The influence of the adiponectin gene on adiponectin concentrations and parameters of metabolic syndrome in non-diabetic Korean women

Clinica Chimica Acta

Volumn 391, Issue 1-2, 2008, Pages 85-90

  Jang, Yangsoo ^a,b,c   Chae, Jey Sook ^c   Koh, Soo Jeong ^c   Hyun, Yae Jung ^c   Kim, Ji Young ^c   Jeong, Yeo Jin ^c   Park, Sungha ^b   Ahn, Chul Min ^b   Lee, Jong Ho ^c  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Yonsei University   (South Korea)

Author keywords

Adipocyte C1q and collagen domain containing (ADIPOQ); Adiponectin; Homeostasis model assessment of insulin resistance (HOMA IR); Insulin; Single nucleotide polymorphism (SNP)

Indexed keywords

ADIPONECTIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; INSULIN RESISTANCE; KOREA; MAJOR CLINICAL STUDY; METABOLIC PARAMETERS; METABOLIC SYNDROME X; OBESITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADIPONECTIN; ADULT; AGED; FEMALE; GENOTYPE; HAPLOTYPES; HUMANS; INSULIN; KOREA; METABOLIC SYNDROME X; MIDDLE AGED; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; TRIGLYCERIDES;

EID: 41849104107     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2008.02.011     Document Type: Article

References (20)

1. Fumeron F., Aubert R., Siddiq A., et al. Epidemiologic Data on the Insulin Resistance Syndrome (DESIR) Study Group. Adiponectin gene polymorphisms and adiponectin concentrations are independently associated with the development of hyperglycemia during a 3-year period: the epidemiologic data on the insulin resistance syndrome prospective study. Diabetes 53 (2004) 1150-1157
2. Lindsay R.S., Funahashi T., Hanson R.L., et al. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet 360 (2002) 57-58
3. Spranger J., Kroke A., Möhlig M., et al. Adiponectin and protection against type 2 diabetes mellitus. Lancet 361 (2003) 226-228
4. Menzaghi C., Ercolino T., Di Paola R., et al. A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes 51 (2002) 2306-2312
5. Nakatani K., Noma K., Nishioka J., et al. Adiponectin gene variation associates with the increasing risk of type 2 diabetes in non-diabetic Japanese subjects. Int J Mol Med 15 (2005) 173-177
6. Vasseur F., Helbecque N., Dina C., et al. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone concentrations and contribute to the genetic risk for type 2 diabetes in French Caucasians. Hum Mol Genet 11 (2002) 2607-2614
7. Matthews D.R., Hosker J.P., Rudenski A.S., et al. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
8. Barrett J.C., Fry B., Maller J., and Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21 (2005) 263-265
9. Jang Y., Lee J.H., Chae J.S., et al. Association of the 276G→T polymorphism of the adiponectin gene with cardiovascular disease risk factors in nondiabetic Koreans. Am J Clin Nutr. 82 (2005) 760-767
10. Hara K., Boutin P., Mori Y., et al. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 51 (2002) 536-540
11. Mackevics V., Heid I.M., Wagner S.A., et al. The adiponectin gene is associated with adiponectin concentrations but not with characteristics of the insulin resistance syndrome in healthy Caucasians. Eur J Human Genet 16 (2006) 349-356
12. Ercolino T., Salvemini L., Coco A., et al. Multigenic control of serum adiponectin concentrations: evidence for a role of the APM1 gene and a locus on 14q13. Physiol Genomics 19 (2004) 170-174
13. Tankó L.B., Siddiq A., Lecoeur C., et al. ADIPOQ/Adiponectin and PPAR-Υ Gene Polymorphisms: Implications for Features of Obesity. Obes Res 13 (2005) 2113-2121
14. Helbecque N., Dina C., Lobbens S., et al. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocype-secreated adiponectin hormone concentrations and contribute to the genetic risk for type2 diabetes in French Caucasians. Hum Mol Genet 11 (2002) 2607-2614
15. Vasseur F., Helbecque N., Dina C., et al. Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ADIPOQ) gene promoter variants in morbid obesity: evidence for a role of ADIPOQ in diabesity. Diabetologia 48 (2005) 892-899
16. Tso A.W., Sham P.C., Wat N.M., et al. Polymorphisms of the gene encoding adiponectin and glycaemic outcome of Chinese subjects with impaired glucose tolerance: a 5-year follow-up study. Diabetologia 49 (2006) 1806-1815
17. Fruebis J., Tsao T.S., Javorschi S., et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci U S A 98 (2001) 2005-2010
18. Berg A.H., Combs T.P., Du X., Brownlee M., and Scherer P.E. The adipocyte-secreted protein Acrp30 enhances hepatic insulin actin. Nat Med 7 (2001) 947-953
19. Yamauchi T., Kamon J., Waki H., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7 (2001) 941-946
20. Filippi E., Sentinelli F., Trischitta V., Romeo S., Arca M., and Leonetti F. Association of the human adiponectin gene and insulin resistance. Eur J Human Genet 12 (2003) 199-205