-
1
-
-
0029665447
-
17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells
-
Altucci L., Addeo R., Cicatiello L., Dauvois S., Parker M.G., Truss M., Beato M., Sica V., Bresciani F., and Weisz A. 17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells. Oncogene 12 (1996) 2315-2324
-
(1996)
Oncogene
, vol.12
, pp. 2315-2324
-
-
Altucci, L.1
Addeo, R.2
Cicatiello, L.3
Dauvois, S.4
Parker, M.G.5
Truss, M.6
Beato, M.7
Sica, V.8
Bresciani, F.9
Weisz, A.10
-
3
-
-
0142181118
-
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses
-
The ATAC Trialists' Group
-
Baum M., Buzdar A., Cuzick J., Forbes J., Houghton J., Howell A., Sahmoud T., and The ATAC Trialists' Group. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses. Cancer 98 (2003) 1802-1810
-
(2003)
Cancer
, vol.98
, pp. 1802-1810
-
-
Baum, M.1
Buzdar, A.2
Cuzick, J.3
Forbes, J.4
Houghton, J.5
Howell, A.6
Sahmoud, T.7
-
4
-
-
0034238115
-
Down-regulation of p21WAF1/CIP1 or p27Kip1 abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells
-
Cariou S., Donovan J.C., Flanagan W.M., Milic A., Bhattacharya N., and Slingerland J.M. Down-regulation of p21WAF1/CIP1 or p27Kip1 abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells. Proc. Natl. Acad. Sci. USA 97 (2000) 9042-9046
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9042-9046
-
-
Cariou, S.1
Donovan, J.C.2
Flanagan, W.M.3
Milic, A.4
Bhattacharya, N.5
Slingerland, J.M.6
-
5
-
-
0037392444
-
Issues and progress with protein kinase inhibitors for cancer treatment
-
Dancey J., and Sausville E.A. Issues and progress with protein kinase inhibitors for cancer treatment. Nat. Rev. Drug Discov. 2 (2003) 296-313
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 296-313
-
-
Dancey, J.1
Sausville, E.A.2
-
6
-
-
0032537396
-
Tamoxifen for early breast cancer: An overview of the randomised trials
-
Early Breast Cancer Trialists' Collaborative Group
-
Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: An overview of the randomised trials. Lancet 351 (1998) 1451-1467
-
(1998)
Lancet
, vol.351
, pp. 1451-1467
-
-
-
7
-
-
33749023011
-
Minimizing the risk of reporting false positives in large-scale RNAi screens
-
Echeverri C.J., Beachy P.A., Baum B., Boutros M., Buchholz F., Chanda S.K., Downward J., Ellenberg J., Fraser A.G., Hacohen N., et al. Minimizing the risk of reporting false positives in large-scale RNAi screens. Nat. Methods 3 (2006) 777-779
-
(2006)
Nat. Methods
, vol.3
, pp. 777-779
-
-
Echeverri, C.J.1
Beachy, P.A.2
Baum, B.3
Boutros, M.4
Buchholz, F.5
Chanda, S.K.6
Downward, J.7
Ellenberg, J.8
Fraser, A.G.9
Hacohen, N.10
-
8
-
-
0030757687
-
Constitutive Raf-1 kinase activity in breast cancer cells induces both estrogen-independent growth and apoptosis
-
El-Ashry D., Miller D.L., Kharbanda S., Lippman M.E., and Kern F.G. Constitutive Raf-1 kinase activity in breast cancer cells induces both estrogen-independent growth and apoptosis. Oncogene 15 (1997) 423-435
-
(1997)
Oncogene
, vol.15
, pp. 423-435
-
-
El-Ashry, D.1
Miller, D.L.2
Kharbanda, S.3
Lippman, M.E.4
Kern, F.G.5
-
9
-
-
0035919923
-
Phosphorylation of ERK1/2 mitogen-activated protein kinase is associated with poor response to anti-hormonal therapy and decreased patient survival in clinical breast cancer
-
Gee J.M., Robertson J.F., Ellis I.O., and Nicholson R.I. Phosphorylation of ERK1/2 mitogen-activated protein kinase is associated with poor response to anti-hormonal therapy and decreased patient survival in clinical breast cancer. Int. J. Cancer 95 (2001) 247-254
-
(2001)
Int. J. Cancer
, vol.95
, pp. 247-254
-
-
Gee, J.M.1
Robertson, J.F.2
Ellis, I.O.3
Nicholson, R.I.4
-
11
-
-
33745614074
-
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing
-
Jackson A.L., Burchard J., Leake D., Reynolds A., Schelter J., Guo J., Johnson J.M., Lim L., Karpilow J., Nichols K., et al. Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing. RNA 12 (2006) 1197-1205
-
(2006)
RNA
, vol.12
, pp. 1197-1205
-
-
Jackson, A.L.1
Burchard, J.2
Leake, D.3
Reynolds, A.4
Schelter, J.5
Guo, J.6
Johnson, J.M.7
Lim, L.8
Karpilow, J.9
Nichols, K.10
-
12
-
-
0021771164
-
Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7
-
Jakowlew S.B., Breathnach R., Jeltsch J.M., Masiakowski P., and Chambon P. Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7. Nucleic Acids Res. 12 (1984) 2861-2878
-
(1984)
Nucleic Acids Res.
, vol.12
, pp. 2861-2878
-
-
Jakowlew, S.B.1
Breathnach, R.2
Jeltsch, J.M.3
Masiakowski, P.4
Chambon, P.5
-
13
-
-
20044377912
-
Molecular classification of tamoxifen-resistant breast carcinomas by gene expression profiling
-
Jansen M.P., Foekens J.A., van Staveren I.L., Dirkzwager-Kiel M.M., Ritstier K., Look M.P., Meijer-van Gelder M.E., Sieuwerts A.M., Portengen H., Dorssers L.C., et al. Molecular classification of tamoxifen-resistant breast carcinomas by gene expression profiling. J. Clin. Oncol. 23 (2005) 732-740
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 732-740
-
-
Jansen, M.P.1
Foekens, J.A.2
van Staveren, I.L.3
Dirkzwager-Kiel, M.M.4
Ritstier, K.5
Look, M.P.6
Meijer-van Gelder, M.E.7
Sieuwerts, A.M.8
Portengen, H.9
Dorssers, L.C.10
-
14
-
-
0036778135
-
A new estrogen receptor antagonist-An overview of available data
-
Jones S.E. A new estrogen receptor antagonist-An overview of available data. Breast Cancer Res. Treat. 75 (2002) S19-S21
-
(2002)
Breast Cancer Res. Treat.
, vol.75
-
-
Jones, S.E.1
-
15
-
-
0029436096
-
Third annual William L. McGuire Memorial Lecture. "Studies on the estrogen receptor in breast cancer"-20 years as a target for the treatment and prevention of cancer
-
Jordan V.C. Third annual William L. McGuire Memorial Lecture. "Studies on the estrogen receptor in breast cancer"-20 years as a target for the treatment and prevention of cancer. Breast Cancer Res. Treat. 36 (1995) 267-285
-
(1995)
Breast Cancer Res. Treat.
, vol.36
, pp. 267-285
-
-
Jordan, V.C.1
-
16
-
-
0035810047
-
Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity
-
Kasten M., and Giordano A. Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity. Oncogene 20 (2001) 1832-1838
-
(2001)
Oncogene
, vol.20
, pp. 1832-1838
-
-
Kasten, M.1
Giordano, A.2
-
17
-
-
0032771839
-
Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptor-positive breast cancer
-
Kenny F.S., Hui R., Musgrove E.A., Gee J.M., Blamey R.W., Nicholson R.I., Sutherland R.L., and Robertson J.F. Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptor-positive breast cancer. Clin. Cancer Res. 5 (1999) 2069-2076
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2069-2076
-
-
Kenny, F.S.1
Hui, R.2
Musgrove, E.A.3
Gee, J.M.4
Blamey, R.W.5
Nicholson, R.I.6
Sutherland, R.L.7
Robertson, J.F.8
-
18
-
-
0029786329
-
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
-
Lavoie J.N., L'Allemain G., Brunet A., Muller R., and Pouyssegur J. Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J. Biol. Chem. 271 (1996) 20608-20616
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20608-20616
-
-
Lavoie, J.N.1
L'Allemain, G.2
Brunet, A.3
Muller, R.4
Pouyssegur, J.5
-
19
-
-
34247145491
-
Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade
-
Loi S., Haibe-Kains B., Desmedt C., Lallemand F., Tutt A.M., Gillet C., Ellis P., Harris A., Bergh J., Foekens J.A., et al. Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade. J. Clin. Oncol. 25 (2007) 1239-1246
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 1239-1246
-
-
Loi, S.1
Haibe-Kains, B.2
Desmedt, C.3
Lallemand, F.4
Tutt, A.M.5
Gillet, C.6
Ellis, P.7
Harris, A.8
Bergh, J.9
Foekens, J.A.10
-
20
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
Mangelsdorf D.J., Thummel C., Beato M., Herrlich P., Schutz G., Umesono K., Blumberg B., Kastner P., Mark M., Chambon P., and Evans R.M. The nuclear receptor superfamily: The second decade. Cell 83 (1995) 835-839
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schutz, G.5
Umesono, K.6
Blumberg, B.7
Kastner, P.8
Mark, M.9
Chambon, P.10
Evans, R.M.11
-
22
-
-
16844375445
-
Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer
-
Myers E., Hill A.D., Kelly G., McDermott E.W., O'Higgins N.J., Buggy Y., and Young L.S. Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer. Clin. Cancer Res. 11 (2005) 2111-2122
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 2111-2122
-
-
Myers, E.1
Hill, A.D.2
Kelly, G.3
McDermott, E.W.4
O'Higgins, N.J.5
Buggy, Y.6
Young, L.S.7
-
23
-
-
0034899503
-
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells
-
Oh A.S., Lorant L.A., Holloway J.N., Miller D.L., Kern F.G., and El-Ashry D. Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells. Mol. Endocrinol. 15 (2001) 1344-1359
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 1344-1359
-
-
Oh, A.S.1
Lorant, L.A.2
Holloway, J.N.3
Miller, D.L.4
Kern, F.G.5
El-Ashry, D.6
-
24
-
-
18244391514
-
Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients
-
the Southeast Sweden Breast Cancer Group
-
Pérez-Tenorio G., Stål O., and the Southeast Sweden Breast Cancer Group. Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients. Br. J. Cancer 86 (2002) 540-545
-
(2002)
Br. J. Cancer
, vol.86
, pp. 540-545
-
-
Pérez-Tenorio, G.1
Stål, O.2
-
25
-
-
23744443778
-
Adaptive hypersensitivity to estrogen: Mechanisms and clinical relevance to aromatase inhibitor therapy in breast cancer treatment
-
Santen R.J., Song R.X., Zhang Z., Kumar R., Jeng M.H., Masamura S., Lawrence Jr. J., MacMahon L.P., Yue W., and Berstein L. Adaptive hypersensitivity to estrogen: Mechanisms and clinical relevance to aromatase inhibitor therapy in breast cancer treatment. J. Steroid Biochem. Mol. Biol. 95 (2005) 155-165
-
(2005)
J. Steroid Biochem. Mol. Biol.
, vol.95
, pp. 155-165
-
-
Santen, R.J.1
Song, R.X.2
Zhang, Z.3
Kumar, R.4
Jeng, M.H.5
Masamura, S.6
Lawrence Jr., J.7
MacMahon, L.P.8
Yue, W.9
Berstein, L.10
-
26
-
-
0029849620
-
Cancer cell cycles
-
Sherr C.J. Cancer cell cycles. Science 274 (1996) 1672-1677
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
27
-
-
2942652871
-
Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer
-
Shou J., Massarweh S., Osborne C.K., Wakeling A.E., Ali S., Weiss H., and Schiff R. Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer. J. Natl. Cancer Inst. 96 (2004) 926-935
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 926-935
-
-
Shou, J.1
Massarweh, S.2
Osborne, C.K.3
Wakeling, A.E.4
Ali, S.5
Weiss, H.6
Schiff, R.7
-
28
-
-
34547105055
-
Epigenetic inactivation implies independent tumour suppressor functions for IGFBP-rP1 and the related IGFBPL1 in breast cancer
-
Smith P., Nicholson L.J., Syed N., Payne A., Hiller L., Garrone O., Occelli M., Gasco M., and Crook T. Epigenetic inactivation implies independent tumour suppressor functions for IGFBP-rP1 and the related IGFBPL1 in breast cancer. Clin. Cancer Res. 15 (2007) 4061-4068
-
(2007)
Clin. Cancer Res.
, vol.15
, pp. 4061-4068
-
-
Smith, P.1
Nicholson, L.J.2
Syed, N.3
Payne, A.4
Hiller, L.5
Garrone, O.6
Occelli, M.7
Gasco, M.8
Crook, T.9
-
29
-
-
21744453318
-
ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis
-
Svensson S., Jirström K., Rydén L., Roos G., Emdin S., Ostrowski M.C., and Landberg G. ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis. Oncogene 24 (2005) 4370-4379
-
(2005)
Oncogene
, vol.24
, pp. 4370-4379
-
-
Svensson, S.1
Jirström, K.2
Rydén, L.3
Roos, G.4
Emdin, S.5
Ostrowski, M.C.6
Landberg, G.7
-
30
-
-
34249828179
-
Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs
-
Swanton C., Marani M., Pardo O., Warne P.H., Kelly G., Sahai E., Elustondo F., Chang J., Temple J., Ahmed A.A., et al. Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs. Cancer Cell 11 (2007) 498-512
-
(2007)
Cancer Cell
, vol.11
, pp. 498-512
-
-
Swanton, C.1
Marani, M.2
Pardo, O.3
Warne, P.H.4
Kelly, G.5
Sahai, E.6
Elustondo, F.7
Chang, J.8
Temple, J.9
Ahmed, A.A.10
-
31
-
-
34147198467
-
Synthetic lethal screen identification of chemosensitizer loci in cancer cells
-
Whitehurst A.W., Bodemann B.O., Cardenas J., Ferguson D., Girard L., Peyton M., Minna J.D., Michnoff C., Hao W., Roth M.G., et al. Synthetic lethal screen identification of chemosensitizer loci in cancer cells. Nature 446 (2007) 815-819
-
(2007)
Nature
, vol.446
, pp. 815-819
-
-
Whitehurst, A.W.1
Bodemann, B.O.2
Cardenas, J.3
Ferguson, D.4
Girard, L.5
Peyton, M.6
Minna, J.D.7
Michnoff, C.8
Hao, W.9
Roth, M.G.10
-
32
-
-
0030964233
-
Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens
-
Wilcken N.R., Prall O.W., Musgrove E.A., and Sutherland R.L. Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens. Clin. Cancer Res. 3 (1997) 849-854
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 849-854
-
-
Wilcken, N.R.1
Prall, O.W.2
Musgrove, E.A.3
Sutherland, R.L.4
-
33
-
-
0029960055
-
TRANSFAC: A database on transcription factors and their DNA binding sites
-
Wingender E., Dietze P., Karas H., and Knuppel R. TRANSFAC: A database on transcription factors and their DNA binding sites. Nucleic Acids Res. 24 (1996) 238-241
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 238-241
-
-
Wingender, E.1
Dietze, P.2
Karas, H.3
Knuppel, R.4
|