Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer

British Journal of Cancer

Volumn 86, Issue 4, 2002, Pages 574-579

  Deng, G ^a   Peng, E ^a   Gum, J ^a   Terdiman, J ^a   Sleisenger, M ^a   Kim, Y S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Colorectal cancer; DNA methylation; hMLH1; Loss of heterozygosity

Indexed keywords

GENE PRODUCT; PROTEIN MLH1; PROTEIN MLH2; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; FAMILIAL CANCER; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; GENE SILENCING; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; METHYLATION; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; PROMOTER REGION; TUMOR CELL LINE;

ALLELES; CARRIER PROTEINS; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; DNA PRIMERS; DNA, NEOPLASM; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; IMMUNOENZYME TECHNIQUES; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0037065954     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600148     Document Type: Article

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