Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5

Cancer Research

Volumn 66, Issue 11, 2006, Pages 5867-5874

  Frese, Steffen ^a   Frese Schaper, Manuela ^a   Andres, Anne Catherine ^b   Miescher, Daniela ^a   Zumkehr, Beatrice ^a   Schmid, Ralph A ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BUFALIN; CARDIAC GLYCOSIDE; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DIGITOXIN; DIGOXIN; LANATOSIDE C; MITOGEN ACTIVATED PROTEIN KINASE; OLEANDRIN; OUBAIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; ENZYME INHIBITION; HEART FAILURE; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; MINIMUM INHIBITORY CONCENTRATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SENSITIZATION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, NON-SMALL-CELL LUNG; CARDENOLIDES; CARDIAC GLYCOSIDES; CELL LINE, TUMOR; DRUG SYNERGISM; HUMANS; LUNG NEOPLASMS; MEMBRANE GLYCOPROTEINS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, SMALL INTERFERING; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 33745228422     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-3544     Document Type: Article

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