
-
-
34250323865
-
Angiotensin II type 1 receptor blocker inhibits fibrosis in rat nonalcoholic steatohepatitis
-
DOI 10.1002/hep.21638
-
Hirose, A., M. Ono, T. Saibara, Y. Nozaki, K. Masuda, A. Yoshioka, M. Takahashi, N. Akisawa, S. Iwasaki, J. A. Oben, et al. 2007. Angiotensin II type 1 receptor blocker inhibits fibrosis in rat nonalcoholic steatohepatitis. Hepatology. 45: 1375-1381. (Pubitemid 46918321)
-
(2007)
Hepatology
, vol.45
, Issue.6
, pp. 1375-1381
-
-
Hirose, A.1
Ono, M.2
Saibara, T.3
Nozaki, Y.4
Masuda, K.5
Yoshioka, A.6
Takahashi, M.7
Akisawa, N.8
Iwasaki, S.9
Oben, J.A.10
Onishi, S.11
-
281
-
-
34250360749
-
Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis
-
Ibanez, P., N. Solis, M. Pizarro, G. Aguayo, I. Duarte, J. F. Miquel, L. Accatino, and M. Arrese. 2007. Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis. J. Gastroenterol. Hepatol. 22: 846-851.
-
(2007)
J. Gastroenterol. Hepatol.
, vol.22
, pp. 846-851
-
-
Ibanez, P.1
Solis, N.2
Pizarro, M.3
Aguayo, G.4
Duarte, I.5
Miquel, J.F.6
Accatino, L.7
Arrese, M.8
-
282
-
-
7044222556
-
Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis
-
DOI 10.1002/hep.20420
-
Yokohama, S., M. Yoneda, M. Haneda, S. Okamoto, M. Okada, K. Aso, T. Hasegawa, Y. Tokusashi, N. Miyokawa, and K. Nakamura. 2004. Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis. Hepatology. 40: 1222-1225. (Pubitemid 39425579)
-
(2004)
Hepatology
, vol.40
, Issue.5
, pp. 1222-1225
-
-
Yokohama, S.1
Yoneda, M.2
Haneda, M.3
Okamoto, S.4
Okada, M.5
Aso, K.6
Hasegawa, T.7
Tokusashi, Y.8
Miyokawa, N.9
Nakamura, K.10
-
283
-
-
0034120267
-
Angiotensin II induces contraction and proliferation of human hepatic stellate cells
-
Bataller, R., P. Gines, J. M. Nicolas, M. N. Gorbig, E. Garcia- Ramallo, X. Gasull, J. Bosch, V. Arroyo, and J. Rodes. 2000. Angiotensin II induces contraction and proliferation of human hepatic stellate cells. Gastroenterology. 118: 1149-1156. (Pubitemid 30346992)
-
(2000)
Gastroenterology
, vol.118
, Issue.6
, pp. 1149-1156
-
-
Bataller, R.1
Gines, P.2
Nicolas, J.M.3
Gorbig, M.N.4
GarciaRamallo, E.5
Gasull, X.6
Bosch, J.7
Arroyo, V.8
Rodes, J.9
-
284
-
-
0034802566
-
Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats
-
DOI 10.1053/jhep.2001.28231
-
Yoshiji, H., S. Kuriyama, J. Yoshii, Y. Ikenaka, R. Noguchi, T. Nakatani, H. Tsujinoue, and H. Fukui. 2001. Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats. Hepatology. 34: 745-750. (Pubitemid 32927999)
-
(2001)
Hepatology
, vol.34
, Issue.4 I
, pp. 745-750
-
-
Yoshiji, H.1
Kuriyama, S.2
Yoshii, J.3
Ikenaka, Y.4
Noguchi, R.5
Nakatani, T.6
Tsujinoue, H.7
Fukui, H.8
-
285
-
-
16844374196
-
A1166C angiotensin II type 1 receptor gene polymorphism may predict hemodynamic response to losartan in patients with cirrhosis and portal hypertension
-
Sookoian, S., G. Castano, S. I. Garcia, P. Viudez, C. Gonzalez, and C. J. Pirola. 2005. A1166C angiotensin II type 1 receptor gene polymorphism may predict hemodynamic response to losartan in patients with cirrhosis and portal hypertension. Am. J. Gastroenterol. 100: 636-642.
-
(2005)
Am. J. Gastroenterol.
, vol.100
, pp. 636-642
-
-
Sookoian, S.1
Castano, G.2
Garcia, S.I.3
Viudez, P.4
Gonzalez, C.5
Pirola, C.J.6
-
286
-
-
67650504250
-
Association between angiotensin II type 1 receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease
-
Yoneda, M., K. Hotta, Y. Nozaki, H. Endo, T. Uchiyama, H. Mawatari, H. Iida, S. Kato, K. Fujita, H. Takahashi, et al. 2009. Association between angiotensin II type 1 receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease. Liver Int. 29: 1078-1085.
-
(2009)
Liver Int.
, vol.29
, pp. 1078-1085
-
-
Yoneda, M.1
Hotta, K.2
Nozaki, Y.3
Endo, H.4
Uchiyama, T.5
Mawatari, H.6
Iida, H.7
Kato, S.8
Fujita, K.9
Takahashi, H.10
|