Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer

Human Molecular Genetics

Volumn 10, Issue 23, 2001, Pages 2619-2626

  Takai, Daiya ^a   Gonzales, Felicidad A ^a   Tsai, Yvonne C ^a   Thayer, Mathew J ^b   Jones, Peter A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; 5 METHYLCYTOSINE; BINDING PROTEIN; DNA; SOMATOMEDIN B;

ALLELE; ANIMAL CELL; ARTICLE; BINDING SITE; BLADDER CANCER; CELL CLONING; CHROMOSOME 11; CHROMOSOME 11P; COLON CANCER; CONTROLLED STUDY; DNA METHYLATION; EMBRYONAL TISSUE; FETUS; GENE CONTROL; GENE LOCUS; GENE MAPPING; GENOME IMPRINTING; HUMAN; HUMAN CELL; HUMAN TISSUE; HYBRID CELL; MOUSE; NEPHROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; URETER;

EID: 0035510088     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/10.23.2619     Document Type: Article

References (29)

1. Imprinting of a genomic domain of 11p15 and loss of imprinting in cancer: An introduction
2. The sins of the fathers and mothers: Genomic imprinting in mammalian development
3. Chromatin conformation of the H19 epigenetic mark
4. Epigenetic mechanisms underlying the imprinting of the mouse H19 gene
5. Parental-origin-specific epigenetic modification of the mouse H1 gene
6. Mouse/human sequence divergence in a region with a paternal-specific methylation imprint at the human H19 locus
7. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
8. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
9. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
10. The 5′ flank of mouse H19 in an unusual chromatin conformation unidirectionally blocks enhancer-promoter communication
11. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
12. High sensitivity mapping of methylated cytosines
13. Methylation sequencing analysis refines the region of H19 epimutation in Wilms tumor
14. Symmetric and asymmetric DNA methylation in the human IGF2-H19 imprinted region
15. Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer
16. Cellular differentiation, cytidine analogs and DNA methylation
17. Developmentally imprinted genes as markers for bladder tumor progression
18. The imprinted H19 gene is a marker of early recurrence in human bladder carcinoma
19. Frequent loss of imprinting of the H19 gene is often associated with its overexpression in human lung cancers
20. Molecular basis of base substitution hotspots in Escherichia coli
21. The sequence of the human genome
22. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
23. Isolation of microcell hybrid clones containing retroviral vector insertions into specific human chromosomes
24. Activation and repression of myogenesis in somatic cell hybrids: Evidence for trans-negative regulation of MyoD in primary fibroblasts
25. Preparation and analysis of eukaryotic genomic DNA
26. Extraction, purification and analysis of mRNA from eukaryotic cells
27. Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides
28. Cytosine methylation: Quantitation by automated genomic sequencing and GENESCAN analysis
29. Activation of an imprinted Igf2 gene in mouse somatic-cell cultures