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Volumn 343, Issue 19, 2000, Pages 1350-1354

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CARMUSTINE;

EID: 0034626988     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200011093431901     Document Type: Article
Times cited : (1990)

References (19)
  • 1
    • 0002355158 scopus 로고    scopus 로고
    • Antitumor alkylating agents
    • DeVita VT Jr, Hellman S, Rosenberg SA, eds. Cancer: principles and practice of oncology. 5th ed. Philadelphia: Lippincott-Raven
    • (1997) , vol.1 , pp. 405-418
    • Teicher, B.A.1
  • 3
    • 0025116511 scopus 로고
    • DNA alkylation by the haloethylnitrosoureas: Nature of modifications produced and their enzymatic repair or removal
    • (1990) Mutat Res , vol.233 , pp. 117-126
    • Ludlum, D.B.1
  • 7
    • 13344282752 scopus 로고    scopus 로고
    • Retrospective study of the correlation between the DNA repair protein alkyltransferase and survival of brain tumor patients treated with carmustine
    • (1996) Cancer Res , vol.56 , pp. 783-788
    • Belanich, M.1    Pastor, M.2    Randall, T.3
  • 8
    • 0031595389 scopus 로고    scopus 로고
    • Correlation of tumor O6 methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: A Southwest Oncology Group study
    • (1998) J Clin Oncol , vol.16 , pp. 3310-3315
    • Jaeckle, K.A.1    Eyre, H.J.2    Townsend, J.J.3
  • 11
    • 0030823671 scopus 로고    scopus 로고
    • Methylation hot spots in the 5' flanking region denote silencing of the O6-methylguanine-DNA methyltransferase gene
    • (1997) Cancer Res , vol.57 , pp. 3672-3677
    • Qian, X.C.1    Brent, T.P.2
  • 15
    • 19244370208 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
    • (2000) Cancer Res , vol.60 , pp. 2368-2371
    • Esteller, M.1    Toyota, M.2    Sanchez-Cespedes, M.3
  • 19
    • 0025196019 scopus 로고
    • Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 5368-5372
    • Dolan, M.E.1    Moschel, P.C.2    Pegg, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.