메뉴 건너뛰기




Volumn 148, Issue 8, 2006, Pages 1099-1107

Acetyl-keto-β-boswellic acid inhibits cellular proliferation through a p21-dependent pathway in colon cancer cells

Author keywords

Acetyl keto boswellic acid; Cell cycle; Colon cancer; Cyclin; Cyclin dependent kinase; p21; p53

Indexed keywords

ACETYL KETO BETA BOSWELLIC ACID; BOSWELLIC ACID; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; PHOSPHOPROTEIN; PHOSPHORYLATED RETINOBLASTOMA PROTEIN; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

EID: 33747099596     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706817     Document Type: Article
Times cited : (85)

References (34)
  • 2
    • 20144384882 scopus 로고    scopus 로고
    • Lost in transcription: P21 repression, mechanisms, and consequences
    • GARTEL, A.L. & RADHAKRISHNAN, S.K. (2005). Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Res., 65, 3980-3985.
    • (2005) Cancer Res. , vol.65 , pp. 3980-3985
    • Gartel, A.L.1    Radhakrishnan, S.K.2
  • 3
    • 0036594890 scopus 로고    scopus 로고
    • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
    • GARTEL, A.L. & TYNER, A.L. (2002). The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol. Cancer Ther., 1, 639-649.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 639-649
    • Gartel, A.L.1    Tyner, A.L.2
  • 6
    • 0032541951 scopus 로고    scopus 로고
    • Effects of Boswellia serrata gum resin in patients with bronchial asthma: Results of a double-blind, placebo-controlled, 6-week clinical study
    • GUPTA, I., GUPTA, V., PARIHAR, A., GUPTA, S., LUDTKE, R., SAFAYHI, H. & AMMON, H.P. (1998). Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur. J. Med. Res., 3, 511-514.
    • (1998) Eur. J. Med. Res. , vol.3 , pp. 511-514
    • Gupta, I.1    Gupta, V.2    Parihar, A.3    Gupta, S.4    Ludtke, R.5    Safayhi, H.6    Ammon, H.P.7
  • 9
    • 0027957893 scopus 로고
    • Highlight on the studies of anticancer drugs derived from plants in China
    • HAN, R. (1994a). Highlight on the studies of anticancer drugs derived from plants in China. Stem. Cells, 12, 53-63.
    • (1994) Stem. Cells , vol.12 , pp. 53-63
    • Han, R.1
  • 10
    • 0028086475 scopus 로고
    • Recent progress in the study of anticancer drugs originating from plants and traditional medicines in China
    • HAN, R. (1994b). Recent progress in the study of anticancer drugs originating from plants and traditional medicines in China. Chin. Med. Sci. J., 9, 61-69.
    • (1994) Chin. Med. Sci. J. , vol.9 , pp. 61-69
    • Han, R.1
  • 11
  • 13
    • 0034492409 scopus 로고    scopus 로고
    • Anti-tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid
    • HUANG, M.T., BADMAEV, V., DING, Y., LIU, Y., XIE, J.G. & HO, C.T. (2000). Anti-tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid. Biofactors, 13, 225-230.
    • (2000) Biofactors , vol.13 , pp. 225-230
    • Huang, M.T.1    Badmaev, V.2    Ding, Y.3    Liu, Y.4    Xie, J.G.5    Ho, C.T.6
  • 14
    • 0027938209 scopus 로고
    • Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age
    • HUNTER, T. & PINES, J. (1994). Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell, 79, 573-582.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 15
    • 0033843434 scopus 로고    scopus 로고
    • Boswellic acids in the palliative therapy of children with progressive or relapsed brain tumors
    • JANSSEN, G., BODE, U., BREU, H., DOHRN, B., ENGELBRECHT, V. & GOBEL, U. (2000). Boswellic acids in the palliative therapy of children with progressive or relapsed brain tumors. Klin. Padiatr., 212, 189-195.
    • (2000) Klin. Padiatr. , vol.212 , pp. 189-195
    • Janssen, G.1    Bode, U.2    Breu, H.3    Dohrn, B.4    Engelbrecht, V.5    Gobel, U.6
  • 16
    • 0032890058 scopus 로고    scopus 로고
    • Boswellic acid acetate induces differentiation and apoptosis in leukemia cell lines
    • JING, Y., NAKAJO, S., XIA, L., NAKAYA, K., FANG, Q., WAXMAN, S. & HAN, R. (1999). Boswellic acid acetate induces differentiation and apoptosis in leukemia cell lines. Leuk. Res., 23, 43-50.
    • (1999) Leuk. Res. , vol.23 , pp. 43-50
    • Jing, Y.1    Nakajo, S.2    Xia, L.3    Nakaya, K.4    Fang, Q.5    Waxman, S.6    Han, R.7
  • 18
    • 24744462701 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells
    • LE, H.V., MINN, A.J. & MASSAGUE, J. (2005). Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells. J. Biol. Chem., 280, 32018-32025.
    • (2005) J. Biol. Chem. , vol.280 , pp. 32018-32025
    • Le, H.V.1    Minn, A.J.2    Massague, J.3
  • 19
    • 0036780654 scopus 로고    scopus 로고
    • Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway
    • LIU, J.J., NILSSON, A., OREDSSON, S., BADMAEV, V. & DUAN, R.D. (2002a). Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway. Int. J. Mol. Med., 10, 501-505.
    • (2002) Int. J. Mol. Med. , vol.10 , pp. 501-505
    • Liu, J.J.1    Nilsson, A.2    Oredsson, S.3    Badmaev, V.4    Duan, R.D.5
  • 20
    • 0036949876 scopus 로고    scopus 로고
    • Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells
    • LIU, J.J., NILSSON, A., OREDSSON, S., BADMAEV, V., ZHAO, W.Z. & DUAN, R.D. (2002b). Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis, 23, 2087-2093.
    • (2002) Carcinogenesis , vol.23 , pp. 2087-2093
    • Liu, J.J.1    Nilsson, A.2    Oredsson, S.3    Badmaev, V.4    Zhao, W.Z.5    Duan, R.D.6
  • 21
    • 3042739681 scopus 로고    scopus 로고
    • Heparin/heparan sulfate interacting protein plays a role in apoptosis induced by anticancer drugs
    • LIU, J.J., ZHANG, J., RAMANAN, S., JULIAN, J., CARSON, D.D. & HOOI, S.C. (2004). Heparin/heparan sulfate interacting protein plays a role in apoptosis induced by anticancer drugs. Carcinogenesis, 25, 873-879.
    • (2004) Carcinogenesis , vol.25 , pp. 873-879
    • Liu, J.J.1    Zhang, J.2    Ramanan, S.3    Julian, J.4    Carson, D.D.5    Hooi, S.C.6
  • 22
    • 0035754080 scopus 로고    scopus 로고
    • To cycle or not to cycle: A critical decision in cancer
    • MALUMBRES, M. & BARBACID, M. (2001). To cycle or not to cycle: a critical decision in cancer. Nat. Rev. Cancer, 1, 222-231.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 222-231
    • Malumbres, M.1    Barbacid, M.2
  • 23
    • 0642317080 scopus 로고    scopus 로고
    • Regulation of the eukaryotic cell cycle
    • MCGOWAN, C.H. (2003). Regulation of the eukaryotic cell cycle. Prog. Cell. Cycle Res., 5, 1-4.
    • (2003) Prog. Cell. Cycle Res. , vol.5 , pp. 1-4
    • Mcgowan, C.H.1
  • 24
    • 0034964014 scopus 로고    scopus 로고
    • Retinoblastoma protein partners
    • MORRIS, E.J. & DYSON, N.J. (2001). Retinoblastoma protein partners. Adv. Cancer Res., 82, 1-54.
    • (2001) Adv. Cancer Res. , vol.82 , pp. 1-54
    • Morris, E.J.1    Dyson, N.J.2
  • 25
    • 0038784203 scopus 로고    scopus 로고
    • Acetyl-11-keto-beta-boswellic acid (AKBA) is cytotoxic for meningioma cells and inhibits phosphorylation of the extracellular-signal regulated kinase 1 and 2
    • PARK, Y.S., LEE, J.H., HARWALKAR, J.A., BONDAR, J., SAFAYHI, H. & GOLUBIC, M. (2002). Acetyl-11-keto-beta-boswellic acid (AKBA) is cytotoxic for meningioma cells and inhibits phosphorylation of the extracellular-signal regulated kinase 1 and 2. Adv. Exp. Med. Biol., 507, 387-393.
    • (2002) Adv. Exp. Med. Biol. , vol.507 , pp. 387-393
    • Park, Y.S.1    Lee, J.H.2    Harwalkar, J.A.3    Bondar, J.4    Safayhi, H.5    Golubic, M.6
  • 27
    • 0026030741 scopus 로고
    • Protection by boswellic acids against galactosamine/endotoxin-induced hepatitis in mice
    • SAFAYHI, H., MACK, T. & AMMON, H.P. (1991). Protection by boswellic acids against galactosamine/endotoxin-induced hepatitis in mice. Biochem. Pharmacol., 41, 1536-1537.
    • (1991) Biochem. Pharmacol. , vol.41 , pp. 1536-1537
    • Safayhi, H.1    Mack, T.2    Ammon, H.P.3
  • 28
    • 0031802980 scopus 로고    scopus 로고
    • Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cells in culture
    • SHAO, Y., HO, C.T., CHIN, C.K., BADMAEV, V., MA, W. & HUANG, M.T. (1998). Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cells in culture. Planta. Med., 64, 328-331.
    • (1998) Planta. Med. , vol.64 , pp. 328-331
    • Shao, Y.1    Ho, C.T.2    Chin, C.K.3    Badmaev, V.4    Ma, W.5    Huang, M.T.6
  • 29
    • 0024462668 scopus 로고
    • Anti-arthritic activity of boswellic acids in bovine serum albumin (BSA)-induced arthritis
    • SHARMA, M.L., BANI, S. & SINGH, G.B. (1989). Anti-arthritic activity of boswellic acids in bovine serum albumin (BSA)-induced arthritis. Int. J. Immunopharmacol., 11, 647-652.
    • (1989) Int. J. Immunopharmacol. , vol.11 , pp. 647-652
    • Sharma, M.L.1    Bani, S.2    Singh, G.B.3
  • 30
    • 0035826816 scopus 로고    scopus 로고
    • Response of radiochemotherapy-associated cerebral edema to a phytotherapeutic agent, H15
    • STREFFER, J.R., BITZER, M., SCHABET, M., DICHGANS, J. & WELLER, M. (2001). Response of radiochemotherapy-associated cerebral edema to a phytotherapeutic agent, H15. Neurology, 56, 1219-1221.
    • (2001) Neurology , vol.56 , pp. 1219-1221
    • Streffer, J.R.1    Bitzer, M.2    Schabet, M.3    Dichgans, J.4    Weller, M.5
  • 31
    • 14044268207 scopus 로고    scopus 로고
    • Inhibition of IkappaB kinase activity by acetyl-boswellic acids promotes apoptosis in androgen-independent PC-3 prostate cancer cells in vitro and in vivo
    • SYROVETS, T., GSCHWEND, J.E., BUCHELE, B., LAUMONNIER, Y., ZUGMAIER, W., GENZE, F. & SIMMET, T. (2005). Inhibition of IkappaB kinase activity by acetyl-boswellic acids promotes apoptosis in androgen-independent PC-3 prostate cancer cells in vitro and in vivo. J. Biol. Chem., 280, 6170-6180.
    • (2005) J. Biol. Chem. , vol.280 , pp. 6170-6180
    • Syrovets, T.1    Gschwend, J.E.2    Buchele, B.3    Laumonnier, Y.4    Zugmaier, W.5    Genze, F.6    Simmet, T.7
  • 34
    • 0242500941 scopus 로고    scopus 로고
    • Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells
    • ZHAO, W., ENTSCHLADEN, F., LIU, H., NIGGEMANN, B., FANG, Q., ZAENKER, K.S. & HAN, R. (2003). Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells. Cancer Detect. Prev., 27, 67-75.
    • (2003) Cancer Detect. Prev. , vol.27 , pp. 67-75
    • Zhao, W.1    Entschladen, F.2    Liu, H.3    Niggemann, B.4    Fang, Q.5    Zaenker, K.S.6    Han, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.