-
1
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M. Epigenetics in cancer. N Engl J Med. 2008;358(11):1148-1159.
-
(2008)
N Engl J Med
, vol.358
, Issue.11
, pp. 1148-1159
-
-
Esteller, M.1
-
2
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell. 2007;128(4):683-692.
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
3
-
-
2342557977
-
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
-
Yang AS, Estecio MR, Doshi K, Kondo Y, Tajara EH, Issa JP. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res. 2004;32(3):e38.
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.3
-
-
Yang, A.S.1
Estecio, M.R.2
Doshi, K.3
Kondo, Y.4
Tajara, E.H.5
Issa, J.P.6
-
4
-
-
29244490041
-
Analysis of repetitive element DNA methylation by MethyLight
-
Weisenberger DJ, Campan M, Long TI, et al. Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res. 2005;33(21):6823-6836.
-
(2005)
Nucleic Acids Res
, vol.33
, Issue.21
, pp. 6823-6836
-
-
Weisenberger, D.J.1
Campan, M.2
Long, T.I.3
-
5
-
-
33744918070
-
DNA methylation changes after 5-aza-2′-deoxycytidine therapy in patients with leukemia
-
Yang AS, Doshi KD, Choi SW, et al. DNA methylation changes after 5-aza-2′-deoxycytidine therapy in patients with leukemia. Cancer Res. 2006;66(10):5495-5503.
-
(2006)
Cancer Res
, vol.66
, Issue.10
, pp. 5495-5503
-
-
Yang, A.S.1
Doshi, K.D.2
Choi, S.W.3
-
6
-
-
23744461983
-
Transposons reanimated in mice
-
Bestor TH. Transposons reanimated in mice. Cell. 2005;122(3):322-325.
-
(2005)
Cell
, vol.122
, Issue.3
, pp. 322-325
-
-
Bestor, T.H.1
-
7
-
-
0030867514
-
DNA demethylation and pericentromeric rearrangements of chromosome 1
-
Ji W, Hernandez R, Zhang XY, et al. DNA demethylation and pericentromeric rearrangements of chromosome 1. Mutat Res. 1997;379(1):33-41.
-
(1997)
Mutat Res
, vol.379
, Issue.1
, pp. 33-41
-
-
Ji, W.1
Hernandez, R.2
Zhang, X.Y.3
-
8
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet F, Hodgson JG, Eden A, et al. Induction of tumors in mice by genomic hypomethylation. Science. 2003;300(5618):489-492.
-
(2003)
Science
, vol.300
, Issue.5618
, pp. 489-492
-
-
Gaudet, F.1
Hodgson, J.G.2
Eden, A.3
-
9
-
-
26444473234
-
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis
-
Yamada Y, Jackson-Grusby L, Linhart H, et al. Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proc Natl Acad Sci USA. 2005;102(38):13580-13585.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.38
, pp. 13580-13585
-
-
Yamada, Y.1
Jackson-Grusby, L.2
Linhart, H.3
-
10
-
-
33749037187
-
Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers
-
Rodriguez J, Frigola J, Vendrell E, et al. Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers. Cancer Res. 2006;66(17):8462-9468.
-
(2006)
Cancer Res
, vol.66
, Issue.17
, pp. 8462-9468
-
-
Rodriguez, J.1
Frigola, J.2
Vendrell, E.3
-
11
-
-
33644825262
-
Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage
-
Suzuki K, Suzuki I, Leodolter A, et al. Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage. Cancer Cell. 2006;9(3):199-207.
-
(2006)
Cancer Cell
, vol.9
, Issue.3
, pp. 199-207
-
-
Suzuki, K.1
Suzuki, I.2
Leodolter, A.3
-
12
-
-
25444475765
-
Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells
-
Karpf AR, Matsui S. Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells. Cancer Res. 2005;65(19):8635-8639.
-
(2005)
Cancer Res
, vol.65
, Issue.19
, pp. 8635-8639
-
-
Karpf, A.R.1
Matsui, S.2
-
13
-
-
26644444345
-
Global loss of imprinting leads to widespread tumorigenesis in adult mice
-
Holm TM, Jackson-Grusby L, Brambrink T, Yamada Y, Rideout WM III, Jaenisch R. Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell. 2005;8(4):275-285.
-
(2005)
Cancer Cell
, vol.8
, Issue.4
, pp. 275-285
-
-
Holm, T.M.1
Jackson-Grusby, L.2
Brambrink, T.3
Yamada, Y.4
Rideout III, W.M.5
Jaenisch, R.6
-
14
-
-
9944233064
-
Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis
-
Chalitchagorn K, Shuangshoti S, Hourpai N, et al. Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis. Oncogene. 2004;23(54):8841-8846.
-
(2004)
Oncogene
, vol.23
, Issue.54
, pp. 8841-8846
-
-
Chalitchagorn, K.1
Shuangshoti, S.2
Hourpai, N.3
-
15
-
-
29344455676
-
The relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer
-
Matsuzaki K, Deng G, Tanaka H, Kakar S, Miura S, Kim YS. The relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer. Clin Cancer Res. 2005;11(24):8564-8569.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.24
, pp. 8564-8569
-
-
Matsuzaki, K.1
Deng, G.2
Tanaka, H.3
Kakar, S.4
Miura, S.5
Kim, Y.S.6
-
16
-
-
18344376930
-
The Nurses' Health Study: Lifestyle and health among women
-
Colditz GA, Hankinson SE. The Nurses' Health Study: lifestyle and health among women. Nat Rev Cancer. 2005;5(5):388-396.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.5
, pp. 388-396
-
-
Colditz, G.A.1
Hankinson, S.E.2
-
17
-
-
34249673868
-
Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
-
Chan AT, Ogino S, Fuchs CS. Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N Engl J Med. 2007;356(21):2131- 2142.
-
(2007)
N Engl J Med
, vol.356
, Issue.21
, pp. 2131-2142
-
-
Chan, A.T.1
Ogino, S.2
Fuchs, C.S.3
-
18
-
-
34547754622
-
A nested case control study of plasma 25-hydroxyvitamin D concentrations and risk of colorectal cancer
-
Wu K, Feskanich D, Fuchs CS, Willett WC, Hollis BW, Giovannucci EL. A nested case control study of plasma 25-hydroxyvitamin D concentrations and risk of colorectal cancer. J Natl Cancer Inst. 2007;99(14):1120-1129.
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.14
, pp. 1120-1129
-
-
Wu, K.1
Feskanich, D.2
Fuchs, C.S.3
Willett, W.C.4
Hollis, B.W.5
Giovannucci, E.L.6
-
19
-
-
41149123118
-
Family history and survival after colorectal cancer diagnosis
-
Bass AJ, Meyerhardt JA, Chan JA, Giovannucci EL, Fuchs CS. Family history and survival after colorectal cancer diagnosis. Cancer. 2008;112(6):1222-1229.
-
(2008)
Cancer
, vol.112
, Issue.6
, pp. 1222-1229
-
-
Bass, A.J.1
Meyerhardt, J.A.2
Chan, J.A.3
Giovannucci, E.L.4
Fuchs, C.S.5
-
20
-
-
23844497341
-
Sensitive sequencing method for KRAS mutation detection by Pyrosequencing
-
Ogino S, Kawasaki T, Brahmandam M, et al. Sensitive sequencing method for KRAS mutation detection by Pyrosequencing. J Mol Diagn. 2005;7(3):413-421.
-
(2005)
J Mol Diagn
, vol.7
, Issue.3
, pp. 413-421
-
-
Ogino, S.1
Kawasaki, T.2
Brahmandam, M.3
-
21
-
-
33749069927
-
CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: Possible associations with male sex and KRAS mutations
-
Ogino S, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS. CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations. J Mol Diagn. 2006;8(3):582-588.
-
(2006)
J Mol Diagn
, vol.8
, Issue.3
, pp. 582-588
-
-
Ogino, S.1
Kawasaki, T.2
Kirkner, G.J.3
Loda, M.4
Fuchs, C.S.5
-
22
-
-
34249789850
-
18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high
-
Ogino S, Kawasaki T, Kirkner GJ, Ohnishi M, Fuchs CS. 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high. BMC Cancer. 2007;7(1):72.
-
(2007)
BMC Cancer
, vol.7
, Issue.1
, pp. 72
-
-
Ogino, S.1
Kawasaki, T.2
Kirkner, G.J.3
Ohnishi, M.4
Fuchs, C.S.5
-
23
-
-
33845702458
-
Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP
-
Ogino S, kawasaki T, Kirkner GJ, Yamaji T, Loda M, Fuchs CS. Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP. Mod Pathol. 2007;20(1):15-22.
-
(2007)
Mod Pathol
, vol.20
, Issue.1
, pp. 15-22
-
-
Ogino, S.1
kawasaki, T.2
Kirkner, G.J.3
Yamaji, T.4
Loda, M.5
Fuchs, C.S.6
-
24
-
-
0034654669
-
MethyLight: A high-throughput assay to measure DNA methylation
-
Eads CA, Danenberg KD, Kawakami K, et al. MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res. 2000;28(8):E32.
-
(2000)
Nucleic Acids Res
, vol.28
, Issue.8
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
-
25
-
-
33744550591
-
Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis
-
Ogino S, kawasaki T, Brahmandam M, et al. Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. J Mol Diagn. 2006;8(2):209-217.
-
(2006)
J Mol Diagn
, vol.8
, Issue.2
, pp. 209-217
-
-
Ogino, S.1
kawasaki, T.2
Brahmandam, M.3
-
26
-
-
34247570795
-
Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample
-
Ogino S, Kawasaki T, Kirkner GJ, Kraft P, Loda M, Fuchs CS. Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample. J Mol Diagn. 2007;9(3):305-314.
-
(2007)
J Mol Diagn
, vol.9
, Issue.3
, pp. 305-314
-
-
Ogino, S.1
Kawasaki, T.2
Kirkner, G.J.3
Kraft, P.4
Loda, M.5
Fuchs, C.S.6
-
27
-
-
33745500432
-
CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies
-
Ogino S, Cantor M, Kawasaki T, et al. CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies. Gut. 2006;55(7):1000-1006.
-
(2006)
Gut
, vol.55
, Issue.7
, pp. 1000-1006
-
-
Ogino, S.1
Cantor, M.2
Kawasaki, T.3
-
28
-
-
33745541234
-
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
-
Weisenberger DJ, Siegmund KD, Campan M, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet. 2006;38(7):787-793.
-
(2006)
Nat Genet
, vol.38
, Issue.7
, pp. 787-793
-
-
Weisenberger, D.J.1
Siegmund, K.D.2
Campan, M.3
-
29
-
-
43049130760
-
LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG methylator phenotype in colorectal cancer
-
Ogino S, Kawasaki T, Nosho K, et al. LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG methylator phenotype in colorectal cancer. Int J Cancer. 2008;122(12):2767-2773.
-
(2008)
Int J Cancer
, vol.122
, Issue.12
, pp. 2767-2773
-
-
Ogino, S.1
Kawasaki, T.2
Nosho, K.3
-
30
-
-
36849059066
-
LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability
-
Estecio MR, Gharibyan V, Shen L, et al. LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. PLoS ONE. 2007;2(5):e399.
-
(2007)
PLoS ONE
, vol.2
, Issue.5
-
-
Estecio, M.R.1
Gharibyan, V.2
Shen, L.3
-
31
-
-
0024596532
-
Flexible regression models with cubic splines
-
Durrleman S, Simon R. Flexible regression models with cubic splines. Stat Med. 1989;8(5):551-561.
-
(1989)
Stat Med
, vol.8
, Issue.5
, pp. 551-561
-
-
Durrleman, S.1
Simon, R.2
-
32
-
-
35248889933
-
Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer
-
Mudduluru G, Medved F, Grobholz R, et al. Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer. Cancer. 2007;110(8):1697-1707.
-
(2007)
Cancer
, vol.110
, Issue.8
, pp. 1697-1707
-
-
Mudduluru, G.1
Medved, F.2
Grobholz, R.3
-
33
-
-
34047245618
-
Lymph node evaluation and survival after curative resection of colon cancer: Systematic review
-
Chang GJ, Rodriguez-Bigas MA, Skibber JM, Moyer VA. Lymph node evaluation and survival after curative resection of colon cancer: systematic review. J Natl Cancer Inst. 2007;99(6):433-441.
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.6
, pp. 433-441
-
-
Chang, G.J.1
Rodriguez-Bigas, M.A.2
Skibber, J.M.3
Moyer, V.A.4
-
34
-
-
36048995436
-
Prospective study of serum vitamin D and cancer mortality in the United States
-
Freedman DM, Looker AC, Chang SC , Graubard BI. Prospective study of serum vitamin D and cancer mortality in the United States. J Natl Cancer Inst. 2007;99(21):1594-1602.
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.21
, pp. 1594-1602
-
-
Freedman, D.M.1
Looker, A.C.2
Chang, S.C.3
Graubard, B.I.4
-
35
-
-
40549090918
-
Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations
-
Derks S, Postma C, Carvalho B, et al. Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations. Carcinogenesis. 2008;29(2):434-439.
-
(2008)
Carcinogenesis
, vol.29
, Issue.2
, pp. 434-439
-
-
Derks, S.1
Postma, C.2
Carvalho, B.3
-
36
-
-
33750218663
-
Population-based assessment of the surgical management of locally advanced colorectal cancer
-
Govindarajan A, Coburn NG, Kiss A, Rabeneck L, Smith AJ, Law CH. Population-based assessment of the surgical management of locally advanced colorectal cancer. J Natl Cancer Inst. 2006;98(20):1474-1481.
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.20
, pp. 1474-1481
-
-
Govindarajan, A.1
Coburn, N.G.2
Kiss, A.3
Rabeneck, L.4
Smith, A.J.5
Law, C.H.6
-
37
-
-
33751373088
-
Body mass index and outcomes in patients who receive adjuvant chemotherapy for colon cancer
-
Dignam JJ, Polite BN, Yothers G, et al. Body mass index and outcomes in patients who receive adjuvant chemotherapy for colon cancer. J Natl Cancer Inst. 2006;98(22):1647-1654.
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.22
, pp. 1647-1654
-
-
Dignam, J.J.1
Polite, B.N.2
Yothers, G.3
-
38
-
-
37149041833
-
Molecular classification and correlates in colorectal cancer
-
Ogino S, Goel A. Molecular classification and correlates in colorectal cancer. J Mol Diagn. 2008;10(1):13-27.
-
(2008)
J Mol Diagn
, vol.10
, Issue.1
, pp. 13-27
-
-
Ogino, S.1
Goel, A.2
-
39
-
-
10044239471
-
Global hypomethylation is common in prostate cancer cells: A quantitative predictor for clinical outcome?
-
Brothman AR, Swanson G, Maxwell TM, et al. Global hypomethylation is common in prostate cancer cells: a quantitative predictor for clinical outcome?. Cancer Genet Cytogenet. 2005;156(1):31-36.
-
(2005)
Cancer Genet Cytogenet
, vol.156
, Issue.1
, pp. 31-36
-
-
Brothman, A.R.1
Swanson, G.2
Maxwell, T.M.3
-
40
-
-
35648962315
-
Altered methionine metabolism and global DNA methylation in liver cancer: Relationship with genomic instability and prognosis
-
Calvisi DF, Simile MM, Ladu S, et al. Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis. Int J Cancer. 2007;121(11):2410-2420.
-
(2007)
Int J Cancer
, vol.121
, Issue.11
, pp. 2410-2420
-
-
Calvisi, D.F.1
Simile, M.M.2
Ladu, S.3
-
41
-
-
47649111322
-
LINE-1 hypomethylation level as a potential prognostic factor for epithelial ovarian cancer
-
Pattamadilok J, Huapai N, Rattanatanyong P, et al. LINE-1 hypomethylation level as a potential prognostic factor for epithelial ovarian cancer. Int J Gynecol Cancer. 2008;18(4):711-717.
-
(2008)
Int J Gynecol Cancer
, vol.18
, Issue.4
, pp. 711-717
-
-
Pattamadilok, J.1
Huapai, N.2
Rattanatanyong, P.3
-
42
-
-
27944504788
-
Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia
-
Roman-Gomez J, Jimenez-Velasco A, Agirre X, et al. Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia. Oncogene. 2005;24(48):7213-7223.
-
(2005)
Oncogene
, vol.24
, Issue.48
, pp. 7213-7223
-
-
Roman-Gomez, J.1
Jimenez-Velasco, A.2
Agirre, X.3
-
43
-
-
12744271900
-
Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer
-
Frigola J, Sole X, Paz MF, et al. Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer. Hum Mol Genet. 2005;14(2):319-326.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.2
, pp. 319-326
-
-
Frigola, J.1
Sole, X.2
Paz, M.F.3
-
44
-
-
38449086370
-
Induction of DNA hypomethylation by tumor hypoxia
-
Shahrzad S, Bertrand K, Minhas K, Coomber BL. Induction of DNA hypomethylation by tumor hypoxia. Epigenetics. 2007;2(2):119-125.
-
(2007)
Epigenetics
, vol.2
, Issue.2
, pp. 119-125
-
-
Shahrzad, S.1
Bertrand, K.2
Minhas, K.3
Coomber, B.L.4
-
45
-
-
35548937284
-
Oxidative stress and antioxidant defenses in goldfish liver in response to short-term exposure to arsenite
-
Bagnyukova TV, Luzhna LI, Pogribny IP, Lushchak VI. Oxidative stress and antioxidant defenses in goldfish liver in response to short-term exposure to arsenite. Environ Mol Mutagen. 2007;48(8):658-665.
-
(2007)
Environ Mol Mutagen
, vol.48
, Issue.8
, pp. 658-665
-
-
Bagnyukova, T.V.1
Luzhna, L.I.2
Pogribny, I.P.3
Lushchak, V.I.4
-
46
-
-
11144224065
-
Cyclooxygenase-2 expression: A significant prognostic indicator for patients with colorectal cancer
-
Soumaoro LT, Uetake H, Higuchi T, Takagi Y, Enomoto M, Sugihara K. Cyclooxygenase-2 expression: a significant prognostic indicator for patients with colorectal cancer. Clin Cancer Res. 2004;10(24):8465-8471.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.24
, pp. 8465-8471
-
-
Soumaoro, L.T.1
Uetake, H.2
Higuchi, T.3
Takagi, Y.4
Enomoto, M.5
Sugihara, K.6
|