-
1
-
-
0031913246
-
Mechanism of activation and function of protein kinase B
-
Alessi DR, Cohen P: Mechanism of activation and function of protein kinase B. Curr. Opin. Genet. Dev. 8(1), 55-62 (1998).
-
(1998)
Curr. Opin. Genet. Dev.
, vol.8
, Issue.1
, pp. 55-62
-
-
Alessi, D.R.1
Cohen, P.2
-
2
-
-
6344222251
-
-
Dekker, Hamilton, ON, 5th Ed.
-
Schally AV, Comaru-Schally AM: in Cancer Medicine. Dekker, Hamilton, ON, 5th Ed., 715-729 (2000).
-
(2000)
Cancer Medicine
, pp. 715-729
-
-
Schally, A.V.1
Comaru-Schally, A.M.2
-
3
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL: Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235(4785), 177-182 (1987).
-
(1987)
Science
, vol.235
, Issue.4785
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
4
-
-
0242455889
-
Role of HER2 gene overexpression in breast carcinoma
-
Menard S, Tagliabue E, Campiglio M, Pupa SM: Role of HER2 gene overexpression in breast carcinoma. J. Cell Physiol. 182(2), 150-162 (2000).
-
(2000)
J. Cell Physiol.
, vol.182
, Issue.2
, pp. 150-162
-
-
Menard, S.1
Tagliabue, E.2
Campiglio, M.3
Pupa, S.M.4
-
5
-
-
0025940263
-
Expression of activated rat neu oncogene is sufficient to induce experimental metastasis in 3T3 cells
-
Yu DH, Hung MC: Expression of activated rat neu oncogene is sufficient to induce experimental metastasis in 3T3 cells. Oncogene 6(11), 1991-1996 (1991).
-
(1991)
Oncogene
, vol.6
, Issue.11
, pp. 1991-1996
-
-
Yu, D.H.1
Hung, M.C.2
-
6
-
-
0028278501
-
C-erbB-2/neu overexpression enhances metastatic potential of human lung cancer cells by induction of metastasis-associated properties
-
Yu DH, Wang SS, Dulski KM, Nicolson, GL, Hung MC: c-erbB-2/neu overexpression enhances metastatic potential of human lung cancer cells by induction of metastasis-associated properties. Cancer Res. 54(12), 3150-3156 (1994).
-
(1994)
Cancer Res.
, vol.54
, Issue.12
, pp. 3150-3156
-
-
Yu, D.H.1
Wang, S.S.2
Dulski, K.M.3
Nicolson, G.L.4
Hung, M.C.5
-
7
-
-
0025196092
-
Low metastatic potential of clone from murine colon adenocarcinoma 26 increased by transfection of activated c-erbB-2 gene
-
Yusa K, Sugimot Y, Yamori T, Yamamoto T, Toyoshima K, Tsuruo T: Low metastatic potential of clone from murine colon adenocarcinoma 26 increased by transfection of activated c-erbB-2 gene. J. Natl. Cancer Inst. 82(20), 1632-1635 (1990).
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, Issue.20
, pp. 1632-1635
-
-
Yusa, K.1
Sugimot, Y.2
Yamori, T.3
Yamamoto, T.4
Toyoshima, K.5
Tsuruo, T.6
-
9
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, Hynes NE: The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J. 19(13), 3159-3167 (2000).
-
(2000)
EMBO J.
, vol.19
, Issue.13
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
Hynes, N.E.4
-
10
-
-
0028168569
-
Insect cellexpressed p180erbB3 possesses an impaired tyrosine kinase activity
-
Guy PM, Platko JV, Cantley LC, Cerione RA, Carraway KL 3rd: Insect cellexpressed p180erbB3 possesses an impaired tyrosine kinase activity. Proc. Natl Acad. Sci. USA 91(17), 8132-8136 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, Issue.17
, pp. 8132-8136
-
-
Guy, P.M.1
Platko, J.V.2
Cantley, L.C.3
Cerione, R.A.4
Carraway III, K.L.5
-
11
-
-
0030973939
-
Biochemical characterization of the protein tyrosine kinase homology domain of the ErbB3 (HER3) receptor protein
-
Sierke SL, Cheng K, Kim HH, Koland JG.: Biochemical characterization of the protein tyrosine kinase homology domain of the ErbB3 (HER3) receptor protein. Biochem. J. 322(Pt3), 757-763 (1997).
-
(1997)
Biochem. J.
, vol.322
, Issue.PART 3
, pp. 757-763
-
-
Sierke, S.L.1
Cheng, K.2
Kim, H.H.3
Koland, J.G.4
-
12
-
-
0028077047
-
Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product
-
Kim HH, Sierke SL, Koland JG: Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product. J. Biol. Chem. 269(40), 24747-24755 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, Issue.40
, pp. 24747-24755
-
-
Kim, H.H.1
Sierke, S.L.2
Koland, J.G.3
-
13
-
-
0028302018
-
ErbB3 is involved in activation of phosphatidylinositol 3- kinase by epidermal growth factor
-
Soltoff SP, Carraway KL 3rd, Prigent SA, Gullick WG, Cantley LC: ErbB3 is involved in activation of phosphatidylinositol 3- kinase by epidermal growth factor. Mol. Cell. Biol. 14(6), 3550-3558 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, Issue.6
, pp. 3550-3558
-
-
Soltoff, S.P.1
Carraway III, K.L.2
Prigent, S.A.3
Gullick, W.G.4
Cantley, L.C.5
-
14
-
-
0029162564
-
Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3
-
Wallasch C, Weiss FU, Niederfellner G, Jallal B, Issing W, Ullrich A: Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3. EMBO J. 14(17), 4267-4275 (1995).
-
(1995)
EMBO J.
, vol.14
, Issue.17
, pp. 4267-4275
-
-
Wallasch, C.1
Weiss, F.U.2
Niederfellner, G.3
Jallal, B.4
Issing, W.5
Ullrich, A.6
-
15
-
-
0028358856
-
Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin
-
Sliwkowski MX, Schaefer G, Akita RW et al.: Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin. J. Biol. Chem. 269(20), 14661-14665 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, Issue.20
, pp. 14661-14665
-
-
Sliwkowski, M.X.1
Schaefer, G.2
Akita, R.W.3
-
16
-
-
0029783549
-
Neu differentiation factor neuregulin isoforms activate distinct receptor combinations
-
Pinkas-Kramarski R, Shelly M, Glathe S, Ratzkin BJ, Yarden Y: Neu differentiation factor neuregulin isoforms activate distinct receptor combinations. J. Biol. Chem. 271(32), 19029-19032 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.32
, pp. 19029-19032
-
-
Pinkas-Kramarski, R.1
Shelly, M.2
Glathe, S.3
Ratzkin, B.J.4
Yarden, Y.5
-
17
-
-
0028949081
-
Heregulin stimulates mitogenesis and phosphatidylinositol 3- kinase in mouse fibroblasts transfected with erbB2/neu and erbB3
-
Carraway KL 3rd, Soltoff SP, Diamonti AJ, Cantley LC: Heregulin stimulates mitogenesis and phosphatidylinositol 3- kinase in mouse fibroblasts transfected with erbB2/neu and erbB3. J. Biol. Chem. 270(13), 7111-7116 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.13
, pp. 7111-7116
-
-
Carraway III, K.L.1
Soltoff, S.P.2
Diamonti, A.J.3
Cantley, L.C.4
-
18
-
-
0029804204
-
The relationship between human epidermal growth factor-like receptor expression and cellular transformation in NIH 3T3 cells
-
Cohen BD, Kiener PA, Green JM, Foy L, Fell HP, Zhang K: The relationship between human epidermal growth factor-like receptor expression and cellular transformation in NIH 3T3 cells. J. Biol. Chem. 271(48), 30897-30903 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.48
, pp. 30897-30903
-
-
Cohen, B.D.1
Kiener, P.A.2
Green, J.M.3
Foy, L.4
Fell, H.P.5
Zhang, K.6
-
19
-
-
0030064531
-
Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2
-
Zhang K, Sun JL, Liu NL et al.: Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2. J. Biol. Chem. 271(7), 3884-3890 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.7
, pp. 3884-3890
-
-
Zhang, K.1
Sun, J.L.2
Liu, N.L.3
-
20
-
-
0029053716
-
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas
-
Alimandi M, Romano A, Curia MC et al.: Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene 10(9), 1813-1821 (1995).
-
(1995)
Oncogene
, vol.10
, Issue.9
, pp. 1813-1821
-
-
Alimandi, M.1
Romano, A.2
Curia, M.C.3
-
21
-
-
0033561296
-
Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: Implications for human breast cancer
-
Siegel PM, Siegel ED, Cardiff RD, Muller WJ: Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer. EMBO J. 18(8), 2149-2164 (1999).
-
(1999)
EMBO J.
, vol.18
, Issue.8
, pp. 2149-2164
-
-
Siegel, P.M.1
Siegel, E.D.2
Cardiff, R.D.3
Muller, W.J.4
-
22
-
-
33644875100
-
Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells
-
Kim A, Liu B, Ordonez-Ercan D et al.: Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells. Breast Cancer Res. 7(5), R708-R718 (2005).
-
(2005)
Breast Cancer Res.
, vol.7
, Issue.5
-
-
Kim, A.1
Liu, B.2
Ordonez-Ercan, D.3
-
23
-
-
1042289764
-
Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neuoverexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Aktdependent pathway
-
Way TD, Kao MC, Lin JK: Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neuoverexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Aktdependent pathway. J. Biol. Chem. 279(6), 4479-4489 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.6
, pp. 4479-4489
-
-
Way, T.D.1
Kao, M.C.2
Lin, J.K.3
-
24
-
-
0025605344
-
The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily
-
Aroian RV, Koga M, Mendel JE, Ohshima Y, Sternberg PW: The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily. Nature 348(6303), 693-699 (1990).
-
(1990)
Nature
, vol.348
, Issue.6303
, pp. 693-699
-
-
Aroian, R.V.1
Koga, M.2
Mendel, J.E.3
Ohshima, Y.4
Sternberg, P.W.5
-
25
-
-
0031659601
-
Complexity of EGF receptor signalling revealed in Drosophila
-
Freeman M: Complexity of EGF receptor signalling revealed in Drosophila. Curr. Opin. Genet. Dev. 8(4), 407-411 (1998).
-
(1998)
Curr. Opin. Genet. Dev.
, vol.8
, Issue.4
, pp. 407-411
-
-
Freeman, M.1
-
26
-
-
0032549036
-
The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: From orphanhood to multiple stromal ligands
-
Tzahar E, Yarden Y: The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: from orphanhood to multiple stromal ligands. Biochim. Biophys. Acta 1377(1), M25-M37 (1998).
-
(1998)
Biochim. Biophys. Acta
, vol.1377
, Issue.1
-
-
Tzahar, E.1
Yarden, Y.2
-
27
-
-
0034773992
-
The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities
-
Yarden Y: The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. Eur. J. Cancer 37(Suppl. 4), S3-S8 (2001).
-
(2001)
Eur. J. Cancer
, vol.37
, Issue.SUPPL. 4
-
-
Yarden, Y.1
-
28
-
-
0022647432
-
The product of the human cerbB-2 gene: A 185- kilodalton glycoprotein with tyrosine kinase activity
-
Akiyama T, Sudo C, Ogawara H, Toyoshima K, Yamamoto T: The product of the human cerbB-2 gene: a 185- kilodalton glycoprotein with tyrosine kinase activity. Science 232(4758), 1644-1646 (1986).
-
(1986)
Science
, vol.232
, Issue.4758
, pp. 1644-1646
-
-
Akiyama, T.1
Sudo, C.2
Ogawara, H.3
Toyoshima, K.4
Yamamoto, T.5
-
29
-
-
0028170817
-
Receptor protein-tyrosine kinases and their signal transduction pathways
-
van der Geer P, Hunter T, Lindberg RA: Receptor protein-tyrosine kinases and their signal transduction pathways. Ann. Rev. Cell Biol. 10, 251-337 (1994).
-
(1994)
Ann. Rev. Cell Biol.
, vol.10
, pp. 251-337
-
-
Van Der Geer, P.1
Hunter, T.2
Lindberg, R.A.3
-
30
-
-
0028670125
-
The biology of erbB-2/neu/HER-2 and its role in cancer
-
Hynes NE, Stern DF: The biology of erbB-2/neu/HER-2 and its role in cancer. Biochim. Biophys. Acta Rev. Cancer 1198(2-3), 165-184 (1994).
-
(1994)
Biochim. Biophys. Acta Rev. Cancer
, vol.1198
, Issue.2-3
, pp. 165-184
-
-
Hynes, N.E.1
Stern, D.F.2
-
31
-
-
0033947243
-
Evolutionary analysis of the ErbB receptor and ligand families
-
Stein RA, Staros JV: Evolutionary analysis of the ErbB receptor and ligand families. J. Mol. Evol. 50(5), 397-412 (2000).
-
(2000)
J. Mol. Evol.
, vol.50
, Issue.5
, pp. 397-412
-
-
Stein, R.A.1
Staros, J.V.2
-
32
-
-
0034869825
-
The basic biology of HER2
-
Rubin I, Yarden Y: The basic biology of HER2. Ann. Oncol. 12(Suppl. 1), S3-S8 (2001).
-
(2001)
Ann. Oncol.
, vol.12
, Issue.SUPPL. 1
-
-
Rubin, I.1
Yarden, Y.2
-
33
-
-
2142843806
-
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
-
Pinkas-Kramarski R, Soussan L, Waterman H et al.: Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J. 15(10), 2452-2467 (1996).
-
(1996)
EMBO J.
, vol.15
, Issue.10
, pp. 2452-2467
-
-
Pinkas-Kramarski, R.1
Soussan, L.2
Waterman, H.3
-
34
-
-
0033608993
-
The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors
-
Klapper LN, Glathe S, Vaisman N et al.: The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors. Proc. Natl Acad. Sci. USA 96(9), 4995-5000 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, Issue.9
, pp. 4995-5000
-
-
Klapper, L.N.1
Glathe, S.2
Vaisman, N.3
-
35
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
-
Graus-Porta D, Beerli RR, Daly JM, Hynes NE: ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J. 16(7), 1647-1655 (1997).
-
(1997)
EMBO J.
, vol.16
, Issue.7
, pp. 1647-1655
-
-
Graus-Porta, D.1
Beerli, R.R.2
Daly, J.M.3
Hynes, N.E.4
-
36
-
-
0031840484
-
ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner
-
Olayioye MA, Graus-Porta D, Beerli RR, Rohrer J, Gay B, Hynes NE: ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner. Mol. Cell Biol. 18(9), 5042-5051 (1998).
-
(1998)
Mol. Cell Biol.
, vol.18
, Issue.9
, pp. 5042-5051
-
-
Ma, O.1
Graus-Porta, D.2
Beerli, R.R.3
Rohrer, J.4
Gay, B.5
Hynes, N.E.6
-
37
-
-
0034992521
-
The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
-
Prenzel N, Fischer OM, Streit S, Hart S, Ullrich A: The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr. Relat. Cancer 8(1), 11-31 (2001).
-
(2001)
Endocr. Relat. Cancer
, vol.8
, Issue.1
, pp. 11-31
-
-
Prenzel, N.1
Fischer, O.M.2
Streit, S.3
Hart, S.4
Ullrich, A.5
-
38
-
-
0032915392
-
Epidermal growth factor receptors: Critical mediators of multiple receptor pathways
-
Hackel PO, Zwick E, Prenzel N, Ullrich A: Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr. Opin. Cell Biol. 11(2), 184-189 (1990).
-
(1990)
Curr. Opin. Cell Biol.
, vol.11
, Issue.2
, pp. 184-189
-
-
Hackel, P.O.1
Zwick, E.2
Prenzel, N.3
Ullrich, A.4
-
39
-
-
0032142749
-
ErbB3 (HER3) interaction with the p85 regulatory subunit of phosphoinositide 3-kinase
-
Hellyer NJ, Cheng K, Koland JG: ErbB3 (HER3) interaction with the p85 regulatory subunit of phosphoinositide 3-kinase. Biochem. J. 333(Pt3), 757-763 (1998).
-
(1998)
Biochem. J.
, vol.333
, Issue.PART 3
, pp. 757-763
-
-
Hellyer, N.J.1
Cheng, K.2
Koland, J.G.3
-
40
-
-
0028216712
-
Identification of c-erbB-3 binding sites for phosphatidylinositol 3-kinase and SHC using an EGF receptor/cerbB-3 chimera
-
Prigent SA, Gullick WJ: Identification of c-erbB-3 binding sites for phosphatidylinositol 3-kinase and SHC using an EGF receptor/cerbB-3 chimera. EMBO J. 13(12), 2831-2841 (1994).
-
(1994)
EMBO J.
, vol.13
, Issue.12
, pp. 2831-2841
-
-
Prigent, S.A.1
Gullick, W.J.2
-
41
-
-
0035834663
-
Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 coreceptor
-
Hellyer NJ, Kim MS, Koland JG: Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 coreceptor. J. Biol. Chem. 276(45), 42153-42161 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.45
, pp. 42153-42161
-
-
Hellyer, N.J.1
Kim, M.S.2
Koland, J.G.3
-
42
-
-
0032579532
-
Lipid-regulated kinases: Some common themes at last
-
Downward J: Lipid-regulated kinases: some common themes at last. Science 279(5351), 673-674 (1998).
-
(1998)
Science
, vol.279
, Issue.5351
, pp. 673-674
-
-
Downward, J.1
-
43
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR, Dudek H, Tao X et al.: Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91(2), 231-241 (1997).
-
(1997)
Cell
, vol.91
, Issue.2
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
-
44
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone MH, Roy N, Stennicke HR et al.: Regulation of cell death protease caspase-9 by phosphorylation. Science 282(5392), 1318-1321 (1998).
-
(1998)
Science
, vol.282
, Issue.5392
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
-
45
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ et al.: Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96(6), 857-868 (1999).
-
(1999)
Cell
, vol.96
, Issue.6
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
-
46
-
-
0033517189
-
NF-B activation by tumour necrosis factor requires the Akt serine-threonine kinase
-
Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB: NF-B activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 401(6748), 82-85 (1999).
-
(1999)
Nature
, vol.401
, Issue.6748
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
47
-
-
0033517190
-
NF-B is a target of AKT in antiapoptotic PDGF signalling
-
Romashkova JA, Makarov SS: NF-B is a target of AKT in antiapoptotic PDGF signalling. Nature 401(6748), 86-90 (1999).
-
(1999)
Nature
, vol.401
, Issue.6748
, pp. 86-90
-
-
Romashkova, J.A.1
Makarov, S.S.2
-
48
-
-
0030890933
-
Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
-
Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN: Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl Acad. Sci. USA 94(8), 3627-3632 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, Issue.8
, pp. 3627-3632
-
-
Ahmed, N.N.1
Grimes, H.L.2
Bellacosa, A.3
Chan, T.O.4
Tsichlis, P.N.5
-
49
-
-
0034643331
-
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
-
Medema RH, Kops GJ, Bos JL, Burgering BM: AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 404(6779), 782-787 (2000).
-
(2000)
Nature
, vol.404
, Issue.6779
, pp. 782-787
-
-
Medema, R.H.1
Kops, G.J.2
Bos, J.L.3
Burgering, B.M.4
-
50
-
-
0027076771
-
Expression of the c-erbB3 gene product in breast cancer
-
Lemoine NR, Barnes DM, Hollywood DP et al.: Expression of the c-erbB3 gene product in breast cancer. Br. J. Cancer 66(6), 1116-1121 (1992).
-
(1992)
Br. J. Cancer
, vol.66
, Issue.6
, pp. 1116-1121
-
-
Lemoine, N.R.1
Barnes, D.M.2
Hollywood, D.P.3
-
51
-
-
0029818168
-
Expression of the type 1 tyrosine kinase growth factor EGF receptors c-erbB-2 and c-erbB-3 in bladder cancer
-
Rajkumar T, Stamp GWH, Pandha HS, Waxman J, Gullick WJ: Expression of the type 1 tyrosine kinase growth factor EGF receptors c-erbB-2 and c-erbB-3 in bladder cancer. J. Pathol. 179(4), 381-385 (1996).
-
(1996)
J. Pathol.
, vol.179
, Issue.4
, pp. 381-385
-
-
Rajkumar, T.1
Gwh, S.2
Pandha, H.S.3
Waxman, J.4
Gullick, W.J.5
-
52
-
-
17644387160
-
Coexpression of the type 1 growth factor receptor family members HER-1, HER-2, and HER-3 has a synergistic negative prognostic effect on breast carcinoma survival
-
Wiseman SM, Makretsov N, Nielsen TO et al.: Coexpression of the type 1 growth factor receptor family members HER-1, HER-2, and HER-3 has a synergistic negative prognostic effect on breast carcinoma survival. Cancer 103(9), 1770-1777 (2005).
-
(2005)
Cancer
, vol.103
, Issue.9
, pp. 1770-1777
-
-
Wiseman, S.M.1
Makretsov, N.2
Nielsen, T.O.3
-
53
-
-
0030942007
-
Clinical and prognostic significance of the expression of the c-erbB-2 and c-erbB-3 oncoproteins in primary and metastatic malignant melanomas and breast carcinomas
-
Bodey B, Bodey B Jr, Groger AM et al.: Clinical and prognostic significance of the expression of the c-erbB-2 and c-erbB-3 oncoproteins in primary and metastatic malignant melanomas and breast carcinomas. Anticancer Res. 17(2B), 1319-1330 (1997).
-
(1997)
Anticancer Res.
, vol.17
, Issue.2
, pp. 1319-1330
-
-
Bodey, B.1
Bodey Jr., B.2
Groger, A.M.3
-
54
-
-
0029053716
-
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation
-
Alimandi M, Romano A, Curia MC et al.: Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation. Oncogene 10(9), 1813-1821 (1995).
-
(1995)
Oncogene
, vol.10
, Issue.9
, pp. 1813-1821
-
-
Alimandi, M.1
Romano, A.2
Curia, M.C.3
-
55
-
-
0028148050
-
Intracellular expression of single chain antibodies reverts ErbB-2 transformation
-
Beerli RR, Wels W, Hynes NE: Intracellular expression of single chain antibodies reverts ErbB-2 transformation. J. Biol. Chem. 269(39), 23931-23936 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, Issue.39
, pp. 23931-23936
-
-
Beerli, R.R.1
Wels, W.2
Hynes, N.E.3
-
56
-
-
0034704870
-
Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells
-
Neve RM, Sutterlüty H, Pullen N et al.: Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells. Oncogene 19(13), 1647-1656 (2000).
-
(2000)
Oncogene
, vol.19
, Issue.13
, pp. 1647-1656
-
-
Neve, R.M.1
Sutterlüty, H.2
Pullen, N.3
-
57
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr CJ, Roberts JM: CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13(12), 1501-1512 (1999).
-
(1999)
Genes Dev.
, vol.13
, Issue.12
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
58
-
-
0033996361
-
ErbB2 potentiates breast tumor proliferation through modulation of p27Kip1/Cdk2 complex formation: Receptor overexpression does not determine growth dependency
-
Lane HA, Beuvink I, Motoyama AB, Daly JM, Neve RM, Hynes NE: ErbB2 potentiates breast tumor proliferation through modulation of p27Kip1/Cdk2 complex formation: receptor overexpression does not determine growth dependency. Mol. Cell. Biol. 20(9), 3210-3223 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, Issue.9
, pp. 3210-3223
-
-
Lane, H.A.1
Beuvink, I.2
Motoyama, A.B.3
Daly, J.M.4
Neve, R.M.5
Hynes, N.E.6
-
59
-
-
0023187324
-
Overexpression of the c-erbB-2 oncoprotein in human breast carcinomas: Immunohistological assessment correlates with gene amplification
-
Venter DJ, Tuzi NL, Kumar S, Gullick WJ: Overexpression of the c-erbB-2 oncoprotein in human breast carcinomas: immunohistological assessment correlates with gene amplification. Lancet 2(8550), 69-72 (1987).
-
(1987)
Lancet
, vol.2
, Issue.8550
, pp. 69-72
-
-
Venter, D.J.1
Tuzi, N.L.2
Kumar, S.3
Gullick, W.J.4
-
60
-
-
0029884715
-
Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization
-
Pauletti G, Godolphin W, Press MF, Slamon DJ: Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization. Oncogene 13(1), 63-72 (1996).
-
(1996)
Oncogene
, vol.13
, Issue.1
, pp. 63-72
-
-
Pauletti, G.1
Godolphin, W.2
Press, M.F.3
Slamon, D.J.4
-
61
-
-
0026793986
-
Overexpression of HER-2/neu and its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer
-
Allred DC, Clarke GM, Molina R et al.: Overexpression of HER-2/neu and its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer. Hum. Pathol. 23(9), 974-979 (1992).
-
(1992)
Hum. Pathol.
, vol.23
, Issue.9
, pp. 974-979
-
-
Allred, D.C.1
Clarke, G.M.2
Molina, R.3
-
62
-
-
0029053716
-
Cooperative signaling of erbB3 and erbB2 in neoplastic transformation and human mammary carcinomas
-
Alimandi M, Romano A, Curia MC et al.: Cooperative signaling of erbB3 and erbB2 in neoplastic transformation and human mammary carcinomas. Oncogene 10(9), 1813-1821 (1985).
-
(1985)
Oncogene
, vol.10
, Issue.9
, pp. 1813-1821
-
-
Alimandi, M.1
Romano, A.2
Curia, M.C.3
-
63
-
-
0034234854
-
Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2
-
Klapper LN, Waterman H, Sela M, Yarden Y: Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2. Cancer Res. 60(13), 3384-3388 (2000).
-
(2000)
Cancer Res.
, vol.60
, Issue.13
, pp. 3384-3388
-
-
Klapper, L.N.1
Waterman, H.2
Sela, M.3
Yarden, Y.4
-
64
-
-
0034634678
-
C-Cbl is a suppressor of the neu oncogene
-
Levkowitz G, Klapper LN, Harari D, Lavi S, Sela M, Yarden Y: c-Cbl is a suppressor of the neu oncogene. J. Biol. Chem. 275(45), 35532-35539 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.45
, pp. 35532-35539
-
-
Levkowitz, G.1
Klapper, L.N.2
Harari, D.3
Lavi, S.4
Sela, M.5
Yarden, Y.6
-
65
-
-
0028233833
-
Depletion of the erbB-2 gene product p185 by benzoquinoid ansamycins
-
Miller P, DiOrio C, Moyer M et al.: Depletion of the erbB-2 gene product p185 by benzoquinoid ansamycins. Cancer Res. 54(10), 2724-2730 (1994).
-
(1994)
Cancer Res.
, vol.54
, Issue.10
, pp. 2724-2730
-
-
Miller, P.1
Diorio, C.2
Moyer, M.3
-
66
-
-
0029812759
-
Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin
-
Mimnaugh EG, Chavany C, Neckers L: Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin. J. Biol. Chem. 271(37), 22796-22801 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.37
, pp. 22796-22801
-
-
Mimnaugh, E.G.1
Chavany, C.2
Neckers, L.3
-
67
-
-
0033502429
-
Geldanamycin as a potential anti-cancer agent: Its molecular target and biochemical activity
-
Neckers L, Schulte TW, Mimnaugh E: Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity. Invest. New Drugs 17(4), 361-373 (1999).
-
(1999)
Invest. New Drugs
, vol.17
, Issue.4
, pp. 361-373
-
-
Neckers, L.1
Schulte, T.W.2
Mimnaugh, E.3
-
68
-
-
0022965150
-
International comparisons of mortality rates for cancer of the breast, ovary, prostate, and colon, and per capita food consumption
-
Rose DP, Boyar AP, Wynder EL: International comparisons of mortality rates for cancer of the breast, ovary, prostate, and colon, and per capita food consumption. Cancer 58(11), 2363-2371 (1986).
-
(1986)
Cancer
, vol.58
, Issue.11
, pp. 2363-2371
-
-
Rose, D.P.1
Boyar, A.P.2
Wynder, E.L.3
-
69
-
-
0026564258
-
Genotoxicities of nitropyrenes and their modulation by apigenin, tannic acid, ellagic acid and indole-3-carbinol in the Salmonella and CHO systems
-
Kuo ML, Lee KC, Lin JK: Genotoxicities of nitropyrenes and their modulation by apigenin, tannic acid, ellagic acid and indole-3-carbinol in the Salmonella and CHO systems. Mutat. Res. 270(2), 87-95 (1992).
-
(1992)
Mutat. Res.
, vol.270
, Issue.2
, pp. 87-95
-
-
Kuo, M.L.1
Lee, K.C.2
Lin, J.K.3
-
70
-
-
0027996480
-
Apigenin and tangeretin enhance gap junctional intercellular communication in rat liver epithelial cells
-
Chaumontet C, Bex V, Gaillard-Sanchez I, Seillan-Heberden C, Suschetet M, Martel P: Apigenin and tangeretin enhance gap junctional intercellular communication in rat liver epithelial cells. Carcinogenesis 15(10), 2325-2330 (1994).
-
(1994)
Carcinogenesis
, vol.15
, Issue.10
, pp. 2325-2330
-
-
Chaumontet, C.1
Bex, V.2
Gaillard-Sanchez, I.3
Seillan-Heberden, C.4
Suschetet, M.5
Martel, P.6
-
71
-
-
0029080674
-
Reversion of v-H-rastransformed NIH 3T3 cells by apigenin through inhibiting mitogen activated protein kinase and its downstream oncogenes
-
Kuo ML, Yang NC: Reversion of v-H-rastransformed NIH 3T3 cells by apigenin through inhibiting mitogen activated protein kinase and its downstream oncogenes. Biochem. Biophys. Res. Commun. 212(3), 767-775 (1995).
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.212
, Issue.3
, pp. 767-775
-
-
Kuo, M.L.1
Yang, N.C.2
-
72
-
-
11144307476
-
Degradation of HER2/neu by apigenin induces apoptosis through cytochrome c release and caspase-3 activation in HER2/neu-overexpressing breast cancer cells
-
Way TD, Kao MC, Lin JK: Degradation of HER2/neu by apigenin induces apoptosis through cytochrome c release and caspase-3 activation in HER2/neu-overexpressing breast cancer cells. FEBS Lett. 579(1), 145-152 (2005).
-
(2005)
FEBS Lett.
, vol.579
, Issue.1
, pp. 145-152
-
-
Way, T.D.1
Kao, M.C.2
Lin, J.K.3
|