Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-κB activation, IκB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells

Oncogene

Volumn 17, Issue 7, 1998, Pages 913-918

  Kumar, Ashok ^a   Dhawair, Subhash ^b   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Adhesion; Emodin; Endothelial cells; I B ; NF B; TNF

Indexed keywords

CELL ADHESION MOLECULE; CYTOKINE; EMODIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN SUBUNIT; TUMOR NECROSIS FACTOR; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BINDING SITE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE; MONOCYTE; PLANT ROOT; PRIORITY JOURNAL; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

POLYGONUM CUSPIDATUM;

EID: 15444356379     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1201998     Document Type: Article

References (26)

1. Aggarwal BB and Natarajan K. (1996). Eur. Cytokine Netw., 7, 93-124.
2. Baeuerle PA and Baichwal VR. (1997). Adv. Immunol., 65, 111-137.
3. Baichwal VR and Baeuerle PA. (1997). Curr. Biol., 7, R94-R96.
4. Carlos TM and Harlan JM. (1994). Blood, 84, 2068-2101.
5. Chan TC, Chang CJ, Koonchanok NM and Geahlen RL. (1993). Biochem. Biophy. Res. Commun., 193, 1152-1158.
6. Chaturvedi M, Kumar A, Darnay BG, Chainy GBN, Agarwal S and Aggarwal BB. (1997). J. Biol. Chem., 272, 30129-30134.
7. Dhawan S, Puri RK, Kumar A, Duplan H, Masson J-M and Aggarwal BB. (1997). Blood, 90, 1535-1544.
8. Fredenhagen A, Mett H, Meyer T, Buchdunger E, Regenass U, Roggo BE and Petersen F. (1995). J. Antibiotics, 48, 1355-1358.
9. Frew T, Powis G, Berggren M, Abraham RT, Ashendel CL, Zalkow LH, Hudson C, Qazia S, Gruszecka-Kowalik E, Merriman R and Bonjouklian R. (1994). Anticancer Res., 14, 2425-2428.
10. Hsu H, Shu H-B, Pan MP and Goeddel DV. (1996). Cell, 84, 299-308.
11. Huang HC, Chang JH, Tung SF, Wu RT, Foegh ML and Chu SH. (1992). Eur. J. Pharmacol., 211, 359-364.
12. Iademarco MF, McQuillan JJ, Rosen GD and Dean DC. (1992). J. Biol. Chem., 267, 16323-16329.
13. Jayasuriya H, Koonchanok NM, Geahlen RL, McLaughlin JL and Chang CJ. (1992). J. Natural Prod., 55, 696-698.
14. Kumar A, Dhawan S, Hardegen NJ and Agearwal BB. (1998). Biochem. Pharmacol., 55, 775-783.
15. Lin CC, Chang CH, Yang JJ, Namba T and Hattori M. (1996). J. Ethnopharmacol., 52, 107-111.
16. McCarty JM, Yee EK, Deisher TA, Harlan JM and Kaushansky K. (1995). FEBS Lett., 373, 194-198.
17. Natarajan K, Manna SK, Chaturvedi MM and Aggarwal BB. (1998). Arch. Biochem. Biophys. 352, 59-70.
18. Reddy SAG, Chaturvedi MM, Darnay BG, Chan H, Higuchi M and Aggarwal BB. (1994). J. Biol. Chem., 269, 25369-25372.
19. Singh S and Aggarwal BB. (1995). J. Biol. Chem., 270, 10631-10639.
20. Singh S, Darnay BG and Aggarwal BB. (1996). J. Biol. Chem., 271, 31049-31054.
21. Stancovski I and Baltimore D. (1997). Cell, 82, 299-302.
22. Schindler U and Baichwal VR. (1994). Mol. Cell Biol., 14, 5820-5831.
23. Springer TA. (1994). Cell, 76, 301-314.
24. Voraberger G, Schafer R and Stratowa C. (1991). J. Immunol., 147, 2777-2786.
25. Zhang L and Hung MC. (1996). Oncogene, 12, 571-576.
26. Zhang L, Chang CJ, Bacus SS and Hung MC. (1995). Cancer Res., 55, 3890-3896.