메뉴 건너뛰기




Volumn 67, Issue 16, 2007, Pages 7782-7788

Androgen receptor- and E2F-1-targeted thymoquinone therapy for hormone-refractory prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PROTEIN BAX; THYMOQUINONE; TRANSCRIPTION FACTOR E2F1;

EID: 34548015409     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-1483     Document Type: Article
Times cited : (201)

References (40)
  • 1
  • 2
    • 0021721949 scopus 로고
    • Metastatic patterns of prostatic cancer. Correlation between sites and number of organs involved
    • Saitoh H, Hida M, Shimbo T, Nakamura K, Yamagata J, Satoh T. Metastatic patterns of prostatic cancer. Correlation between sites and number of organs involved. Cancer 1984;54:3078-84.
    • (1984) Cancer , vol.54 , pp. 3078-3084
    • Saitoh, H.1    Hida, M.2    Shimbo, T.3    Nakamura, K.4    Yamagata, J.5    Satoh, T.6
  • 3
    • 0034085989 scopus 로고    scopus 로고
    • Metastatic patterns of prostate cancer: An autopsy study of 1,589 patients
    • Bubendorf L, Schopfer A, Wagner U, et al. Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum Pathol 2000;31:578-83.
    • (2000) Hum Pathol , vol.31 , pp. 578-583
    • Bubendorf, L.1    Schopfer, A.2    Wagner, U.3
  • 5
    • 0031077802 scopus 로고    scopus 로고
    • Basic science aspects of prostate cancer
    • Dorkin TJ, Neal DE. Basic science aspects of prostate cancer. Semin Cancer Biol 1997;8:21-7.
    • (1997) Semin Cancer Biol , vol.8 , pp. 21-27
    • Dorkin, T.J.1    Neal, D.E.2
  • 6
    • 0037599536 scopus 로고    scopus 로고
    • Androgen receptor involvement in the progression of prostate cancer
    • Suzuki H, Ueda T, Ichikawa T, Ito H. Androgen receptor involvement in the progression of prostate cancer. Endocr Relat Cancer 2003;10:209-16.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 209-216
    • Suzuki, H.1    Ueda, T.2    Ichikawa, T.3    Ito, H.4
  • 7
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001;1:34-45.
    • (2001) Nat Rev Cancer , vol.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 8
    • 33746538284 scopus 로고    scopus 로고
    • Regulatory processes affecting androgen receptor expression, stability, and function: Potential targets to treat hormone-refractory prostate cancer
    • Reddy GP, Barrack ER, Dou QP, et al. Regulatory processes affecting androgen receptor expression, stability, and function: potential targets to treat hormone-refractory prostate cancer. J Cell Biochem 2006;98:1408-23.
    • (2006) J Cell Biochem , vol.98 , pp. 1408-1423
    • Reddy, G.P.1    Barrack, E.R.2    Dou, Q.P.3
  • 10
    • 24744451451 scopus 로고    scopus 로고
    • Cancer chemotherapy by deoxynucleotide depletion and E2F-1 elevation
    • Wang A, Li CJ, Reddy GP, Pardee AB. Cancer chemotherapy by deoxynucleotide depletion and E2F-1 elevation. Cancer Res 2005;65:7809-14.
    • (2005) Cancer Res , vol.65 , pp. 7809-7814
    • Wang, A.1    Li, C.J.2    Reddy, G.P.3    Pardee, A.B.4
  • 12
    • 33750902614 scopus 로고    scopus 로고
    • Putting the oncogenic and tumor suppressive activities of E2F into context
    • Johnson DG, Degregori J. Putting the oncogenic and tumor suppressive activities of E2F into context. Curr Mol Med 2006;6:731-8.
    • (2006) Curr Mol Med , vol.6 , pp. 731-738
    • Johnson, D.G.1    Degregori, J.2
  • 13
    • 33846244227 scopus 로고    scopus 로고
    • Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer
    • Davis JN, Wojno KJ, Daignault S, et al. Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer. Cancer Res 2006;66:11897-906.
    • (2006) Cancer Res , vol.66 , pp. 11897-11906
    • Davis, J.N.1    Wojno, K.J.2    Daignault, S.3
  • 14
    • 33748047128 scopus 로고    scopus 로고
    • Rb and cell cycle progression
    • Giacinti C, Giordano A. Rb and cell cycle progression. Oncogene 2006;25:5220-7.
    • (2006) Oncogene , vol.25 , pp. 5220-5227
    • Giacinti, C.1    Giordano, A.2
  • 15
    • 0034327299 scopus 로고    scopus 로고
    • Sex hormone-induced carcinogenesis in Rb-deficient prostate tissue
    • Wang Y, Hayward SW, Donjacour AA, et al. Sex hormone-induced carcinogenesis in Rb-deficient prostate tissue. Cancer Res 2000;60:6008-17.
    • (2000) Cancer Res , vol.60 , pp. 6008-6017
    • Wang, Y.1    Hayward, S.W.2    Donjacour, A.A.3
  • 16
    • 29344474660 scopus 로고    scopus 로고
    • E2F1 expression in LNCaP prostate cancer cells deregulates androgen dependent growth, suppresses differentiation, and enhances apoptosis
    • Libertini SJ, Tepper CG, Guadalupe M, Lu Y, Asmuth DM, Mudryj M. E2F1 expression in LNCaP prostate cancer cells deregulates androgen dependent growth, suppresses differentiation, and enhances apoptosis. Prostate 2006;66:70-81.
    • (2006) Prostate , vol.66 , pp. 70-81
    • Libertini, S.J.1    Tepper, C.G.2    Guadalupe, M.3    Lu, Y.4    Asmuth, D.M.5    Mudryj, M.6
  • 17
    • 11844252588 scopus 로고    scopus 로고
    • Risk of fracture after androgen deprivation for prostate cancer
    • Shahinian VB, Kuo YF, Freeman JL, Goodwin JS. Risk of fracture after androgen deprivation for prostate cancer. N Engl J Med 2005;352:154-64.
    • (2005) N Engl J Med , vol.352 , pp. 154-164
    • Shahinian, V.B.1    Kuo, Y.F.2    Freeman, J.L.3    Goodwin, J.S.4
  • 18
    • 33744490370 scopus 로고    scopus 로고
    • Biological effects of curcumin and its role in cancer chemoprevention and therapy
    • Singh S, Khar A. Biological effects of curcumin and its role in cancer chemoprevention and therapy. Anticancer Agents Med Chem 2006;6:259-70.
    • (2006) Anticancer Agents Med Chem , vol.6 , pp. 259-270
    • Singh, S.1    Khar, A.2
  • 19
    • 33744915312 scopus 로고    scopus 로고
    • Critical role of pro-apoptotic Bcl-2 family members in andrographolide-induced apoptosis in human cancer cells
    • Zhou J, Zhang S, Choon-Nam O, Shen HM. Critical role of pro-apoptotic Bcl-2 family members in andrographolide-induced apoptosis in human cancer cells. Biochem Pharmacol 2006;72:132-44.
    • (2006) Biochem Pharmacol , vol.72 , pp. 132-144
    • Zhou, J.1    Zhang, S.2    Choon-Nam, O.3    Shen, H.M.4
  • 20
    • 33645214868 scopus 로고    scopus 로고
    • Complementary and alternative therapeutic approaches in patients with early breast cancer: A systematic review
    • Gerber B, Scholz C, Reimer T, Briese V, Janni W. Complementary and alternative therapeutic approaches in patients with early breast cancer: a systematic review. Breast Cancer Res Treat 2006;95:199-209.
    • (2006) Breast Cancer Res Treat , vol.95 , pp. 199-209
    • Gerber, B.1    Scholz, C.2    Reimer, T.3    Briese, V.4    Janni, W.5
  • 22
    • 0038559976 scopus 로고    scopus 로고
    • Pharmacological and toxicological properties of Nigella sativa
    • Ali BH, Blunden G. Pharmacological and toxicological properties of Nigella sativa. Phytother Res 2003;17:299-305.
    • (2003) Phytother Res , vol.17 , pp. 299-305
    • Ali, B.H.1    Blunden, G.2
  • 23
    • 0031878048 scopus 로고    scopus 로고
    • The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L
    • Worthen DR, Ghosheh OA, Crooks PA. The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L. Anticancer Res 1998;18:1527-32.
    • (1998) Anticancer Res , vol.18 , pp. 1527-1532
    • Worthen, D.R.1    Ghosheh, O.A.2    Crooks, P.A.3
  • 25
    • 0033120349 scopus 로고    scopus 로고
    • High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.)
    • Ghosheh OA, Houdi AA, Crooks PA. High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.). J Pharm Biomed Anal 1999;19:757-62.
    • (1999) J Pharm Biomed Anal , vol.19 , pp. 757-762
    • Ghosheh, O.A.1    Houdi, A.A.2    Crooks, P.A.3
  • 26
    • 13244285843 scopus 로고    scopus 로고
    • Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism
    • Gali-Muhtasib H, Diab-Assaf M, Boltze C, et al. Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism. Int J Oncol 2004;25:857-66.
    • (2004) Int J Oncol , vol.25 , pp. 857-866
    • Gali-Muhtasib, H.1    Diab-Assaf, M.2    Boltze, C.3
  • 27
    • 1942485326 scopus 로고    scopus 로고
    • Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes
    • Gali-Muhtasib HU, Abou Kheir WG, Kheir LA, Darwiche N, Crooks PA. Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes. Anticancer Drugs 2004;15:389-99.
    • (2004) Anticancer Drugs , vol.15 , pp. 389-399
    • Gali-Muhtasib, H.U.1    Abou Kheir, W.G.2    Kheir, L.A.3    Darwiche, N.4    Crooks, P.A.5
  • 28
    • 33745219871 scopus 로고    scopus 로고
    • The physiological effect of conventional treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid on the LNCaP cell line
    • Richards LR, Jones P, Hughes J, Benghuzzi H, Tucci M. The physiological effect of conventional treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid on the LNCaP cell line. Biomed Sci Instrum 2006;42:357-62.
    • (2006) Biomed Sci Instrum , vol.42 , pp. 357-362
    • Richards, L.R.1    Jones, P.2    Hughes, J.3    Benghuzzi, H.4    Tucci, M.5
  • 29
    • 0037731923 scopus 로고    scopus 로고
    • Synchronized prostate cancer cells for studying androgen regulated events in cell cycle progression from G1 into S phase
    • Cifuentes E, Croxen R, Menon M, Barrack ER, Reddy GP. Synchronized prostate cancer cells for studying androgen regulated events in cell cycle progression from G1 into S phase. J Cell Physiol 2003;195:337-45.
    • (2003) J Cell Physiol , vol.195 , pp. 337-345
    • Cifuentes, E.1    Croxen, R.2    Menon, M.3    Barrack, E.R.4    Reddy, G.P.5
  • 30
    • 0029202881 scopus 로고
    • Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1
    • Hayward SW, Dahiya R, Cunha GR, Bartek J, Deshpande N, Narayan P. Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1. In Vitro Cell Dev Biol Anim 1995;31:14-24.
    • (1995) In Vitro Cell Dev Biol Anim , vol.31 , pp. 14-24
    • Hayward, S.W.1    Dahiya, R.2    Cunha, G.R.3    Bartek, J.4    Deshpande, N.5    Narayan, P.6
  • 31
    • 34047233908 scopus 로고    scopus 로고
    • Stabilizing androgen receptor in mitosis inhibits prostate cancer proliferation
    • Vander Griend DJ, Litvinov IV, Isaacs JT. Stabilizing androgen receptor in mitosis inhibits prostate cancer proliferation. Cell Cycle 2007;6:647-51.
    • (2007) Cell Cycle , vol.6 , pp. 647-651
    • Vander Griend, D.J.1    Litvinov, I.V.2    Isaacs, J.T.3
  • 32
    • 33846213525 scopus 로고    scopus 로고
    • Calmodulin-androgen receptor (AR) interaction: Calcium-dependent, calpain-mediated breakdown of AR in LNCaP prostate cancer cells
    • Pelley RP, Chinnakannu K, Murthy S, et al. Calmodulin-androgen receptor (AR) interaction: calcium-dependent, calpain-mediated breakdown of AR in LNCaP prostate cancer cells. Cancer Res 2006;66:11754-62.
    • (2006) Cancer Res , vol.66 , pp. 11754-11762
    • Pelley, R.P.1    Chinnakannu, K.2    Murthy, S.3
  • 33
    • 0032497588 scopus 로고    scopus 로고
    • Regulation of cell growth-dependent expression of mammalian CDC6 gene by the cell cycle transcription factor E2F
    • Ohtani K, Tsujimoto A, Ikeda M, Nakamura M. Regulation of cell growth-dependent expression of mammalian CDC6 gene by the cell cycle transcription factor E2F. Oncogene 1998;17:1777-85.
    • (1998) Oncogene , vol.17 , pp. 1777-1785
    • Ohtani, K.1    Tsujimoto, A.2    Ikeda, M.3    Nakamura, M.4
  • 34
    • 0033863612 scopus 로고    scopus 로고
    • Hormone-resistant prostate cancer with symptomatic pelvic tumours: Patient survival and prognostic factors
    • Hernes EH, Linja M, Fossa SD, et al. Hormone-resistant prostate cancer with symptomatic pelvic tumours: patient survival and prognostic factors. BJU Int 2000;86:240-7.
    • (2000) BJU Int , vol.86 , pp. 240-247
    • Hernes, E.H.1    Linja, M.2    Fossa, S.D.3
  • 35
    • 0025774015 scopus 로고
    • Inhibitory effects of Nigella sativa and saffron (Crocus sativus) on chemical carcinogenesis in mice
    • Salomi MJ, Nair SC, Panikkar KR. Inhibitory effects of Nigella sativa and saffron (Crocus sativus) on chemical carcinogenesis in mice. Nutr Cancer 1991;16:67-72.
    • (1991) Nutr Cancer , vol.16 , pp. 67-72
    • Salomi, M.J.1    Nair, S.C.2    Panikkar, K.R.3
  • 36
    • 0012980550 scopus 로고    scopus 로고
    • In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone
    • Shoieb AM, Elgayyar M, Dudrick PS, Bell JL, Tithof PK. In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone. Int J Oncol 2003;22:107-13.
    • (2003) Int J Oncol , vol.22 , pp. 107-113
    • Shoieb, A.M.1    Elgayyar, M.2    Dudrick, P.S.3    Bell, J.L.4    Tithof, P.K.5
  • 37
    • 26444457920 scopus 로고    scopus 로고
    • Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells
    • El-Mahdy MA, Zhu Q, Wang QE, Wani G, Wani AA. Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells. Int J Cancer 2005;117:409-17.
    • (2005) Int J Cancer , vol.117 , pp. 409-417
    • El-Mahdy, M.A.1    Zhu, Q.2    Wang, Q.E.3    Wani, G.4    Wani, A.A.5
  • 39
    • 0037022558 scopus 로고    scopus 로고
    • Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: A DNA microarray analysis
    • Song YJ, Stinski MF. Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: a DNA microarray analysis. Proc Natl Acad Sci U S A 2002;99:2836-41.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 2836-2841
    • Song, Y.J.1    Stinski, M.F.2
  • 40
    • 0028267869 scopus 로고    scopus 로고
    • La Thangue NB. DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control. Trends Biochem Sci 1994;19:108-14.
    • La Thangue NB. DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control. Trends Biochem Sci 1994;19:108-14.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.