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1
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2042437650
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Initial sequencing and analysis of the human genome. International Human Genome Sequencing Consortium
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An outstanding census of mobile elements in the human genome.
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Lander E.S., Linton L.M., Birren B., Nusbaum C., Zody M.C., Baldwin J., Devon K., Dewar K., Doyle M., FitzHugh W.et al. Initial sequencing and analysis of the human genome. International Human Genome Sequencing Consortium. Nature. 409:2001;860-921 An outstanding census of mobile elements in the human genome.
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Nature
, vol.409
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Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
Fitzhugh, W.10
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2
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1542563409
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Initial sequencing and comparative analysis of the mouse genome
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A very good account of mobile elements in the mouse genome. Although the SINE analysis is quite good, the shotgun sequence approach does not allow a full accounting of L1 and LTR retrotransposon sequences. This paper includes extensive comparative genomics to the human genome.
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Waterston R.H., Lindblad-Toh K., Birney E., Rogers J., Abril J.F., Agarwal P., Agarwala R., Ainscough R., Alexandersson M., An P.et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 420:2002;520-562 A very good account of mobile elements in the mouse genome. Although the SINE analysis is quite good, the shotgun sequence approach does not allow a full accounting of L1 and LTR retrotransposon sequences. This paper includes extensive comparative genomics to the human genome.
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(2002)
Nature
, vol.420
, pp. 520-562
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Waterston, R.H.1
Lindblad-Toh, K.2
Birney, E.3
Rogers, J.4
Abril, J.F.5
Agarwal, P.6
Agarwala, R.7
Ainscough, R.8
Alexandersson, M.9
An, P.10
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3
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0031797726
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Human-specific integrations of the HERV-K endogenous retrovirus family
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Medstrand P., Mager D.L. Human-specific integrations of the HERV-K endogenous retrovirus family. J Virol. 72:1998;9782-9787.
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J Virol
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Medstrand, P.1
Mager, D.L.2
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4
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0036021446
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Insertional polymorphisms of ETn retrotransposons include a disruption of the wiz gene in C57BL/6 mice
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Baust C., Baillie G.J., Mager D.L. Insertional polymorphisms of ETn retrotransposons include a disruption of the wiz gene in C57BL/6 mice. Mamm Genome. 13:2002;423-428.
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Mamm Genome
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Baust, C.1
Baillie, G.J.2
Mager, D.L.3
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6
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0037965788
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Hot L1s account for the bulk of retrotransposition in the human population
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A comprehensive study measuring retrotransposition potential and population frequency for the most active subfamily of L1 elements in humans. It presents a 'snapshot' of the amplification potential of these elements.
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Brouha B., Schustak J., Badge R.M., Lutz-Prigge S., Farley A.H., Moran J.V., Kazazian H.H. Jr. Hot L1s account for the bulk of retrotransposition in the human population. Proc Natl Acad Sci USA. 100:2003;5280-5285 A comprehensive study measuring retrotransposition potential and population frequency for the most active subfamily of L1 elements in humans. It presents a 'snapshot' of the amplification potential of these elements.
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(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5280-5285
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Brouha, B.1
Schustak, J.2
Badge, R.M.3
Lutz-Prigge, S.4
Farley, A.H.5
Moran, J.V.6
Kazazian, H.H.Jr.7
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9
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0036250811
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Alu repeats and human genomic diversity
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Batzer M.A., Deininger P.L. Alu repeats and human genomic diversity. Nat Rev Genet. 3:2002;370-379.
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Nat Rev Genet
, vol.3
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Batzer, M.A.1
Deininger, P.L.2
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10
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0034128820
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The end of the LINE? Lack of recent L1 activity in a group of South American rodents
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Casavant N.C., Scott L., Cantrell M.A., Wiggins L.E., Baker R.J., Wichman H.A. The end of the LINE? Lack of recent L1 activity in a group of South American rodents. Genetics. 154:2000;1809-1817.
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Genetics
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Casavant, N.C.1
Scott, L.2
Cantrell, M.A.3
Wiggins, L.E.4
Baker, R.J.5
Wichman, H.A.6
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11
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0002404386
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Edited by Craig NL, Craigie R, Gellert M, Lambowitz AM. Washington, DC: ASM Press;
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Moran JV, Gilbert N: Mammalian LINE-1 Retrotransposons and Related Elements. Edited by Craig NL, Craigie R, Gellert M, Lambowitz AM. Washington, DC: ASM Press; 2002:836-869.
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Mammalian LINE-1 Retrotransposons and Related Elements.
, pp. 836-869
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Moran, J.V.1
Gilbert, N.2
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12
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0034161961
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Transduction of 3′-flanking sequences is common in L1 retrotransposition
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Goodier J.L., Ostertag E.M., Kazazian H.H. Jr. Transduction of 3′-flanking sequences is common in L1 retrotransposition. Hum Mol Genet. 9:2000;653-657.
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Hum Mol Genet
, vol.9
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Goodier, J.L.1
Ostertag, E.M.2
Kazazian, H.H.Jr.3
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13
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0342313559
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Frequent human genomic DNA transduction driven by LINE-1 retrotransposition
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Pickeral O.K., Makalowski W., Boguski M.S., Boeke J.D. Frequent human genomic DNA transduction driven by LINE-1 retrotransposition. Genome Res. 10:2000;411-415.
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Genome Res
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, pp. 411-415
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Pickeral, O.K.1
Makalowski, W.2
Boguski, M.S.3
Boeke, J.D.4
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14
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0037669011
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Trans mobilization of genomic DNA as a mechanism for retrotransposon- mediated exon shuffling
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Ejima Y., Yang L. Trans mobilization of genomic DNA as a mechanism for retrotransposon-mediated exon shuffling. Hum Mol Genet. 12:2003;1321-1328.
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Hum Mol Genet
, vol.12
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Ejima, Y.1
Yang, L.2
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15
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0041660958
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The human genome contains many types of chimeric retrogenes generated through in vivo RNA recombination
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This bioinformatic study suggests that the L1-encoded proteins can preferentially switch templates to other RNA transcripts, primarily those transcribed by RNA pol III, resulting in the formation of chimeric pseudogenes.
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Buzdin A., Gogvadze E., Kovalskaya E., Volchkov P., Ustyugova S., Illarionova A., Fushan A., Vinogradova T., Sverdlov E. The human genome contains many types of chimeric retrogenes generated through in vivo RNA recombination. Nucleic Acids Res. 31:2003;4385-4390 This bioinformatic study suggests that the L1-encoded proteins can preferentially switch templates to other RNA transcripts, primarily those transcribed by RNA pol III, resulting in the formation of chimeric pseudogenes.
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Nucleic Acids Res
, vol.31
, pp. 4385-4390
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Buzdin, A.1
Gogvadze, E.2
Kovalskaya, E.3
Volchkov, P.4
Ustyugova, S.5
Illarionova, A.6
Fushan, A.7
Vinogradova, T.8
Sverdlov, E.9
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16
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0034025077
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Homologous and nonhomologous recombination resulting in deletion: Effects of p53 status, microhomology, and repetitive DNA length and orientation
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Gebow D., Miselis N., Liber H.L. Homologous and nonhomologous recombination resulting in deletion: effects of p53 status, microhomology, and repetitive DNA length and orientation. Mol Cell Biol. 20:2000;4028-4035.
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Mol Cell Biol
, vol.20
, pp. 4028-4035
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Gebow, D.1
Miselis, N.2
Liber, H.L.3
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17
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0035902483
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Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences
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Zhou Z.H., Akgun E., Jasin M. Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences. Proc Natl Acad Sci USA. 98:2001;8326-8333.
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Proc Natl Acad Sci USA
, vol.98
, pp. 8326-8333
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Zhou, Z.H.1
Akgun, E.2
Jasin, M.3
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18
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0035147092
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Biased distribution of inverted and direct Alus in the human genome: Implications for insertion, exclusion, and genome stability
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Stenger J.E., Lobachev K.S., Gordenin D., Darden T.A., Jurka J., Resnick M.A. Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability. Genome Res. 11:2001;12-27.
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Genome Res
, vol.11
, pp. 12-27
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Stenger, J.E.1
Lobachev, K.S.2
Gordenin, D.3
Darden, T.A.4
Jurka, J.5
Resnick, M.A.6
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19
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0142059650
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An Alu transposition model for the origin and expansion of human segmental duplications
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in press.
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Bailey JA, Liu G, Eichler EE: An Alu transposition model for the origin and expansion of human segmental duplications. Am J Hum Genet 2003, in press.
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(2003)
Am J Hum Genet
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Bailey, J.A.1
Liu, G.2
Eichler, E.E.3
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20
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0036300478
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Non-traditional Alu evolution and primate genomic diversity
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This large-scale study demonstrates that Alu elements are essentially homoplasy-free genetic characters for phylogenetic and human population genetic studies, and documents widespread gene conversion within Alu elements.
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Roy-Engel A.M., Carroll M.L., El-Sawy M., Salem A.-H., Garber R.K., Nguyen S.V., Deininger P.L., Batzer M.A. Non-traditional Alu evolution and primate genomic diversity. J Mol Biol. 316:2002;1033-1040 This large-scale study demonstrates that Alu elements are essentially homoplasy-free genetic characters for phylogenetic and human population genetic studies, and documents widespread gene conversion within Alu elements.
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(2002)
J Mol Biol
, vol.316
, pp. 1033-1040
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Roy-Engel, A.M.1
Carroll, M.L.2
El-Sawy, M.3
Salem, A.-H.4
Garber, R.K.5
Nguyen, S.V.6
Deininger, P.L.7
Batzer, M.A.8
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21
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0038192415
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Continuous exchange of sequence information between dispersed Tc1 transposons in the Caenorhabditis elegans genome
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Fischer S.E., Wienholds E., Plasterk R.H. Continuous exchange of sequence information between dispersed Tc1 transposons in the Caenorhabditis elegans genome. Genetics. 164:2003;127-134.
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(2003)
Genetics
, vol.164
, pp. 127-134
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Fischer, S.E.1
Wienholds, E.2
Plasterk, R.H.3
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23
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0037047396
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Human L1 retrotransposition is associated with genetic instability in vivo
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•], this study shows that L1 is not simply an insertional mutagen in cultured cells but that retrotransposition can be accompanied with various forms of genetic instability.
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•], this study shows that L1 is not simply an insertional mutagen in cultured cells but that retrotransposition can be accompanied with various forms of genetic instability.
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(2002)
Cell
, vol.110
, pp. 327-338
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Symer, D.E.1
Connelly, C.2
Szak, S.T.3
Caputo, E.M.4
Cost, G.J.5
Parmigiani, G.6
Boeke, J.D.7
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24
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0033988576
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A double-strand break in a chromosomal LINE element can be repaired by gene conversion with various endogenous LINE elements in mouse cells
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Tremblay A., Jasin M., Chartrand P. A double-strand break in a chromosomal LINE element can be repaired by gene conversion with various endogenous LINE elements in mouse cells. Mol Cell Biol. 20:2000;54-60.
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Mol Cell Biol
, vol.20
, pp. 54-60
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Tremblay, A.1
Jasin, M.2
Chartrand, P.3
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25
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0342905062
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Members of the SRY family regulate the human LINE retrotransposons
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Tchenio T., Casella J.F., Heidmann T. Members of the SRY family regulate the human LINE retrotransposons. Nucleic Acids Res. 28:2000;411-415.
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(2000)
Nucleic Acids Res
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, pp. 411-415
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Tchenio, T.1
Casella, J.F.2
Heidmann, T.3
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26
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0345604433
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An important role for RUNX3 in human L1 transcription and retrotransposition
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Yang N., Zhang L., Zhang Y., Kazazian H.H. Jr. An important role for RUNX3 in human L1 transcription and retrotransposition. Nucleic Acids Res. 31:2003;4929-4940.
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(2003)
Nucleic Acids Res
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, pp. 4929-4940
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Yang, N.1
Zhang, L.2
Zhang, Y.3
Kazazian, H.H.Jr.4
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27
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0034999474
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Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes
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The author demonstrates that the L1 promoter is bidirectional. This may impact gene expression near L1 elements, and may have as yet uncharacterized influences on L1 expression.
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Speek M. Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes. Mol Cell Biol. 21:2001;1973-1985 The author demonstrates that the L1 promoter is bidirectional. This may impact gene expression near L1 elements, and may have as yet uncharacterized influences on L1 expression.
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(2001)
Mol Cell Biol
, vol.21
, pp. 1973-1985
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Speek, M.1
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28
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0034079713
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Human LINE retrotransposons generate processed pseudogenes
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Esnault C., Maestre J., Heidmann T. Human LINE retrotransposons generate processed pseudogenes. Nat Genet. 24:2000;363-367.
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Nat Genet
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Esnault, C.1
Maestre, J.2
Heidmann, T.3
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29
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0035144498
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Human L1 retrotransposition: Cis preference versus trans complementation
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Wei W., Gilbert N., Ooi S.L., Lawler J.F., Ostertag E.M., Kazazian H.H., Boeke J.D., Moran J.V. Human L1 retrotransposition: cis preference versus trans complementation. Mol Cell Biol. 21:2001;1429-1439.
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(2001)
Mol Cell Biol
, vol.21
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Wei, W.1
Gilbert, N.2
Ooi, S.L.3
Lawler, J.F.4
Ostertag, E.M.5
Kazazian, H.H.6
Boeke, J.D.7
Moran, J.V.8
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30
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0036847319
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Human L1 element target-primed reverse transcription in vitro
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The authors establish an experimental system to analyze the molecular mechanism for target primed reverse transcription of L1 elements.
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Cost G.J., Feng Q., Jacquier A., Boeke J.D. Human L1 element target-primed reverse transcription in vitro. EMBO J. 21:2002;5899-5910 The authors establish an experimental system to analyze the molecular mechanism for target primed reverse transcription of L1 elements.
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(2002)
EMBO J
, vol.21
, pp. 5899-5910
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Cost, G.J.1
Feng, Q.2
Jacquier, A.3
Boeke, J.D.4
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31
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0027450385
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Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition
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Luan D.D., Korman M.H., Jakubczak J.L., Eickbush T.H. Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition. Cell. 72:1993;595-605.
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Cell
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Luan, D.D.1
Korman, M.H.2
Jakubczak, J.L.3
Eickbush, T.H.4
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32
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0035163939
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Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE- 1 retrotransposon
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The first demonstration of a nucleic-acid chaperone activity, in addition to the known RNA binding, for the L1 ORF1 protein.
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Martin S.L., Bushman F.D. Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE- 1 retrotransposon. Mol Cell Biol. 21:2001;467-475 The first demonstration of a nucleic-acid chaperone activity, in addition to the known RNA binding, for the L1 ORF1 protein.
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Mol Cell Biol
, vol.21
, pp. 467-475
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Martin, S.L.1
Bushman, F.D.2
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33
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0035208118
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Twin priming: A proposed mechanism for the creation of inversions in L1 retrotransposition
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Provides a clear model of the priming events that cause inversions during L1 insertion. The mechanism of 'normal' L1 elements is still less clear.
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Ostertag E.M., Kazazian H.H. Jr. Twin priming: a proposed mechanism for the creation of inversions in L1 retrotransposition. Genome Res. 11:2001;2059-2065 Provides a clear model of the priming events that cause inversions during L1 insertion. The mechanism of 'normal' L1 elements is still less clear.
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Genome Res
, vol.11
, pp. 2059-2065
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Ostertag, E.M.1
Kazazian, H.H.Jr.2
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34
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0036613245
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DNA repair mediated by endonuclease-independent LINE-1 retrotransposition
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The authors reveal an endonuclease-independent pathway of L1 retrotransposition in Chinese hamster ovary cells, which is accentuated in cells defective for non-homologous end joining.
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Morrish T.A., Gilbert N., Myers J.S., Vincent B.J., Stamato T.D., Taccioli G.E., Batzer M.A., Moran J.V. DNA repair mediated by endonuclease-independent LINE-1 retrotransposition. Nat Genet. 31:2002;159-165 The authors reveal an endonuclease-independent pathway of L1 retrotransposition in Chinese hamster ovary cells, which is accentuated in cells defective for non-homologous end joining.
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(2002)
Nat Genet
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Morrish, T.A.1
Gilbert, N.2
Myers, J.S.3
Vincent, B.J.4
Stamato, T.D.5
Taccioli, G.E.6
Batzer, M.A.7
Moran, J.V.8
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35
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0003308786
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Molecular archeology of L1 insertions in the human genome
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research0052.
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Szak ST, Pickeral OK, Makalowski W, Boguski MS, Landsman D, Boeke JD: Molecular archeology of L1 insertions in the human genome. Genome Biol 2002, 3:research0052.
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Genome Biol
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Szak, S.T.1
Pickeral, O.K.2
Makalowski, W.3
Boguski, M.S.4
Landsman, D.5
Boeke, J.D.6
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36
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0041571675
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Recently integrated Alu elements and human genomic diversity
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Salem A.H., Kilroy G.E., Watkins W.S., Jorde L.B., Batzer M.A. Recently integrated Alu elements and human genomic diversity. Mol Biol Evol. 20:2003;1349-1361.
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Mol Biol Evol.
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Salem, A.H.1
Kilroy, G.E.2
Watkins, W.S.3
Jorde, L.B.4
Batzer, M.A.5
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37
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0036073862
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A comprehensive analysis of recently integrated human Ta L1 elements
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Myers J.S., Vincent B.J., Udall H., Watkins W.S., Morrish T.A., Kilroy G.E., Swergold G.D., Henke J., Henke L., Moran J.V.et al. A comprehensive analysis of recently integrated human Ta L1 elements. Am J Hum Genet. 71:2002;312-326.
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Am J Hum Genet
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Myers, J.S.1
Vincent, B.J.2
Udall, H.3
Watkins, W.S.4
Morrish, T.A.5
Kilroy, G.E.6
Swergold, G.D.7
Henke, J.8
Henke, L.9
Moran, J.V.10
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38
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0035949607
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Alu-mediated inactivation of the human CMP- N-acetylneuraminic acid hydroxylase gene
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Hayakawa T., Satta Y., Gagneux P., Varki A., Takahata N. Alu-mediated inactivation of the human CMP- N-acetylneuraminic acid hydroxylase gene. Proc Natl Acad Sci USA. 98:2001;11399-11404.
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Proc Natl Acad Sci USA
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Hayakawa, T.1
Satta, Y.2
Gagneux, P.3
Varki, A.4
Takahata, N.5
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39
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0041353551
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LINE-mediated retrotransposition of marked Alu sequences
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The authors establish an experimental test of SINE-related amplification in cultured cells. They demonstrate the absolute need for an A-tail, potential for increase of A-tail length during amplification, and that Alu amplification requires ORF2p, but not ORF1p from L1.
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Dewannieux M., Esnault C., Heidmann T. LINE-mediated retrotransposition of marked Alu sequences. Nat Genet. 35:2003;41-48 The authors establish an experimental test of SINE-related amplification in cultured cells. They demonstrate the absolute need for an A-tail, potential for increase of A-tail length during amplification, and that Alu amplification requires ORF2p, but not ORF1p from L1.
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Nat Genet
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Dewannieux, M.1
Esnault, C.2
Heidmann, T.3
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40
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0036849412
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LINEs mobilize SINEs in the eel through a shared 3′ sequence
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This paper provides direct experimental proof that the stringent SINEs are dependent on their cognate LINE for amplification.
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Kajikawa M., Okada N. LINEs mobilize SINEs in the eel through a shared 3′ sequence. Cell. 111:2002;433-444 This paper provides direct experimental proof that the stringent SINEs are dependent on their cognate LINE for amplification.
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Cell
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Kajikawa, M.1
Okada, N.2
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41
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0036899669
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A mouse model of human L1 retrotransposition
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The authors establish a mouse model for human L1 retrotransposition and demonstrate male germ cell transmission of L1.
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Ostertag E.M., DeBerardinis R.J., Goodier J.L., Zhang Y., Yang N., Gerton G.L., Kazazian H.H. Jr. A mouse model of human L1 retrotransposition. Nat Genet. 32:2002;655-660 The authors establish a mouse model for human L1 retrotransposition and demonstrate male germ cell transmission of L1.
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(2002)
Nat Genet
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Ostertag, E.M.1
Deberardinis, R.J.2
Goodier, J.L.3
Zhang, Y.4
Yang, N.5
Gerton, G.L.6
Kazazian, H.H.Jr.7
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42
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0036077271
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Evidence consistent with human L1 retrotransposition in maternal meiosis I
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Brouha B., Meischl C., Ostertag E., de Boer M., Zhang Y., Neijens H., Roos D., Kazazian H.H. Jr. Evidence consistent with human L1 retrotransposition in maternal meiosis I. Am J Hum Genet. 71:2002;327-336.
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Am J Hum Genet
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Brouha, B.1
Meischl, C.2
Ostertag, E.3
De Boer, M.4
Zhang, Y.5
Neijens, H.6
Roos, D.7
Kazazian, H.H.Jr.8
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44
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0037383453
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ATLAS: A system to selectively identify human-specific L1 insertions
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Badge R.M., Alisch R.S., Moran J.V. ATLAS: a system to selectively identify human-specific L1 insertions. Am J Hum Genet. 72:2003;823-838.
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Am J Hum Genet
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Badge, R.M.1
Alisch, R.S.2
Moran, J.V.3
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45
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0035215372
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Genomic characterization of recent human LINE-1 insertions: Evidence supporting random insertion
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Documents a PCR-based technique to find recent LINE-1 insertions in human DNA. The study suggests that L1 transcripts also may be primed internally to initiate TPRT.
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Ovchinnikov I., Troxel A.B., Swergold G.D. Genomic characterization of recent human LINE-1 insertions: evidence supporting random insertion. Genome Res. 11:2001;2050-2058 Documents a PCR-based technique to find recent LINE-1 insertions in human DNA. The study suggests that L1 transcripts also may be primed internally to initiate TPRT.
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Ovchinnikov, I.1
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Active Alu element 'A-tails'; Size does matter
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The authors of this manuscript describe the relationship between long A-tails on Alu elements and their recent amplification rates, suggesting that A-tail length may be the primary factor controlling Alu activity. They further characterize the instability of these A-tails in the genome.
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Roy-Engel A.M., Salem A.-H., Oyeniran O.O., Deininger L.A., Hedges D.J., Kilroy G.E., Batzer M.A., Deininger P.L. Active Alu element 'A-tails'; size does matter. Genome Res. 12:2002;1333-1344 The authors of this manuscript describe the relationship between long A-tails on Alu elements and their recent amplification rates, suggesting that A-tail length may be the primary factor controlling Alu activity. They further characterize the instability of these A-tails in the genome.
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Genome Res
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Roy-Engel, A.M.1
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Muddashetty R.S., Khanam T., Kondrashov A., Bundman M., Iacoangeli A., Kremerskothen J., Duning K., Barnekow A., Huttenhofer A., Tiedge H.et al. Poly(A) binding protein is associated with neuronal BC1 and BC200 ribonucleoprotein particles. J Mol Biol. 321:2002;433-445.
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These authors demonstrate that LINE elements are homoplasy-free genetic characters in the Hominid lineage. The absence of homoplasy makes mobile element insertions a unique source of genetic variation for phylogenetic and population genetics studies.
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Vincent B.J., Myers J.S., Ho H.J., Kilroy G.E., Walker J.A., Watkins W.S., Jorde L.B., Batzer M.A. Following the LINEs: an analysis of primate genomic variation at human-specific LINE-1 insertion sites. Mol Biol Evol. 20:2003;1338-1348 These authors demonstrate that LINE elements are homoplasy-free genetic characters in the Hominid lineage. The absence of homoplasy makes mobile element insertions a unique source of genetic variation for phylogenetic and population genetics studies.
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Nikaido et al. demonstrate the utility of mobile element insertions for resolving phylogenetic relationships.
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Nikaido M., Matsuno F., Hamilton H., Brownell R.L. Jr., Cao Y., Ding W., Zuoyan Z., Shedlock A.M., Fordyce R.E., Hasegawa M.et al. Retroposon analysis of major cetacean lineages: the monophyly of toothed whales and the paraphyly of river dolphins. Proc Natl Acad Sci USA. 98:2001;7384-7389 Nikaido et al. demonstrate the utility of mobile element insertions for resolving phylogenetic relationships.
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Nikaido, M.1
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Alu elements and hominid phylogenetics
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in press
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Salem A-H, Ray DA, Xing J, Callinan PA, Myers JS, Hedges DJ, Garber RK, Witherspoon DJ, Jorde LB, Batzer MA: Alu elements and hominid phylogenetics. Proc Nat Acad Sci USA 2003, in press.
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Salem, A.-H.1
Ray, D.A.2
Xing, J.3
Callinan, P.A.4
Myers, J.S.5
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Garber, R.K.7
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Ma, B.10
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Mathews L.M., Chi S.Y., Greenberg N., Ovchinnikov I., Swergold G.D. Large differences between LINE-1 amplification rates in the human and chimpanzee lineages. Am J Hum Genet. 72:2003;739-748.
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Human population genetic structure and inference of group membership
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The authors demonstrate the utility of mobile element insertion polymorphisms for determining the origin of unknown human DNA samples.
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Bamshad M.J., Wooding S., Watkins W.S., Ostler C.T., Batzer M.A., Jorde L.B. Human population genetic structure and inference of group membership. Am J Hum Genet. 72:2003;578-589 The authors demonstrate the utility of mobile element insertion polymorphisms for determining the origin of unknown human DNA samples.
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Bamshad, M.J.1
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Watkins W.S., Rogers A.R., Ostler C.T., Wooding S., Bamshad M.J., Brassington A.M., Carroll M.L., Nguyen S.V., Walker J.A., Prasad B.V.et al. Genetic variation among world populations: inferences from 100 Alu insertion polymorphisms. Genome Res. 13:2003;1607-1618.
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Watkins, W.S.1
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Wooding, S.4
Bamshad, M.J.5
Brassington, A.M.6
Carroll, M.L.7
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Walker, J.A.9
Prasad, B.V.10
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Medstrand P., van de Lagemaat L.N., Mager D.L. Retroelement distributions in the human genome: variations associated with age and proximity to genes. Genome Res. 12:2002;1483-1495.
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Brookfield J.F. Selection on Alu sequences? Curr Biol. 11:2001;R900-R901.
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Greally J.M. Short interspersed transposable elements (SINEs) are excluded from imprinted regions in the human genome. Proc Natl Acad Sci USA. 99:2002;327-332.
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Bailey J.A., Carrel L., Chakravarti A., Eichler E.E. Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: the Lyon repeat hypothesis. Proc Natl Acad Sci USA. 97:2000;6634-6639.
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Boissinot S., Entezam A., Furano A.V. Selection against deleterious LINE-1-containing loci in the human lineage. Mol Biol Evol. 18:2001;926-935.
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Boissinot, S.1
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