Considerations on MS/MS detection of bromazepam after liquid chromatographic separation from plasma samples: Application to a bioequivalence study

Journal of Liquid Chromatography and Related Technologies

Volumn 30, Issue 18, 2007, Pages 2699-2715

  Albu, Florin ^a   Georgita, Cristina ^a   Tache, Florentin ^b   Mutihac, Lucia ^b   Medvedovici, Andrei ^b   David, Victor ^b  

^a LaborMed Pharma SA   (Romania)

^b UNIVERSITY OF BUCHAREST   (Romania)

Author keywords

API ESI; Benzodiazepines; Extraction less sample preparation method; Human plasma; IT TQ

Indexed keywords

ATMOSPHERIC PRESSURE CHEMICAL IONIZATION (API); BENZODIAZEPINES; EXTRACTION LESS SAMPLE PREPARATION METHOD; HUMAN PLASMA;

ACETONITRILE; FORMIC ACID; PHASE SEPARATION; PLASMA (HUMAN); PRECIPITATION (CHEMICAL); PROTEINS;

LIQUID CHROMATOGRAPHY;

BROMAZEPAM; FORMIC ACID; METHANOL; NITRAZEPAM; UNCLASSIFIED DRUG; ZORBAX;

ACCURACY; ADULT; ANALYTICAL EQUIPMENT; ANALYZER; ARTICLE; BIOEQUIVALENCE; BLOOD SAMPLING; CLINICAL TRIAL; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HUMAN; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MONITORING; NORMAL HUMAN; OPEN STUDY; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ANALYSIS; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; STANDARD; TABLET FORMULATION; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

EID: 34548058122     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070701560603     Document Type: Article

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