메뉴 건너뛰기




Volumn 38, Issue 4, 2008, Pages 254-258

The HFE gene heterozygosis H63D: A cofactor for liver damage in patients with steatohepatitis? Epidemiological and clinical considerations

Author keywords

H63D mutation; Haemochromatosis; Iron; Liver histology; Non alcoholic; Steatohepatitis

Indexed keywords

HFE PROTEIN; IRON;

EID: 41549138894     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/j.1445-5994.2007.01474.x     Document Type: Article
Times cited : (9)

References (20)
  • 2
    • 0034831067 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis
    • Reid AE. Nonalcoholic steatohepatitis. Gastroenterology 2001 121 : 710 23.
    • (2001) Gastroenterology , vol.121 , pp. 710-23
    • Reid, A.E.1
  • 3
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediator of hepatic steatosis and liver injury
    • Browning JD, Horton JD. Molecular mediator of hepatic steatosis and liver injury. J CIin Invest 2004 114 : 147 52.
    • (2004) J CIin Invest , vol.114 , pp. 147-52
    • Browning, J.D.1    Horton, J.D.2
  • 5
    • 2542560427 scopus 로고    scopus 로고
    • Hereditary haemochromatosis. a new look at an old disease
    • Pietrangelo A. Hereditary haemochromatosis. A new look at an old disease. N Engl J Med 2004 350 : 2383 97.
    • (2004) N Engl J Med , vol.350 , pp. 2383-97
    • Pietrangelo, A.1
  • 7
    • 0036291809 scopus 로고    scopus 로고
    • HFE mutations, hepatic iron, and fibrosis: Ethnic-specific association of NASH with C282Y but not with fibrotic severity
    • Chitturi S, Weltman M, Farrel CG, McDonald D, Kench J, Liddle C et al. HFE mutations, hepatic iron, and fibrosis: ethnic-specific association of NASH with C282Y but not with fibrotic severity. Hepatology 2002 36 : 142 9.
    • (2002) Hepatology , vol.36 , pp. 142-9
    • Chitturi, S.1    Weltman, M.2    Farrel, C.G.3    McDonald, D.4    Kench, J.5    Liddle, C.6
  • 8
    • 0033198317 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis and iron: Increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis
    • Bonkovsky HL, Jawaid O, Tortorelli K, Leclair P, Cobb J. Non-alcoholic steatohepatitis and iron: increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis. J Hepatol 1999 31 : 421 9.
    • (1999) J Hepatol , vol.31 , pp. 421-9
    • Bonkovsky, H.L.1    Jawaid, O.2    Tortorelli, K.3    Leclair, P.4    Cobb, J.5
  • 13
    • 0036107538 scopus 로고    scopus 로고
    • Frequency of the S65C mutation of HFE and iron overload in 309 subjects heterozygous for C282Y
    • Wallace DF, Walker AP, Pietrangelo A, Clare M, Bomford AB, Dixon JL et al. Frequency of the S65C mutation of HFE and iron overload in 309 subjects heterozygous for C282Y. J Hepatol 2002 36 : 474 9.
    • (2002) J Hepatol , vol.36 , pp. 474-9
    • Wallace, D.F.1    Walker, A.P.2    Pietrangelo, A.3    Clare, M.4    Bomford, A.B.5    Dixon, J.L.6
  • 14
    • 0032861319 scopus 로고    scopus 로고
    • The haemochromatosis gene: A co-factor for chronic liver diseases?
    • George DK, Powell LW, Losowsky MS. The haemochromatosis gene: a co-factor for chronic liver diseases? J Gastroenterol Hepatol 1999 14 : 745 9.
    • (1999) J Gastroenterol Hepatol , vol.14 , pp. 745-9
    • George, D.K.1    Powell, L.W.2    Losowsky, M.S.3
  • 15
    • 0036155984 scopus 로고    scopus 로고
    • The role of iron and haemochromatosis gene mutations in the progression of liver disease in chronic hepatitis C
    • Thorburn D, Curry E, Spooner R, Spence E, Oien K, Hallas D et al. The role of iron and haemochromatosis gene mutations in the progression of liver disease in chronic hepatitis C. Gut 2002 50 : 249 52.
    • (2002) Gut , vol.50 , pp. 249-52
    • Thorburn, D.1    Curry, E.2    Spooner, R.3    Spence, E.4    Oien, K.5    Hallas, D.6
  • 16
    • 0041808770 scopus 로고    scopus 로고
    • Mechanism of iron toxicity
    • Pietrangelo A. Mechanism of iron toxicity. Adv Exp Med Biol 2002 509 : 19 43.
    • (2002) Adv Exp Med Biol , vol.509 , pp. 19-43
    • Pietrangelo, A.1
  • 17
    • 33644802260 scopus 로고    scopus 로고
    • The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary haemochromatosis
    • Adams LA, Angulo P, Abraham SC, Torgerson H, Brandhagen D. The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary haemochromatosis. Liver Intern 2006 26 : 298 304.
    • (2006) Liver Intern , vol.26 , pp. 298-304
    • Adams, L.A.1    Angulo, P.2    Abraham, S.C.3    Torgerson, H.4    Brandhagen, D.5
  • 18
    • 33744913256 scopus 로고    scopus 로고
    • Iron and glucose homeostasis: New lessons from hereditary haemochromatosis
    • Wilson JG. Iron and glucose homeostasis: new lessons from hereditary haemochromatosis. Diabetologia 2006 49 : 1459 61.
    • (2006) Diabetologia , vol.49 , pp. 1459-61
    • Wilson, J.G.1
  • 19
    • 0029075197 scopus 로고
    • Inhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-L1 adipocytes
    • Shepherd PR, Soos MA, Siddle K. Inhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-L1 adipocytes. Biochem Biophys Res Commun 1995 211 : 535 9.
    • (1995) Biochem Biophys Res Commun , vol.211 , pp. 535-9
    • Shepherd, P.R.1    Soos, M.A.2    Siddle, K.3
  • 20
    • 0032555601 scopus 로고    scopus 로고
    • Co-trafficking of HFE, a neoclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation
    • Gross CN, Irrinki A, Feder JN, Enns CA. Co-trafficking of HFE, a neoclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation. J Biol Chem 1998 273 : 168 74.
    • (1998) J Biol Chem , vol.273 , pp. 168-74
    • Gross, C.N.1    Irrinki, A.2    Feder, J.N.3    Enns, C.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.