Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways

Cell Biology International

Volumn 33, Issue 12, 2009, Pages 1237-1244

  Ouyang, Gaoliang ^a   Yao, Luming ^a   Ruan, Kai ^a   Song, Gang ^a,b   Mao, Yubin ^a,b   Bao, Shideng ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b XIAMEN UNIVERSITY   (China)

Author keywords

Apoptosis; DNA damage checkpoint; Genistein; Ovarian cancer cell

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE 1; GENISTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE A; PROTEIN TYROSINE PHOSPHATASE C; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DRUG EXPOSURE; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INACTIVATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; OVARY CANCER; PHASE CONTRAST MICROSCOPY; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANTICARCINOGENIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BRCA1 PROTEIN; CDC25 PHOSPHATASES; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN B; DNA DAMAGE; DNA-BINDING PROTEINS; FEMALE; GENISTEIN; HUMANS; OVARIAN NEOPLASMS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

GLYCINE MAX;

EID: 71549153495     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2009.08.011     Document Type: Article

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