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Volumn 71, Issue C, 2010, Pages 125-176

Epigenetic Alterations as Cancer Diagnostic, Prognostic, and Predictive Biomarkers

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; TUMOR MARKER;

EID: 77957353074     PISSN: 00652660     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-380864-6.00005-5     Document Type: Book
Times cited : (73)

References (301)
  • 1
    • 33644878393 scopus 로고    scopus 로고
    • Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients
    • Aggerholm A., Holm M.S., Guldberg P., Olesen L.H., Hokland P. Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients. Eur. J. Haematol. 2006, 76:23-32.
    • (2006) Eur. J. Haematol. , vol.76 , pp. 23-32
    • Aggerholm, A.1    Holm, M.S.2    Guldberg, P.3    Olesen, L.H.4    Hokland, P.5
  • 3
    • 53049090443 scopus 로고    scopus 로고
    • Prognostic significance of aberrant promoter hypermethylation of CpG islands in patients with diffuse large B-cell lymphomas
    • Amara K., Trimeche M., Ziadi S., Laatiri A., Hachana M., Korbi S. Prognostic significance of aberrant promoter hypermethylation of CpG islands in patients with diffuse large B-cell lymphomas. Ann. Oncol. 2008, 19:1774-1786.
    • (2008) Ann. Oncol. , vol.19 , pp. 1774-1786
    • Amara, K.1    Trimeche, M.2    Ziadi, S.3    Laatiri, A.4    Hachana, M.5    Korbi, S.6
  • 4
    • 64249160168 scopus 로고    scopus 로고
    • DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: Its possible involvement in the formation of epigenetic field defect
    • Ando T., Yoshida T., Enomoto S., Asada K., Tatematsu M., Ichinose M., Sugiyama T., Ushijima T. DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: Its possible involvement in the formation of epigenetic field defect. Int. J. Cancer 2009, 124:2367-2374.
    • (2009) Int. J. Cancer , vol.124 , pp. 2367-2374
    • Ando, T.1    Yoshida, T.2    Enomoto, S.3    Asada, K.4    Tatematsu, M.5    Ichinose, M.6    Sugiyama, T.7    Ushijima, T.8
  • 5
    • 0033624862 scopus 로고    scopus 로고
    • Methylation status of the p15INK4B gene in hematopoietic progenitors and peripheral blood cells in myelodysplastic syndromes
    • Aoki E., Uchida T., Ohashi H., Nagai H., Murase T., Ichikawa A., Yamao K., Hotta T., Kinoshita T., Saito H., et al. Methylation status of the p15INK4B gene in hematopoietic progenitors and peripheral blood cells in myelodysplastic syndromes. Leukemia 2000, 14:586-593.
    • (2000) Leukemia , vol.14 , pp. 586-593
    • Aoki, E.1    Uchida, T.2    Ohashi, H.3    Nagai, H.4    Murase, T.5    Ichikawa, A.6    Yamao, K.7    Hotta, T.8    Kinoshita, T.9    Saito, H.10
  • 7
    • 73949123790 scopus 로고    scopus 로고
    • MicroRNA expression in head and neck cancer associates with alcohol consumption and survival
    • Avissar M., McClean M.D., Kelsey K.T., Marsit C.J. MicroRNA expression in head and neck cancer associates with alcohol consumption and survival. Carcinogenesis 2009, 30:2059-2063.
    • (2009) Carcinogenesis , vol.30 , pp. 2059-2063
    • Avissar, M.1    McClean, M.D.2    Kelsey, K.T.3    Marsit, C.J.4
  • 8
    • 65249186738 scopus 로고    scopus 로고
    • MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma
    • Avissar M., Christensen B.C., Kelsey K.T., Marsit C.J. MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma. Clin. Cancer Res. 2009, 15:2850-2855.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 2850-2855
    • Avissar, M.1    Christensen, B.C.2    Kelsey, K.T.3    Marsit, C.J.4
  • 9
    • 0037419739 scopus 로고    scopus 로고
    • P16 hypermethylation during gastric carcinogenesis of Wistar rats by N-methyl-N'-nitro-N-nitrosoguanidine
    • Bai H., Gu L.K., Zhou J., Deng D.J. p16 hypermethylation during gastric carcinogenesis of Wistar rats by N-methyl-N'-nitro-N-nitrosoguanidine. Mutat. Res. 2003, 535:73-78.
    • (2003) Mutat. Res. , vol.535 , pp. 73-78
    • Bai, H.1    Gu, L.K.2    Zhou, J.3    Deng, D.J.4
  • 10
    • 57649184758 scopus 로고    scopus 로고
    • Nucleosome positions and differential methylation status of various regions within the MLH1 CpG island
    • Bai H., Zhou J., Deng D.J. Nucleosome positions and differential methylation status of various regions within the MLH1 CpG island. Chin. J. Cancer Res. 2008, 20:237-242.
    • (2008) Chin. J. Cancer Res. , vol.20 , pp. 237-242
    • Bai, H.1    Zhou, J.2    Deng, D.J.3
  • 11
    • 0037389849 scopus 로고    scopus 로고
    • O6-methyl-guanine-DNA methyltransferase methylation in serum and tumor DNA predicts response to 1, 3-bis(2-chloroethyl)-1-nitrosourea but not to temozolamide plus cisplatin in glioblastoma multiforme
    • Balaña C., Ramirez J.L., Taron M., Roussos Y., Ariza A., Ballester R., Sarries C., Mendez P., Sanchez J.J., Rosell R. O6-methyl-guanine-DNA methyltransferase methylation in serum and tumor DNA predicts response to 1, 3-bis(2-chloroethyl)-1-nitrosourea but not to temozolamide plus cisplatin in glioblastoma multiforme. Clin. Cancer Res. 2003, 9:1461-1468.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1461-1468
    • Balaña, C.1    Ramirez, J.L.2    Taron, M.3    Roussos, Y.4    Ariza, A.5    Ballester, R.6    Sarries, C.7    Mendez, P.8    Sanchez, J.J.9    Rosell, R.10
  • 16
    • 0036119616 scopus 로고    scopus 로고
    • Aberrant CpG island methylation of the p16(INK4a) and estrogen receptor genes in rat lung tumors induced by particulate carcinogens
    • Belinsky S.A., Snow S.S., Nikula K.J., Finch G.L., Tellez C.S., Palmisano W.A. Aberrant CpG island methylation of the p16(INK4a) and estrogen receptor genes in rat lung tumors induced by particulate carcinogens. Carcinogenesis 2002, 23:335-339.
    • (2002) Carcinogenesis , vol.23 , pp. 335-339
    • Belinsky, S.A.1    Snow, S.S.2    Nikula, K.J.3    Finch, G.L.4    Tellez, C.S.5    Palmisano, W.A.6
  • 19
    • 33746359639 scopus 로고    scopus 로고
    • The death-associated protein kinases: Structure, function, and beyond
    • Bialik S., Kimchi A. The death-associated protein kinases: Structure, function, and beyond. Annu. Rev. Biochem. 2006, 75:189-210.
    • (2006) Annu. Rev. Biochem. , vol.75 , pp. 189-210
    • Bialik, S.1    Kimchi, A.2
  • 23
    • 12244297095 scopus 로고    scopus 로고
    • Quantitative O(6)-methylguanine DNA methyltransferase methylation analysis in curatively resected non-small cell lung cancer: associations with clinical outcome
    • Brabender J., Usadel H., Metzger R., Schneider P.M., Park J., Salonga D., Tsao-Wei D.D., Groshen S., Lord R.V., Takebe N., et al. Quantitative O(6)-methylguanine DNA methyltransferase methylation analysis in curatively resected non-small cell lung cancer: associations with clinical outcome. Clin. Cancer Res. 2003, 9:223-227.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 223-227
    • Brabender, J.1    Usadel, H.2    Metzger, R.3    Schneider, P.M.4    Park, J.5    Salonga, D.6    Tsao-Wei, D.D.7    Groshen, S.8    Lord, R.V.9    Takebe, N.10
  • 27
    • 77449124527 scopus 로고    scopus 로고
    • PTEN, RASSF1 and DAPK site-specific hypermethylation and outcome in surgically treated stage I and II nonsmall cell lung cancer patients
    • Buckingham L., Penfield F.L., Kim A., Liptay M., Barger C., Basu S., Fidler M., Walters K., Bonomi P., Coon J. PTEN, RASSF1 and DAPK site-specific hypermethylation and outcome in surgically treated stage I and II nonsmall cell lung cancer patients. Int. J. Cancer 2010, 126:1630-1639.
    • (2010) Int. J. Cancer , vol.126 , pp. 1630-1639
    • Buckingham, L.1    Penfield, F.L.2    Kim, A.3    Liptay, M.4    Barger, C.5    Basu, S.6    Fidler, M.7    Walters, K.8    Bonomi, P.9    Coon, J.10
  • 30
    • 69349084287 scopus 로고    scopus 로고
    • Methylation of p16 CpG island associated with malignant progression of oral epithelial dysplasia: A prospective cohort study
    • Cao J., Zhou J., Gao Y., Gu L., Meng H., Liu H., Deng D. Methylation of p16 CpG island associated with malignant progression of oral epithelial dysplasia: A prospective cohort study. Clin. Cancer Res. 2009, 15:5178-5183.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 5178-5183
    • Cao, J.1    Zhou, J.2    Gao, Y.3    Gu, L.4    Meng, H.5    Liu, H.6    Deng, D.7
  • 31
    • 36749092263 scopus 로고    scopus 로고
    • Assessment of MLH1 promoter methylation in relation to gene expression requires specific analysis
    • Capel E., Fléjou J.F., Hamelin R. Assessment of MLH1 promoter methylation in relation to gene expression requires specific analysis. Oncogene 2007, 26:7596-7600.
    • (2007) Oncogene , vol.26 , pp. 7596-7600
    • Capel, E.1    Fléjou, J.F.2    Hamelin, R.3
  • 33
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan J.A., Krichevsky A.M., Kosik K.S. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 2005, 65:6029-6033.
    • (2005) Cancer Res. , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 34
    • 0036894939 scopus 로고    scopus 로고
    • Correlation between insulin-like growth factor-binding protein-3 promoter methylation and prognosis of patients with stage I non-small cell lung cancer
    • Chang Y.S., Wang L., Liu D., Mao L., Hong W.K., Khuri F.R., Lee H.Y. Correlation between insulin-like growth factor-binding protein-3 promoter methylation and prognosis of patients with stage I non-small cell lung cancer. Clin. Cancer Res. 2002, 8:3669-3675.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 3669-3675
    • Chang, Y.S.1    Wang, L.2    Liu, D.3    Mao, L.4    Hong, W.K.5    Khuri, F.R.6    Lee, H.Y.7
  • 35
    • 0036316318 scopus 로고    scopus 로고
    • Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes
    • Chen H., Wu S. Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes. Chin. Med. J. (Engl.) 2002, 115:987-990.
    • (2002) Chin. Med. J. (Engl.) , vol.115 , pp. 987-990
    • Chen, H.1    Wu, S.2
  • 37
    • 53349177819 scopus 로고    scopus 로고
    • Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases
    • Chen X., Ba Y., Ma L., Cai X., Yin Y., Wang K., Guo J., Zhang Y., Chen J., Guo X., et al. Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 2008, 18:997-1006.
    • (2008) Cell Res. , vol.18 , pp. 997-1006
    • Chen, X.1    Ba, Y.2    Ma, L.3    Cai, X.4    Yin, Y.5    Wang, K.6    Guo, J.7    Zhang, Y.8    Chen, J.9    Guo, X.10
  • 39
    • 0035816267 scopus 로고    scopus 로고
    • Aneuploidy and prognosis of non-small-cell lung cancer: A meta-analysis of published data
    • Choma D., Daures J.P., Quantin X., Pujol J.L. Aneuploidy and prognosis of non-small-cell lung cancer: A meta-analysis of published data. Br. J. Cancer 2001, 85:14-22.
    • (2001) Br. J. Cancer , vol.85 , pp. 14-22
    • Choma, D.1    Daures, J.P.2    Quantin, X.3    Pujol, J.L.4
  • 41
    • 77950202790 scopus 로고    scopus 로고
    • Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers
    • Creighton C.J., Fountain M.D., Yu Z., Nagaraja A.K., Zhu H., Khan M., Olokpa E., Zariff A., Gunaratne P.H., Matzuk M.M., et al. Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers. Cancer Res. 2010, 70:1906-1915.
    • (2010) Cancer Res. , vol.70 , pp. 1906-1915
    • Creighton, C.J.1    Fountain, M.D.2    Yu, Z.3    Nagaraja, A.K.4    Zhu, H.5    Khan, M.6    Olokpa, E.7    Zariff, A.8    Gunaratne, P.H.9    Matzuk, M.M.10
  • 43
    • 33644815287 scopus 로고    scopus 로고
    • Factors involved in selfrenewal and pluripotency of embryonic stem cells
    • Darr H., Benvenisty N. Factors involved in selfrenewal and pluripotency of embryonic stem cells. Handb. Exp. Pharmacol. 2006, 174:1-19.
    • (2006) Handb. Exp. Pharmacol. , vol.174 , pp. 1-19
    • Darr, H.1    Benvenisty, N.2
  • 46
    • 0028831202 scopus 로고
    • Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death
    • Deiss L.P., Feinstein E., Berissi H., Cohen O., Kimchi A. Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev. 1995, 9:15-30.
    • (1995) Genes Dev. , vol.9 , pp. 15-30
    • Deiss, L.P.1    Feinstein, E.2    Berissi, H.3    Cohen, O.4    Kimchi, A.5
  • 48
    • 0033135049 scopus 로고    scopus 로고
    • Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression
    • Deng G., Chen A., Hong J., Chae H.S., Kim Y.S. Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression. Cancer Res. 1999, 59:2029-2033.
    • (1999) Cancer Res. , vol.59 , pp. 2029-2033
    • Deng, G.1    Chen, A.2    Hong, J.3    Chae, H.S.4    Kim, Y.S.5
  • 49
    • 0037065954 scopus 로고    scopus 로고
    • Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer
    • Deng G., Peng E., Gum J., Terdiman J., Sleisenger M., Kim Y.S. Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer. Br. J. Cancer 2002, 86:574-579.
    • (2002) Br. J. Cancer , vol.86 , pp. 574-579
    • Deng, G.1    Peng, E.2    Gum, J.3    Terdiman, J.4    Sleisenger, M.5    Kim, Y.S.6
  • 50
    • 0037439261 scopus 로고    scopus 로고
    • Silencing-specific methylation and single nucleotide polymorphism of hMLH1 promoter in gastric carcinomas
    • Deng D.J., Zhou J., Zhu B.D., Ji J.F., Harper J.C., Powell S.M. Silencing-specific methylation and single nucleotide polymorphism of hMLH1 promoter in gastric carcinomas. World J. Gastroenterol. 2003, 9:26-29.
    • (2003) World J. Gastroenterol. , vol.9 , pp. 26-29
    • Deng, D.J.1    Zhou, J.2    Zhu, B.D.3    Ji, J.F.4    Harper, J.C.5    Powell, S.M.6
  • 53
    • 0041353551 scopus 로고    scopus 로고
    • LINE-mediated retrotransposition of marked Alu sequences
    • Dewannieux M., Esnault C., Heidmann T. LINE-mediated retrotransposition of marked Alu sequences. Nat. Genet. 2003, 35:41-48.
    • (2003) Nat. Genet. , vol.35 , pp. 41-48
    • Dewannieux, M.1    Esnault, C.2    Heidmann, T.3
  • 54
    • 58249084931 scopus 로고    scopus 로고
    • Promoter methylation of p16 associated with Helicobacter pylori infection in precancerous gastric lesions: A population-based study
    • Dong C.X., Deng D.J., Pan K.F., Zhang L., Zhang Y., Zhou J., You W.C. Promoter methylation of p16 associated with Helicobacter pylori infection in precancerous gastric lesions: A population-based study. Int. J. Cancer 2009, 124:434-439.
    • (2009) Int. J. Cancer , vol.124 , pp. 434-439
    • Dong, C.X.1    Deng, D.J.2    Pan, K.F.3    Zhang, L.4    Zhang, Y.5    Zhou, J.6    You, W.C.7
  • 55
    • 77349116360 scopus 로고    scopus 로고
    • MicroRNAs and lung cancer: Tumors and 22-mers
    • Du L., Pertsemlidis A. microRNAs and lung cancer: Tumors and 22-mers. Cancer Metastasis Rev. 2010, 29:109-122.
    • (2010) Cancer Metastasis Rev. , vol.29 , pp. 109-122
    • Du, L.1    Pertsemlidis, A.2
  • 56
    • 0037068353 scopus 로고    scopus 로고
    • DNA methylation in cancer: Too much, but also too little
    • Ehrlich M. DNA methylation in cancer: Too much, but also too little. Oncogene 2002, 21:5400-5413.
    • (2002) Oncogene , vol.21 , pp. 5400-5413
    • Ehrlich, M.1
  • 58
    • 0037068312 scopus 로고    scopus 로고
    • CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
    • Esteller M. CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future. Oncogene 2002, 21:5427-5440.
    • (2002) Oncogene , vol.21 , pp. 5427-5440
    • Esteller, M.1
  • 59
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat. Rev. Genet. 2007, 8:286-298.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 286-298
    • Esteller, M.1
  • 60
    • 0033557903 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • Esteller M., Hamilton S.R., Burger P.C., Baylin S.B., Herman J.G. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res. 1999, 59:793-797.
    • (1999) Cancer Res. , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 63
    • 4544254849 scopus 로고    scopus 로고
    • Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas
    • Ferreri A.J., Dell'Oro S., Capello D., Ponzoni M., Iuzzolino P., Rossi D., Pasini F., Ambrosetti A., Orvieto E., Ferrarese F., et al. Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas. Br. J. Haematol. 2004, 126:657-664.
    • (2004) Br. J. Haematol. , vol.126 , pp. 657-664
    • Ferreri, A.J.1    Dell'Oro, S.2    Capello, D.3    Ponzoni, M.4    Iuzzolino, P.5    Rossi, D.6    Pasini, F.7    Ambrosetti, A.8    Orvieto, E.9    Ferrarese, F.10
  • 64
    • 31544435739 scopus 로고    scopus 로고
    • Breast cancer DNA methylation profiles in cancer cells and tumor stroma: Association with HER-2/neu status in primary breast cancer
    • Fiegl H., Millinger S., Goebel G., Muller-Holzner E., Marth C., Laird P.W., Widschwendter M. Breast cancer DNA methylation profiles in cancer cells and tumor stroma: Association with HER-2/neu status in primary breast cancer. Cancer Res. 2006, 66:29-33.
    • (2006) Cancer Res. , vol.66 , pp. 29-33
    • Fiegl, H.1    Millinger, S.2    Goebel, G.3    Muller-Holzner, E.4    Marth, C.5    Laird, P.W.6    Widschwendter, M.7
  • 67
    • 77954315239 scopus 로고    scopus 로고
    • Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis
    • 10.1016/j.biopha.2010.01.018
    • Gao W., Yu Y., Cao H., Shen H., Li X., Pan S., Shu Y. Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis. Biomed. Pharmacother. 2010, 10.1016/j.biopha.2010.01.018.
    • (2010) Biomed. Pharmacother.
    • Gao, W.1    Yu, Y.2    Cao, H.3    Shen, H.4    Li, X.5    Pan, S.6    Shu, Y.7
  • 68
    • 1942469956 scopus 로고    scopus 로고
    • MGMT: Its role in cancer aetiology and cancer therapeutics
    • Gerson S.L. MGMT: Its role in cancer aetiology and cancer therapeutics. Nat. Rev. Cancer 2004, 4:296-307.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 296-307
    • Gerson, S.L.1
  • 69
    • 3042774430 scopus 로고    scopus 로고
    • The acquisition of hMLH1 methylation in plasma DNA after chemotherapy predicts poor survival for ovarian cancer patients
    • Gifford G., Paul J., Vasey P.A., Kaye S.B., Brown R. The acquisition of hMLH1 methylation in plasma DNA after chemotherapy predicts poor survival for ovarian cancer patients. Clin. Cancer Res. 2004, 10:4420-4426.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 4420-4426
    • Gifford, G.1    Paul, J.2    Vasey, P.A.3    Kaye, S.B.4    Brown, R.5
  • 70
    • 0141995080 scopus 로고    scopus 로고
    • Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas
    • Girault I., Tozlu S., Lidereau R., Bièche I. Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas. Clin. Cancer Res. 2003, 9:4415-4422.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 4415-4422
    • Girault, I.1    Tozlu, S.2    Lidereau, R.3    Bièche, I.4
  • 71
    • 0037817323 scopus 로고    scopus 로고
    • Prostate cancer detection by GSTP1 methylation analysis of postbiopsy urine specimens
    • Gonzalgo M.L., Pavlovich C.P., Lee S.M., Nelson W.G. Prostate cancer detection by GSTP1 methylation analysis of postbiopsy urine specimens. Clin. Cancer Res. 2003, 9:2673-2677.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2673-2677
    • Gonzalgo, M.L.1    Pavlovich, C.P.2    Lee, S.M.3    Nelson, W.G.4
  • 74
    • 0029803785 scopus 로고    scopus 로고
    • Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes
    • Grombacher T., Mitra S., Kaina B. Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes. Carcinogenesis 1996, 17:2329-2336.
    • (1996) Carcinogenesis , vol.17 , pp. 2329-2336
    • Grombacher, T.1    Mitra, S.2    Kaina, B.3
  • 77
    • 65549127199 scopus 로고    scopus 로고
    • Genetic imprinting: The paradigm of Prader-Willi and Angelman syndromes
    • Gurrieri F., Accadia M. Genetic imprinting: The paradigm of Prader-Willi and Angelman syndromes. Endocr. Dev. 2009, 14:20-28.
    • (2009) Endocr. Dev. , vol.14 , pp. 20-28
    • Gurrieri, F.1    Accadia, M.2
  • 78
    • 7944228563 scopus 로고    scopus 로고
    • The pathobiology of the septin gene family
    • Hall P.A., Russell S.E. The pathobiology of the septin gene family. J. Pathol. 2004, 204:489-505.
    • (2004) J. Pathol. , vol.204 , pp. 489-505
    • Hall, P.A.1    Russell, S.E.2
  • 79
    • 21344446835 scopus 로고    scopus 로고
    • Expression profiling the human septin gene family
    • Hall P.A., Jung K., Hillan K.J., Russell S.E. Expression profiling the human septin gene family. J. Pathol. 2005, 206:269-278.
    • (2005) J. Pathol. , vol.206 , pp. 269-278
    • Hall, P.A.1    Jung, K.2    Hillan, K.J.3    Russell, S.E.4
  • 82
    • 12144291692 scopus 로고    scopus 로고
    • Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide
    • Hegi M.E., Diserens A.C., Godard S., Dietrich P.Y., Regli L., Ostermann S., Otten P., Van Melle G., de Tribolet N., Stupp R. Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin. Cancer Res. 2004, 10:1871-1874.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 1871-1874
    • Hegi, M.E.1    Diserens, A.C.2    Godard, S.3    Dietrich, P.Y.4    Regli, L.5    Ostermann, S.6    Otten, P.7    Van Melle, G.8    de Tribolet, N.9    Stupp, R.10
  • 84
    • 67651158856 scopus 로고    scopus 로고
    • Methylation of helicase-like transcription factor in serum of patients with colorectal cancer is an independent predictor of disease recurrence
    • Herbst A., Wallner M., Rahmig K., Stieber P., Crispin A., Lamerz R., Kolligs F.T. Methylation of helicase-like transcription factor in serum of patients with colorectal cancer is an independent predictor of disease recurrence. Eur. J. Gastroenterol. Hepatol. 2009, 21:565-569.
    • (2009) Eur. J. Gastroenterol. Hepatol. , vol.21 , pp. 565-569
    • Herbst, A.1    Wallner, M.2    Rahmig, K.3    Stieber, P.4    Crispin, A.5    Lamerz, R.6    Kolligs, F.T.7
  • 85
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman J.G., Baylin S.B. Gene silencing in cancer in association with promoter hypermethylation. N Engl J. Med. 2003, 349:2042-2054.
    • (2003) N Engl J. Med. , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 88
    • 72749085056 scopus 로고    scopus 로고
    • Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer
    • Hitchins M.P., Ward R.L. Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer. J. Med. Genet. 2009, 46:793-802.
    • (2009) J. Med. Genet. , vol.46 , pp. 793-802
    • Hitchins, M.P.1    Ward, R.L.2
  • 93
    • 0042442335 scopus 로고    scopus 로고
    • Embryonic stem cell-specific MicroRNAs
    • Houbaviy H.B., Murray M.F., Sharp P.A. Embryonic stem cell-specific MicroRNAs. Dev. Cell 2003, 5:351-358.
    • (2003) Dev. Cell , vol.5 , pp. 351-358
    • Houbaviy, H.B.1    Murray, M.F.2    Sharp, P.A.3
  • 95
    • 77957350469 scopus 로고    scopus 로고
    • Natural History of low-grade cervical intraepithelial neoplasia and its relationship with p16 hypermethylation
    • Hu S., Wang X., Zhou J., Chen F., Zhang X., Chen W., Pan Q., Zhao F., Deng D., Qiao Y. Natural History of low-grade cervical intraepithelial neoplasia and its relationship with p16 hypermethylation. Chin. Cancer 2009, 18:420-423.
    • (2009) Chin. Cancer , vol.18 , pp. 420-423
    • Hu, S.1    Wang, X.2    Zhou, J.3    Chen, F.4    Zhang, X.5    Chen, W.6    Pan, Q.7    Zhao, F.8    Deng, D.9    Qiao, Y.10
  • 96
    • 68249160070 scopus 로고    scopus 로고
    • Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression
    • Iliopoulos D., Oikonomou P., Messinis I., Tsezou A. Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression. Oncol. Rep. 2009, 22:199-204.
    • (2009) Oncol. Rep. , vol.22 , pp. 199-204
    • Iliopoulos, D.1    Oikonomou, P.2    Messinis, I.3    Tsezou, A.4
  • 97
    • 0037193474 scopus 로고    scopus 로고
    • DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
    • Inbal B., Bialik S., Sabanay I., Shani G., Kimchi A. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J. Cell Biol. 2002, 157:455-468.
    • (2002) J. Cell Biol. , vol.157 , pp. 455-468
    • Inbal, B.1    Bialik, S.2    Sabanay, I.3    Shani, G.4    Kimchi, A.5
  • 98
    • 56949084876 scopus 로고    scopus 로고
    • MicroRNA profiling as a tool to understand prognosis, therapy response and resistance in breast cancer
    • Iorio M.V., Casalini P., Tagliabue E., Ménard S., Croce C.M. MicroRNA profiling as a tool to understand prognosis, therapy response and resistance in breast cancer. Eur. J. Cancer 2008, 44:2753-2759.
    • (2008) Eur. J. Cancer , vol.44 , pp. 2753-2759
    • Iorio, M.V.1    Casalini, P.2    Tagliabue, E.3    Ménard, S.4    Croce, C.M.5
  • 100
    • 10344260184 scopus 로고    scopus 로고
    • CpG island methylator phenotype in cancer
    • Issa J.P. CpG island methylator phenotype in cancer. Nat. Rev. Cancer 2004, 4:988-993.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 988-993
    • Issa, J.P.1
  • 103
    • 52549088093 scopus 로고    scopus 로고
    • Promoter hypermethylation in tumour suppressor genes shows association with stage, grade and invasiveness of bladder cancer
    • Jarmalaite S., Jankevicius F., Kurgonaite K., Suziedelis K., Mutanen P., Husgafvel-Pursiainen K. Promoter hypermethylation in tumour suppressor genes shows association with stage, grade and invasiveness of bladder cancer. Oncology 2008, 75:145-151.
    • (2008) Oncology , vol.75 , pp. 145-151
    • Jarmalaite, S.1    Jankevicius, F.2    Kurgonaite, K.3    Suziedelis, K.4    Mutanen, P.5    Husgafvel-Pursiainen, K.6
  • 106
    • 33745728247 scopus 로고    scopus 로고
    • Persistent infection of hepatitis B virus is involved in high rate of p16 methylation in hepatocellular carcinoma
    • Jicai Z., Zongtao Y., Jun L., Haiping L., Jianmin W., Lihua H. Persistent infection of hepatitis B virus is involved in high rate of p16 methylation in hepatocellular carcinoma. Mol. Carcinog. 2006, 45:530-536.
    • (2006) Mol. Carcinog. , vol.45 , pp. 530-536
    • Jicai, Z.1    Zongtao, Y.2    Jun, L.3    Haiping, L.4    Jianmin, W.5    Lihua, H.6
  • 107
    • 66249114998 scopus 로고    scopus 로고
    • A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus
    • Jin Z., Cheng Y., Gu W., Zheng Y., Sato F., Mori Y., Olaru A.V., Paun B.C., Yang J., Kan T., et al. A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus. Cancer Res. 2009, 69:4112-4115.
    • (2009) Cancer Res. , vol.69 , pp. 4112-4115
    • Jin, Z.1    Cheng, Y.2    Gu, W.3    Zheng, Y.4    Sato, F.5    Mori, Y.6    Olaru, A.V.7    Paun, B.C.8    Yang, J.9    Kan, T.10
  • 108
    • 0034008329 scopus 로고    scopus 로고
    • Genomic and expression analyses of alternatively spliced transcripts of the MLL septin-like fusion gene (MSF) that map to a 17q25 region of loss in breast and ovarian tumors
    • Kalikin L.M., Sims H.L., Petty E.M. Genomic and expression analyses of alternatively spliced transcripts of the MLL septin-like fusion gene (MSF) that map to a 17q25 region of loss in breast and ovarian tumors. Genomics 2000, 63:165-172.
    • (2000) Genomics , vol.63 , pp. 165-172
    • Kalikin, L.M.1    Sims, H.L.2    Petty, E.M.3
  • 112
    • 0037047398 scopus 로고    scopus 로고
    • LINE drive. retrotransposition and genome instability
    • Kazazian H.H., Goodier J.L. LINE drive. retrotransposition and genome instability. Cell 2002, 110:277-280.
    • (2002) Cell , vol.110 , pp. 277-280
    • Kazazian, H.H.1    Goodier, J.L.2
  • 113
    • 0029975913 scopus 로고    scopus 로고
    • Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity
    • Khleif S.N., DeGregori J., Yee C.L., Otterson G.A., Kaye F.J., Nevins J.R., Howley P.M. Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proc. Natl. Acad. Sci. USA 1996, 93:4350-4354.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4350-4354
    • Khleif, S.N.1    DeGregori, J.2    Yee, C.L.3    Otterson, G.A.4    Kaye, F.J.5    Nevins, J.R.6    Howley, P.M.7
  • 114
    • 0035967107 scopus 로고    scopus 로고
    • Promoter methylation of DAP-kinase: Association with advanced stage in non-small cell lung cancer
    • Kim D.H., Nelson H.H., Wiencke J.K., Christiani D.C., Wain J.C., Mark E.J., Kelsey K.T. Promoter methylation of DAP-kinase: Association with advanced stage in non-small cell lung cancer. Oncogene 2001, 20:1765-1770.
    • (2001) Oncogene , vol.20 , pp. 1765-1770
    • Kim, D.H.1    Nelson, H.H.2    Wiencke, J.K.3    Christiani, D.C.4    Wain, J.C.5    Mark, E.J.6    Kelsey, K.T.7
  • 115
    • 37049001894 scopus 로고    scopus 로고
    • Aberrant methylation of E-cadherin and H-cadherin genes in nonsmall cell lung cancer and its relation to clinicopathologic features
    • Kim D.S., Kim M.J., Lee J.Y., Kim Y.Z., Kim E.J., Park J.Y. Aberrant methylation of E-cadherin and H-cadherin genes in nonsmall cell lung cancer and its relation to clinicopathologic features. Cancer 2007, 110:2785-2792.
    • (2007) Cancer , vol.110 , pp. 2785-2792
    • Kim, D.S.1    Kim, M.J.2    Lee, J.Y.3    Kim, Y.Z.4    Kim, E.J.5    Park, J.Y.6
  • 116
    • 48649097939 scopus 로고    scopus 로고
    • Methylation of the RUNX3 promoter as a potential prognostic marker for bladder tumor
    • Kim E.J., Kim Y.J., Jeong P., Ha Y.S., Bae S.C., Kim W.J. Methylation of the RUNX3 promoter as a potential prognostic marker for bladder tumor. J. Urol. 2008, 180:1141-1145.
    • (2008) J. Urol. , vol.180 , pp. 1141-1145
    • Kim, E.J.1    Kim, Y.J.2    Jeong, P.3    Ha, Y.S.4    Bae, S.C.5    Kim, W.J.6
  • 117
    • 77349107376 scopus 로고    scopus 로고
    • DNA methylation markers in colorectal cancer
    • Kim M.S., Lee J., Sidransky D. DNA methylation markers in colorectal cancer. Cancer Metastasis Rev. 2010, 29:181-206.
    • (2010) Cancer Metastasis Rev. , vol.29 , pp. 181-206
    • Kim, M.S.1    Lee, J.2    Sidransky, D.3
  • 119
    • 77952920881 scopus 로고    scopus 로고
    • Secretory mechanisms and intercellular transfer of microRNAs in living cells
    • 10.1074/jbc.M110.107821
    • Kosaka N., Iguchi H., Yoshioka Y., Takeshita F., Matsuki Y., Ochiya T. Secretory mechanisms and intercellular transfer of microRNAs in living cells. J. Biol. Chem. 2010, 10.1074/jbc.M110.107821.
    • (2010) J. Biol. Chem.
    • Kosaka, N.1    Iguchi, H.2    Yoshioka, Y.3    Takeshita, F.4    Matsuki, Y.5    Ochiya, T.6
  • 127
    • 0033214928 scopus 로고    scopus 로고
    • Targeted mutagenesis of Tsix leads to nonrandom X inactivation
    • Lee J.T., Lu N. Targeted mutagenesis of Tsix leads to nonrandom X inactivation. Cell 1999, 99:47-57.
    • (1999) Cell , vol.99 , pp. 47-57
    • Lee, J.T.1    Lu, N.2
  • 130
    • 0033950894 scopus 로고    scopus 로고
    • Frequent methylation of estrogen receptor in prostate cancer: correlation with tumor progression
    • Li L.C., Chui R., Nakajima K., Oh B.R., Au H.C., Dahiya R. Frequent methylation of estrogen receptor in prostate cancer: correlation with tumor progression. Cancer Res. 2000, 60:702-706.
    • (2000) Cancer Res. , vol.60 , pp. 702-706
    • Li, L.C.1    Chui, R.2    Nakajima, K.3    Oh, B.R.4    Au, H.C.5    Dahiya, R.6
  • 131
    • 47949123984 scopus 로고    scopus 로고
    • Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung
    • Licchesi J.D., Westra W.H., Hooker C.M., Herman J.G. Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung. Clin. Cancer Res. 2008, 14:2570-2578.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 2570-2578
    • Licchesi, J.D.1    Westra, W.H.2    Hooker, C.M.3    Herman, J.G.4
  • 132
    • 33846111256 scopus 로고    scopus 로고
    • Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer
    • Lin R.K., Hsu H.S., Chang J.W., Chen C.Y., Chen J.T., Wang Y.C. Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer. Lung Cancer 2007, 55:205-213.
    • (2007) Lung Cancer , vol.55 , pp. 205-213
    • Lin, R.K.1    Hsu, H.S.2    Chang, J.W.3    Chen, C.Y.4    Chen, J.T.5    Wang, Y.C.6
  • 134
    • 34548080580 scopus 로고    scopus 로고
    • Promoter hypermethylation of the p16 gene in pre- and post-gastrectomy plasma of patients with gastric carcinoma
    • Liu Y., Zhang L., Ren H., Zhang G., Qin F., Kong G., Deng G., Ji J. Promoter hypermethylation of the p16 gene in pre- and post-gastrectomy plasma of patients with gastric carcinoma. J. Peking Univ. Health Sci. 2005, 37:257-260.
    • (2005) J. Peking Univ. Health Sci. , vol.37 , pp. 257-260
    • Liu, Y.1    Zhang, L.2    Ren, H.3    Zhang, G.4    Qin, F.5    Kong, G.6    Deng, G.7    Ji, J.8
  • 135
    • 77957058258 scopus 로고    scopus 로고
    • Quantitative detection of multiple gene promoter hypermethylation in tumor tissue, serum, and cerebrospinal fluid predicts prognosis of malignant gliomas
    • 10.1093/neuonc/nop064
    • Liu B.L., Cheng J.X., Zhang W., Zhang X., Wang R., Lin H., Huo J.L., Cheng H. Quantitative detection of multiple gene promoter hypermethylation in tumor tissue, serum, and cerebrospinal fluid predicts prognosis of malignant gliomas. Neuro Oncol. 2010, 10.1093/neuonc/nop064.
    • (2010) Neuro Oncol.
    • Liu, B.L.1    Cheng, J.X.2    Zhang, W.3    Zhang, X.4    Wang, R.5    Lin, H.6    Huo, J.L.7    Cheng, H.8
  • 136
    • 77950466208 scopus 로고    scopus 로고
    • Increase of microRNA miR-31 level in plasma could be a potential marker of oral cancer
    • 10.1111/j.1601-0825.2009.01646.x
    • Liu C.J., Kao S.Y., Tu H.F., Tsai M.M., Chang K.W., Lin S.C. Increase of microRNA miR-31 level in plasma could be a potential marker of oral cancer. Oral Dis. 2010, 10.1111/j.1601-0825.2009.01646.x.
    • (2010) Oral Dis.
    • Liu, C.J.1    Kao, S.Y.2    Tu, H.F.3    Tsai, M.M.4    Chang, K.W.5    Lin, S.C.6
  • 137
    • 76749131605 scopus 로고    scopus 로고
    • MiR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma
    • Liu C.J., Tsai M.M., Hung P.S., Kao S.Y., Liu T.Y., Wu K.J., Chiou S.H., Lin S.C., Chang K.W. miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma. Cancer Res. 2010, 70:1635-1644.
    • (2010) Cancer Res. , vol.70 , pp. 1635-1644
    • Liu, C.J.1    Tsai, M.M.2    Hung, P.S.3    Kao, S.Y.4    Liu, T.Y.5    Wu, K.J.6    Chiou, S.H.7    Lin, S.C.8    Chang, K.W.9
  • 138
    • 77951154173 scopus 로고    scopus 로고
    • MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors
    • Liu X., Sempere L.F., Ouyang H., Memoli V.A., Andrew A.S., Luo Y., Demidenko E., Korc M., Shi W., Preis M., et al. MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. J. Clin. Invest. 2010, 120:1298-1309.
    • (2010) J. Clin. Invest. , vol.120 , pp. 1298-1309
    • Liu, X.1    Sempere, L.F.2    Ouyang, H.3    Memoli, V.A.4    Andrew, A.S.5    Luo, Y.6    Demidenko, E.7    Korc, M.8    Shi, W.9    Preis, M.10
  • 142
    • 16544386625 scopus 로고    scopus 로고
    • Prognostic factors in resected stage I non-small-cell lung cancer: A multivariate analysis of six molecular markers
    • Lu C., Soria J.C., Tang X., Xu X.C., Wang L., Mao L., Lotan R., Kemp B., Bekele B.N., Feng L., et al. Prognostic factors in resected stage I non-small-cell lung cancer: A multivariate analysis of six molecular markers. J. Clin. Oncol. 2004, 22:4575-4583.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 4575-4583
    • Lu, C.1    Soria, J.C.2    Tang, X.3    Xu, X.C.4    Wang, L.5    Mao, L.6    Lotan, R.7    Kemp, B.8    Bekele, B.N.9    Feng, L.10
  • 144
    • 35948993791 scopus 로고    scopus 로고
    • Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable prognosis
    • Lu L., Katsaros D., de la Longrais I.A., Sochirca O., Yu H. Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable prognosis. Cancer Res. 2007, 67:10117-10122.
    • (2007) Cancer Res. , vol.67 , pp. 10117-10122
    • Lu, L.1    Katsaros, D.2    de la Longrais, I.A.3    Sochirca, O.4    Yu, H.5
  • 146
    • 33646871766 scopus 로고    scopus 로고
    • Methylation of CpG islands of p16 associated with progression of primary gastric carcinomas
    • Luo D., Zhang B., Lv L., Xiang S., Liu Y., Ji J., Deng D. Methylation of CpG islands of p16 associated with progression of primary gastric carcinomas. Lab. Invest. 2006, 86:591-598.
    • (2006) Lab. Invest. , vol.86 , pp. 591-598
    • Luo, D.1    Zhang, B.2    Lv, L.3    Xiang, S.4    Liu, Y.5    Ji, J.6    Deng, D.7
  • 151
    • 0029929885 scopus 로고    scopus 로고
    • Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment
    • Mao L., Lee J.S., Fan Y.H., Ro J.Y., Batsakis J.G., Lippman S., Hittelman W., Hong W.K. Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment. Nat. Med. 1996, 2:682-685.
    • (1996) Nat. Med. , vol.2 , pp. 682-685
    • Mao, L.1    Lee, J.S.2    Fan, Y.H.3    Ro, J.Y.4    Batsakis, J.G.5    Lippman, S.6    Hittelman, W.7    Hong, W.K.8
  • 152
    • 54049115558 scopus 로고    scopus 로고
    • Prognostic value of mature microRNA-21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative real-time RT-PCR
    • Markou A., Tsaroucha E.G., Kaklamanis L., Fotinou M., Georgoulias V., Lianidou E.S. Prognostic value of mature microRNA-21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative real-time RT-PCR. Clin. Chem. 2008, 54:1696-1704.
    • (2008) Clin. Chem. , vol.54 , pp. 1696-1704
    • Markou, A.1    Tsaroucha, E.G.2    Kaklamanis, L.3    Fotinou, M.4    Georgoulias, V.5    Lianidou, E.S.6
  • 153
    • 1642400575 scopus 로고    scopus 로고
    • Hypermethylation of FHIT as a prognostic marker in nonsmall cell lung carcinoma
    • Maruyama R., Sugio K., Yoshino I., Maehara Y., Gazdar A.F. Hypermethylation of FHIT as a prognostic marker in nonsmall cell lung carcinoma. Cancer 2004, 100:1472-1477.
    • (2004) Cancer , vol.100 , pp. 1472-1477
    • Maruyama, R.1    Sugio, K.2    Yoshino, I.3    Maehara, Y.4    Gazdar, A.F.5
  • 156
    • 0032924622 scopus 로고    scopus 로고
    • P16 (INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma
    • Matsuda Y., Ichida T., Matsuzawa J., Sugimura K., Asakura H. p16 (INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma. Gastroenterology 1999, 116:394-400.
    • (1999) Gastroenterology , vol.116 , pp. 394-400
    • Matsuda, Y.1    Ichida, T.2    Matsuzawa, J.3    Sugimura, K.4    Asakura, H.5
  • 157
    • 67449113768 scopus 로고    scopus 로고
    • Cancer DNA methylation: Molecular mechanisms and clinical implications
    • McCabe M.T., Brandes J.C., Vertino P.M. Cancer DNA methylation: Molecular mechanisms and clinical implications. Clin. Cancer Res. 2009, 15:3927-3937.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 3927-3937
    • McCabe, M.T.1    Brandes, J.C.2    Vertino, P.M.3
  • 158
    • 34447341733 scopus 로고    scopus 로고
    • Translational control of SEPT9 isoforms is perturbed in disease
    • McDade S.S., Hall P.A., Russell S.E. Translational control of SEPT9 isoforms is perturbed in disease. Hum. Mol. Genet. 2007, 16:742-752.
    • (2007) Hum. Mol. Genet. , vol.16 , pp. 742-752
    • McDade, S.S.1    Hall, P.A.2    Russell, S.E.3
  • 161
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F., Henson R., Wehbe-Janek H., Ghoshal K., Jacob S.T., Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007, 133:647-658.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 162
    • 60149109392 scopus 로고    scopus 로고
    • Normal colorectal mucosa exhibits sex- and segment-specific susceptibility to DNA methylation at the hMLH1 and MGMT promoters
    • Menigatti M., Truninger K., Gebbers J.O., Marbet U., Marra G., Schär P. Normal colorectal mucosa exhibits sex- and segment-specific susceptibility to DNA methylation at the hMLH1 and MGMT promoters. Oncogene 2009, 28:899-909.
    • (2009) Oncogene , vol.28 , pp. 899-909
    • Menigatti, M.1    Truninger, K.2    Gebbers, J.O.3    Marbet, U.4    Marra, G.5    Schär, P.6
  • 163
    • 0029011539 scopus 로고
    • 5-prime CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A., Herman J.G., Mao L., Lee D.J., Gabrielson E., Burger P.C., Baylin S.B., Sidransky D. 5-prime CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med. 1995, 1:686-692.
    • (1995) Nat. Med. , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 164
    • 73649118820 scopus 로고    scopus 로고
    • Death-associated protein kinase (DAPK) and signal transduction: Regulation in cancer
    • Michie A.M., McCaig A.M., Nakagawa R., Vukovic M. Death-associated protein kinase (DAPK) and signal transduction: Regulation in cancer. FEBS J. 2010, 277:74-80.
    • (2010) FEBS J. , vol.277 , pp. 74-80
    • Michie, A.M.1    McCaig, A.M.2    Nakagawa, R.3    Vukovic, M.4
  • 167
    • 34748900060 scopus 로고    scopus 로고
    • Hypermethylation of p14 (ARF) may be predictive of colitic cancer in patients with ulcerative colitis
    • Moriyama T., Matsumoto T., Nakamura S., Jo Y., Mibu R., Yao T., Iida M. Hypermethylation of p14 (ARF) may be predictive of colitic cancer in patients with ulcerative colitis. Dis. Colon Rectum 2007, 50:1384-1392.
    • (2007) Dis. Colon Rectum , vol.50 , pp. 1384-1392
    • Moriyama, T.1    Matsumoto, T.2    Nakamura, S.3    Jo, Y.4    Mibu, R.5    Yao, T.6    Iida, M.7
  • 170
    • 33645012544 scopus 로고    scopus 로고
    • Overgrowth caused by misexpression of a microRNA with dispensable wild-type function
    • Nairz K., Rottig C., Rintelen F., Zdobnov E., Moser M., Hafen E. Overgrowth caused by misexpression of a microRNA with dispensable wild-type function. Dev. Biol. 2006, 291:314-324.
    • (2006) Dev. Biol. , vol.291 , pp. 314-324
    • Nairz, K.1    Rottig, C.2    Rintelen, F.3    Zdobnov, E.4    Moser, M.5    Hafen, E.6
  • 174
    • 66049112674 scopus 로고    scopus 로고
    • Differential expression of microRNAs in plasma of patients with colorectal cancer: A potential marker for colorectal cancer screening
    • Ng E.K., Chong W.W., Jin H., Lam E.K., Shin V.Y., Yu J., Poon T.C., Ng S.S., Sung J.J. Differential expression of microRNAs in plasma of patients with colorectal cancer: A potential marker for colorectal cancer screening. Gut 2009, 58:1375-1381.
    • (2009) Gut , vol.58 , pp. 1375-1381
    • Ng, E.K.1    Chong, W.W.2    Jin, H.3    Lam, E.K.4    Shin, V.Y.5    Yu, J.6    Poon, T.C.7    Ng, S.S.8    Sung, J.J.9
  • 178
    • 0033607147 scopus 로고    scopus 로고
    • In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis
    • Nuovo G.J., Plaia T.W., Belinsky S.A., Baylin S.B., Herman J.G. In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis. Proc. Natl. Acad. Sci. USA 1999, 96:12754-12759.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 12754-12759
    • Nuovo, G.J.1    Plaia, T.W.2    Belinsky, S.A.3    Baylin, S.B.4    Herman, J.G.5
  • 180
    • 34548074239 scopus 로고    scopus 로고
    • DNA methyltransferase expression and DNA methylation in human hepatocellular carcinoma and their clinicopathological correlation
    • Oh B.K., Kim H., Park H.J., Shim Y.H., Choi J., Park C., Park Y.N. DNA methyltransferase expression and DNA methylation in human hepatocellular carcinoma and their clinicopathological correlation. Int. J. Mol. Med. 2007, 20:65-73.
    • (2007) Int. J. Mol. Med. , vol.20 , pp. 65-73
    • Oh, B.K.1    Kim, H.2    Park, H.J.3    Shim, Y.H.4    Choi, J.5    Park, C.6    Park, Y.N.7
  • 181
    • 41349083325 scopus 로고    scopus 로고
    • Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia
    • Oki Y., Jelinek J., Shen L., Kantarjian H.M., Issa J.P. Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia. Blood 2008, 111:2382-2384.
    • (2008) Blood , vol.111 , pp. 2382-2384
    • Oki, Y.1    Jelinek, J.2    Shen, L.3    Kantarjian, H.M.4    Issa, J.P.5
  • 182
  • 183
    • 33750724417 scopus 로고    scopus 로고
    • Prognostic significance of p16(INK4a) hypermethylation in non-small cell lung cancer is evident by quantitative DNA methylation analysis
    • Ota N., Kawakami K., Okuda T., Takehara A., Hiranuma C., Oyama K., Ota Y., Oda M., Watanabe G. Prognostic significance of p16(INK4a) hypermethylation in non-small cell lung cancer is evident by quantitative DNA methylation analysis. Anticancer Res. 2006, 26:3729-3732.
    • (2006) Anticancer Res. , vol.26 , pp. 3729-3732
    • Ota, N.1    Kawakami, K.2    Okuda, T.3    Takehara, A.4    Hiranuma, C.5    Oyama, K.6    Ota, Y.7    Oda, M.8    Watanabe, G.9
  • 187
  • 188
    • 39649119288 scopus 로고    scopus 로고
    • The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma
    • Pfister S., Rea S., Taipale M., Mendrzyk F., Straub B., Ittrich C., Thuerigen O., Sinn H.P., Akhtar A., Lichter P. The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma. Int. J. Cancer 2008, 122:1207-1213.
    • (2008) Int. J. Cancer , vol.122 , pp. 1207-1213
    • Pfister, S.1    Rea, S.2    Taipale, M.3    Mendrzyk, F.4    Straub, B.5    Ittrich, C.6    Thuerigen, O.7    Sinn, H.P.8    Akhtar, A.9    Lichter, P.10
  • 189
    • 0037058663 scopus 로고    scopus 로고
    • De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats
    • Pogribny I.P., James S.J. De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats. Cancer Lett. 2002, 187:69-75.
    • (2002) Cancer Lett. , vol.187 , pp. 69-75
    • Pogribny, I.P.1    James, S.J.2
  • 192
    • 0032523011 scopus 로고    scopus 로고
    • Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression
    • Quesnel B., Guillerm G., Vereecque R., Wattel E., Preudhomme C., Bauters F., Vanrumbeke M., Fenaux P. Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression. Blood 1998, 91:2985-2990.
    • (1998) Blood , vol.91 , pp. 2985-2990
    • Quesnel, B.1    Guillerm, G.2    Vereecque, R.3    Wattel, E.4    Preudhomme, C.5    Bauters, F.6    Vanrumbeke, M.7    Fenaux, P.8
  • 196
    • 67651002796 scopus 로고    scopus 로고
    • MicroRNA classifiers for predicting prognosis of squamous cell lung cancer
    • Raponi M., Dossey L., Jatkoe T., Wu X., Chen G., Fan H., Beer D.G. MicroRNA classifiers for predicting prognosis of squamous cell lung cancer. Cancer Res. 2009, 69:5776-5783.
    • (2009) Cancer Res. , vol.69 , pp. 5776-5783
    • Raponi, M.1    Dossey, L.2    Jatkoe, T.3    Wu, X.4    Chen, G.5    Fan, H.6    Beer, D.G.7
  • 197
    • 0034652165 scopus 로고    scopus 로고
    • A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activity
    • Raveh T., Berissi H., Eisenstein M., Spivak T., Kimchi A. A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activity. Proc. Natl. Acad. Sci. USA 2000, 97:1572-1577.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1572-1577
    • Raveh, T.1    Berissi, H.2    Eisenstein, M.3    Spivak, T.4    Kimchi, A.5
  • 198
    • 0035141040 scopus 로고    scopus 로고
    • DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation
    • Raveh T., Droguett G., Horwitz M.S., DePinho R.A., Kimchi A. DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation. Nat. Cell Biol. 2001, 3:1-7.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 1-7
    • Raveh, T.1    Droguett, G.2    Horwitz, M.S.3    DePinho, R.A.4    Kimchi, A.5
  • 200
    • 75849146316 scopus 로고    scopus 로고
    • MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma
    • Rivera A.L., Pelloski C.E., Gilbert M.R., Colman H., De La Cruz C., Sulman E.P., Bekele B.N., Aldape K.D. MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma. Neuro Oncol. 2010, 12:116-121.
    • (2010) Neuro Oncol. , vol.12 , pp. 116-121
    • Rivera, A.L.1    Pelloski, C.E.2    Gilbert, M.R.3    Colman, H.4    De La Cruz, C.5    Sulman, E.P.6    Bekele, B.N.7    Aldape, K.D.8
  • 201
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • Robertson K.D. DNA methylation and human disease. Nat. Rev. Genet. 2005, 6:597-610.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 202
    • 33750600178 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • Roldo C., Missiaglia E., Hagan J.P., Falconi M., Capelli P., Bersani S., Calin G.A., Volinia S., Liu C.G., Scarpa A., et al. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J. Clin. Oncol. 2006, 24:4677-4684.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 4677-4684
    • Roldo, C.1    Missiaglia, E.2    Hagan, J.P.3    Falconi, M.4    Capelli, P.5    Bersani, S.6    Calin, G.A.7    Volinia, S.8    Liu, C.G.9    Scarpa, A.10
  • 203
    • 27944504788 scopus 로고    scopus 로고
    • Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia
    • Roman-Gomez J., Jimenez-Velasco A., Agirre X., Cervantes F., Sanchez J., Garate L., Barrios M., Castillejo J.A., Navarro G., Colomer D., et al. Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia. Oncogene 2005, 24:7213-7223.
    • (2005) Oncogene , vol.24 , pp. 7213-7223
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Agirre, X.3    Cervantes, F.4    Sanchez, J.5    Garate, L.6    Barrios, M.7    Castillejo, J.A.8    Navarro, G.9    Colomer, D.10
  • 205
    • 28544442448 scopus 로고    scopus 로고
    • Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy
    • Rosenbaum E., Hoque M.O., Cohen Y., Zahurak M., Eisenberger M.A., Epstein J.I., Partin A.W., Sidransky D. Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy. Clin. Cancer Res. 2005, 11:8321-8325.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 8321-8325
    • Rosenbaum, E.1    Hoque, M.O.2    Cohen, Y.3    Zahurak, M.4    Eisenberger, M.A.5    Epstein, J.I.6    Partin, A.W.7    Sidransky, D.8
  • 206
    • 26944448622 scopus 로고    scopus 로고
    • Do septins have a role in cancer?
    • Russell S.E., Hall P.A. Do septins have a role in cancer?. Br. J. Cancer 2005, 93:499-503.
    • (2005) Br. J. Cancer , vol.93 , pp. 499-503
    • Russell, S.E.1    Hall, P.A.2
  • 209
    • 0037598752 scopus 로고    scopus 로고
    • Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas
    • Saito Y., Kanai Y., Nakagawa T., Sakamoto M., Saito H., Ishii H., Hirohashi S. Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas. Int. J. Cancer 2003, 105:527-532.
    • (2003) Int. J. Cancer , vol.105 , pp. 527-532
    • Saito, Y.1    Kanai, Y.2    Nakagawa, T.3    Sakamoto, M.4    Saito, H.5    Ishii, H.6    Hirohashi, S.7
  • 210
    • 77950983736 scopus 로고    scopus 로고
    • Long interspersed nuclear element 1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer
    • Saito K., Kawakami K., Matsumoto I., Oda M., Watanabe G., Minamoto T. Long interspersed nuclear element 1 hypomethylation is a marker of poor prognosis in stage IA non-small cell lung cancer. Clin. Cancer Res. 2010, 16:2418-2426.
    • (2010) Clin. Cancer Res. , vol.16 , pp. 2418-2426
    • Saito, K.1    Kawakami, K.2    Matsumoto, I.3    Oda, M.4    Watanabe, G.5    Minamoto, T.6
  • 211
    • 77953022034 scopus 로고    scopus 로고
    • Implication of microRNAs in drug resistance for designing novel cancer therapy
    • 10.1016/j.drup. 2010.02.001
    • Sarkar F.H., Li Y., Wang Z., Kong D., Ali S. Implication of microRNAs in drug resistance for designing novel cancer therapy. Drug Resist. Updat. 2010, 10.1016/j.drup. 2010.02.001.
    • (2010) Drug Resist. Updat.
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4    Ali, S.5
  • 216
    • 77951224561 scopus 로고    scopus 로고
    • MicroRNA-15b represents an independent prognostic parameter and is correlated with tumor cell proliferation and apoptosis in malignant melanoma
    • Satzger I., Mattern A., Kuettler U., Weinspach D., Voelker B., Kapp A., Gutzmer R. MicroRNA-15b represents an independent prognostic parameter and is correlated with tumor cell proliferation and apoptosis in malignant melanoma. Int. J. Cancer 2010, 126:2553-2562.
    • (2010) Int. J. Cancer , vol.126 , pp. 2553-2562
    • Satzger, I.1    Mattern, A.2    Kuettler, U.3    Weinspach, D.4    Voelker, B.5    Kapp, A.6    Gutzmer, R.7
  • 219
    • 21244467485 scopus 로고    scopus 로고
    • Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk
    • Schulmann K., Sterian A., Berki A., Yin J., Sato F., Xu Y., Olaru A., Wang S., Mori Y., Deacu E., et al. Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk. Oncogene 2005, 24:4138-4148.
    • (2005) Oncogene , vol.24 , pp. 4138-4148
    • Schulmann, K.1    Sterian, A.2    Berki, A.3    Yin, J.4    Sato, F.5    Xu, Y.6    Olaru, A.7    Wang, S.8    Mori, Y.9    Deacu, E.10
  • 220
    • 21344444056 scopus 로고    scopus 로고
    • Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumors
    • Scott M., Hyland P.L., McGregor G., Hillan K.J., Russell S.E.H., Hall P.A. Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumors. Oncogene 2005, 24:4688-4700.
    • (2005) Oncogene , vol.24 , pp. 4688-4700
    • Scott, M.1    Hyland, P.L.2    McGregor, G.3    Hillan, K.J.4    Russell, S.E.H.5    Hall, P.A.6
  • 221
    • 0033626213 scopus 로고    scopus 로고
    • Increase in the frequency of p16INK4 gene inactivation by hypermethylation in lung cancer during the process of metastasis and its relation to the status of p53
    • Seike M., Gemma A., Hosoya Y., Hemmi S., Taniguchi Y., Fukuda Y., Yamanaka N., Kudoh S. Increase in the frequency of p16INK4 gene inactivation by hypermethylation in lung cancer during the process of metastasis and its relation to the status of p53. Clin. Cancer Res. 2000, 6:4307-4313.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4307-4313
    • Seike, M.1    Gemma, A.2    Hosoya, Y.3    Hemmi, S.4    Taniguchi, Y.5    Fukuda, Y.6    Yamanaka, N.7    Kudoh, S.8
  • 222
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • Seligson D.B., Horvath S., Shi T., Yu H., Tze S., Grunstein M., Kurdistani S.K. Global histone modification patterns predict risk of prostate cancer recurrence. Nature 2005, 435:1262-1266.
    • (2005) Nature , vol.435 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3    Yu, H.4    Tze, S.5    Grunstein, M.6    Kurdistani, S.K.7
  • 224
    • 35448952469 scopus 로고    scopus 로고
    • Expression of anion exchanger 1 sequestrates p16 in the cytoplasm in gastric and colonic adenocarcinoma
    • Shen W.W., Wu J., Cai L., Liu B.Y., Gao Y., Chen G.Q., Fu G.H. Expression of anion exchanger 1 sequestrates p16 in the cytoplasm in gastric and colonic adenocarcinoma. Neoplasia 2007, 9:812-819.
    • (2007) Neoplasia , vol.9 , pp. 812-819
    • Shen, W.W.1    Wu, J.2    Cai, L.3    Liu, B.Y.4    Gao, Y.5    Chen, G.Q.6    Fu, G.H.7
  • 226
    • 46949104584 scopus 로고    scopus 로고
    • Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation
    • Shibata S., Yokota T., Wutz A. Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation. EMBO J. 2008, 27:1816-1826.
    • (2008) EMBO J. , vol.27 , pp. 1816-1826
    • Shibata, S.1    Yokota, T.2    Wutz, A.3
  • 227
    • 0342748644 scopus 로고    scopus 로고
    • Correlation of p16 hypermethylation with p16 protein loss in sporadic gastric carcinomas
    • Shim Y.H., Kang G.H., Ro J.Y. Correlation of p16 hypermethylation with p16 protein loss in sporadic gastric carcinomas. Lab. Invest. 2000, 80:689-695.
    • (2000) Lab. Invest. , vol.80 , pp. 689-695
    • Shim, Y.H.1    Kang, G.H.2    Ro, J.Y.3
  • 232
    • 39049128249 scopus 로고    scopus 로고
    • Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer
    • Slaby O., Svoboda M., Fabian P., Smerdova T., Knoflickova D., Bednarikova M., Nenutil R., Vyzula R. Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology 2007, 7:397-402.
    • (2007) Oncology , vol.7 , pp. 397-402
    • Slaby, O.1    Svoboda, M.2    Fabian, P.3    Smerdova, T.4    Knoflickova, D.5    Bednarikova, M.6    Nenutil, R.7    Vyzula, R.8
  • 235
    • 68949145132 scopus 로고    scopus 로고
    • Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: The alternative dosing for outpatient treatment (ADOPT) trial
    • Steensma D.P., Baer M.R., Slack J.L., Buckstein R., Godley L.A., Garcia-Manero G., Albitar M., Larsen J.S., Arora S., Cullen M.T., et al. Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: The alternative dosing for outpatient treatment (ADOPT) trial. J. Clin. Oncol. 2010, 27:3842-3848.
    • (2010) J. Clin. Oncol. , vol.27 , pp. 3842-3848
    • Steensma, D.P.1    Baer, M.R.2    Slack, J.L.3    Buckstein, R.4    Godley, L.A.5    Garcia-Manero, G.6    Albitar, M.7    Larsen, J.S.8    Arora, S.9    Cullen, M.T.10
  • 237
    • 0033535612 scopus 로고    scopus 로고
    • A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer
    • Strathdee G., MacKean M.J., Illand M., Brown R. A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer. Oncogene 1999, 18:2335-2341.
    • (1999) Oncogene , vol.18 , pp. 2335-2341
    • Strathdee, G.1    MacKean, M.J.2    Illand, M.3    Brown, R.4
  • 239
    • 4143063626 scopus 로고    scopus 로고
    • Methylation of p16 CpG islands associated with malignant transformation of gastric dysplasia in a population-based study
    • Sun Y., Deng D., You W.C., Bai H., Zhang L., Zhou J., Shen L., Ma J.L., Xie Y.Q., Li J.Y. Methylation of p16 CpG islands associated with malignant transformation of gastric dysplasia in a population-based study. Clin. Cancer Res. 2004, 10:5087-5093.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 5087-5093
    • Sun, Y.1    Deng, D.2    You, W.C.3    Bai, H.4    Zhang, L.5    Zhou, J.6    Shen, L.7    Ma, J.L.8    Xie, Y.Q.9    Li, J.Y.10
  • 240
    • 2442424419 scopus 로고    scopus 로고
    • Germline epimutation of MLH1 in individuals with multiple cancers
    • Suter C.M., Martin D.I.K., Ward R.L. Germline epimutation of MLH1 in individuals with multiple cancers. Nat. Genet. 2004, 36:497-501.
    • (2004) Nat. Genet. , vol.36 , pp. 497-501
    • Suter, C.M.1    Martin, D.I.K.2    Ward, R.L.3
  • 241
    • 54849186900 scopus 로고    scopus 로고
    • Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer
    • Svoboda M., Izakovicova Holla L., Sefr R., Vrtkova I., Kocakova I., Tichy B., Dvorak J. Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer. Int. J. Oncol. 2008, 33:541-547.
    • (2008) Int. J. Oncol. , vol.33 , pp. 541-547
    • Svoboda, M.1    Izakovicova Holla, L.2    Sefr, R.3    Vrtkova, I.4    Kocakova, I.5    Tichy, B.6    Dvorak, J.7
  • 242
    • 70350048828 scopus 로고    scopus 로고
    • Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas
    • Swisher E.M., Gonzalez R.M., Taniguchi T., Garcia R.L., Walsh T., Goff B.A., Welcsh P. Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas. Mol. Cancer 2009, 8:48.
    • (2009) Mol. Cancer , vol.8 , pp. 48
    • Swisher, E.M.1    Gonzalez, R.M.2    Taniguchi, T.3    Garcia, R.L.4    Walsh, T.5    Goff, B.A.6    Welcsh, P.7
  • 245
    • 0037099615 scopus 로고    scopus 로고
    • The association of death-associated protein kinase hypermethylation with early recurrence in superficial bladder cancers
    • Tada Y., Wada M., Taguchi K., Mochida Y., Kinugawa N., Tsuneyoshi M., Naito S., Kuwano M. The association of death-associated protein kinase hypermethylation with early recurrence in superficial bladder cancers. Cancer Res. 2002, 62:4048-4053.
    • (2002) Cancer Res. , vol.62 , pp. 4048-4053
    • Tada, Y.1    Wada, M.2    Taguchi, K.3    Mochida, Y.4    Kinugawa, N.5    Tsuneyoshi, M.6    Naito, S.7    Kuwano, M.8
  • 246
    • 0035510088 scopus 로고    scopus 로고
    • Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer
    • Takai D., Gonzales F.A., Tsai Y.C., Thayer M.J., Jones P.A. Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer. Hum. Mol. Genet. 2001, 10:2619-2626.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2619-2626
    • Takai, D.1    Gonzales, F.A.2    Tsai, Y.C.3    Thayer, M.J.4    Jones, P.A.5
  • 251
    • 0034692447 scopus 로고    scopus 로고
    • Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage-I non-small-cell lung cancer
    • Tang X., Khuri F.R., Lee J.J., Kemp B.L., Liu D., Hong W.K., Mao L. Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage-I non-small-cell lung cancer. J. Natl. Cancer Inst. 2000, 92:1511-1516.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1511-1516
    • Tang, X.1    Khuri, F.R.2    Lee, J.J.3    Kemp, B.L.4    Liu, D.5    Hong, W.K.6    Mao, L.7
  • 253
    • 45449093192 scopus 로고    scopus 로고
    • MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
    • Taylor D.D., Gercel-Taylor C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol. Oncol. 2008, 110:13-21.
    • (2008) Gynecol. Oncol. , vol.110 , pp. 13-21
    • Taylor, D.D.1    Gercel-Taylor, C.2
  • 254
    • 0032419812 scopus 로고    scopus 로고
    • Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
    • Thorvaldsen J.L., Duran K.L., Bartolomei M.S. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev. 1998, 12:3693-3702.
    • (1998) Genes Dev. , vol.12 , pp. 3693-3702
    • Thorvaldsen, J.L.1    Duran, K.L.2    Bartolomei, M.S.3
  • 255
    • 0035134705 scopus 로고    scopus 로고
    • Methylation of the p15(INK4B) gene in myelodysplastic syndrome: It can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation
    • Tien H.F., Tang J.H., Tsay W., Liu M.C., Lee F.Y., Wang C.H., Chen Y.C., Shen M.C. Methylation of the p15(INK4B) gene in myelodysplastic syndrome: It can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation. Br. J. Haematol. 2001, 112:148-154.
    • (2001) Br. J. Haematol. , vol.112 , pp. 148-154
    • Tien, H.F.1    Tang, J.H.2    Tsay, W.3    Liu, M.C.4    Lee, F.Y.5    Wang, C.H.6    Chen, Y.C.7    Shen, M.C.8
  • 256
    • 8444238560 scopus 로고    scopus 로고
    • Clinicopathological significance of aberrant methylation of RARbeta2 at 3p24, RASSF1A at 3p21.3, and FHIT at 3p14.2 in patients with non-small cell lung cancer
    • Tomizawa Y., Iijima H., Nomoto T., Iwasaki Y., Otani Y., Tsuchiya S., Saito R., Dobashi K., Nakajima T., Mori M. Clinicopathological significance of aberrant methylation of RARbeta2 at 3p24, RASSF1A at 3p21.3, and FHIT at 3p14.2 in patients with non-small cell lung cancer. Lung Cancer 2004, 46:305-312.
    • (2004) Lung Cancer , vol.46 , pp. 305-312
    • Tomizawa, Y.1    Iijima, H.2    Nomoto, T.3    Iwasaki, Y.4    Otani, Y.5    Tsuchiya, S.6    Saito, R.7    Dobashi, K.8    Nakajima, T.9    Mori, M.10
  • 260
    • 0038581890 scopus 로고    scopus 로고
    • Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease
    • Tufarelli C., Stanley J.A., Garrick D., Sharpe J.A., Ayyub H., Wood W.G., Higgs D.R. Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease. Nat. Genet. 2003, 34:157-165.
    • (2003) Nat. Genet. , vol.34 , pp. 157-165
    • Tufarelli, C.1    Stanley, J.A.2    Garrick, D.3    Sharpe, J.A.4    Ayyub, H.5    Wood, W.G.6    Higgs, D.R.7
  • 261
    • 59149096527 scopus 로고    scopus 로고
    • Prognostic significance of global histone modifications in resected squamous cell carcinoma of the esophagus
    • Tzao C., Tung H.J., Jin J.S., Sun G.H., Hsu H.S., Chen B.H., Yu C.P., Lee S.C. Prognostic significance of global histone modifications in resected squamous cell carcinoma of the esophagus. Mod. Pathol. 2009, 22:252-260.
    • (2009) Mod. Pathol. , vol.22 , pp. 252-260
    • Tzao, C.1    Tung, H.J.2    Jin, J.S.3    Sun, G.H.4    Hsu, H.S.5    Chen, B.H.6    Yu, C.P.7    Lee, S.C.8
  • 263
    • 9344244741 scopus 로고    scopus 로고
    • Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis
    • Umetani N., Takeuchi H., Fujimoto A., Shinozaki M., Bilchik A.J., Hoon D.S. Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis. Clin. Cancer Res. 2004, 10:7475-7483.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 7475-7483
    • Umetani, N.1    Takeuchi, H.2    Fujimoto, A.3    Shinozaki, M.4    Bilchik, A.J.5    Hoon, D.S.6
  • 264
    • 0037081085 scopus 로고    scopus 로고
    • Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer
    • Usadel H., Brabender J., Danenberg K.D., Jerónimo C., Harden S., Engles J., Danenberg P.V., Yang S., Sidransky D. Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer. Cancer Res. 2002, 62:371-375.
    • (2002) Cancer Res. , vol.62 , pp. 371-375
    • Usadel, H.1    Brabender, J.2    Danenberg, K.D.3    Jerónimo, C.4    Harden, S.5    Engles, J.6    Danenberg, P.V.7    Yang, S.8    Sidransky, D.9
  • 265
    • 14644396228 scopus 로고    scopus 로고
    • Detection and interpretation of altered methylation patterns in cancer cells
    • Ushijima T. Detection and interpretation of altered methylation patterns in cancer cells. Nat. Rev. Cancer 2005, 5:223-231.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 223-231
    • Ushijima, T.1
  • 266
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H., Ekström K., Bossios A., Sjöstrand M., Lee J.J., Lötvall J.O. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 2007, 9:654-659.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 654-659
    • Valadi, H.1    Ekström, K.2    Bossios, A.3    Sjöstrand, M.4    Lee, J.J.5    Lötvall, J.O.6
  • 269
    • 0034880739 scopus 로고    scopus 로고
    • Cell type-specific induction of O6-alkylguanine-DNA alkyltransferase mRNA expression in rat liver during regeneration, inflammation and preneoplasia
    • Vielhauer V., Sarafoff M., Gais P., Rabes H.M. Cell type-specific induction of O6-alkylguanine-DNA alkyltransferase mRNA expression in rat liver during regeneration, inflammation and preneoplasia. J. Cancer Res. Clin. Oncol. 2001, 127:591-602.
    • (2001) J. Cancer Res. Clin. Oncol. , vol.127 , pp. 591-602
    • Vielhauer, V.1    Sarafoff, M.2    Gais, P.3    Rabes, H.M.4
  • 271
    • 46349086833 scopus 로고    scopus 로고
    • Association between chromosomal instability and prognosis in colorectal cancer: A meta-analysis
    • Walther A., Houlston R., Tomlinson I. Association between chromosomal instability and prognosis in colorectal cancer: A meta-analysis. Gut 2008, 57:941-950.
    • (2008) Gut , vol.57 , pp. 941-950
    • Walther, A.1    Houlston, R.2    Tomlinson, I.3
  • 274
    • 34249294535 scopus 로고    scopus 로고
    • A change in promoter methylation of hMLH1 is a cause of acquired resistance to platinum-based chemotherapy in epithelial ovarian cancer
    • Watanabe Y., Ueda H., Etoh T., Koike E., Fujinami N., Mitsuhashi A., Hoshiai H. A change in promoter methylation of hMLH1 is a cause of acquired resistance to platinum-based chemotherapy in epithelial ovarian cancer. Anticancer Res. 2007, 27(3B):1449-1452.
    • (2007) Anticancer Res. , vol.27 , Issue.3 B , pp. 1449-1452
    • Watanabe, Y.1    Ueda, H.2    Etoh, T.3    Koike, E.4    Fujinami, N.5    Mitsuhashi, A.6    Hoshiai, H.7
  • 275
    • 0030874380 scopus 로고    scopus 로고
    • Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene
    • Watts G.S., Pieper R.O., Costello J.F., Peng Y.M., Dalton W.S., Futscher B.W. Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene. Mol. Cell. Biol. 1997, 17:5612-5619.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5612-5619
    • Watts, G.S.1    Pieper, R.O.2    Costello, J.F.3    Peng, Y.M.4    Dalton, W.S.5    Futscher, B.W.6
  • 276
    • 38549157208 scopus 로고    scopus 로고
    • Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: A retrospective analysis
    • Weichert W., Röske A., Gekeler V., Beckers T., Ebert M.P., Pross M., Dietel M., Denkert C., Röcken C. Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: A retrospective analysis. Lancet Oncol. 2008, 9:139-148.
    • (2008) Lancet Oncol. , vol.9 , pp. 139-148
    • Weichert, W.1    Röske, A.2    Gekeler, V.3    Beckers, T.4    Ebert, M.P.5    Pross, M.6    Dietel, M.7    Denkert, C.8    Röcken, C.9
  • 277
    • 38949086502 scopus 로고    scopus 로고
    • Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy
    • Weichert W., Röske A., Gekeler V., Beckers T., Stephan C., Jung K., Fritzsche F.R., Niesporek S., Denkert C., Dietel M., et al. Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy. Br. J. Cancer 2008, 98:604-610.
    • (2008) Br. J. Cancer , vol.98 , pp. 604-610
    • Weichert, W.1    Röske, A.2    Gekeler, V.3    Beckers, T.4    Stephan, C.5    Jung, K.6    Fritzsche, F.R.7    Niesporek, S.8    Denkert, C.9    Dietel, M.10
  • 280
    • 38449120703 scopus 로고    scopus 로고
    • CD44 and PTGS2 methylation are independent prognostic markers for biochemical recurrence among prostate cancer patients with clinically localized disease
    • Woodson K., O'Reilly K.J., Ward D.E., Walter J., Hanson J., Walk E.L., Tangrea J.A. CD44 and PTGS2 methylation are independent prognostic markers for biochemical recurrence among prostate cancer patients with clinically localized disease. Epigenetics 2006, 1:183-186.
    • (2006) Epigenetics , vol.1 , pp. 183-186
    • Woodson, K.1    O'Reilly, K.J.2    Ward, D.E.3    Walter, J.4    Hanson, J.5    Walk, E.L.6    Tangrea, J.A.7
  • 281
    • 0031945061 scopus 로고    scopus 로고
    • Overexpression of mutant p53 and c-erbB-2 proteins and mutations of the p15 and p16 genes in human gastric carcinoma: With respect to histological subtypes and stages
    • Wu M.S., Shun C.T., Sheu J.C., Wang H.P., Wang J.T., Lee W.J., Chen C.J., Wang T.H., Lin J.T. Overexpression of mutant p53 and c-erbB-2 proteins and mutations of the p15 and p16 genes in human gastric carcinoma: With respect to histological subtypes and stages. J. Gastroenterol. Hepatol. 1998, 13:305-310.
    • (1998) J. Gastroenterol. Hepatol. , vol.13 , pp. 305-310
    • Wu, M.S.1    Shun, C.T.2    Sheu, J.C.3    Wang, H.P.4    Wang, J.T.5    Lee, W.J.6    Chen, C.J.7    Wang, T.H.8    Lin, J.T.9
  • 282
    • 42049111429 scopus 로고    scopus 로고
    • Hypomethylated and hypermethylated profiles of H19DMR are associated with the aberrant imprinting of IGF2 and H19 in human hepatocellular carcinoma
    • Wu J., Qin Y., Li B., He W.Z., Sun Z.L. Hypomethylated and hypermethylated profiles of H19DMR are associated with the aberrant imprinting of IGF2 and H19 in human hepatocellular carcinoma. Genomics 2008, 91:443-450.
    • (2008) Genomics , vol.91 , pp. 443-450
    • Wu, J.1    Qin, Y.2    Li, B.3    He, W.Z.4    Sun, Z.L.5
  • 284
    • 77949437852 scopus 로고    scopus 로고
    • Methylation status of individual CpG sites within Alu elements in the human genome and Alu hypomethylation in gastric carcinomas
    • Xiang S., Liu Z., Zhang B., Zhou J., Zhu B.D., Ji J., Deng D. Methylation status of individual CpG sites within Alu elements in the human genome and Alu hypomethylation in gastric carcinomas. BMC Cancer 2010, 10:44.
    • (2010) BMC Cancer , vol.10 , pp. 44
    • Xiang, S.1    Liu, Z.2    Zhang, B.3    Zhou, J.4    Zhu, B.D.5    Ji, J.6    Deng, D.7
  • 285
    • 53749097323 scopus 로고    scopus 로고
    • Clinical significance of detection of tumor suppressor genes aberrant methylation in cervical carcinoma tissue
    • Xu J., Wang H.L., Lu G.C., Wang Z.J., Lin X., Zhou H.W. Clinical significance of detection of tumor suppressor genes aberrant methylation in cervical carcinoma tissue. Zhonghua Fu Chan Ke Za Zhi 2007, 42:394-397.
    • (2007) Zhonghua Fu Chan Ke Za Zhi , vol.42 , pp. 394-397
    • Xu, J.1    Wang, H.L.2    Lu, G.C.3    Wang, Z.J.4    Lin, X.5    Zhou, H.W.6
  • 286
    • 55549120234 scopus 로고    scopus 로고
    • MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
    • Yan L.X., Huang X.F., Shao Q., Huang M.Y., Deng L., Wu Q.L., Zeng Y.X., Shao J.Y. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA 2008, 14:2348-2360.
    • (2008) RNA , vol.14 , pp. 2348-2360
    • Yan, L.X.1    Huang, X.F.2    Shao, Q.3    Huang, M.Y.4    Deng, L.5    Wu, Q.L.6    Zeng, Y.X.7    Shao, J.Y.8
  • 288
    • 57749105325 scopus 로고    scopus 로고
    • MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer
    • Yang N., Kaur S., Volinia S., Greshock J., Lassus H., Hasegawa K., Liang S., Leminen A., Deng S., Smith L., et al. MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer. Cancer Res. 2008, 68:10307-10314.
    • (2008) Cancer Res. , vol.68 , pp. 10307-10314
    • Yang, N.1    Kaur, S.2    Volinia, S.3    Greshock, J.4    Lassus, H.5    Hasegawa, K.6    Liang, S.7    Leminen, A.8    Deng, S.9    Smith, L.10
  • 293
    • 55349130961 scopus 로고    scopus 로고
    • DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity
    • Yegnasubramanian S., Haffner M.C., Zhang Y., Gurel B., Cornish T.C., Wu Z., Irizarry R.A., Morgan J., Hicks J., DeWeese T.L., et al. DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity. Cancer Res. 2008, 68:8954-8967.
    • (2008) Cancer Res. , vol.68 , pp. 8954-8967
    • Yegnasubramanian, S.1    Haffner, M.C.2    Zhang, Y.3    Gurel, B.4    Cornish, T.C.5    Wu, Z.6    Irizarry, R.A.7    Morgan, J.8    Hicks, J.9    DeWeese, T.L.10
  • 295
    • 37549047612 scopus 로고    scopus 로고
    • A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer
    • Yu J., Zhu T., Wang Z., Zhang H., Qian Z., Xu H., Gao B., Wang W., Gu L., Meng J., et al. A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer. Clin. Cancer Res. 2007, 13:7296-7304.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 7296-7304
    • Yu, J.1    Zhu, T.2    Wang, Z.3    Zhang, H.4    Qian, Z.5    Xu, H.6    Gao, B.7    Wang, W.8    Gu, L.9    Meng, J.10
  • 299
    • 0028023861 scopus 로고
    • Deletions of chromosome 13q, mutations in Retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma
    • Zhang X., Xu H.J., Murakami Y., Sachse R., Yashima K., Hirohashi S., Hu S.X., Benedict W.F., Sekiya T. Deletions of chromosome 13q, mutations in Retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma. Cancer Res. 1994, 54:4177-4182.
    • (1994) Cancer Res. , vol.54 , pp. 4177-4182
    • Zhang, X.1    Xu, H.J.2    Murakami, Y.3    Sachse, R.4    Yashima, K.5    Hirohashi, S.6    Hu, S.X.7    Benedict, W.F.8    Sekiya, T.9
  • 301
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • Zhu S., Si M.L., Wu H., Mo Y.Y. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J. Biol. Chem. 2007, 282:14328-14336.
    • (2007) J. Biol. Chem. , vol.282 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4


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