The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP

Neurochemistry International

Volumn 55, Issue 6, 2009, Pages 423-430

  Siegelin, M D ^a,c   Gaiser, Timo ^a   Siegelin, Y ^b  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

c FLIP; Embelin; Glioma; TRAIL Apo2L

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; EMBELIN; FLICE INHIBITORY PROTEIN; ISOPROTEIN; MESSENGER RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BENZOQUINONES; BRAIN NEOPLASMS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL LINE; CELL LINE, TUMOR; DOWN-REGULATION; DRUG SYNERGISM; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; PROTEIN ISOFORMS; RNA, MESSENGER; TNF-RELATED APOPTOSIS-INDUCING LIGAND; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 67650080174     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2009.04.011     Document Type: Article

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