SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease

International Journal of Molecular Medicine

Volumn 21, Issue 4, 2008, Pages 507-511

  Kohjima, Motoyuki ^a   Higuchi, Nobito ^a   Kato, Masaki ^a   Kotoh, Kazuhiro ^a   Yoshimoto, Tsuyoshi ^b   Fujino, Tatsuya ^b   Yada, Masayoshi ^a   Yada, Ryoko ^b   Harada, Naohiko ^b   Enjoji, Munechika ^a   Takayanagi, Ryoichi ^a   Nakamuta, Makoto ^b  

^a KYUSHU UNIVERSITY   (Japan)

^b NATIONAL HOSPITAL ORGANIZATION   (Japan)

Author keywords

AMP activated protein kinase; Fatty acid; Forkhead box protein A2; Insulin receptor substrate; Nonalcoholic fatty liver disease; Sterol regulatory element binding protein 1c

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 3BETA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; AMP ACTIVATED PROTEIN KINASES; AMP-ACTIVATED PROTEIN KINASES; FAS ANTIGEN; FAS PROTEIN, HUMAN; FATTY ACID; FOXA2 PROTEIN, HUMAN; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE 2 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-2 PROTEIN; MULTIENZYME COMPLEX; PHOSPHOPROTEIN; PRIMER DNA; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SREBF1 PROTEIN, HUMAN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIVER CELL; NEGATIVE FEEDBACK; NONALCOHOLIC FATTY LIVER; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; BIOLOGICAL MODEL; CASE CONTROL STUDY; FATTY LIVER; FEEDBACK SYSTEM; GENETICS; LIVER; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIGENS, CD95; BASE SEQUENCE; CASE-CONTROL STUDIES; DNA PRIMERS; FATTY ACIDS; FATTY LIVER; FEEDBACK; GENE EXPRESSION; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HUMANS; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 44649111219     PISSN: 11073756     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijmm.21.4.507     Document Type: Article

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