Green tea polyphenols modulate secretion of urokinase plasminogen activator (uPA) and inhibit invasive behavior of breast cancer cells

Nutrition and Cancer

Volumn 52, Issue 1, 2005, Pages 66-73

  Slivova, Veronika ^a   Zaloga, Gary ^b   DeMichele, Stephen J ^c   Mukerji, Pradip ^c   Huang, Yung Sheng ^c   Siddiqui, Rafat ^a   Harvey, Kevin ^a   Valachovicova, Tatiana ^a   Sliva, Daniel ^a  

^a METHODIST RESEARCH INSTITUTE   (United States)

^b INDIANA UNIVERSITY   (United States)

^c ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; GALLIC ACID; GALLOCATECHIN; GALLOCATECHIN GALLATE; GREEN TEA EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN RECEPTOR; POLYPHENOL DERIVATIVE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; UROKINASE; UROKINASE RECEPTOR; VITRONECTIN;

ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; ENZYME RELEASE; EVALUATION; HUMAN; HUMAN CELL; METASTASIS; TEA;

BREAST NEOPLASMS; CELL ADHESION; CELL DIVISION; CELL MOVEMENT; FEMALE; FLAVONOIDS; HUMANS; NEOPLASM INVASIVENESS; PHENOLS; RECEPTORS, CELL SURFACE; TEA; TUMOR CELLS, CULTURED; URINARY PLASMINOGEN ACTIVATOR;

ANIMALIA;

EID: 24144451076     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/s15327914nc5201_9     Document Type: Article

References (42)

1. Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, et al.: Cancer statistics, 2004. CA Cancer J Clin 54, 8-29, 2004.
2. Price JT, Bonovich MT, and Kohn EC: The biochemistry of cancer dissemination. Crit Rev Biochem Mol Biol 32, 175-253, 1997.
3. Blasi F and Carmeliet P: uPAR: a versatile signaling orchestrator. Nat Rev Mol Cell Biol 3, 932-943, 2002.
4. Katiyar SK and Mukhtar H: Tea in chemoprevention of cancer: epidemiologic and experimental studies (review). Int J Oncol 8, 221-238, 1996.
5. Yang CS, Maliakal P, and Meng X: Inhibition of carcinogeneis by tea. Annu Rev Pharmacol Toxicol 42, 25-54, 2002.
6. Liao J, Yang GY, Park ES, Meng X, Sun Y, et al.: Inhibition of lung carcinogenesis and effects on angiogenesis and apoptosis in A/J mice by oral administration of green tea. Nutr Cancer 48, 44-53, 2004.
7. Yang GY, Liu Z, Seril DN, Liao J, Ding W, et al.: Black tea constituents, theaflavins, inhibit 4-(methylnitrosarnino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice. Carcinogenesis 18, 2361-2365, 1997.
8. Buschman JL: Green tea and cancer in humans: a review of the literature. Nutr Cancer 31, 151-159, 1998.
9. Wu AH, Yu MC, Tseng CC, Hankin J, and Pike MC: Green tea and risk of breast cancer in Asian Americans. Int J Cancer 106, 574-579, 2003.
10. Suzuki Y, Tsubono Y, Nakaya N, Suzuki Y, Koizumi Y, et al.: Green tea and the risk of breast cancer: pooled analysis of two prospective studies in Japan. Br J Cancer 90, 1361-1363, 2004.
11. Pianetti S, Guo S, Kavanagh KT, and Sonenshein GE: Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells. Cancer Res 62, 652-655, 2002.
12. Masuda M, Suzui M, Lim JT, Deguchi A, Soh JW, et al.: Epigallocatechin-3-gallate decreases VEGF production in head and neck and breast carcinoma cells by inhibiting EGFR-related pathways of signal transduction. J Exp Ther Oncol 2, 350-359, 2002.
13. Liao S, Umekita Y, Guo J, Kokontis JM, and Hiipakka RA: Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate. Cancer Lett 96, 239-243, 1995.
14. Sartippour MR, Heber D, Ma J, Lu Q, Go VL, et al.: Green tea and its catechins inhibit breast cancer xenografts. Nutr Cancer 40, 149-156, 2001.
15. Sliva D, English D, Lyons D, and Lloyd Jr FP: Protein kinase C induces motility of breast cancers by upregulating secretion of urokinase-type plasminogen activator (uPA) through the activation of AP-1 and NF-KB. Biochem Biophys Res Commun 290, 552-557, 2002.
16. Sliva D, Rizzo MT, and English D: Phosphatidylinositol 3-kinase and NF-κB regulate motility of invasive MDA-MB-231 human breast cancer cells by the secretion of urokinase-type plasminogen activator (uPA). J Biol Chem 277, 3150-3157, 2002.
17. Sliva D, Labarrere C, Slivova V, Sedlak M, Lloyd Jr FP, et al.: Ganoderma lucidum suppresses motility of highly invasive breast and prostate cancer cells. Biochem Biophys Res Commun 298, 603-612, 2002.
18. Jiang J, Slivova V, Valachovicova T, Harvey K, and Sliva D: Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3. Int J Oncol 24, 1093-1099, 2004.
19. Sliva D, Harvey K, Mason R, Lloyd Jr F, and English D: Effect of phosphatidic acid on human breast cancer cells exposed to doxorubicin. Cancer Invest 19, 781-788, 2001.
20. Lloyd Jr FP, Slivova V, Valachovicova T, and Sliva D: Aspirin inhibits highly invasive prostate cancer cells. Int J Oncol 23, 1277-1283, 2003.
21. Slivova V, Valachovicova T, Jiang J, and Sliva D: Ganoderma lucidum inhibits invasiveness of breast cancer cell. J Cancer Integr Med 2, 25-30, 2004.
22. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, et al. (eds.): Current Protocol in Molecular Biology. New York: Wiley, 1990, pp 9.7.1.2-9.7.1.8.
23. Gupta S, Hastak K, Ahmad N, Lewin JS, and Mukhtar H: Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols. Proc Natl Acad Sci USA 98, 10350-10355, 2001.
24. Freedman VH and Shin SI: Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell 3, 355-359, 1974.
25. Dong Z, Ma W, Huang Z, and Yang CS: Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins. Cancer Res 57, 4414-4419, 1997.
26. Sartippour MR, Shao ZM, Heber D, Beatty P, Zhang L, et al.: Green tea inhibits vascular endothelial growth factor (VEGF) induction in human breast cancer cells. J Nutr 132, 2307-2311, 2002.
27. Afaq F, Ahmad N, and Mukhtar H: Suppression of UVB-induced phosphorylation of mitogen-activated protein kinases and nuclear factor kappa B by green tea polyphenol in SKH-1 hairless mice. Oncogene 22, 9254-9264, 2003.
28. Nerlov C, Rorth P, Blasi F, and Johnsen M: Essential AP-1 and PEA3 binding elements in the human urokinase enhancer display cell type-specific activity. Oncogene 6, 1583-1593, 1991.
29. Lengyel E, Gum R, Stepp E, Juarez J, Wang H, et al.: Regulation of urokinase-type plasminogen activator expression by an ERK1-dependent signaling pathway in a squamous cell carcinoma cell line. J Cell Biochem 61, 430-438, 1996.
30. Kim MH, Jung MA, Hwang YS, Jeong M, Kim SM, et al.: Regulation of urokinase plasminogen activator by epigallocatechin-3-gallate in human fibrosarcoma cells. Eur J Pharmacol 487, 1-6, 2004.
31. Yu AE, Hewitt RE, Connor EW, and Stetler-Stevenson WG: Matrix metalloproteinases. Novel targets for directed cancer therapy. Drugs Aging 11, 229-244, 1997.
32. Chapman HA, Riese RJ, and Shi GP: Emerging roles for cysteine proteases in human biology. Annu Rev Physiol 59, 63-88, 1997.
33. Andreasen PA, Kjøller L, Christensen L, and Duffy MJ: The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer 72, 1-22, 1997.
34. Blasi F: uPA-uPA-PAI-I: a key intersection in proteolysis, adhesion and chemotaxis. Immunol Today 18, 415-417, 1997.
35. Wong NC, Mueller BM, Barbas CF, Ruminski P, Quaranta V, et al.: Alphav integrins mediate adhesion and migration of breast carcinoma cell lines. Clin Exp Metastasis 16, 50-61, 1998.
36. Lambert JD and Yang, CS: Mechanisms of cancer prevention by tea constituents. J Nutr 133, 3262S-3267S, 2003.
37. Kavanagh KT, Hafer LJ, Kim DW, Mann KK, Sherr DH, et al.: Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture. J Cell Biochem 82, 387-398, 2001.
38. Lambert JD, Hong J, Yang GY, and Yang CS: Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations. Am J Clin Nutr 81, 284S-291S, 2005.
39. Sallem M, Adhami VM, Siddiqui IA, and Mukhtar H: Tea beverage in chemoprevention of prostate cancer: a mini-review. Nutr Cancer 47, 13-23, 2003.
40. Lee MJ, Maliakal P, Chen L, Meng X, Bondoc FY, et al.: Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability. Cancer Epidemiol Biomarkers Prev 11, 1025-1032, 2002.
41. Suganuma M, Okabe S, Oniyama M, Tada Y, Ito H, et al.: Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue. Carcinogenesis 19, 1771-1776, 1998.
42. Kohri T, Matsumoto N, Yamakawa M, Suzuki M, Nanjo F, et al.: Metabolic fate of (-)-[4-(3)H]epigallocatechin gallate in rats after oral administration. J Agric Food Chem 49, 4102-4112, 2001.