Handling drawbacks of mass spectrometric detection coupled to liquid chromatography in bioanalysis

Journal of Liquid Chromatography and Related Technologies

Volumn 33, Issue 9-12, 2010, Pages 1255-1286

  Medvedovici, Andrei ^a   Albu, Florin ^b   David, Victor ^a  

^a UNIVERSITY OF BUCHAREST   (Romania)

^b LaborMed Pharma SA   (Romania)

Author keywords

adduct formation; carryover effects; instrumental response functions; instrumental variety; LC MS hyphenation; matrix effects; precision; related drawbacks; structural identification and confirmation

Indexed keywords

ADDUCT FORMATION; CARRY-OVER EFFECTS; INSTRUMENTAL RESPONSE FUNCTION; MATRIX EFFECTS; STRUCTURAL IDENTIFICATION;

ATMOSPHERIC PRESSURE; INSTRUMENTS; ION SOURCES; IONIZATION OF LIQUIDS; IONS; LIQUIDS; MASS SPECTROMETRY; PARTICLE DETECTORS; STRUCTURAL ANALYSIS;

LIQUID CHROMATOGRAPHY;

ATMOSPHERIC PRESSURE; BIOCHEMICAL COMPOSITION; CHEMICAL STRUCTURE; ERRORS, ARTIFACTS AND QUALITY CONTROL PROCEDURES; FRAGMENTATION REACTION; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONLINEAR SYSTEM; PHASE SEPARATION; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REVIEW; SENSITIVITY AND SPECIFICITY; SIGNAL DETECTION; STEREOCHEMISTRY; STRUCTURE ANALYSIS; VALIDITY;

EID: 77954694202     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2010.484375     Document Type: Review

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