Induction of Apoptosis in Human Myeloid Leukemic Cells by 1′-Acetoxychavicol Acetate through a Mitochondrial- and Fas-Mediated Dual Mechanism

Clinical Cancer Research

Volumn 10, Issue 6, 2004, Pages 2120-2130

  Ito, Keisuke ^a   Nakazato, Tomonori ^a   Murakami, Akira ^b   Yamato, Kenji ^c   Miyakawa, Yoshitaka ^a   Yamada, Taketo ^a   Hozumi, Nobumichi ^d   Ohigashi, Hajime ^b   Ikeda, Yasuo ^a   Kizaki, Masahiro ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1' ACETOXYCHAVICOL ACETATE; ACETIC ACID DERIVATIVE; ACETYLCYSTEINE; ANTIOXIDANT; CASPASE 8; CASPASE 9; FAS ANTIBODY; FAS ANTIGEN; NATURAL PRODUCT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ZB4 ANTIBODY;

ADULT; AGED; ANIMAL MODEL; ANIMAL TISSUE; ANTILEUKEMIC EFFECT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER SURVIVAL; CELL STRAIN NB4; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SENSITIVITY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LANGUAS GALANGA; LEUKEMIA CELL; LOW DRUG DOSE; MALE; MEDICINAL PLANT; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; MOUSE STRAIN; MYELOID LEUKEMIA; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SCID MOUSE;

ADULT; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL DIVISION; CELL LINE, TUMOR; FEMALE; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MALE; MIDDLE AGED; MITOCHONDRIA; PHYTOTHERAPY; TERPENES; TUMOR CELLS, CULTURED;

EID: 12144286272     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-1142-03     Document Type: Article

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