A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes

Diabetologia

Volumn 45, Issue 5, 2002, Pages 740-743

  Hara, K ^a,d   Tobe, K ^a,d   Okada, T ^a,d   Kadowaki, H ^c,d   Akanuma, Y ^b,d   Ito, C ^d,e   Kimura, S ^a,d   Kadowaki, T ^a,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c INSTITUTE FOR ADULT DISEASES   (Japan)

^d NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^e Health Management and Promotion Center   (Japan)

Author keywords

Association study; Direct sequencing; Haplotype; HOMA; Linkage disequilibrium; PCR RFLP; Single nucleotide polymorphism; Susceptibility gene; Transcriptional coactivator

Indexed keywords

INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; GLYCOSYLATED HEMOGLOBIN; HEAT SHOCK PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1; PEROXISOME-PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA COACTIVATOR-1; PRIMER DNA; TRANSCRIPTION FACTOR;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE; CAUCASIAN; COMPARATIVE STUDY; GENETIC PREDISPOSITION; GENETICS; JAPAN; MIDDLE AGED; REFERENCE VALUE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

BASE SEQUENCE; CAUCASOID RACE; COMPARATIVE STUDY; DIABETES MELLITUS, NON-INSULIN-DEPENDENT; DNA PRIMERS; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HEAT-SHOCK PROTEINS; HEMOGLOBIN A, GLYCOSYLATED; HUMAN; INSULIN RESISTANCE; JAPAN; MIDDLE AGE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; REFERENCE VALUES; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION FACTORS; VARIATION (GENETICS); DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; HUMANS; MIDDLE AGED;

EID: 0035985096     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-002-0803-z     Document Type: Article

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